{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T05:37:06Z","timestamp":1790487426315,"version":"4.1.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2015,12,2]],"date-time":"2015-12-02T00:00:00Z","timestamp":1449014400000},"content-version":"vor","delay-in-days":884,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jidonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1038\/jid.2013.19","type":"journal-article","created":{"date-parts":[[2013,1,18]],"date-time":"2013-01-18T14:53:00Z","timestamp":1358520780000},"page":"1752-1759","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":262,"title":["Climatic Factors Are Associated with Childhood Eczema Prevalence in the United States"],"prefix":"10.1016","volume":"133","author":[{"given":"Jonathan I.","family":"Silverberg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon","family":"Hanifin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric L.","family":"Simpson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/jid.2013.19_bb0010","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1046\/j.1365-2133.2001.04007.x","article-title":"Epidermal interleukin-1 alpha generation is amplified at low humidity: implications for the pathogenesis of inflammatory dermatoses","volume":"144","author":"Ashida","year":"2001","journal-title":"Br J Dermatol"},{"key":"10.1038\/jid.2013.19_bb0015","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate - a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J R Stat Soc Ser B Stat Methodol"},{"key":"10.1038\/jid.2013.19_bb0020","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1001\/jama.1962.03050130009003","article-title":"Pruritic skin disease and summer air conditioning","volume":"179","author":"Chernosky","year":"1962","journal-title":"JAMA"},{"key":"10.1038\/jid.2013.19_bb0025","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1046\/j.1523-1747.1998.00364.x","article-title":"Low humidity stimulates epidermal DNA synthesis and amplifies the hyperproliferative response to barrier disruption: implication for seasonal exacerbations of inflammatory dermatoses","volume":"111","author":"Denda","year":"1998","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2013.19_bb0030","doi-asserted-by":"crossref","first-page":"438","DOI":"10.2500\/aap.2011.32.3485","article-title":"Vitamin D deficiency as a risk factor for allergic disorders and immune mechanisms","volume":"32","author":"Frieri","year":"2011","journal-title":"Allergy Asthma Proc"},{"key":"10.1038\/jid.2013.19_bb0035","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/jid.1952.61","article-title":"Relation of dew point and barometric pressure to chapping of normal skin","volume":"19","author":"Gaul","year":"1952","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2013.19_bb0040","series-title":"Science: Ozone Basics","author":"Gleason","year":"2012"},{"key":"10.1038\/jid.2013.19_bb0045","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/S0277-9536(98)00151-8","article-title":"Asthma and domestic air quality","volume":"47","author":"Jones","year":"1998","journal-title":"Soc Sci Med"},{"key":"10.1038\/jid.2013.19_bb0050","doi-asserted-by":"crossref","first-page":"3192","DOI":"10.3390\/ijerph8083192","article-title":"Prevalence of symptoms of severe asthma and allergies in Irish school children: an ISAAC protocol study, 1995-2007","volume":"8","author":"Kabir","year":"2011","journal-title":"Int J Environ Res Public Health"},{"key":"10.1038\/jid.2013.19_bb0055","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/BF02289233","article-title":"The varimax criterion for analytic rotation in factor analysis","volume":"23","author":"Kaiser","year":"1958","journal-title":"Psychometrika"},{"key":"10.1038\/jid.2013.19_bb0060","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1175\/1520-0450(1986)025<0145:AMTETT>2.0.CO;2","article-title":"A model to estimate the time of observation bias associated with monthly mean maximum, minimum and mean temperatures for the United States","volume":"25","author":"Karl","year":"1986","journal-title":"J Climate Appl Meteor"},{"key":"10.1038\/jid.2013.19_bb0065","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1111\/j.1365-2133.2006.07153.x","article-title":"An exploratory prospective observational study of environmental factors exacerbating atopic eczema in children","volume":"154","author":"Langan","year":"2006","journal-title":"Br J Dermatol"},{"key":"10.1038\/jid.2013.19_bb0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/09603120903254033","article-title":"Relationship between ambient ozone concentrations and daily hospital admissions for childhood asthma\/atopic dermatitis in two cities of Korea during 2004-2005","volume":"20","author":"Lee","year":"2010","journal-title":"Int J Environ Health Res"},{"key":"10.1038\/jid.2013.19_bb0075","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1111\/j.1751-1097.2011.00969.x","article-title":"The consequences of UV-induced immunosuppression for human health","volume":"87","author":"Norval","year":"2011","journal-title":"Photochem Photobiol"},{"key":"10.1038\/jid.2013.19_bb0080","series-title":"The Times Books World Weather Guide: A City-by-City Guide That Will Enable You to Forecast the Weather You Can Expect in Any Part of the World at Any Time of the