{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T03:48:40Z","timestamp":1790394520724,"version":"4.1.0"},"reference-count":77,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,2]],"date-time":"2015-12-02T00:00:00Z","timestamp":1449014400000},"content-version":"vor","delay-in-days":2495,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2009,2]]},"DOI":"10.1038\/jid.2008.211","type":"journal-article","created":{"date-parts":[[2008,7,24]],"date-time":"2008-07-24T10:29:31Z","timestamp":1216895371000},"page":"392-405","source":"Crossref","is-referenced-by-count":97,"title":["Analysis of Cultured Human Melanocytes Based on Polymorphisms within the SLC45A2\/MATP, SLC24A5\/NCKX5, and OCA2\/P Loci"],"prefix":"10.1016","volume":"129","author":[{"given":"Anthony L.","family":"Cook","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy E.","family":"Thurber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren J.","family":"Smit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron G.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy G.","family":"Bladen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren L.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David L.","family":"Duffy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenza","family":"Pastorino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanna","family":"Bianchi-Scarra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Helen Leonard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer L.","family":"Stow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard A.","family":"Sturm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Part 4","key":"10.1038\/jid.2008.211_bb0010","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1242\/jcs.106.4.1323","article-title":"Contribution of melanogenic proteins to the heterogeneous pigmentation of human melanocytes","volume":"106","author":"Abdel-Malek","year":"1993","journal-title":"J Cell Sci"},{"key":"10.1038\/jid.2008.211_bb0015","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1111\/j.1600-0749.1994.tb00635.x","article-title":"Analysis of the UV-induced melanogenesis and growth arrest of human melanocytes","volume":"7","author":"Abdel-Malek","year":"1994","journal-title":"Pigment Cell Res"},{"key":"10.1038\/jid.2008.211_bb0020","doi-asserted-by":"crossref","first-page":"6930","DOI":"10.1128\/MCB.18.12.6930","article-title":"Targeting the microphthalmia basic helix-loop-helix-leucine zipper transcription factor to a subset of E-box elements in vitro and in vivo","volume":"18","author":"Aksan","year":"1998","journal-title":"Mol Cell Biol"},{"key":"10.1038\/jid.2008.211_bb0025","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1034\/j.1600-0749.2002.1o071.x","article-title":"Ethnic variation in melanin content and composition in photoexposed and photoprotected human skin","volume":"15","author":"Alaluf","year":"2002","journal-title":"Pigment Cell Res"},{"key":"10.1038\/jid.2008.211_bb0030","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0925-4773(02)00130-2","article-title":"The oculocutaneous albinism type IV gene Matp is a new marker of pigment cell precursors during mouse embryonic development","volume":"116","author":"Baxter","year":"2002","journal-title":"Mech Dev"},{"key":"10.1038\/jid.2008.211_bb0035","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1093\/hmg\/ddi219","article-title":"Altered cell surface expression of human MC1R variant receptor alleles associated with red hair and skin cancer risk","volume":"14","author":"Beaumont","year":"2005","journal-title":"Hum Mol Genet"},{"key":"10.1038\/jid.2008.211_bb0040","doi-asserted-by":"crossref","first-page":"E88","DOI":"10.1002\/humu.20788","article-title":"Red hair is the null phenotype of MC1R","volume":"29","author":"Beaumont","year":"2008","journal-title":"Human Mutat"},{"key":"10.1038\/jid.2008.211_bb0045","doi-asserted-by":"crossref","first-page":"6545","DOI":"10.1242\/dev.00872","article-title":"Mitf expression is sufficient to direct differentiation of medaka bluastula derived stem cells to melanocytes","volume":"130","author":"Bejar","year":"2003","journal-title":"Development"},{"key":"10.1038\/jid.2008.211_bb0050","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1034\/j.1600-0749.2003.00067.x","article-title":"The color loci of mice \u2013 a genetic