{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,6]],"date-time":"2025-04-06T18:10:04Z","timestamp":1743963004579,"version":"3.40.3"},"reference-count":39,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2015,12,2]],"date-time":"2015-12-02T00:00:00Z","timestamp":1449014400000},"content-version":"vor","delay-in-days":1765,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["jidonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2011,2]]},"DOI":"10.1038\/jid.2010.308","type":"journal-article","created":{"date-parts":[[2010,10,28]],"date-time":"2010-10-28T08:39:33Z","timestamp":1288255173000},"page":"435-442","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Irritant Activation of Epithelial Cells Is Mediated via Protease-Dependent EGFR Activation"],"prefix":"10.1016","volume":"131","author":[{"given":"Kellie J.","family":"White","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent J.","family":"Maffei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marvin","family":"Newton-West","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert A.","family":"Swerlick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1038\/jid.2010.308_bb0010","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1007\/s00109-004-0545-0","article-title":"The zinc finger transcription factor egr-1 is upregulated in arsenite-treated human keratinocytes","volume":"82","author":"Al-Sarraj","year":"2004","journal-title":"J Mol Med"},{"key":"10.1038\/jid.2010.308_bb0015","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/sj.jid.5700557","article-title":"Optimized methodology for sequential extraction of RNA and protein from small human skin biopsies","volume":"127","author":"Berglund","year":"2007","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2010.308_bb0020","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1038\/nrm1548","article-title":"ADAMs: key components in EGFR signalling and development","volume":"6","author":"Blobel","year":"2005","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1038\/jid.2010.308_bb0025","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1083\/jcb.106.3.761","article-title":"Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line","volume":"106","author":"Boukamp","year":"1988","journal-title":"J Cell Biol"},{"key":"10.1038\/jid.2010.308_bb0030","doi-asserted-by":"crossref","first-page":"2286","DOI":"10.1172\/JCI119766","article-title":"Transgenic expression of the human amphiregulin gene induces a psoriasis-like phenotype","volume":"100","author":"Cook","year":"1997","journal-title":"J Clin Invest"},{"key":"10.1038\/jid.2010.308_bb0035","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1111\/j.1365-2133.2005.06989.x","article-title":"Variation in barrier impairment and inflammation of human skin as determined by sodium lauryl sulphate penetration rate","volume":"154","author":"de Jongh","year":"2006","journal-title":"Br J Dermatol"},{"key":"10.1038\/jid.2010.308_bb0040","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1111\/j.0105-1873.2006.00848.x","article-title":"Stratum corneum cytokines and skin irritation response to sodium lauryl sulfate","volume":"54","author":"de Jongh","year":"2006","journal-title":"Contact Derm"},{"key":"10.1038\/jid.2010.308_bb0045","doi-asserted-by":"crossref","first-page":"283","DOI":"10.2165\/00128071-200203040-00006","article-title":"Importance of irritant contact dermatitis in occupational skin disease","volume":"3","author":"Dickel","year":"2002","journal-title":"Am J Clin Dermatol"},{"key":"10.1038\/jid.2010.308_bb0050","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1146\/annurev.immunol.20.091301.131133","article-title":"MAP kinases in the immune response","volume":"20","author":"Dong","year":"2002","journal-title":"Annu Rev Immunol"},{"key":"10.1038\/jid.2010.308_bb0055","doi-asserted-by":"crossref","first-page":"470","DOI":"10.2144\/19962003470","article-title":"Quantitative RT-PCR on CYP1A1 heterogeneous nuclear RNA: a surrogate for the in vitro transcription run-on assay","volume":"20","author":"Elferink","year":"1996","journal-title":"Biotechniques"},{"key":"10.1038\/jid.2010.308_bb0060","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1136\/oem.2003.010710","article-title":"Current concepts of irritant contact dermatitis","volume":"61","author":"English","year":"2004","journal-title":"Occup Environ Med"},{"key":"10.1038\/jid.2010.308_bb0065","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1111\/j.1600-0536.1994.tb00648.x","article-title":"Sodium lauryl sulphate penetration in an in vitro model using human skin","volume":"30","author":"Fullerton","year":"1994","journal-title":"Contact