{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T01:40:31Z","timestamp":1791855631994,"version":"4.3.4"},"reference-count":30,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2015,12,2]],"date-time":"2015-12-02T00:00:00Z","timestamp":1449014400000},"content-version":"vor","delay-in-days":945,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["jidonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1038\/jid.2012.510","type":"journal-article","created":{"date-parts":[[2013,2,7]],"date-time":"2013-02-07T09:23:51Z","timestamp":1360229031000},"page":"1197-1204","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":397,"title":["Comprehensive Survival Analysis of a Cohort of Patients with Stevens\u2013Johnson Syndrome and Toxic Epidermal Necrolysis"],"prefix":"10.1016","volume":"133","author":[{"given":"Peggy","family":"Sekula","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariane","family":"Dunant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maja","family":"Mockenhaupt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Naldi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan Nico","family":"Bouwes Bavinck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sima","family":"Halevy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvia","family":"Kardaun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexis","family":"Sidoroff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvonne","family":"Liss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Schumacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Claude","family":"Roujeau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/jid.2012.510_bb0010","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1046\/j.1523-1747.2000.00061.x","article-title":"SCORTEN: A severity-of-illness score for toxic epidermal necrolysis","volume":"115","author":"Bastuji-Garin","year":"2000","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2012.510_bb0015","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1001\/archderm.1993.01680220104023","article-title":"Clinical classification of cases of toxic epidermal necrolysis, Stevens-Johnson syndrome, and erythema multiforme","volume":"129","author":"Bastuji-Garin","year":"1993","journal-title":"Arch Dermatol"},{"key":"10.1038\/jid.2012.510_bb0020","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1093\/ageing\/22.6.450","article-title":"Toxic epidermal necrolysis (Lyell syndrome) in 77 elderly patients","volume":"22","author":"Bastuji-Garin","year":"1993","journal-title":"Age Ageing"},{"key":"10.1038\/jid.2012.510_bb0025","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/S0140-6736(10)60274-7","article-title":"Acute liver failure","volume":"376","author":"Bernal","year":"2010","journal-title":"Lancet"},{"key":"10.1038\/jid.2012.510_bb0030","first-page":"76.1","article-title":"Erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis","volume":"76","author":"Breathnach","year":"2010"},{"key":"10.1038\/jid.2012.510_bb0035","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/S0140-6736(02)08272-7","article-title":"Quantification of the completeness of follow-up","volume":"359","author":"Clark","year":"2002","journal-title":"Lancet"},{"key":"10.1038\/jid.2012.510_bb0040","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1097\/PRS.0b013e3181773d5d","article-title":"Antishear therapy for toxic epidermal necrolysis: An alternative treatment approach","volume":"122","author":"Dorafshar","year":"2008","journal-title":"Plast Reconstr Surg"},{"key":"10.1038\/jid.2012.510_bb0045","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1097\/BCR.0b013e3181848bb1","article-title":"Toxic epidermal necrolysis clinical guidelines","volume":"29","author":"Endorf","year":"2008","journal-title":"J Burn Care Res"},{"key":"10.1038\/jid.2012.510_bb0050","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1001\/archderm.136.3.323","article-title":"Toxic epidermal necrolysis and Stevens-Johnson syndrome: does early withdrawal of causative drugs decrease the risk of death?","volume":"136","author":"Garcia-Doval","year":"2000","journal-title":"Arch Dermatol"},{"key":"10.1038\/jid.2012.510_bb0055","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/1750-1172-6-52","article-title":"Genome-wide association study of Stevens-Johnson syndrome and toxic epidermal necrolysis in Europe","volume":"6","author":"Genin","year":"2011","journal-title":"Orphanet J Rare Dis"},{"key":"10.1038\/jid.2012.510_bb0060","first-page":"269","article-title":"Toxic epidermal necrolysis and Stevens-Johnson syndrome in oncologic patients","volume":"11","author":"Gravante","year":"2007","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.1038\/jid.2012.510_bb0065","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1097\/01.BCR.0000150215.78220.79","article-title":"Late outcomes in adult survivors of toxic epidermal necrolysis after treatment in a burn center","volume":"26","author":"Haber","year":"2005","journal-title":"J Burn Care Rehabil"},{"key":"10.1038\/jid.2012.510_bb0070","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1111\/j.1365-2222.2004.01882.x","article-title":"Incidence of anaphylaxis with circulatory symptoms: a study over a 3-year period comprising 940,000 inhabitants of the Swiss Canton Bern","volume":"34","author":"Helbling","year":"2004","journal-title":"Clin Exp Allergy"},{"key":"10.1038\/jid.2012.510_bb0075","series-title":"Survival analysis: Techniques for Censored and Truncated Data","first-page":"536","author":"Klein","year":"2005"},{"key":"10.1038\/jid.2012.510_bb0080","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1097\/00003246-198510000-00009","article-title":"APACHE