{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T17:02:18Z","timestamp":1776704538977,"version":"3.51.2"},"reference-count":19,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2015,12,2]],"date-time":"2015-12-02T00:00:00Z","timestamp":1449014400000},"content-version":"vor","delay-in-days":2041,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["jidonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2010,5]]},"DOI":"10.1038\/jid.2010.52","type":"journal-article","created":{"date-parts":[[2010,4,15]],"date-time":"2010-04-15T07:47:39Z","timestamp":1271317659000},"page":"1205-1207","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"title":["Lipids to the Top of Hair Biology"],"prefix":"10.1016","volume":"130","author":[{"given":"Kurt S.","family":"Stenn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pratima","family":"Karnik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1038\/jid.2010.52_bb0010","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.cell.2009.09.006","article-title":"Structural ties between cholesterol transport and morphogen signaling","volume":"138","author":"Bazan","year":"2009","journal-title":"Cell"},{"key":"10.1038\/jid.2010.52_bb0015","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/nature07202","article-title":"Integration of metabolism and inflammation by lipid-activated nuclear receptors","volume":"454","author":"Bensinger","year":"2008","journal-title":"Nature"},{"key":"10.1038\/jid.2010.52_bb0020","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1016\/j.biocel.2007.05.002","article-title":"Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2","volume":"39","author":"Colgan","year":"2007","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1038\/jid.2010.52_bb0025","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1242\/dev.030700","article-title":"Notch signaling in bulge stem cells is not required for selection of hair follicle fate","volume":"136","author":"Demehri","year":"2009","journal-title":"Development"},{"key":"10.1038\/jid.2010.52_bb0030","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1038\/jid.2009.442","article-title":"Hair growth defects in Insig-deficient mice caused by cholesterol precursor accumulation and reversed by simvastatin","volume":"130","author":"Evers","year":"2010","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2010.52_bb0035","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1038\/nature05485","article-title":"Inflammation and metabolic disorders","volume":"444","author":"Hotamisligil","year":"2006","journal-title":"Nature"},{"key":"10.1038\/jid.2010.52_bb0040","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1038\/jid.2008.369","article-title":"Hair follicle stem cell-specific PPAR\u03b3 deletion causes scarring alopecia","volume":"129","author":"Karnik","year":"2009","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2010.52_bb0045","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1038\/sj.jid.5700511","article-title":"Loss of the acyl-CoA binding protein (Acbp) results in fatty acid metabolism abnormalities in mouse hair and skin","volume":"127","author":"Lee","year":"2007","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2010.52_bb0050","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/S0092-8674(01)00369-5","article-title":"Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1","volume":"105","author":"Lewis","year":"2001","journal-title":"Cell"},{"key":"10.1038\/jid.2010.52_bb0055","doi-asserted-by":"crossref","first-page":"5274","DOI":"10.1073\/pnas.0431186100","article-title":"Cloning of wrinkle-free, a previously uncharacterized mouse mutation, reveals crucial roles for fatty acid transport protein 4 in skin and hair development","volume":"100","author":"Moulson","year":"2003","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/jid.2010.52_bb0060","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.bbalip.2008.07.004","article-title":"Lipid droplet\u2013organelle interactions; sharing the fats","volume":"1791","author":"Murphy","year":"2009","journal-title":"Biochim Biophys Acta Mol Cell Biol Lipids"},{"key":"10.1038\/jid.2010.52_bb0065","doi-asserted-by":"crossref","first-page":"5297","DOI":"10.1242\/dev.00821","article-title":"Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface","volume":"130","author":"Nusse","year":"2003","journal-title":"Development"},{"key":"10.1038\/jid.2010.52_bb0070","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1038\/nrm2199","article-title":"Signal integration in the endoplasmic reticulum unfolded protein response","volume":"8","author":"Ron","year":"2007","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1038\/jid.2010.52_bb0075","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1038\/jid.2008.290","article-title":"Mutations in the lipase H gene underlie autosomal recessive woolly hair\/hypotrichosis","volume":"129","author":"Shimomura","year":"2009","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2010.52_bb0080","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1016\/S0002-9440(10)65078-X","article-title":"Asebia-2J (Scd1ab2J): a new allele and a model for scarring alopecia","volume":"156","author":"Sundberg","year":"2000","journal-title":"Am J Pathol"},{"key":"10.1038\/jid.2010.52_bb0085","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1038\/nri2359","article-title":"The endoplasmic reticulum stress response in immunity and autoimmunity","volume":"8","author":"Todd","year":"2008","journal-title":"Nat Rev Immunol"},{"key":"10.1038\/jid.2010.52_bb0090","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1101\/gad.1567207","article-title":"Maternal PPAR\u03b3 protects nursing neonates by suppressing the production of inflammatory milk","volume":"21","author":"Wan","year":"2007","journal-title":"Genes Dev"},{"key":"10.1038\/jid.2010.52_bb0095","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.cell.2007.02.049","article-title":"Coordinated regulation of nutrient and inflammatory responses by STAMP2 is essential for metabolic homeostasis","volume":"129","author":"Wellen","year":"2007","journal-title":"Cell"},{"key":"10.1038\/jid.2010.52_bb0100","doi-asserted-by":"crossref","first-page":"5621","DOI":"10.1074\/jbc.M310529200","article-title":"Role for ELOVL3 and fatty acid chain length in development of hair and skin function","volume":"279","author":"Westerberg","year":"2004","journal-title":"J Biol Chem"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X15348041?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X15348041?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,6]],"date-time":"2025-04-06T12:55:00Z","timestamp":1743944100000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X15348041"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,5]]}},"alternative-id":["S0022202X15348041"],"URL":"https:\/\/doi.org\/10.1038\/jid.2010.52","relation":{},"ISSN":["0022-202X"],"issn-type":[{"value":"0022-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2010,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lipids to the Top of Hair Biology","name":"articletitle","label":"Article Title"},{"value":"Journal of Investigative Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/jid.2010.52","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 The Society for Investigative Dermatology, Inc. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}