{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T23:12:23Z","timestamp":1790291543631,"version":"4.1.0"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"S1","license":[{"start":{"date-parts":[[2009,1,28]],"date-time":"2009-01-28T00:00:00Z","timestamp":1233100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2009,1,28]],"date-time":"2009-01-28T00:00:00Z","timestamp":1233100800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Perinatol"],"published-print":{"date-parts":[[2009,2]]},"DOI":"10.1038\/jp.2008.211","type":"journal-article","created":{"date-parts":[[2009,1,28]],"date-time":"2009-01-28T14:29:55Z","timestamp":1233152995000},"page":"S25-S45","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":290,"title":["Clinical report from the pilot USA Kernicterus Registry (1992 to 2004)"],"prefix":"10.1038","volume":"29","author":[{"given":"L","family":"Johnson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V K","family":"Bhutani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Karp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E M","family":"Sivieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S M","family":"Shapiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2009,1,28]]},"reference":[{"key":"BFjp2008211_CR1","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1542\/peds.28.6.870","volume":"28","author":"R Van Praagh","year":"1961","unstructured":"Van Praagh R . Diagnosis of kernicterus in the neonatal period. Pediatrics 1961; 28: 870\u2013874.","journal-title":"Pediatrics"},{"key":"BFjp2008211_CR2","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1542\/peds.14.4.346","volume":"14","author":"MH Jones","year":"1954","unstructured":"Jones MH, Sands R, Hyman CB, Sturgeon P, Koch FP . Longitudinal study of the incidence of central nervous system damage following erythroblastosis fetalis. Pediatrics 1954; 14: 346.","journal-title":"Pediatrics"},{"key":"BFjp2008211_CR3","first-page":"605","volume":"79","author":"M Perlstein","year":"1950","unstructured":"Perlstein M . Neurologic sequelae of erythroblastosis fetalis. Am J Dis Child 1950; 79: 605\u2013606.","journal-title":"Am J Dis Child"},{"key":"BFjp2008211_CR4","unstructured":"Volpe JJ . Bilirubin and brain injury. In: Volpe JJ (ed). Neurology of the Newborn, 4th edn. 2001."},{"key":"BFjp2008211_CR5","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1542\/peds.104.S6.1208","volume":"104","author":"L Johnson","year":"1999","unstructured":"Johnson L, Brown AK, Bhutani V . BIND\u2014a clinical score for bilirubin induced neurologic dysfunction in newborns. Pediatrics 1999; 104: 746.","journal-title":"Pediatrics"},{"key":"BFjp2008211_CR6","unstructured":"Bhutani VK, Johnson L, Keren R . Acute bilirubin encephalopathy\u2026 before it is too late. Contemporary Pediatr 2005; 54\u201374. http:\/\/www.modernmedicine.com\/modernmedicine\/Features\/Treating-acute-bilirubin-encephalopathy--before-it\/ArticleStandard\/Article\/detail\/161379."},{"issue":"1","key":"BFjp2008211_CR7","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1038\/sj.jp.7211157","volume":"25","author":"SM Shapiro","year":"2005","unstructured":"Shapiro SM . Definition of the clinical spectrum of kernicterus and bilirubin-induced neurologic dysfunction (BIND). J Perinatol 2005; 25 (1): 54\u201359.","journal-title":"J Perinatol"},{"issue":"2","key":"BFjp2008211_CR8","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/j.clp.2006.03.010","volume":"33","author":"SM Shapiro","year":"2006","unstructured":"Shapiro SM, Bhutani VK, Johnson L . Hyperbilirubinemia and kernicterus. Clin Perinatol 2006; 33 (2): 387\u2013410.","journal-title":"Clin Perinatol"},{"key":"BFjp2008211_CR9","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/S0022-3476(70)80124-X","volume":"76","author":"GB Odell","year":"1970","unstructured":"Odell GB, Storey GNB, Rosenberg LA . Studies in kernicterus. III. The saturation of serum proteins with bilirubin during neonatal life and its relationship to brain damage at five years. J Pediatr 1970; 76: 12\u201321.","journal-title":"J Pediatr"},{"key":"BFjp2008211_CR10","first-page":"122","volume-title":"Phototherapy in the Newborn: An Overview","author":"L Johnson","year":"1974","unstructured":"Johnson L, Boggs Jr TR . Bilirubin-dependent brain damage: incidence and indication for treatment. In: Odell GB, Schaffer R, Simopoulous AP (eds). Phototherapy in the Newborn: An Overview. National Academy of Sciences: Washington, DC, 1974, pp 122\u2013149."