II: a severity of disease classification system","volume":"13","author":"Knaus","year":"1985","journal-title":"Crit Care Med"},{"key":"10.1038\/jid.2012.510_bb0085","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.burns.2009.06.213","article-title":"Toxic epidermal necrolysis (Lyell\u2019s disease)","volume":"36","author":"Lissia","year":"2010","journal-title":"Burns"},{"key":"10.1038\/jid.2012.510_bb0090","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1097\/00006534-199809020-00014","article-title":"Toxic epidermal necrolysis syndrome: mortality rate reduced with early referral to regional burn center","volume":"102","author":"McGee","year":"1998","journal-title":"Plast Reconstr Surg"},{"key":"10.1038\/jid.2012.510_bb0095","series-title":"Braun-Falco\u2019s Dermatology","first-page":"473","article-title":"Severe cutaneous adverse reactions","author":"Mockenhaupt","year":"2009"},{"key":"10.1038\/jid.2012.510_bb0100","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1001\/archderm.1990.01670320127028","article-title":"Incidence of toxic epidermal necrolysis in Italy","volume":"126","author":"Naldi","year":"1990","journal-title":"Arch Dermatol"},{"key":"10.1038\/jid.2012.510_bb0105","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1097\/01.bcr.0000194268.01514.f8","article-title":"Long-term follow-up of patients treated for toxic epidermal necrolysis","volume":"1","author":"Oplatek","year":"2006","journal-title":"J Burn Care Res"},{"key":"10.1038\/jid.2012.510_bb0110","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1097\/00004630-200203000-00004","article-title":"A multicenter review of toxic epidermal necrolysis treated in U.S. burn centers at the end of the twentieth century","volume":"23","author":"Palmieri","year":"2002","journal-title":"J Burn Care Rehabil"},{"key":"10.1038\/jid.2012.510_bb0115","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1001\/archderm.1990.01670250043005","article-title":"Toxic epidermal necrolysis (Lyell syndrome): incidence and drug etiology in France, 1981-1985","volume":"126","author":"Roujeau","year":"1990","journal-title":"Arch Dermatol"},{"key":"10.1038\/jid.2012.510_bb0120","volume":"303","author":"Royston","year":"2008"},{"key":"10.1038\/jid.2012.510_bb0125","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/0895-4356(96)00035-2","article-title":"Epidemiology of erythema exsudativum multiforme majus, Stevens-Johnson syndrome, and toxic epidermal necrolysis in Germany (1990-1992): Structure and results of a population-based registry","volume":"49","author":"Rzany","year":"1996","journal-title":"J Clin Epidemiol"},{"key":"10.1038\/jid.2012.510_bb0130","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1038\/clpt.2009.252","article-title":"ALDEN, an algorithm for assessment of drug causality in Stevens-Johnson syndrome and toxic epidermal necrolysis: Comparison with case-control analysis","volume":"88","author":"Sassolas","year":"2010","journal-title":"Clin Pharmacol Ther"},{"key":"10.1038\/jid.2012.510_bb0135","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1002\/bimj.200610328","article-title":"A new proposal for multivariable modelling of time-varying effects in survival data based on fractional polynomial time-transformation","volume":"49","author":"Sauerbrei","year":"2007","journal-title":"Biom J"},{"key":"10.1038\/jid.2012.510_bb0140","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1097\/00004630-200021030-00004","article-title":"A 10-year experience with toxic epidermal necrolysis","volume":"21","author":"Schulz","year":"2000","journal-title":"J Burn Care Rehabil"},{"key":"10.1038\/jid.2012.510_bb0145","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1097\/BCR.0b013e31820aafbc","article-title":"Evaluation of SCORTEN on a cohort of patients with Stevens-Johnson syndrome and toxic epidermal necrolysis included in the RegiSCAR-study","volume":"32","author":"Sekula","year":"2011","journal-title":"J Burn Care Res"},{"key":"10.1038\/jid.2012.510_bb0150","series-title":"Fitzpatrick\u2019s Dermatology in General Medicine","first-page":"349","article-title":"Epidermal necrolysis (Stevens-Johnsons syndrome and toxic epidermal necrolysis)","author":"Valeyrie-Allanore","year":"2008"},{"key":"10.1038\/jid.2012.510_bb0155","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1111\/j.1365-2133.2010.09863.x","article-title":"Open trial of ciclosporin treatment for Stevens-Johnson syndrome and toxic epidermal necrolysis","volume":"163","author":"Valeyrie-Allanore","year":"2010","journal-title":"Br J Dermatol"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X1536214X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X1536214X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,6]],"date-time":"2025-04-06T20:44:54Z","timestamp":1743972294000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X1536214X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["S0022202X1536214X"],"URL":"https:\/\/doi.org\/10.1038\/jid.2012.510","relation":{},"ISSN":["0022-202X"],"issn-type":[{"value":"0022-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comprehensive Survival Analysis of a Cohort of Patients with Stevens\u2013Johnson Syndrome and Toxic Epidermal Necrolysis","name":"articletitle","label":"Article Title"},{"value":"Journal of Investigative Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/jid.2012.510","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 The Society for Investigative Dermatology, Inc. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}