{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T13:42:50Z","timestamp":1762954970357},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2010,10,7]],"date-time":"2010-10-07T00:00:00Z","timestamp":1286409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2010,10,7]],"date-time":"2010-10-07T00:00:00Z","timestamp":1286409600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Hum Hypertens"],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1038\/jhh.2010.93","type":"journal-article","created":{"date-parts":[[2010,10,7]],"date-time":"2010-10-07T09:23:07Z","timestamp":1286443387000},"page":"560-564","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Further study of chromosome 7p22 to identify the molecular basis of familial hyperaldosteronism type II"],"prefix":"10.1038","volume":"25","author":[{"given":"K J","family":"Carss","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Stowasser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R D","family":"Gordon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K M","family":"O'Shaughnessy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,10,7]]},"reference":[{"issue":"2","key":"BFjhh201093_CR1","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1291\/hypres.30.111","volume":"30","author":"R Fogari","year":"2007","unstructured":"Fogari R, Preti P, Zoppi A, Rinaldi A, Fogari E, Mugellini A . Prevalence of primary aldosteronism among unselected hypertensive patients: a prospective study based on the use of an aldosterone\/renin ratio above 25 as a screening test. Hypertens Res 2007; 30 (2): 111\u2013117.","journal-title":"Hypertens Res"},{"issue":"9","key":"BFjhh201093_CR2","first-page":"3214","volume":"83","author":"DJ Torpy","year":"1998","unstructured":"Torpy DJ, Gordon RD, Lin JP, Huggard PR, Taymans SE, Stowasser M et al. Familial hyperaldosteronism type II: description of a large kindred and exclusion of the aldosterone synthase (CYP11B2) gene. J Clin Endocrinol Metab 1998; 83 (9): 3214\u20133218.","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"BFjhh201093_CR3","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1111\/j.1440-1681.1991.tb01446.x","volume":"18","author":"RD Gordon","year":"1991","unstructured":"Gordon RD, Stowasser M, Tunny TJ, Klemm SA, Finn WL, Krek AL . Clinical and pathological diversity of primary aldosteronism, including a new familial variety. Clin Exp Pharmacol Physiol 1991; 18 (5): 283\u2013286.","journal-title":"Clin Exp Pharmacol Physiol"},{"issue":"11","key":"BFjhh201093_CR4","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1136\/jmg.37.11.831","volume":"37","author":"AR Lafferty","year":"2000","unstructured":"Lafferty AR, Torpy DJ, Stowasser M, Taymans SE, Lin JP, Huggard P et al. A novel genetic locus for low renin hypertension: familial hyperaldosteronism type II maps to chromosome 7 (7p22). J Med Genet 2000; 37 (11): 831\u2013835.","journal-title":"J Med Genet"},{"issue":"8","key":"BFjhh201093_CR5","doi-asserted-by":"publisher","first-page":"1477","DOI":"10.1097\/01.hjh.0000174299.66369.26","volume":"23","author":"A So","year":"2005","unstructured":"So A, Duffy DL, Gordon RD, Jeske YW, Lin-Su K, New MI et al. Familial hyperaldosteronism type II is linked to the chromosome 7p22 region but also shows predicted heterogeneity. J Hypertens 2005; 23 (8): 1477\u20131484.","journal-title":"J Hypertens"},{"issue":"6","key":"BFjhh201093_CR6","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1111\/j.1365-2265.2004.02155.x","volume":"61","author":"MS Elphinstone","year":"2004","unstructured":"Elphinstone MS, Gordon RD, So A, Jeske YW, Stratakis CA, Stowasser M . Genomic structure of the human gene for protein kinase A regulatory subunit R1-beta (PRKAR1B) on 7p22: no evidence for mutations in familial hyperaldosteronism type