{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T23:51:29Z","timestamp":1790553089808,"version":"4.1.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["jidonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2015,9]]},"DOI":"10.1038\/jid.2015.87","type":"journal-article","created":{"date-parts":[[2015,3,5]],"date-time":"2015-03-05T14:43:33Z","timestamp":1425566613000},"page":"2189-2197","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":148,"title":["Psoriasis and the Risk of Major Cardiovascular Events: Cohort Study Using the Clinical Practice Research Datalink"],"prefix":"10.1016","volume":"135","author":[{"given":"Rosa","family":"Parisi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin K.","family":"Rutter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Lunt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen S.","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah P.M.","family":"Symmons","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher E.M.","family":"Griffiths","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren M.","family":"Ashcroft","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/jid.2015.87_bb0010","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1111\/j.1365-2796.2010.02310.x","article-title":"Psoriasis is associated with clinically significant cardiovascular risk: a Danish Nationwide Cohort Study","volume":"270","author":"Ahlehoff","year":"2011","journal-title":"J Intern Med"},{"key":"10.1038\/jid.2015.87_bb0015","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.1093\/eurheartj\/ehr285","article-title":"Psoriasis and risk of atrial fibrillation and ischaemic stroke: a Danish Nationwide Cohort Study","volume":"33","author":"Ahlehoff","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1038\/jid.2015.87_bb0020","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/j.1600-0625.2011.01261.x","article-title":"The \u2018psoriatic march\u2019: a concept of how severe psoriasis may drive cardiovascular comorbidity","volume":"20","author":"Boehncke","year":"2011","journal-title":"Exp Dermatol"},{"key":"10.1038\/jid.2015.87_bb0025","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1111\/j.1365-2133.2008.09020.x","article-title":"Psoriasis and risk of incident myocardial infarction, stroke or transient ischaemic attack: an inception cohort study with a nested case\u2013control analysis","volume":"160","author":"Brauchli","year":"2009","journal-title":"Br J Dermatol"},{"key":"10.1038\/jid.2015.87_bb0030","series-title":"English indices of deprivation 2010: guidance","author":"Department for Communities and Local Government","year":"2010"},{"key":"10.1038\/jid.2015.87_bb0035","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1038\/jid.2013.131","article-title":"Psoriasis is not associated with atherosclerosis and incident cardiovascular events: the Rotterdam Study","volume":"133","author":"Dowlatshahi","year":"2013","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2015.87_bb0040","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1161\/CIRCULATIONAHA.114.009990","article-title":"Chronic inflammatory disorders and risk of type 2 diabetes mellitus, coronary heart disease, and stroke: a population-based cohort study","volume":"130","author":"Dregan","year":"2014","journal-title":"Circulation"},{"key":"10.1038\/jid.2015.87_bb0045","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1136\/bmj.39335.541782.AD","article-title":"Strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"335","author":"Erik von","year":"2007","journal-title":"Br Med J"},{"key":"10.1038\/jid.2015.87_bb0050","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1001\/archderm.139.11.1425","article-title":"Lymphoma rates are low but increased in patients with psoriasis: results from a population-based cohort study in the United Kingdom","volume":"139","author":"Gelfand","year":"2003","journal-title":"Arch Dermatol"},{"key":"10.1038\/jid.2015.87_bb0055","doi-asserted-by":"crossref","first-page":"2411","DOI":"10.1038\/jid.2009.112","article-title":"The risk of stroke in patients with psoriasis","volume":"129","author":"Gelfand","year":"2009","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2015.87_bb0060","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1016\/j.jaad.2004.04.014","article-title":"Determinants of quality of life in patients with psoriasis: a study from the US population","volume":"51","author":"Gelfand","year":"2004","journal-title":"J Am Acad Dermatol"},{"key":"10.1038\/jid.2015.87_bb0065","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1001\/jama.296.14.1735","article-title":"Risk of myocardial infarction in patients with psoriasis","volume":"296","author":"Gelfand","year":"2006","journal-title":"JAMA"},{"key":"10.1038\/jid.2015.87_bb0070","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0140-6736(07)61128-3","article-title":"Pathogenesis and clinical features of psoriasis","volume":"370","author":"Griffiths","year":"2007","journal-title":"Lancet"},{"key":"10.1038\/jid.2015.87_bb0075","doi-asserted-by":"crossref","first-page":"e7168","DOI":"10.1371\/journal.pone.0007168","article-title":"Selection