},{"key":"BFjp2008211_CR11","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1542\/peds.38.4.539","volume":"38","author":"I Diamond","year":"1966","unstructured":"Diamond I . Kernicterus: revised concepts of pathogenesis and management. Pediatrics 1966; 38: 539\u2013542.","journal-title":"Pediatrics"},{"issue":"1:3","key":"BFjp2008211_CR12","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1542\/peds.6.3.452","volume":"6","author":"WW Zuelzer","year":"1950","unstructured":"Zuelzer WW, Mudgett RT . Kernicterus; etiologic study based on an analysis of 55 cases. Pediatrics 1950; 6 (1:3): 452\u2013474.","journal-title":"Pediatrics"},{"key":"BFjp2008211_CR13","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1542\/peds.94.4.558","volume":"94","author":"American Academy of Pediatrics, Provisional Committee for Quality Improvement","year":"1994","unstructured":"American Academy of Pediatrics, Provisional Committee for Quality Improvement. Practice parameter: management of hyperbilirubinemia in the healthy term newborn. Pediatrics 1994; 94: 558\u2013565.","journal-title":"Pediatrics"},{"issue":"3","key":"BFjp2008211_CR14","first-page":"902","volume":"114","author":"RH Palmer","year":"2004","unstructured":"Palmer RH, Ezhuthachan S, Newman C, Maisels MJ, Testa MA . Management of hyperbilirubinemia in newborns: measuring performance using a benchmarking model. Pediatrics 2004; 114 (3): 902.","journal-title":"Pediatrics"},{"key":"BFjp2008211_CR15","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1016\/S0095-5108(18)30097-6","volume":"25","author":"LH Johnson","year":"1998","unstructured":"Johnson LH, Bhutani VK . Guidelines for management of the jaundiced term and near-term infant. Clin Perinatol 1998; 25: 555\u2013574.","journal-title":"Clin Perinatol"},{"key":"BFjp2008211_CR16","first-page":"488","volume":"93","author":"L Johnson","year":"2002","unstructured":"Johnson L, Brown AK, Bhutani VK . System-based approach to management of neonatal jaundice and prevention of kernicterus. J Pediatr 2002; 93: 488\u2013494.","journal-title":"J Pediatr"},{"key":"BFjp2008211_CR17","doi-asserted-by":"crossref","unstructured":"American Academy of Pediatrics Clinical Practice Guideline: Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics 2004; 114: 297\u2013316.","DOI":"10.1542\/peds.114.1.297"},{"issue":"8","key":"BFjp2008211_CR18","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1111\/j.1651-2227.1997.tb08608.x","volume":"86","author":"TW Hansen","year":"1997","unstructured":"Hansen TW . Acute management of extreme neonatal jaundice\u2014the potential benefits of intensified phototherapy and interruption of enterohepatic bilirubin circulation. Acta Paediatr 1997; 86 (8): 843\u2013846.","journal-title":"Acta Paediatr"},{"key":"BFjp2008211_CR19","doi-asserted-by":"publisher","first-page":"e130","DOI":"10.1542\/peds.114.1.e130","volume":"114","author":"S Ip","year":"2004","unstructured":"Ip S, Chung M, Kulig J, O\u2019Brien R, Sege R, Glicken S, et al., Subcommittee on Hyperbilirubinemia. An evidence-based review of important issues concerning neonatal hyperbilirubinemia. Pediatrics 2004; 114: e130\u2013e153.","journal-title":"Pediatrics"},{"issue":"3","key":"BFjp2008211_CR20","doi-asserted-by":"publisher","first-page":"1207","DOI":"10.1542\/peds.2006-0018","volume":"118","author":"TN Raju","year":"2006","unstructured":"Raju TN, Higgins RD, Stark AR, Leveno KJ . Optimizing care and outcome for late-preterm (near-term) infants: a summary of the workshop sponsored by the National Institute of Child Health and Human Development. Pediatrics 