II in a large affected kindred. Clin Endocrinol (Oxf) 2004; 61 (6): 716\u2013723.","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"4","key":"BFjhh201093_CR7","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1111\/j.1440-1681.2008.04882.x","volume":"35","author":"YW Jeske","year":"2008","unstructured":"Jeske YW, So A, Kelemen L, Sukor N, Willys C, Bulmer B et al. Examination of chromosome 7p22 candidate genes RBaK, PMS2 and GNA12 in familial hyperaldosteronism type II. Clin Exp Pharmacol Physiol 2008; 35 (4): 380\u2013385.","journal-title":"Clin Exp Pharmacol Physiol"},{"issue":"4","key":"BFjhh201093_CR8","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1161\/01.HYP.0000258554.87444.91","volume":"49","author":"C Newton-Cheh","year":"2007","unstructured":"Newton-Cheh C, Guo CY, Gona P, Larson MG, Benjamin EJ, Wang TJ et al. Clinical and genetic correlates of aldosterone-to-renin ratio and relations to blood pressure in a community sample. Hypertension 2007; 49 (4): 846\u2013856.","journal-title":"Hypertension"},{"issue":"3","key":"BFjhh201093_CR9","first-page":"751","volume":"25","author":"JT Huang","year":"2004","unstructured":"Huang JT, Lee V . Identification and characterization of a novel human FOXK1 gene in silico. Int J Oncol 2004; 25 (3): 751\u2013757.","journal-title":"Int J Oncol"},{"issue":"7050","key":"BFjhh201093_CR10","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1038\/nature03799","volume":"436","author":"AJ Minn","year":"2005","unstructured":"Minn AJ, Gupta GP, Siegel PM, Bos PD, Shu W, Giri DD et al. Genes that mediate breast cancer metastasis to lung. Nature 2005; 436 (7050): 518\u2013524.","journal-title":"Nature"},{"issue":"45","key":"BFjhh201093_CR11","doi-asserted-by":"publisher","first-page":"34592","DOI":"10.1074\/jbc.M604019200","volume":"281","author":"C Fearns","year":"2006","unstructured":"Fearns C, Pan Q, Mathison JC, Chuang TH . Triad3A regulates ubiquitination and proteasomal degradation of RIP1 following disruption of Hsp90 binding. J Biol Chem 2006; 281 (45): 34592\u201334600.","journal-title":"J Biol Chem"},{"issue":"23","key":"BFjhh201093_CR12","doi-asserted-by":"publisher","first-page":"7971","DOI":"10.1128\/MCB.21.23.7971-7980.2001","volume":"21","author":"L Lu","year":"2001","unstructured":"Lu L, Han AP, Chen JJ . Translation initiation control by heme-regulated eukaryotic initiation factor 2alpha kinase in erythroid cells under cytoplasmic stresses. Mol Cell Biol 2001; 21 (23): 7971\u20137980.","journal-title":"Mol Cell Biol"},{"issue":"3","key":"BFjhh201093_CR13","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1083\/jcb.200801047","volume":"181","author":"D Michaelson","year":"2008","unstructured":"Michaelson D, Abidi W, Guardavaccaro D, Zhou M, Ahearn I, Pagano M et al. Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division. J Cell Biol 2008; 181 (3): 485\u2013496.","journal-title":"J Cell Biol"},{"key":"BFjhh201093_CR14","first-page":"365","volume":"132","author":"S Rozen","year":"2000","unstructured":"Rozen S, Skaletsky H . Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol 2000; 132: 365\u2013386.","journal-title":"Methods Mol Biol"},{"issue":"13","key":"BFjhh201093_CR15","doi-asserted-by":"publisher","first-page":"1181","DOI":"10.1056\/NEJMoa0908094","volume":"362","author":"JR Lupski","year":"2010","unstructured":"Lupski JR, Reid JG, Gonzaga-Jauregui C, Rio Deiros D, Chen DC, Nazareth L et al. Whole-genome sequencing in a patient with Charcot-Marie-Tooth neuropathy. N Engl J Med 2010; 362 (13): 1181\u20131191.","journal-title":"N Engl J Med"},{"issue":"1","key":"BFjhh201093_CR16","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1038\/ng.499","volume":"42","author":"SB Ng","year":"2010","unstructured":"Ng SB, Buckingham KJ, Lee C, Bigham AW, Tabor