{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T11:44:59Z","timestamp":1786621499294,"version":"build-2736575974"},"reference-count":24,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,4,1]],"date-time":"2016-04-01T00:00:00Z","timestamp":1459468800000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["jidonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1038\/jid.2014.528","type":"journal-article","created":{"date-parts":[[2014,12,18]],"date-time":"2014-12-18T14:48:29Z","timestamp":1418914109000},"page":"1089-1097","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"title":["BAP1 Has a Survival Role in Cutaneous Melanoma"],"prefix":"10.1016","volume":"135","author":[{"given":"Raj","family":"Kumar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benchun","family":"Miao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenyu","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny C-N.","family":"Njauw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00f6ran","family":"J\u00f6nsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennie T.","family":"Frederick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hensin","family":"Tsao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/jid.2014.528_bb0010","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1136\/jmedgenet-2011-100156","article-title":"Germline BAP1 mutation predisposes to uveal melanoma, lung adenocarcinoma, meningioma, and other cancers","volume":"48","author":"Abdel-Rahman","year":"2011","journal-title":"J Med Genet"},{"key":"10.1038\/jid.2014.528_bb0015","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1038\/ng.855","article-title":"The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma","volume":"43","author":"Bott","year":"2011","journal-title":"Nat Genet"},{"key":"10.1038\/jid.2014.528_bb0020","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/nrc3459","article-title":"BAP1 and cancer","volume":"13","author":"Carbone","year":"2013","journal-title":"Nat Rev Cancer"},{"key":"10.1038\/jid.2014.528_bb0025","first-page":"267","article-title":"Effects of maternal fasting on hepatic gluconeogenesis and glucose metabolism in fetal lambs","volume":"16","author":"Dalinghaus","year":"1991","journal-title":"J Dev Physiol"},{"key":"10.1038\/jid.2014.528_bb0030","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1126\/science.1221711","article-title":"Loss of the tumor suppressor BAP1 causes myeloid transformation","volume":"337","author":"Dey","year":"2012","journal-title":"Science"},{"key":"10.1038\/jid.2014.528_bb0035","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1126\/science.1194472","article-title":"Frequent mutation of BAP1 in metastasizing uveal melanomas","volume":"330","author":"Harbour","year":"2010","journal-title":"Science"},{"key":"10.1038\/jid.2014.528_bb0040","doi-asserted-by":"crossref","first-page":"4026","DOI":"10.1158\/1078-0432.CCR-12-0343","article-title":"Molecular profiling reveals low- and high-grade forms of primary melanoma","volume":"18","author":"Harbst","year":"2012","journal-title":"Clin Cancer Res"},{"key":"10.1038\/jid.2014.528_bb0045","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1038\/sj.onc.1201861","article-title":"BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression","volume":"16","author":"Jensen","year":"1998","journal-title":"Oncogene"},{"key":"10.1038\/jid.2014.528_bb0050","doi-asserted-by":"crossref","first-page":"4383","DOI":"10.1158\/1078-0432.CCR-13-0074","article-title":"Vemurafenib synergizes with nutlin-3 to deplete survivin and suppresses melanoma viability and tumor growth","volume":"19","author":"Ji","year":"2013","journal-title":"Clin Cancer Res"},{"key":"10.1038\/jid.2014.528_bb0055","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1038\/jid.2011.313","article-title":"p53 rescue through HDM2 antagonism suppresses melanoma growth and potentiates MEK inhibition","volume":"132","author":"Ji","year":"2012","journal-title":"J Investig Dermatol Symp Proc"},{"key":"10.1038\/jid.2014.528_bb0060","doi-asserted-by":"crossref","first-page":"4026","DOI":"10.1158\/1078-0432.CCR-12-0343","article-title":"Molecular profiling reveals low- and high-grade forms of primary melanoma","volume":"18","author":"Katja","year":"2012","journal-title":"Clin Cancer Res"},{"key":"10.1038\/jid.2014.528_bb0065","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1038\/ncb1659","article-title":"Genome-scale