{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T20:26:11Z","timestamp":1784751971761,"version":"3.55.0"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2013,7,25]],"date-time":"2013-07-25T00:00:00Z","timestamp":1374710400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2013,7,25]],"date-time":"2013-07-25T00:00:00Z","timestamp":1374710400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Hum Hypertens"],"published-print":{"date-parts":[[2014,2]]},"DOI":"10.1038\/jhh.2013.70","type":"journal-article","created":{"date-parts":[[2013,7,25]],"date-time":"2013-07-25T09:36:55Z","timestamp":1374745015000},"page":"92-97","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Alterations in vascular function in primary aldosteronism: a cardiovascular magnetic resonance imaging study"],"prefix":"10.1038","volume":"28","author":[{"given":"P B","family":"Mark","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Boyle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L U","family":"Zimmerli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E P","family":"McQuarrie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Delles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E M","family":"Freel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,7,25]]},"reference":[{"issue":"11","key":"BFjhh201370_CR1","doi-asserted-by":"publisher","first-page":"2293","DOI":"10.1016\/j.jacc.2006.07.059","volume":"48","author":"GP Rossi","year":"2006","unstructured":"Rossi GP, Bernini G, Caliumi C, Desideri G, Fabris B, Ferri C et al. A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients. J Am Coll Cardiol 2006; 48 (11): 2293\u20132300.","journal-title":"J Am Coll Cardiol"},{"issue":"6","key":"BFjhh201370_CR2","doi-asserted-by":"publisher","first-page":"892","DOI":"10.1161\/01.HYP.0000040261.30455.B6","volume":"40","author":"DA Calhoun","year":"2002","unstructured":"Calhoun DA, Nishizaka MK, Zaman MA, Thakkar RB, Weissmann P . Hyperaldosteronism among black and white subjects with resistant hypertension. Hypertension 2002; 40 (6): 892\u2013896.","journal-title":"Hypertension"},{"issue":"8","key":"BFjhh201370_CR3","doi-asserted-by":"publisher","first-page":"1243","DOI":"10.1016\/j.jacc.2005.01.015","volume":"45","author":"P Milliez","year":"2005","unstructured":"Milliez P, Girerd X, Plouin PF, Blacher J, Safar ME, Mourad JJ . Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism. J Am Coll Cardiol 2005; 45 (8): 1243\u20131248.","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"BFjhh201370_CR4","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1001\/archinternmed.2007.33","volume":"168","author":"C Catena","year":"2008","unstructured":"Catena C, Colussi G, Nadalini E, Chiuch A, Baroselli S, Lapenna R et al. Cardiovascular outcomes in patients with primary aldosteronism after treatment. Arch Intern Med 2008; 168 (1): 80\u201385.","journal-title":"Arch Intern Med"},{"issue":"3","key":"BFjhh201370_CR5","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1053\/j.ajkd.2010.10.047","volume":"57","author":"A Tomaschitz","year":"2011","unstructured":"Tomaschitz A, Pilz S, Ritz E, Grammer T, Drechsler C, Boehm BO et al. Association of plasma aldosterone with cardiovascular mortality in patients with low estimated GFR: the Ludwigshafen Risk and Cardiovascular Health (LURIC) Study. Am J Kidney Dis 2011; 57 (3): 403\u2013414.","journal-title":"Am J Kidney Dis"},{"issue":"7","key":"BFjhh201370_CR6","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1016\/S1043-2760(01)00432-5","volume":"12","author":"R Rocha","year":"2001","unstructured":"Rocha R, Stier CT Jr . Pathophysiological effects of aldosterone in cardiovascular tissues. Trends Endocrinol Metab 2001; 12 (7): 308\u2013314.","journal-title":"Trends Endocrinol Metab"},{"issue":"2","key":"BFjhh201370_CR7","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1210\/er.2007-0030","volume":"29","author":"JM Connell","year":"2008","unstructured":"Connell JM, MacKenzie SM, Freel EM, Fraser R, Davies E . A lifetime of aldosterone excess: long-term consequences of altered regulation of aldosterone production for cardiovascular function. Endocr Rev 2008; 29 (2): 133\u2013154.","journal-title":"Endocr Rev"},{"issue":"7","key":"BFjhh201370_CR8","doi-asserted-by":"publisher","first-page":"2638","DOI":"10.1210\/jc.2006-0101","volume":"91","author":"D Rizzoni","year":"2006","unstructured":"Rizzoni D, Paiardi S, Rodella L, Porteri E, De Ciuceis C, Rezzani R et al. Changes in extracellular