HK, Dent KM et al. Exome sequencing identifies the cause of a mendelian disorder. Nat Genet 2010; 42 (1): 30\u201335.","journal-title":"Nat Genet"},{"issue":"1","key":"BFjhh201093_CR17","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1038\/ng0598-47","volume":"19","author":"SD Dreyer","year":"1998","unstructured":"Dreyer SD, Zhou G, Baldini A, Winterpacht A, Zabel B, Cole W et al. Mutations in LMX1B cause abnormal skeletal patterning and renal dysplasia in nail patella syndrome. Nat Genet 1998; 19 (1): 47\u201350.","journal-title":"Nat Genet"},{"key":"BFjhh201093_CR18","first-page":"95","volume":"41","author":"TA Hall","year":"1999","unstructured":"Hall TA . BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95\/98\/NT. Nucleic Acids Symp Ser 1999; 41: 95\u201398.","journal-title":"Nucleic Acids Symp Ser"},{"issue":"6968","key":"BFjhh201093_CR19","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1038\/nature02168","volume":"426","author":"International HapMap Consortium","year":"2003","unstructured":"International HapMap Consortium. The International HapMap Project. Nature 2003; 426 (6968): 789\u2013796.","journal-title":"Nature"},{"issue":"5532","key":"BFjhh201093_CR20","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1126\/science.1062844","volume":"293","author":"FH Wilson","year":"2001","unstructured":"Wilson FH, Disse-Nicodeme S, Choate KA, Ishikawa K, Nelson-Williams C, Desitter I et al. Human hypertension caused by mutations in WNK kinases. Science 2001; 293 (5532): 1107\u20131112.","journal-title":"Science"},{"issue":"1","key":"BFjhh201093_CR21","doi-asserted-by":"publisher","first-page":"13.1","DOI":"10.1186\/gm13","volume":"1","author":"PD Stenson","year":"2009","unstructured":"Stenson PD, Mort M, Ball EV, Howells K, Phillips AD, Thomas NS et al. The human gene mutation database: 2008 update. Genome Med 2009; 1 (1): 13.1\u201313.6.","journal-title":"Genome Med"},{"issue":"6","key":"BFjhh201093_CR22","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1038\/ng.581","volume":"42","author":"A Hoischen","year":"2010","unstructured":"Hoischen A, van Bon BW, Gilissen C, Arts P, van Lier B, Steehouwer M et al. De novo mutations of SETBP1 cause Schinzel-Giedion syndrome. Nat Genet 2010; 42 (6): 483\u2013485.","journal-title":"Nat Genet"},{"issue":"2","key":"BFjhh201093_CR23","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/j.ajhg.2009.12.016","volume":"86","author":"K Nikopoulos","year":"2010","unstructured":"Nikopoulos K, Gilissen C, Hoischen A, van Nouhuys CE, Boonstra FN, Blokland EA et al. Next-generation sequencing of a 40\u2009Mb linkage interval reveals TSPAN12 mutations in patients with familial exudative vitreoretinopathy. Am J Hum Genet 2010; 86 (2): 240\u2013247.","journal-title":"Am J Hum Genet"}],"container-title":["Journal of Human Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/jhh201093.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/jhh201093","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/jhh201093.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,17]],"date-time":"2022-03-17T20:09:11Z","timestamp":1647547751000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/jhh201093"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10,7]]},"references-count":23,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["BFjhh201093"],"URL":"https:\/\/doi.org\/10.1038\/jhh.2010.93","relation":{},"ISSN":["0950-9240","1476-5527"],"issn-type":[{"value":"0950-9240","type":"print"},{"value":"1476-5527","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,10,7]]},"assertion":[{"value":"15 July 2010","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 August 2010","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 October 2010","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}