Year","first-page":"480","author":"Pearce","year":"1984"},{"key":"10.1038\/jid.2013.19_bb0085","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1111\/j.1365-2133.2010.10147.x","article-title":"Correlation between serum 25-hydroxyvitamin D levels and severity of atopic dermatitis in children","volume":"164","author":"Peroni","year":"2011","journal-title":"Br J Dermatol"},{"key":"10.1038\/jid.2013.19_bb0090","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1093\/oxfordjournals.aje.a114892","article-title":"The ecological fallacy","volume":"127","author":"Piantadosi","year":"1988","journal-title":"Am J Epidemiol"},{"key":"10.1038\/jid.2013.19_bb0095","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1111\/j.1365-4362.1986.tb02249.x","article-title":"Atopic dermatitis. Correlation of environmental factors with frequency","volume":"25","author":"Rajka","year":"1986","journal-title":"Int J Dermatol"},{"key":"10.1038\/jid.2013.19_bb0100","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1111\/j.1600-0536.1980.tb05572.x","article-title":"Low humidity occupational dermatoses","volume":"6","author":"Rycroft","year":"1980","journal-title":"Contact Dermatitis"},{"key":"10.1038\/jid.2013.19_bb0105","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1046\/j.1523-1747.2002.00589.x","article-title":"Abrupt decreases in environmental humidity induce abnormalities in permeability barrier homeostasis","volume":"119","author":"Sato","year":"2002","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2013.19_bb0110","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1097\/00001648-199601000-00005","article-title":"Air pollution and hospital admissions for respiratory disease","volume":"7","author":"Schwartz","year":"1996","journal-title":"Epidemiology"},{"key":"10.1038\/jid.2013.19_bb0115","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1111\/j.1398-9995.2005.00797.x","article-title":"Diverging prevalence trends of atopic disorders in Norwegian children. Results from three cross-sectional studies","volume":"60","author":"Selnes","year":"2005","journal-title":"Allergy"},{"key":"10.1038\/jid.2013.19_bb0120","first-page":"6","article-title":"Prevalence of symptoms of asthma, rhinitis, and atopic eczema in Brazilian adolescents related to exposure to gaseous air pollutants and socioeconomic status","volume":"17","author":"Sole","year":"2007","journal-title":"J Investig Allergol Clin Immunol"},{"key":"10.1038\/jid.2013.19_bb0125","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1007\/s00484-008-0177-0","article-title":"Climate and prevalence of atopic eczema in 6- to 7-year-old school children in Spain. ISAAC phase III","volume":"52","author":"Suarez-Varela","year":"2008","journal-title":"Int J Biometeorol"},{"key":"10.1038\/jid.2013.19_bb0130","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/j.1365-2133.2010.09767.x","article-title":"Narrowband ultraviolet B treatment improves vitamin D balance and alters antimicrobial peptide expression in skin lesions of psoriasis and atopic dermatitis","volume":"163","author":"Vahavihu","year":"2010","journal-title":"Br J Dermatol"},{"key":"10.1038\/jid.2013.19_bb0135","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1136\/oem.2002.006809","article-title":"Climate and the prevalence of symptoms of asthma, allergic rhinitis, and atopic eczema in children","volume":"61","author":"Weiland","year":"2004","journal-title":"Occup Environ Med"},{"key":"10.1038\/jid.2013.19_bb0140","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/S1081-1206(10)62852-9","article-title":"Clinical aspects, epidemiology, and prognosis of atopic dermatitis","volume":"83","author":"Wuthrich","year":"1999","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1038\/jid.2013.19_bb0145","first-page":"1","article-title":"The atopic eczema\/dermatitis syndrome. Epidemiology, natural course, and immunology of the IgE-associated (\u201cextrinsic\u201d) and the nonallergic (\u201cintrinsic\u201d) AEDS","volume":"13","author":"Wuthrich","year":"2003","journal-title":"J Investig Allergol Clin Immunol"},{"key":"10.1038\/jid.2013.19_bb0150","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1111\/j.1399-3038.2007.00554.x","article-title":"The changing prevalence of asthma, allergic rhinitis and atopic eczema in African adolescents from 1995 to 2002","volume":"18","author":"Zar","year":"2007","journal-title":"Pediatr Allergy Immunol"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X1536320X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X1536320X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,6]],"date-time":"2025-04-06T20:54:14Z","timestamp":1743972854000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X1536320X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":29,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["S0022202X1536320X"],"URL":"https:\/\/doi.org\/10.1038\/jid.2013.19","relation":{},"ISSN":["0022-202X"],"issn-type":[{"value":"0022-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Climatic Factors Are Associated with Childhood Eczema Prevalence in the United States","name":"articletitle","label":"Article Title"},{"value":"Journal of Investigative Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/jid.2013.19","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 The Society for Investigative Dermatology, Inc. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}