of medical diagnostic codes for analysis of electronic patient records. Application to stroke in a primary care database","volume":"4","author":"Gulliford","year":"2009","journal-title":"PLoS One"},{"key":"10.1038\/jid.2015.87_bb0080","first-page":"2167","article-title":"Cardiovascular disease and risk factors in patients with rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis","volume":"33","author":"Han","year":"2006","journal-title":"J Rheumatol"},{"key":"10.1038\/jid.2015.87_bb0085","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/j.1365-2125.2009.03537.x","article-title":"Validation and validity of diagnoses in the General Practice Research Database: a systematic review","volume":"69","author":"Herrett","year":"2010","journal-title":"Br J Clin Pharmacol"},{"key":"10.1038\/jid.2015.87_bb0090","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1136\/bmj.302.6779.766","article-title":"Validation of information recorded on general practitioner based computerised data resource in the United Kingdom","volume":"302","author":"Jick","year":"1991","journal-title":"Br Med J"},{"key":"10.1038\/jid.2015.87_bb0095","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.ejim.2012.06.016","article-title":"Inflammatory arthritis as a novel risk factor for cardiovascular disease","volume":"23","author":"John","year":"2012","journal-title":"Eur J Intern Med"},{"key":"10.1038\/jid.2015.87_bb0100","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1111\/j.1365-2133.2008.08707.x","article-title":"Incidence of risk factors for myocardial infarction and other vascular diseases in patients with psoriasis","volume":"159","author":"Kaye","year":"2008","journal-title":"Br J Dermatol"},{"key":"10.1038\/jid.2015.87_bb0105","doi-asserted-by":"crossref","first-page":"e128","DOI":"10.3399\/bjgp10X483562","article-title":"Validity of diagnostic coding within the General Practice Research Database: a systematic review","volume":"60","author":"Khan","year":"2010","journal-title":"Br J Gen Pract"},{"key":"10.1038\/jid.2015.87_bb0110","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.jaad.2013.11.023","article-title":"Increased risk of diabetes mellitus in relation to the severity of psoriasis, concomitant medication, and comorbidity: A nationwide population-based cohort study","volume":"70","author":"Lee","year":"2014","journal-title":"J Am Acad Dermatol"},{"key":"10.1038\/jid.2015.87_bb0115","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1111\/j.1365-2133.2011.10774.x","article-title":"Psoriasis and risk of nonfatal cardiovascular disease in U.S. women: a cohort study","volume":"166","author":"Li","year":"2012","journal-title":"Br J Dermatol"},{"key":"10.1038\/jid.2015.87_bb0120","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.jaad.2010.01.050","article-title":"Increased risk of acute myocardial infarction in patients with psoriasis: a 5-year population-based study in Taiwan","volume":"64","author":"Lin","year":"2011","journal-title":"J Am Acad Dermatol"},{"key":"10.1038\/jid.2015.87_bb0125","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1365-2133.2006.07562.x","article-title":"Psoriasis: a possible risk factor for development of coronary artery calcification","volume":"156","author":"Ludwig","year":"2007","journal-title":"Br J Dermatol"},{"key":"10.1038\/jid.2015.87_bb0130","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1023\/B:EJEP.0000020447.59150.f9","article-title":"Increased risk for cardiovascular mortality in psoriasis inpatients but not in outpatients","volume":"19","author":"Mallbris","year":"2004","journal-title":"Eur J Epidemiol"},{"key":"10.1038\/jid.2015.87_bb0135","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1093\/eurheartj\/ehp567","article-title":"Patients with severe psoriasis are at increased risk of cardiovascular mortality: cohort study using the General Practice Research Database","volume":"31","author":"Mehta","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1038\/jid.2015.87_bb0140","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1111\/j.0022-202X.2005.23681.x","article-title":"Cigarette smoking, body mass index, and stressful life events as risk factors for psoriasis: results from an Italian Case-Control Study","volume":"125","author":"Naldi","year":"2005","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2015.87_bb0145","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.jaad.2006.08.040","article-title":"Prevalence of cardiovascular risk factors in patients with psoriasis","volume":"55","author":"Neimann","year":"2006","journal-title":"J Am Acad Dermatol"},{"key":"10.1038\/jid.2015.87_bb0150","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1038\/jid.2009.55","article-title":"Complexity of the association between psoriasis and comorbidities","volume":"129","author":"Nijsten","year":"2009","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2015.87_bb0155","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1136\/annrheumdis-2014-205675","article-title":"Risk of major cardiovascular