Derm"},{"key":"10.1038\/jid.2010.308_bb0070","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1038\/jid.2008.269","article-title":"Iron chelators and hypoxia mimetics inhibit IFNgamma-mediated Jak-STAT signaling","volume":"129","author":"Gira","year":"2009","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2010.308_bb0075","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1111\/j.1600-0536.1996.tb02416.x","article-title":"Different pathways in irritant contact eczema? Early differences in the epidermal elemental content and expression of cytokines after application of 2 different irritants","volume":"35","author":"Grangsjo","year":"1996","journal-title":"Contact Derm"},{"key":"10.1038\/jid.2010.308_bb0080","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1600-0536.1995.tb00438.x","article-title":"The sodium lauryl sulfate model: an overview","volume":"33","author":"Lee","year":"1995","journal-title":"Contact Derm"},{"key":"10.1038\/jid.2010.308_bb0085","series-title":"Irritant Dermatitis","first-page":"257","article-title":"Sodium lauryl sulfate","author":"Lee","year":"2006"},{"key":"10.1038\/jid.2010.308_bb0090","doi-asserted-by":"crossref","first-page":"2915","DOI":"10.1038\/sj.onc.1201834","article-title":"Stress-induced immediate-early gene, egr-1, involves activation of p38\/JNK1","volume":"16","author":"Lim","year":"1998","journal-title":"Oncogene"},{"key":"10.1038\/jid.2010.308_bb0095","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1034\/j.1600-0536.2003.480105.x","article-title":"Profile of irritant patch testing with detergents: sodium lauryl sulfate, sodium laureth sulfate and alkyl polyglucoside","volume":"48","author":"Loffler","year":"2003","journal-title":"Contact Derm"},{"key":"10.1038\/jid.2010.308_bb0100","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S0002-9440(10)63654-1","article-title":"Blockade of the EGF receptor induces a deranged chemokine expression in keratinocytes leading to enhanced skin inflammation","volume":"163","author":"Mascia","year":"2003","journal-title":"Am J Pathol"},{"key":"10.1038\/jid.2010.308_bb0105","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1038\/nm0402-358","article-title":"CD39 is the dominant Langerhans cell-associated ecto-NTPDase: modulatory roles in inflammation and immune responsiveness","volume":"8","author":"Mizumoto","year":"2002","journal-title":"Nat Med"},{"key":"10.1038\/jid.2010.308_bb0110","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1046\/j.1523-1747.2003.12558.x","article-title":"Keratinocyte ATP release assay for testing skin-irritating potentials of structurally diverse chemicals","volume":"121","author":"Mizumoto","year":"2003","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2010.308_bb0115","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1034\/j.1600-0536.2001.044004240.x","article-title":"Pathological findings in cumulative irritation induced by SLS and croton oil in hairless mice","volume":"44","author":"Moon","year":"2001","journal-title":"Contact Derm"},{"key":"10.1038\/jid.2010.308_bb0120","series-title":"Cutaneous Medicine and Surgery: An Integrated Program in Dermatology","first-page":"173","article-title":"Contact dermatitis and cccupational dermatology","author":"Nethercott","year":"1996"},{"key":"10.1038\/jid.2010.308_bb0125","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1046\/j.1523-1747.2000.00056.x","article-title":"Cytokine release and cytotoxicity in human keratinocytes and fibroblasts induced by phenols and sodium dodecyl sulfate","volume":"115","author":"Newby","year":"2000","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2010.308_bb0130","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1046\/j.1523-1747.2003.12063.x","article-title":"Regulation of tissue factor in microvascular dermal endothelial cells","volume":"120","author":"O'Reilly","year":"2003","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2010.308_bb0135","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1111\/j.1365-2133.1997.tb03783.x","article-title":"Contact allergens and sodium lauryl sulfate upregulate vascular endothelial growth factor in normal keratinocytes","volume":"137","author":"Palacio","year":"1997","journal-title":"Br J Dermatol"},{"key":"10.1038\/jid.2010.308_bb0140","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1038\/sj.jid.5701184","article-title":"The epidermal growth factor receptor system in skin repair and inflammation","volume":"128","author":"Pastore","year":"2008","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2010.308_bb0145","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1002\/jps.2600841018","article-title":"Quantification