century","volume":"16","author":"Bennett","year":"2003","journal-title":"Pigment Cell Res"},{"key":"10.1038\/jid.2008.211_bb0055","doi-asserted-by":"crossref","first-page":"2933","DOI":"10.1093\/bioinformatics\/bti473","article-title":"MatInspector and beyond: promoter analysis based on transcription factor binding sites","volume":"21","author":"Cartharius","year":"2005","journal-title":"Bioinformatics"},{"key":"10.1038\/jid.2008.211_bb0060","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1091\/mbc.02-02-0022.","article-title":"Pink-eyed dilution protein controls the processing of tyrosinase","volume":"13","author":"Chen","year":"2002","journal-title":"Mol Biol Cell"},{"key":"10.1038\/jid.2008.211_bb0065","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1046\/j.1600-0749.2003.00106.x","article-title":"Correction of defective early tyrosinase processing by bafilomycin A1 and monensin in pink-eyed dilution melanocytes","volume":"17","author":"Chen","year":"2004","journal-title":"Pigment Cell Res"},{"key":"10.1038\/jid.2008.211_bb0070","doi-asserted-by":"crossref","first-page":"10964","DOI":"10.1073\/pnas.0502856102","article-title":"Slc7a11 gene controls production of pheomelanin pigment and proliferation of cultured cells","volume":"102","author":"Chintala","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/jid.2008.211_bb0075","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1046\/j.1523-1747.2003.12562.x","article-title":"Human melanoblasts in culture: expression of BRN2 and synergistic regulation by fibroblast growth factor-2, stem cell factor, and endothelin-3","volume":"121","author":"Cook","year":"2003","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2008.211_bb0080","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.yexcr.2005.04.019","article-title":"Co-expression of SOX9 and SOX10 during melanocytic differentiation in vitro","volume":"308","author":"Cook","year":"2005","journal-title":"Exp Cell Res"},{"key":"10.1038\/jid.2008.211_bb0085","doi-asserted-by":"crossref","first-page":"3203","DOI":"10.1242\/jcs.00598","article-title":"Tyrosinase processing and intracellular trafficking is disrupted in mouse primary melanocytes carrying the underwhite (uw) mutation. A model for oculocutaneous albinism (OCA) type 4","volume":"116","author":"Costin","year":"2003","journal-title":"J Cell Sci"},{"key":"10.1038\/jid.2008.211_bb0090","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1021\/ac000912j","article-title":"Genotyping of two mutations in the HFE gene using single-base extension and high-performance liquid chromatography","volume":"73","author":"Devaney","year":"2001","journal-title":"Anal Chem"},{"key":"10.1038\/jid.2008.211_bb0095","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1074\/jbc.M110229200","article-title":"Identification of Aim-1 as the underwhite mouse mutant and its transcriptional regulation by MITF","volume":"277","author":"Du","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1038\/jid.2008.211_bb0100","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1093\/hmg\/ddh043","article-title":"Interactive effects of MC1R and OCA2 on melanoma risk phenotypes","volume":"13","author":"Duffy","year":"2004","journal-title":"Hum Mol Genet"},{"key":"10.1038\/jid.2008.211_bb0105","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1086\/510885","article-title":"A three-single-nucleotide polymorphism haplotype in intron 1 of OCA2 explains most human eye-color variation","volume":"80","author":"Duffy","year":"2007","journal-title":"Am J Hum Genet"},{"key":"10.1038\/jid.2008.211_bb0110","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/ng0195-92","article-title":"Autosomal recessive ocular albinism associated with a functionally significant tyrosinase gene polymorphism","volume":"9","author":"Fukai","year":"1995","journal-title":"Nat Genet"},{"key":"10.1038\/jid.2008.211_bb0115","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/ng584","article-title":"Mutations in the gene encoding B, a novel transporter protein, reduce melanin content in medaka","volume":"28","author":"Fukamachi","year":"2001","journal-title":"Nat Genet"},{"key":"10.1038\/jid.2008.211_bb0120","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1006\/excr.2000.5092","article-title":"Regulation of the catalytic activity of preexisting tyrosinase in black and Caucasian