events in patients with psoriatic arthritis, psoriasis and rheumatoid arthritis: a population-based cohort study","volume":"74","author":"Ogdie","year":"2015","journal-title":"Ann Rheum Dis"},{"key":"10.1038\/jid.2015.87_bb0160","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1038\/jid.2012.339","article-title":"Global epidemiology of psoriasis: a systematic review of incidence and prevalence","volume":"133","author":"Parisi","year":"2013","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2015.87_bb0165","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S0190-9622(99)70112-X","article-title":"Psoriasis causes as much disability as other major medical diseases","volume":"41","author":"Rapp","year":"1999","journal-title":"J Am Acad Dermatol"},{"key":"10.1038\/jid.2015.87_bb0170","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1136\/jamia.1997.0040465","article-title":"Updating the read codes: user-interactive maintenance of a dynamic clinical vocabulary","volume":"4","author":"Robinson","year":"1997","journal-title":"J Am Med Inform Assoc"},{"key":"10.1038\/jid.2015.87_bb0175","doi-asserted-by":"crossref","first-page":"2340","DOI":"10.1038\/jid.2013.149","article-title":"Incidence of cardiovascular disease in individuals with psoriasis: a systematic review and meta-analysis","volume":"133","author":"Samarasekera","year":"2013","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2015.87_bb0180","doi-asserted-by":"crossref","first-page":"178","DOI":"10.7861\/clinmedicine.14-2-178","article-title":"Psoriasis: guidance on assessment and referral","volume":"14","author":"Samarasekera","year":"2014","journal-title":"Clin Med"},{"key":"10.1038\/jid.2015.87_bb0185","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1001\/archinte.167.15.1670","article-title":"Obesity, waist circumference, weight change, and the risk of psoriasis in women: Nurses' health study II","volume":"167","author":"Setty","year":"2007","journal-title":"Arch Int Med"},{"key":"10.1038\/jid.2015.87_bb0190","doi-asserted-by":"crossref","first-page":"e99825","DOI":"10.1371\/journal.pone.0099825","article-title":"ClinicalCodes: an online clinical codes repository to improve the validity and reproducibility of research using electronic medical records","volume":"9","author":"Springate","year":"2014","journal-title":"PLoS One"},{"key":"10.1038\/jid.2015.87_bb0195","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1038\/jid.2010.399","article-title":"Very severe psoriasis is associated with increased noncardiovascular mortality but not with increased cardiovascular risk","volume":"131","author":"Stern","year":"2011","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2015.87_bb0200","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1046\/j.1087-0024.2003.09102.x","article-title":"Psoriasis is common, carries a substantial burden even when not extensive, and is associated with widespread treatment dissatisfaction","volume":"9","author":"Stern","year":"2004","journal-title":"J Invest Dermatol Symp Proc"},{"key":"10.1038\/jid.2015.87_bb0205","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/nrrheum.2011.75","article-title":"Epidemiology of CVD in rheumatic disease, with a focus on RA and SLE","volume":"7","author":"Symmons","year":"2011","journal-title":"Nat Rev Rheumatol"},{"key":"10.1038\/jid.2015.87_bb0210","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1038\/jid.2009.321","article-title":"Psoriasis may not be an independent risk factor for acute ischemic heart disease hospitalizations: results of a large population-based Dutch cohort","volume":"130","author":"Wakkee","year":"2010","journal-title":"J Invest Dermatol"},{"key":"10.1038\/jid.2015.87_bb0215","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1093\/rheumatology\/kep366","article-title":"The effect of methotrexate on cardiovascular disease in patients with rheumatoid arthritis: a systematic literature review","volume":"49","author":"Westlake","year":"2010","journal-title":"Rheumatology (Oxford)"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X15390266?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X15390266?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,6]],"date-time":"2025-04-06T22:07:30Z","timestamp":1743977250000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X15390266"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":42,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["S0022202X15390266"],"URL":"https:\/\/doi.org\/10.1038\/jid.2015.87","relation":{},"ISSN":["0022-202X"],"issn-type":[{"value":"0022-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2015,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Psoriasis and the Risk of Major Cardiovascular Events: Cohort Study Using the Clinical Practice Research Datalink","name":"articletitle","label":"Article Title"},{"value":"Journal of Investigative Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/jid.2015.87","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 The Society for Investigative Dermatology, Inc. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}