of sodium lauryl sulfate penetration into the skin and underlying tissue after topical application\u2014pharmacological and toxicological implications","volume":"84","author":"Patil","year":"1995","journal-title":"J Pharm Sci"},{"key":"10.1038\/jid.2010.308_bb0150","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1007\/s00403-009-0946-6","article-title":"Skin barrier disruption by acetone: observations in a hairless mouse skin model","volume":"301","author":"Rissmann","year":"2009","journal-title":"Arch Dermatol Res"},{"key":"10.1038\/jid.2010.308_bb0155","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1080\/08977190600634373","article-title":"Control of ErbB signaling through metalloprotease mediated ectodomain shedding of EGF-like factors","volume":"24","author":"Sanderson","year":"2006","journal-title":"Growth Factors"},{"key":"10.1038\/jid.2010.308_bb0160","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1471-2199-7-3","article-title":"The RIN: an RNA integrity number for assigning integrity values to RNA measurements","volume":"7","author":"Schroeder","year":"2006","journal-title":"BMC Mol Biol"},{"key":"10.1038\/jid.2010.308_bb0165","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1002\/jcp.10178","article-title":"Regulation of life and death by the zinc finger transcription factor Egr-1","volume":"193","author":"Thiel","year":"2002","journal-title":"J Cell Physiol"},{"key":"10.1038\/jid.2010.308_bb0170","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.tiv.2005.09.011","article-title":"Variations in the mRNA expression of inflammatory mediators, markers of differentiation and lipid-metabolizing enzymes caused by sodium lauryl sulphate in cultured human keratinocytes","volume":"20","author":"Torma","year":"2006","journal-title":"Toxicol In Vitro"},{"key":"10.1038\/jid.2010.308_bb0175","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/S0014-4827(03)00002-8","article-title":"Trafficking of the ErbB receptors and its influence on signaling","volume":"284","author":"Wiley","year":"2003","journal-title":"Exp Cell Res"},{"key":"10.1038\/jid.2010.308_bb0180","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1111\/1523-1747.ep12383512","article-title":"Cytokine induction in human epidermal keratinocytes exposed to contact irritants and its relation to chemical-induced inflammation in mouse skin","volume":"102","author":"Wilmer","year":"1994","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2010.308_bb0185","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1111\/1523-1747.ep12343392","article-title":"Barrier disruption stimulates interleukin-1 alpha expression and release from a pre-formed pool in murine epidermis","volume":"106","author":"Wood","year":"1996","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2010.308_bb0190","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1172\/JCI115884","article-title":"Cutaneous barrier perturbation stimulates cytokine production in the epidermis of mice","volume":"90","author":"Wood","year":"1992","journal-title":"J Clin Invest"},{"key":"10.1038\/jid.2010.308_bb0195","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1038\/35052073","article-title":"Untangling the ErbB signalling network","volume":"2","author":"Yarden","year":"2001","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1038\/jid.2010.308_bb0200","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1242\/jcs.03389","article-title":"Wound-induced ATP release and EGF receptor activation in epithelial cells","volume":"120","author":"Yin","year":"2007","journal-title":"J Cell Sci"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X15351265?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X15351265?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,6]],"date-time":"2025-04-06T17:29:50Z","timestamp":1743960590000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X15351265"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,2]]}},"alternative-id":["S0022202X15351265"],"URL":"https:\/\/doi.org\/10.1038\/jid.2010.308","relation":{},"ISSN":["0022-202X"],"issn-type":[{"type":"print","value":"0022-202X"}],"subject":[],"published":{"date-parts":[[2011,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Irritant Activation of Epithelial Cells Is Mediated via Protease-Dependent EGFR Activation","name":"articletitle","label":"Article Title"},{"value":"Journal of Investigative Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/jid.2010.308","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 The Society for Investigative Dermatology, Inc. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}