human melanocyte cell cultures","volume":"262","author":"Fuller","year":"2001","journal-title":"Exp Cell Res"},{"key":"10.1038\/jid.2008.211_bb0125","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1126\/science.257.5073.1121","article-title":"The mouse pink-eyed dilution gene: association with human Prader\u2013Willi and Angelman syndromes","volume":"257","author":"Gardner","year":"1992","journal-title":"Science"},{"key":"10.1038\/jid.2008.211_bb0130","doi-asserted-by":"crossref","first-page":"5486","DOI":"10.1074\/jbc.M707521200","article-title":"SLC24A5 encodes a trans-Golgi network protein with potassium-dependent sodium-calcium exchange activity that regulates human epidermal melanogenesis","volume":"283","author":"Ginger","year":"2008","journal-title":"J Biol Chem"},{"key":"10.1038\/jid.2008.211_bb0135","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0165-022X(00)00156-1","article-title":"Determination of SNP allele frequencies in pooled DNAs by primer extension genotyping and denaturing high-performance liquid chromatography","volume":"47","author":"Giordano","year":"2001","journal-title":"J Biochem Biophys Methods"},{"key":"10.1038\/jid.2008.211_bb0140","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1002\/humu.20143","article-title":"Single nucleotide polymorphisms in the MATP gene are associated with normal human pigmentation variation","volume":"25","author":"Graf","year":"2005","journal-title":"Hum Mutat"},{"key":"10.1038\/jid.2008.211_bb0145","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1002\/humu.20504","article-title":"Promoter polymorphisms in the MATP (SLC45A2) gene are associated with normal human skin color variation","volume":"28","author":"Graf","year":"2007","journal-title":"Hum Mutat"},{"key":"10.1038\/jid.2008.211_bb0150","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1534\/genetics.106.063107","article-title":"Mutations in SLC45A2 cause plumage color variation in chicken and Japanese quail","volume":"175","author":"Gunnarsson","year":"2007","journal-title":"Genetics"},{"key":"10.1038\/jid.2008.211_bb0155","doi-asserted-by":"crossref","first-page":"e1000074","DOI":"10.1371\/journal.pgen.1000074","article-title":"A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation","volume":"4","author":"Han","year":"2008","journal-title":"PLoS Genet"},{"key":"10.1038\/jid.2008.211_bb0160","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1002\/jcp.1041350213","article-title":"Growth characteristics of human epidermal melanocytes in pure culture with special reference to genetic differences","volume":"135","author":"Hirobe","year":"1988","journal-title":"J Cell Physiol"},{"key":"10.1038\/jid.2008.211_bb0165","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1034\/j.1600-0749.2003.00018.x","article-title":"Melanin has a role in Ca2+ homeostasis in human melanocytes","volume":"16","author":"Hoogduijn","year":"2003","journal-title":"Pigment Cell Res"},{"key":"10.1038\/jid.2008.211_bb0170","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1111\/j.1600-0749.1995.tb00664.x","article-title":"Eumelanin and phaeomelanin contents of human epidermis and cultured melanocytes","volume":"8","author":"Hunt","year":"1995","journal-title":"Pigment Cell Res"},{"key":"10.1038\/jid.2008.211_bb0175","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1111\/1523-1747.ep12476630","article-title":"Role of tyrosinase as the determinant of pigmentation in cultured human melanocytes","volume":"100","author":"Iozumi","year":"1993","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2008.211_bb0180","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/1523-1747.ep12872677","article-title":"The relationship between tyrosinase activity and skin color in human foreskins","volume":"95","author":"Iwata","year":"1990","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2008.211_bb0185","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1086\/377569","article-title":"MC1R mutations modify the classic phenotype of oculocutaneous albinism type 2 (OCA2)","volume":"73","author":"King","year":"2003","journal-title":"Am J Hum Genet"},{"key":"10.1038\/jid.2008.211_bb0190","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1126\/science.1116238","article-title":"SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans","volume":"310","author":"Lamason","year":"2005","journal-title":"Science"},{"key":"10.1038\/jid.2008.211_bb0195","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1046\/j.1523-1747.2000.00107.x","article-title":"The