RNAi profiling of cell division in human tissue culture cells","volume":"9","author":"Kittler","year":"2007","journal-title":"Nat Cell Biol"},{"key":"10.1038\/jid.2014.528_bb0070","doi-asserted-by":"crossref","first-page":"34179","DOI":"10.1074\/jbc.M109.046755","article-title":"The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1","volume":"284","author":"Machida","year":"2009","journal-title":"J Biol Chem"},{"key":"10.1038\/jid.2014.528_bb0075","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1186\/1471-2407-13-371","article-title":"BAP1 deficiency causes loss of melanocytic cell identity in uveal melanoma","volume":"13","author":"Matatall","year":"2013","journal-title":"BMC Cancer"},{"key":"10.1038\/jid.2014.528_bb0080","first-page":"397","article-title":"Role of the apoptotic and mitotic regulator survivin in melanoma","volume":"32","author":"McKenzie","year":"2012","journal-title":"Anticancer Res"},{"key":"10.1038\/jid.2014.528_bb0085","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1097\/PAT.0b013e3283653818","article-title":"BAP1 expression in cutaneous melanoma: a pilot study","volume":"45","author":"Murali","year":"2013","journal-title":"Pathology"},{"key":"10.1038\/jid.2014.528_bb0090","doi-asserted-by":"crossref","first-page":"e35295","DOI":"10.1371\/journal.pone.0035295","article-title":"Germline BAP1 inactivation is preferentially associated with metastatic ocular melanoma and cutaneous-ocular melanoma families","volume":"7","author":"Njauw","year":"2012","journal-title":"PloS One"},{"key":"10.1038\/jid.2014.528_bb0095","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1038\/ng.2323","article-title":"BAP1 loss defines a new class of renal cell carcinoma","volume":"44","author":"Pena-Llopis","year":"2012","journal-title":"Nat Genet"},{"key":"10.1038\/jid.2014.528_bb0100","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1126\/science.1149200","article-title":"Cancer proliferation gene discovery through functional genomics","volume":"319","author":"Schlabach","year":"2008","journal-title":"Science"},{"key":"10.1038\/jid.2014.528_bb0105","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1097\/PAT.0000000000000002","article-title":"BAP1 protein loss by immunohistochemistry: a potentially useful tool for prognostic prediction in patients with uveal melanoma","volume":"45","author":"Shah","year":"2013","journal-title":"Pathology"},{"key":"10.1038\/jid.2014.528_bb0110","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1038\/ng.912","article-title":"Germline BAP1 mutations predispose to malignant mesothelioma","volume":"43","author":"Testa","year":"2011","journal-title":"Nat Genet"},{"key":"10.1038\/jid.2014.528_bb0115","doi-asserted-by":"crossref","first-page":"4921","DOI":"10.1038\/onc.2011.210","article-title":"Epha2 is a critical oncogene in melanoma","volume":"30","author":"Udayakumar","year":"2011","journal-title":"Oncogene"},{"key":"10.1038\/jid.2014.528_bb0120","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1038\/ng.910","article-title":"Germline mutations in BAP1 predispose to melanocytic tumors","volume":"43","author":"Wiesner","year":"2011","journal-title":"Nat Genet"},{"key":"10.1038\/jid.2014.528_bb0125","doi-asserted-by":"crossref","first-page":"5071","DOI":"10.1128\/MCB.00396-10","article-title":"The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression","volume":"30","author":"Yu","year":"2010","journal-title":"Mol Cell Biol"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X15371888?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X15371888?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,6]],"date-time":"2025-04-06T21:53:27Z","timestamp":1743976407000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X15371888"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["S0022202X15371888"],"URL":"https:\/\/doi.org\/10.1038\/jid.2014.528","relation":{},"ISSN":["0022-202X"],"issn-type":[{"value":"0022-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2015,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"BAP1 Has a Survival Role in Cutaneous Melanoma","name":"articletitle","label":"Article Title"},{"value":"Journal of Investigative Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/jid.2014.528","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 The Society for Investigative Dermatology, Inc. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}