2006; 118 (3): 1207\u20131214.","journal-title":"Pediatrics"},{"issue":"11","key":"BFjp2008211_CR21","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1038\/sj.jp.7211153","volume":"24","author":"RH Palmer","year":"2004","unstructured":"Palmer RH, Keren R, Maisels MJ, Yeargin-Allsopp M . National Institute of Child Health and Human Development (NICHD) conference on kernicterus: a population perspective on prevention of kernicterus. J Perinatol 2004; 24 (11): 723\u2013725.","journal-title":"J Perinatol"},{"key":"BFjp2008211_CR22","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1038\/sj.jp.7211124","volume":"24","author":"DK Stevenson","year":"2004","unstructured":"Stevenson DK, Wong RJ, Vreman HJ, McDonagh AF, Maisels MJ, Lightner DA . NICHD Conference on Kernicterus: research on prevention of bilirubin-induced brain injury and kernicterus: bench-to-bedside\u2014diagnostic methods and prevention and treatment strategies. J Perinatol 2004; 24: 521\u2013525.","journal-title":"J Perinatol"},{"issue":"4","key":"BFjp2008211_CR23","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1038\/sj.jp.7211244","volume":"25","author":"SE Sheridan","year":"2005","unstructured":"Sheridan SE . Parents of infants and children with kernicterus. J Perinatol 2005; 25 (4): 227\u2013228.","journal-title":"J Perinatol"},{"key":"BFjp2008211_CR24","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1038\/sj.jp.7211152","volume":"24","author":"VK Bhutani","year":"2004","unstructured":"Bhutani VK, Johnson LH, Maisels MJ, Newman TB, Phibbs C, Stark AR et al. Kernicterus: epidemiological strategies for its prevention through systems-based approaches. J Perinatol 2004; 24: 650\u2013662.","journal-title":"J Perinatol"},{"issue":"1","key":"BFjp2008211_CR25","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1542\/peds.103.1.6","volume":"103","author":"VK Bhutani","year":"1999","unstructured":"Bhutani VK, Johnson L, Sivieri EM . Predictive ability of a pre-discharge hour-specific serum bilirubin for subsequent significant hyperbilirubinemia in healthy term and near-term newborns. Pediatrics 1999; 103 (1): 6\u201314.","journal-title":"Pediatrics"},{"key":"BFjp2008211_CR26","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1542\/peds.108.1.31","volume":"108","author":"DK Stevenson","year":"2001","unstructured":"Stevenson DK, Fanaroff AA, Maisels MJ, Young BW, Wong RJ, Vreman HJ et al. Prediction of hyperbilirubinemia in term and near-term newborn infants. Pediatrics 2001; 108: 31\u201339.","journal-title":"Pediatrics"},{"issue":"4","key":"BFjp2008211_CR27","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1016\/j.pcl.2004.03.011","volume":"51","author":"VK Bhutani","year":"2004","unstructured":"Bhutani VK, Johnson LH, Keren R . Diagnosis and management of hyperbilirubinemia in the term neonate: for a safer first week. Pediatr Clin North Am 2004; 51 (4): 843\u2013861.","journal-title":"Pediatr Clin North Am"},{"key":"BFjp2008211_CR28","unstructured":"Institute of Medicine. To err is human: building a safer health system. 1 November 1999. http:\/\/www.iom.edu\/?id=12735."},{"issue":"31","key":"BFjp2008211_CR29","first-page":"1","volume":"31","author":"Joint Commission Accrediting Hospital Organizations (JCAHO)","year":"2004","unstructured":"Joint Commission Accrediting Hospital Organizations (JCAHO). Revised guidance to help prevent kernicterus. Sentinel Event Alert 2004; 31 (31): 1\u20132.","journal-title":"Sentinel Event Alert"},{"issue":"2","key":"BFjp2008211_CR30","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1053\/j.semperi.2006.04.001","volume":"30","author":"VK Bhutani","year":"2006","unstructured":"Bhutani VK, Johnson L . Kernicterus in late preterm infants cared for as term healthy infants. Semin Perinatol 2006; 30 (2): 89\u201397.","journal-title":"Semin Perinatol"},{"key":"BFjp2008211_CR31","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1111\/j.1651-2227.1983.tb09791.x","volume":"72","author":"F Ebbesen","year":"1983","unstructured":"Ebbesen F, Nyboe J . Postnatal