matrix in subcutaneous small resistance arteries of patients with primary aldosteronism. J Clin Endocrinol Metab 2006; 91 (7): 2638\u20132642.","journal-title":"J Clin Endocrinol Metab"},{"issue":"7","key":"BFjhh201370_CR9","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1097\/HJH.0b013e3281268532","volume":"25","author":"R Holaj","year":"2007","unstructured":"Holaj R, Zelinka T, Wichterle D, Petrak O, Strauch B, Widimsky J Jr . Increased intima-media thickness of the common carotid artery in primary aldosteronism in comparison with essential hypertension. J Hypertens 2007; 25 (7): 1451\u20131457.","journal-title":"J Hypertens"},{"issue":"2","key":"BFjhh201370_CR10","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1016\/j.mce.2011.06.014","volume":"350","author":"A McCurley","year":"2012","unstructured":"McCurley A, Jaffe IZ . Mineralocorticoid receptors in vascular function and disease. Mol Cell Endocrinol 2012; 350 (2): 256\u2013265.","journal-title":"Mol Cell Endocrinol"},{"issue":"4","key":"BFjhh201370_CR11","doi-asserted-by":"publisher","first-page":"1032","DOI":"10.1161\/01.HYP.0000176588.51027.35","volume":"46","author":"GE Callera","year":"2005","unstructured":"Callera GE, Montezano AC, Yogi A, Tostes RC, He Y, Schiffrin EL et al. c-Src-dependent nongenomic signaling responses to aldosterone are increased in vascular myocytes from spontaneously hypertensive rats. Hypertension 2005; 46 (4): 1032\u20131038.","journal-title":"Hypertension"},{"issue":"6","key":"BFjhh201370_CR12","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1161\/01.HYP.0000128420.01881.aa","volume":"43","author":"GF Mitchell","year":"2004","unstructured":"Mitchell GF, Parise H, Benjamin EJ, Larson MG, Keyes MJ, Vita JA et al. Changes in arterial stiffness and wave reflection with advancing age in healthy men and women: the Framingham Heart Study. Hypertension 2004; 43 (6): 1239\u20131245.","journal-title":"Hypertension"},{"issue":"1","key":"BFjhh201370_CR13","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.atherosclerosis.2005.08.019","volume":"187","author":"MJ van Trijp","year":"2006","unstructured":"van Trijp MJ, Bos WJ, van der Schouw YT, Muller M, Grobbee DE, Bots ML . Non-invasively measured structural and functional arterial characteristics and coronary heart disease risk in middle aged and elderly men. Atherosclerosis 2006; 187 (1): 110\u2013115.","journal-title":"Atherosclerosis"},{"issue":"21","key":"BFjhh201370_CR14","doi-asserted-by":"publisher","first-page":"2588","DOI":"10.1093\/eurheartj\/ehl254","volume":"27","author":"S Laurent","year":"2006","unstructured":"Laurent S, Cockcroft J, Van Bortel L, Boutouyrie P, Giannattasio C, Hayoz D et al. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur Heart J 2006; 27 (21): 2588\u20132605.","journal-title":"Eur Heart J"},{"issue":"9","key":"BFjhh201370_CR15","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1016\/j.amjhyper.2006.02.002","volume":"19","author":"B Strauch","year":"2006","unstructured":"Strauch B, Petrak O, Wichterle D, Zelinka T, Holaj R, Widimsky J Jr . Increased arterial wall stiffness in primary aldosteronism in comparison with essential hypertension. Am J Hypertens 2006; 19 (9): 909\u2013914.","journal-title":"Am J Hypertens"},{"issue":"1","key":"BFjhh201370_CR16","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/j.atherosclerosis.2011.12.003","volume":"221","author":"YH Lin","year":"2012","unstructured":"Lin YH, Lin LY, Chen A, Wu XM, Lee JK, Su TC et al. Adrenalectomy improves increased carotid intima-media thickness and arterial stiffness in patients with aldosterone producing adenoma. Atherosclerosis 2012; 221 (1): 154\u2013159.","journal-title":"Atherosclerosis"},{"issue":"1","key":"BFjhh201370_CR17","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1038\/sj.ki.5002024","volume":"71","author":"LU Zimmerli","year":"2007","unstructured":"Zimmerli LU, Mark PB, Steedman T, Foster JE, Berg GA, Dargie HJ et al. Vascular function in patients with end-stage renal disease and\/or coronary artery disease: a cardiac magnetic resonance imaging study. Kidney Int 2007; 71 (1): 68\u201373.","journal-title":"Kidney Int"},{"issue":"11","key":"BFjhh201370_CR18","doi-asserted-by":"publisher","first-page":"1221","DOI":"10.1016\/S0002-9149(02)02838-2","volume":"90","author":"P Rerkpattanapipat","year":"2002","unstructured":"Rerkpattanapipat P, Hundley WG, Link KM, Brubaker PH, Hamilton CA, Darty SN et al. Relation of aortic distensibility determined by magnetic resonance imaging in patients &gt;or =60 years of age to systolic heart failure and exercise capacity. Am J Cardiol 2002; 90 (11): 1221\u20131225.","journal-title":"Am J Cardiol"},{"issue":"9","key":"BFjhh201370_CR19","doi-asserted-by":"publisher","first-page":"3266","DOI":"10.1210\/jc.2008-0104","volume":"93","author":"JW Funder","year":"2008","unstructured":"Funder JW, Carey RM, Fardella C, Gomez-Sanchez CE, Mantero F, Stowasser M et al. Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 2008; 93 (9): 3266\u20133281.","journal-title":"J Clin Endocrinol Metab"},{"issue":"3","key":"BFjhh201370_CR20","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1161\/CIRCIMAGING.111.971804","volume":"5","author":"OJ Rider","year":"2012","unstructured":"Rider OJ, Holloway CJ, Emmanuel Y, Bloch E, Clarke K, Neubauer S . Increasing plasma free fatty acids in healthy subjects induces aortic distensibility changes seen in obesity. Circ Cardiovasc Imaging 2012; 5 (3): 367\u2013375.","journal-title":"Circ Cardiovasc Imaging"},{"issue":"1","key":"BFjhh201370_CR21","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1186\/1532-429X-10-39","volume":"10","author":"PB Mark","year":"2008","unstructured":"Mark PB, Doyle A, Blyth KG, Patel RK, Weir RA, Steedman T et al. Vascular function assessed with cardiovascular magnetic resonance predicts survival in patients with advanced chronic kidney disease. J Cardiovasc Magn Reson 2008; 10 (1): 39.","journal-title":"J Cardiovasc Magn Reson"},{"issue":"1","key":"BFjhh201370_CR22","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/S0891-5849(99)00228-2","volume":"28","author":"B Fink","year":"2000","unstructured":"Fink B, Dikalov S, Bassenge E . A new approach for extracellular spin trapping of nitroglycerin-induced superoxide radicals both in vitro and in vivo. Free Radic Biol Med 2000; 28 (1): 121\u2013128.","journal-title":"Free Radic Biol Med"},{"issue":"1","key":"BFjhh201370_CR23","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/j.atherosclerosis.2010.01.014","volume":"211","author":"C Delles","year":"2010","unstructured":"Delles C, Dymott JA, Neisius U, Rocchiccioli JP, Bryce GJ, Moreno MU et al. Reduced LDL-cholesterol levels in patients with coronary artery disease are paralleled by improved endothelial function: An observational study in patients from 2003 and 2007. Atherosclerosis 2010; 211 (1): 271\u2013277.","journal-title":"Atherosclerosis"},{"issue":"12","key":"BFjhh201370_CR24","doi-asserted-by":"publisher","first-page":"2399","DOI":"10.1097\/HJH.0b013e32831286fd","volume":"26","author":"G Bernini","year":"2008","unstructured":"Bernini G, Galetta F, Franzoni F, Bardini M, Taurino C, Bernardini M et al. Arterial stiffness, intima-media thickness and carotid artery fibrosis in patients with primary aldosteronism. J Hypertens 2008; 26 (12): 2399\u20132405.","journal-title":"J Hypertens"},{"issue":"10","key":"BFjhh201370_CR25","doi-asserted-by":"publisher","first-page":"1086","DOI":"10.1038\/ajh.2008.243","volume":"21","author":"B Strauch","year":"2008","unstructured":"Strauch B, Petrak O, Zelinka T, Wichterle D, Holaj R, Kasalicky M et al. Adrenalectomy improves arterial stiffness in primary aldosteronism. Am J Hypertens 2008; 21 (10): 1086\u20131092.","journal-title":"Am J Hypertens"},{"issue":"4","key":"BFjhh201370_CR26","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1016\/S0735-1097(01)01504-2","volume":"38","author":"WJ Rogers","year":"2001","unstructured":"Rogers WJ, Hu YL, Coast D, Vido DA, Kramer CM, Pyeritz RE et al. Age-associated changes in regional aortic pulse wave velocity. J Am Coll Cardiol 2001; 38 (4): 1123\u20131129.","journal-title":"J Am Coll Cardiol"},{"issue":"3","key":"BFjhh201370_CR27","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1016\/j.jacc.2008.08.064","volume":"53","author":"A Rudolph","year":"2009","unstructured":"Rudolph A, Abdel-Aty H, Bohl S, Boye P, Zagrosek A, Dietz R et al. Noninvasive detection of fibrosis applying contrast-enhanced cardiac magnetic resonance in different forms of left ventricular hypertrophy relation to remodeling. J Am Coll Cardiol 2009; 53 (3): 284\u2013291.","journal-title":"J Am Coll Cardiol"},{"issue":"5","key":"BFjhh201370_CR28","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.1161\/HYPERTENSIONAHA.109.141531","volume":"55","author":"K Gaddam","year":"2010","unstructured":"Gaddam K, Corros C, Pimenta E, Ahmed M, Denney T, Aban I et al. Rapid reversal of left ventricular hypertrophy