underwhite (uw) locus acts autonomously and reduces the production of melanin","volume":"115","author":"Lehman","year":"2000","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2008.211_bb0200","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1034\/j.1600-0749.2003.00033.x","article-title":"Screening of human primary melanocytes of defined melanocortin-1 receptor genotype: pigmentation marker, ultrastructural and UV-survival studies","volume":"16","author":"Leonard","year":"2003","journal-title":"Pigment Cell Res"},{"key":"10.1038\/jid.2008.211_bb0205","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1186\/1297-9686-35-1-119","article-title":"A mutation in the MATP gene causes the cream coat colour in the horse","volume":"35","author":"Mariat","year":"2003","journal-title":"Genet Sel Evol"},{"key":"10.1038\/jid.2008.211_bb0210","doi-asserted-by":"crossref","first-page":"R176","DOI":"10.1093\/hmg\/ddl217","article-title":"The genetic architecture of normal variation in human pigmentation: an evolutionary perspective and model","volume":"15","author":"McEvoy","year":"2006","journal-title":"Hum Mol Genet"},{"key":"10.1038\/jid.2008.211_bb0215","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.1365-2133.1991.tb14161.x","article-title":"Pigment content of cultured human melanocytes does not correlate with tyrosinase message level","volume":"125","author":"Naeyaert","year":"1991","journal-title":"Br J Dermatol"},{"key":"10.1038\/jid.2008.211_bb0220","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1007\/s100380200007","article-title":"Distinctive distribution of AIM1 polymorphism among major human populations with different skin color","volume":"47","author":"Nakayama","year":"2002","journal-title":"J Hum Genet"},{"key":"10.1038\/jid.2008.211_bb0225","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1086\/324340","article-title":"Mutations in the human orthologue of the mouse underwhite gene (uw) underlie a new form of oculocutaneous albinism, OCA4","volume":"69","author":"Newton","year":"2001","journal-title":"Am J Hum Genet"},{"key":"10.1038\/jid.2008.211_bb0230","doi-asserted-by":"crossref","first-page":"2216","DOI":"10.1038\/sj.jid.5700840","article-title":"Post-transcriptional regulation of melanin biosynthetic enzymes by cAMP and resveratrol in human melanocytes","volume":"127","author":"Newton","year":"2007","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2008.211_bb0235","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.1016\/j.peptides.2007.10.003","article-title":"Human melanocytes expressing MC1R variant alleles show impaired activation of multiple signaling pathways","volume":"28","author":"Newton","year":"2007","journal-title":"Peptides"},{"key":"10.1038\/jid.2008.211_bb0240","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1093\/molbev\/msl203","article-title":"Genetic evidence for the convergent evolution of light skin in Europeans and East Asians","volume":"24","author":"Norton","year":"2007","journal-title":"Mol Biol Evol"},{"key":"10.1038\/jid.2008.211_bb0245","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1086\/302711","article-title":"Melanocortin-1 receptor polymorphisms and risk of melanoma: is the association explained solely by pigmentation phenotype?","volume":"66","author":"Palmer","year":"2000","journal-title":"Am J Hum Genet"},{"key":"10.1038\/jid.2008.211_bb0250","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1002\/humu.9253","article-title":"Novel MC1R variants in Ligurian melanoma patients and controls","volume":"24","author":"Pastorino","year":"2004","journal-title":"Hum Mutat"},{"key":"10.1038\/jid.2008.211_bb0255","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.1093\/hmg\/9.19.2845","article-title":"The Menkes copper transporter is required for the activation of tyrosinase","volume":"9","author":"Petris","year":"2000","journal-title":"Hum Mol Genet"},{"key":"10.1038\/jid.2008.211_bb0260","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1365-2133.2006.07376.x","article-title":"Oral zinc sulphate causes murine hair hypopigmentation and is a potent inhibitor of eumelanogenesis in