changes in the ability of plasma albumin to bind bilirubin. Acta Paediatr Scand 1983; 72: 665\u2013670.","journal-title":"Acta Paediatr Scand"},{"key":"BFjp2008211_CR32","doi-asserted-by":"publisher","first-page":"1213","DOI":"10.1111\/j.1651-2227.2001.tb01368.x","volume":"89","author":"F Ebbesen","year":"2000","unstructured":"Ebbesen F . Recurrence of kernicterus in term and near-term infants in Denmark. Acta Paediatr 2000; 89: 1213\u20131217.","journal-title":"Acta Paediatr"},{"key":"BFjp2008211_CR33","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1080\/08035250410022170","volume":"94","author":"F Ebbesen","year":"2005","unstructured":"Ebbesen F, Andersson C, Verder H, Grytter C, Pedersen-Bjergaard L, Petersen JR et al. Extreme hyperbilirubinaemia in term and near-term infants in Denmark. Acta Paediatr 2005; 94: 59\u201364.","journal-title":"Acta Paediatr"},{"key":"BFjp2008211_CR34","unstructured":"Manning DJ, Maxwell MJ, Todd PJ, Platt MJ . Prospective surveillance study of severe hyperbilirubinaemia in the newborn in the United Kingdom and Ireland. Arch Dis Child. Fetal Neonatal Ed. Online publication. 0.1136\/adc.2006.105361. http:\/\/fn.bmj.com\/cgi\/rapidpdf\/adc.2006.105361v1."},{"key":"BFjp2008211_CR35","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1503\/cmaj.060328","volume":"175","author":"M Sgro","year":"2006","unstructured":"Sgro M, Campbell D, Shah V . Incidence and causes of severe neonatal hyperbilirubinemia in Canada. CMAJ 2006; 175: 587\u2013590.","journal-title":"CMAJ"},{"issue":"4","key":"BFjp2008211_CR36","first-page":"313","volume":"83","author":"FP Facchini","year":"2007","unstructured":"Facchini FP, Mezzacappa MA, Rosa IR, Mezzacappa Filho F, Aranha-Netto A, Marba ST . Follow-up of neonatal jaundice in term and late premature newborns. J Pediatr (Rio J) 2007; 83 (4): 313\u2013322.","journal-title":"J Pediatr (Rio J)"},{"issue":"4","key":"BFjp2008211_CR37","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1016\/j.jpeds.2006.12.014","volume":"150","author":"M Kaplan","year":"2007","unstructured":"Kaplan M, Bromiker R, Schimmel MS, Algur N, Hammerman C . Evaluation of discharge management in the prediction of hyperbilirubinemia: the Jerusalem experience. J Pediatr 2007; 150 (4): 412\u2013417.","journal-title":"J Pediatr"},{"issue":"4","key":"BFjp2008211_CR38","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1111\/j.1552-6909.2006.00044.x","volume":"35","author":"VK Bhutani","year":"2006","unstructured":"Bhutani VK, Johnson LH, Schwoebel A, Gennaro S . A systems approach for neonatal hyperbilirubinemia in term and near-term newborns. J Obstet Gynecol Neonatal Nurs 2006; 35 (4): 444\u2013455.","journal-title":"J Obstet Gynecol Neonatal Nurs"},{"key":"BFjp2008211_CR39","doi-asserted-by":"publisher","first-page":"e855","DOI":"10.1542\/peds.2005-1338","volume":"117","author":"LD Eggert","year":"2006","unstructured":"Eggert LD, Wiedmeier SE, Wilson J, Christensen RD . The effect of instituting a prehospital-discharge newborn bilirubin screening program in an 18-hospital health system. Pediatrics 2006; 117: e855\u2013e862.","journal-title":"Pediatrics"},{"issue":"1","key":"BFjp2008211_CR40","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.clp.2004.11.002","volume":"32","author":"VK Bhutani","year":"2005","unstructured":"Bhutani VK, Donn SM, Johnson LH . Risk management of severe neonatal hyperbilirubinemia: to prevent kernicterus. Clin Perinatol 2005; 32 (1): 125\u2013139.","journal-title":"Clin Perinatol"},{"key":"BFjp2008211_CR41","unstructured":"Susan E . Sheridan, consumer, Testimony to the National Summit on Medical Errors and Patient Safety Research, Washington, DC, 11 September 2000, www.quic.gov\/summit\/wsheridan.htm (accessed 21 March 2003)."