and intracardiac volume overload in patients with resistant hypertension and hyperaldosteronism: a prospective clinical study. Hypertension 2010; 55 (5): 1137\u20131142.","journal-title":"Hypertension"},{"issue":"4","key":"BFjhh201370_CR29","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1177\/1470320312446240","volume":"13","author":"T Indra","year":"2012","unstructured":"Indra T, Holaj R, Zelinka T, Petrak O, Strauch B, Rosa J et al. Left ventricle remodeling in men with moderate to severe volume-dependent hypertension. J Renin Angiotensin Aldosterone Syst 2012; 13 (4): 426\u2013434.","journal-title":"J Renin Angiotensin Aldosterone Syst"},{"issue":"10","key":"BFjhh201370_CR30","doi-asserted-by":"publisher","first-page":"2120","DOI":"10.1097\/HJH.0b013e32833d0177","volume":"28","author":"CB Stehr","year":"2010","unstructured":"Stehr CB, Mellado R, Ocaranza MP, Carvajal CA, Mosso L, Becerra E et al. Increased levels of oxidative stress, subclinical inflammation, and myocardial fibrosis markers in primary aldosteronism patients. J Hypertens 2010; 28 (10): 2120\u20132126.","journal-title":"J Hypertens"},{"key":"BFjhh201370_CR31","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/1532-429X-10-10","volume":"10","author":"MR Robinson","year":"2008","unstructured":"Robinson MR, Scheuermann-Freestone M, Leeson P, Channon KM, Clarke K, Neubauer S et al. Uncomplicated obesity is associated with abnormal aortic function assessed by cardiovascular magnetic resonance. J Cardiovasc Magn Reson 2008; 10: 10.","journal-title":"J Cardiovasc Magn Reson"},{"issue":"1","key":"BFjhh201370_CR32","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1161\/HYPERTENSIONAHA.109.134031","volume":"55","author":"RB Stacey","year":"2010","unstructured":"Stacey RB, Bertoni AG, Eng J, Bluemke DA, Hundley WG, Herrington D . Modification of the effect of glycemic status on aortic distensibility by age in the multi-ethnic study of atherosclerosis. Hypertension 2010; 55 (1): 26\u201332.","journal-title":"Hypertension"},{"issue":"8","key":"BFjhh201370_CR33","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1016\/j.jacc.2009.02.086","volume":"54","author":"OJ Rider","year":"2009","unstructured":"Rider OJ, Francis JM, Ali MK, Petersen SE, Robinson M, Robson MD et al. Beneficial cardiovascular effects of bariatric surgical and dietary weight loss in obesity. J Am Coll Cardiol 2009; 54 (8): 718\u2013726.","journal-title":"J Am Coll Cardiol"},{"issue":"6","key":"BFjhh201370_CR34","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1016\/j.jacc.2009.03.066","volume":"54","author":"NC Edwards","year":"2009","unstructured":"Edwards NC, Steeds RP, Stewart PM, Ferro CJ, Townend JN . Effect of spironolactone on left ventricular mass and aortic stiffness in early-stage chronic kidney disease: a randomized controlled trial. J Am Coll Cardiol 2009; 54 (6): 505\u2013512.","journal-title":"J Am Coll Cardiol"},{"issue":"6","key":"BFjhh201370_CR35","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1161\/CIRCIMAGING.112.974576","volume":"5","author":"EM Freel","year":"2012","unstructured":"Freel EM, Mark PB, Weir RA, McQuarrie EP, Allan K, Dargie HJ et al. Demonstration of blood pressure-independent noninfarct myocardial fibrosis in primary aldosteronism: a cardiac magnetic resonance imaging study. Circ Cardiovasc Imaging 2012; 5 (6): 740\u2013747.","journal-title":"Circ Cardiovasc Imaging"}],"container-title":["Journal of Human Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/jhh201370.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/jhh201370","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/jhh201370.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,17]],"date-time":"2022-03-17T15:05:41Z","timestamp":1647529541000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/jhh201370"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,25]]},"references-count":35,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["BFjhh201370"],"URL":"https:\/\/doi.org\/10.1038\/jhh.2013.70","relation":{},"ISSN":["0950-9240","1476-5527"],"issn-type":[{"value":"0950-9240","type":"print"},{"value":"1476-5527","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,25]]},"assertion":[{"value":"4 March 2013","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 May 2013","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 June 2013","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 July 2013","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}