vivo","volume":"155","author":"Plonka","year":"2006","journal-title":"Br J Dermatol"},{"key":"10.1038\/jid.2008.211_bb0265","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1111\/j.1600-0749.1995.tb00657.x","article-title":"Comparative analysis of melanins and melanosomes produced by various coat color mutants","volume":"8","author":"Prota","year":"1995","journal-title":"Pigment Cell Res"},{"key":"10.1038\/jid.2008.211_bb0270","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1038\/ng1700","article-title":"Genetic analysis of cavefish reveals molecular convergence in the evolution of albinism","volume":"38","author":"Protas","year":"2006","journal-title":"Nat Genet"},{"key":"10.1038\/jid.2008.211_bb0275","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/0092-8674(81)90383-4","article-title":"All classes of intermediate filaments share a common antigenic determinant defined by a monoclonal antibody","volume":"27","author":"Pruss","year":"1981","journal-title":"Cell"},{"key":"10.1038\/jid.2008.211_bb0280","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1046\/j.1523-1747.2000.00108.x","article-title":"Aberrant pH of melanosomes in pink-eyed dilution (p) mutant melanocytes","volume":"115","author":"Puri","year":"2000","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2008.211_bb0285","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1038\/361072a0","article-title":"A gene for the mouse pink-eyed dilution locus and for human type II oculocutaneous albinism","volume":"361","author":"Rinchik","year":"1993","journal-title":"Nature"},{"key":"10.1038\/jid.2008.211_bb0290","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1002\/jcp.21318","article-title":"Melanocytes expressing MC1R polymorphisms associated with red hair color have altered MSH-ligand activated pigmentary responses in coculture with keratinocytes","volume":"215","author":"Roberts","year":"2008","journal-title":"J Cell Physiol"},{"key":"10.1038\/jid.2008.211_bb0295","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1007\/s00424-003-1069-0","article-title":"The SLC24 Na+\/Ca2+-K+ exchanger family: vision and beyond","volume":"447","author":"Schnetkamp","year":"2004","journal-title":"Pflugers Arch"},{"key":"10.1038\/jid.2008.211_bb0300","doi-asserted-by":"crossref","first-page":"6413","DOI":"10.1046\/j.1432-1327.2000.01737.x","article-title":"Domains of Brn-2 that mediate homodimerization and interaction with general and melanocytic transcription factors","volume":"267","author":"Smit","year":"2000","journal-title":"Eur J Biochem"},{"key":"10.1038\/jid.2008.211_bb0305","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1007\/s004030050315","article-title":"Variations in melanin formation by cultured melanocytes from different skin types","volume":"290","author":"Smit","year":"1998","journal-title":"Arch Dermatol Res"},{"key":"10.1038\/jid.2008.211_bb0310","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.yexcr.2004.04.033","article-title":"The relationship between Na(+)\/H(+) exchanger expression and tyrosinase activity in human melanocytes","volume":"298","author":"Smith","year":"2004","journal-title":"Exp Cell Res"},{"key":"10.1038\/jid.2008.211_bb0315","doi-asserted-by":"crossref","first-page":"4206","DOI":"10.1091\/mbc.E02-05-0282","article-title":"Pink-eyed dilution protein modulates arsenic sensitivity and intracellular glutathione metabolism","volume":"13","author":"Staleva","year":"2002","journal-title":"Mol Biol Cell"},{"key":"10.1038\/jid.2008.211_bb0320","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1086\/522235","article-title":"A genomewide association study of skin pigmentation in a south Asian population","volume":"81","author":"Stokowski","year":"2007","journal-title":"Am J Hum Genet"},{"key":"10.1038\/jid.2008.211_bb0325","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.tig.2006.06.010","article-title":"A golden age of human pigmentation genetics","volume":"22","author":"Sturm","year":"2006","journal-title":"Trends Genet"},{"key":"10.1038\/jid.2008.211_bb0330","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.ajhg.2007.11.005","article-title":"A single SNP in an evolutionary conserved region within Intron 86 of the HERC2 gene determines human blue-brown eye colour","volume":"82","author":"Sturm","year":"2008","journal-title":"Am J Hum