},{"issue":"6 Pt 1","key":"BFjp2008211_CR42","doi-asserted-by":"publisher","first-page":"1303","DOI":"10.1542\/peds.111.6.1303","volume":"111","author":"TB Newman","year":"2003","unstructured":"Newman TB, Liljestrand P, Escobar GJ . Infants with bilirubin levels of 30 mg\/dl or more in a large managed care organization. Pediatrics 2003; 111 (6 Pt 1): 1303\u20131311.","journal-title":"Pediatrics"},{"key":"BFjp2008211_CR43","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1542\/peds.38.4.545","volume":"38","author":"JE Lucey","year":"1966","unstructured":"Lucey JE . Kernicterus: revised concepts of pathogenesis and management. Commentary. Pediatrics 1966; 38: 545\u2013546.","journal-title":"Pediatrics"},{"key":"BFjp2008211_CR44","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1542\/peds.2005-0395","volume":"117","author":"RP Wennberg","year":"2006","unstructured":"Wennberg RP, Ahlfors CE, Bhutani VK, Johnson LH, Shapiro SM . Toward understanding kernicterus: a challenge to improve the management of jaundiced newborns. Pediatrics 2006; 117: 474\u2013485.","journal-title":"Pediatrics"},{"key":"BFjp2008211_CR45","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1542\/peds.114.2.494","volume":"114","author":"C Lannon","year":"2004","unstructured":"Lannon C, Stark AR . Closing the gap between guidelines and practice: ensuring safe and healthy beginnings. Pediatrics 2004; 114: 494\u2013496.","journal-title":"Pediatrics"},{"key":"BFjp2008211_CR46","unstructured":"Center for Disease Control and Prevention. http:\/\/www.cdc.gov\/ncbddd\/dd\/kernichome.htm."},{"key":"BFjp2008211_CR47","unstructured":"Association of Women's Health, Obstetrics and Neonatal Nurses. http:\/\/www.awhonn.org\/awhonn\/product.detail.do?productCode=HNPP-CD-2NDI."},{"key":"BFjp2008211_CR48","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1016\/j.siny.2006.02.002","volume":"11","author":"H Smitherman","year":"2006","unstructured":"Smitherman H, Stark AR, Bhutani VK . Early recognition of neonatal hyperbilirubinemia and its emergent management. Semin Fetal Neonatal Med 2006; 11: 214\u2013224.","journal-title":"Semin Fetal Neonatal Med"},{"key":"BFjp2008211_CR49","unstructured":"California Perinatal Quality Care Collaborative. http:\/\/www.cpqcc.org\/quality_improvement.htm."},{"issue":"1","key":"BFjp2008211_CR50","doi-asserted-by":"publisher","first-page":"e170","DOI":"10.1542\/peds.2006-3499","volume":"121","author":"R Keren","year":"2008","unstructured":"Keren R, Luan X, Friedman S, Saddlemire S, Cnaan A, Bhutani VK . A comparison of alternative risk-assessment strategies for predicting significant neonatal hyperbilirubinemia in term and near-term infants. Pediatrics 2008; 121 (1): e170\u2013e179.","journal-title":"Pediatrics"},{"issue":"Suppl 1","key":"BFjp2008211_CR51","doi-asserted-by":"publisher","first-page":"S58","DOI":"10.1038\/jp.2008.217","volume":"29","author":"C Lazarus","year":"2009","unstructured":"Lazarus C, Avchen RN . Neonatal hyperbilirubinemia management: a model for change. J Perinatol 2009; 29 (Suppl 1): S58\u2013S60.","journal-title":"J Perinatol"},{"issue":"Suppl 1","key":"BFjp2008211_CR52","doi-asserted-by":"publisher","first-page":"S53","DOI":"10.1038\/jp.2008.215","volume":"29","author":"AR Stark","year":"2009","unstructured":"Stark AR, Lannon CM . Systems changes to prevent severe hyperbilirubinemia and promote breastfeeding: pilot approaches. J Perinatol 2009; 29 (Suppl 1): S53\u2013S57.","journal-title":"J Perinatol"}],"container-title":["Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/jp2008211.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/jp2008211","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/jp2008211.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T12:14:55Z","timestamp":1647605695000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/jp2008211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1,28]]},"references-count":52,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["BFjp2008211"],"URL":"https:\/\/doi.org\/10.1038\/jp.2008.211","relation":{},"ISSN":["0743-8346","1476-5543"],"issn-type":[{"value":"0743-8346","type":"print"},{"value":"1476-5543","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,1,28]]},"assertion":[{"value":"28 January 2009","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}