Genet"},{"key":"10.1038\/jid.2008.211_bb0335","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.tig.2004.06.010","article-title":"Eye colour: portals into pigmentation genes and ancestry","volume":"20","author":"Sturm","year":"2004","journal-title":"Trends Genet"},{"key":"10.1038\/jid.2008.211_bb0340","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1038\/ng.160","article-title":"Two newly identified genetic determinants of pigmentation in Europeans","volume":"40","author":"Sulem","year":"2008","journal-title":"Nat Genet"},{"key":"10.1038\/jid.2008.211_bb0345","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1038\/ng.2007.13","article-title":"Genetic determinants of hair, eye and skin pigmentation in Europeans","volume":"39","author":"Sulem","year":"2007","journal-title":"Nat Genet"},{"key":"10.1038\/jid.2008.211_bb0350","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1046\/j.1523-1747.2002.01647.x","article-title":"Increase of pro-opiomelanocortin mRNA prior to tyrosinase, tyrosinase-related protein 1, dopachrome tautomerase, Pmel-17\/gp100, and P-protein mRNA in human skin after ultraviolet B irradiation","volume":"118","author":"Suzuki","year":"2002","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2008.211_bb0355","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1096\/fj.02-0865fje","article-title":"UV-induced DNA damage and melanin content in human skin differing in racial\/ethnic origin","volume":"17","author":"Tadokoro","year":"2003","journal-title":"FASEB J"},{"key":"10.1038\/jid.2008.211_bb0360","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1111\/j.0022-202X.2005.23760.x","article-title":"Mechanisms of skin tanning in different racial\/ethnic groups in response to ultraviolet radiation","volume":"124","author":"Tadokoro","year":"2005","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2008.211_bb0365","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1111\/1523-1747.ep12476615","article-title":"Differential regulation of tyrosinase activity in skin of white and black individuals in vivo by topical retinoic acid","volume":"100","author":"Talwar","year":"1993","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2008.211_bb0370","first-page":"691","article-title":"The brn-2 gene regulates the melanocytic phenotype and tumorigenic potential of human melanoma cells","volume":"11","author":"Thomson","year":"1995","journal-title":"Oncogene"},{"key":"10.1038\/jid.2008.211_bb0375","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1034\/j.1600-0749.2002.02007.x","article-title":"The etiology of oculocutaneous albinism (OCA) type II: the pink protein modulates the processing and transport of tyrosinase","volume":"15","author":"Toyofuku","year":"2002","journal-title":"Pigment Cell Res"},{"key":"10.1038\/jid.2008.211_bb0380","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1755-148X.2007.00415.x","article-title":"Characterisation of melanin in human iridal and choridal melanocytes from eyes with various colored irides","volume":"21","author":"Wakamatsu","year":"2008","journal-title":"Pigment Cell Melanoma Res"},{"key":"10.1038\/jid.2008.211_bb0385","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/j.1600-0749.2006.00293.x","article-title":"Diversity of pigmentation in cultured human melanocytes is due to differences in the type as well as quantity of melanin","volume":"19","author":"Wakamatsu","year":"2006","journal-title":"Pigment Cell Res"},{"key":"10.1038\/jid.2008.211_bb0390","doi-asserted-by":"crossref","first-page":"7971","DOI":"10.1074\/jbc.M309714200","article-title":"Regulation of tyrosinase processing and trafficking by organellar pH and by proteasome activity","volume":"279","author":"Watabe","year":"2004","journal-title":"J Biol Chem"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X15341890?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X15341890?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,9,13]],"date-time":"2021-09-13T19:40:12Z","timestamp":1631562012000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X15341890"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2]]},"references-count":77,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["S0022202X15341890"],"URL":"https:\/\/doi.org\/10.1038\/jid.2008.211","relation":{},"ISSN":["0022-202X"],"issn-type":[{"value":"0022-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2009,2]]}}}