{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T07:10:07Z","timestamp":1771571407944,"version":"3.50.1"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2010,3,30]],"date-time":"2010-03-30T00:00:00Z","timestamp":1269907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2010,3,30]],"date-time":"2010-03-30T00:00:00Z","timestamp":1269907200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Perinatol"],"published-print":{"date-parts":[[2010,4]]},"DOI":"10.1038\/jp.2009.140","type":"journal-article","created":{"date-parts":[[2010,3,30]],"date-time":"2010-03-30T07:33:50Z","timestamp":1269934430000},"page":"291-294","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Prenatal closure of the ductus arteriosus and maternal ingestion of anthocyanins"],"prefix":"10.1038","volume":"30","author":[{"given":"V","family":"Kapadia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Embers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Wells","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Lemler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C R","family":"Rosenfeld","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,3,30]]},"reference":[{"key":"BFjp2009140_CR1","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1345\/aph.1G428","volume":"40","author":"G Koren","year":"2006","unstructured":"Koren G, Florescu A, Costei AM, Boskovic R, Moretti ME . Nonsteroidal antiinflammatory drugs during third trimester and the risk of premature closure of the ductus arteriosus: a meta-analysis. Ann Pharmacother 2006; 40: 824\u2013829.","journal-title":"Ann Pharmacother"},{"key":"BFjp2009140_CR2","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1161\/01.CIR.60.2.360","volume":"60","author":"DL Levin","year":"1979","unstructured":"Levin DL, Mills LJ, Weinberg AG . Hemodynamic, pulmonary vascular, and myocardial abnormalities secondary to pharmacologic constriction of the fetal ductus arteriosus. A possible mechanism for persistent pulmonary hypertension and transient tricuspid insufficiency in the newborn infant. Circulation 1979; 60: 360\u2013364.","journal-title":"Circulation"},{"key":"BFjp2009140_CR3","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1016\/S0002-9378(96)70317-4","volume":"174","author":"G Hofstadler","year":"1996","unstructured":"Hofstadler G, Tulzer G, Altmann R, Schitt K, Danford D, Huhta JC . Spontaneous closure of the human fetal ductus arteriosus\u2014a cause of fetal congestive heart failure. Am J Obstet Gynecol 1996; 174: 879\u2013883.","journal-title":"Am J Obstet Gynecol"},{"key":"BFjp2009140_CR4","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1016\/S0022-3476(78)80453-3","volume":"92","author":"DL Levin","year":"1978","unstructured":"Levin DL, Fixler DE, Morriss FC, Tyson J . Morphologic analysis of the pulmonary vascular bed in infants exposed in utero to prostaglandin synthetase inhibitors. J Pediatr 1978; 92: 478\u2013483.","journal-title":"J Pediatr"},{"key":"BFjp2009140_CR5","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1016\/S0146-0005(97)80005-5","volume":"21","author":"RH Steinhorn","year":"1997","unstructured":"Steinhorn RH, Morin 3rd FC, Fineman JR . Models of persistent pulmonary hypertension of the newborn (PPHN) and the role of cyclic guanosine monophosphate (GMP) in pulmonary vasorelaxation. Semin Perinatol 1997; 21: 393\u2013408.","journal-title":"Semin Perinatol"},{"key":"BFjp2009140_CR6","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1203\/00006450-199805000-00012","volume":"43","author":"RI Clyman","year":"1998","unstructured":"Clyman RI, Waleh N, Black SM, Riemer RK, Mauray F, Chen YQ . Regulation of ductus arteriosus patency by nitric oxide in fetal lambs: the role of gestation, oxygen tension, and vasa vasorum. Pediatr Res 1998; 43: 633\u2013644.","journal-title":"Pediatr Res"},{"key":"BFjp2009140_CR7","doi-asserted-by":"publisher","first-page":"8326","DOI":"10.1021\/jf8016157","volume":"56","author":"GS Jensen","year":"2008","unstructured":"Jensen GS, Wu X, Patterson KM, Barnes J, Carter SG, Scherwitz L, Beaman R, Endres JR, Schauss AG . In vitro and in vivo antioxidant and anti-inflammatory capacities of an antioxidant-rich fruit and berry juice blend. Results of a pilot and randomized, double-blinded, placebo-controlled, crossover study. J Agric Food Chem 2008; 56: 8326\u20138333.","journal-title":"J Agric Food Chem"},{"key":"BFjp2009140_CR8","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/j.bcp.2005.05.003","volume":"70","author":"DX Hou","year":"2005","unstructured":"Hou DX, Yanagita T, Uto T, Masuzaki S, Fujii M . Anthocyanidins inhibit cyclooxygenase-2 expression in LPS-evoked macrophages: structure-activity relationship and molecular mechanisms involved. Biochem Pharmacol 2005; 70: 417\u2013425.","journal-title":"Biochem Pharmacol"},{"key":"BFjp2009140_CR9","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1016\/j.lfs.2008.05.017","volume":"83","author":"Q Wang","year":"2008","unstructured":"Wang Q, Xia M, Liu C, Guo H, Ye Q, Hu Y et al. Cyanidin-3-O-beta-glucoside inhibits iNOS and COX-2 expression by inducing liver X receptor alpha activation in THP-1 macrophages. Life Sci 2008; 83: 176\u2013184.","journal-title":"Life Sci"},{"key":"BFjp2009140_CR10","first-page":"45","volume":"152","author":"T Dokoupil","year":"2008","unstructured":"Dokoupil T . A drink's purple reign. Newsweek 2008; 152: 45.","journal-title":"Newsweek"},{"key":"BFjp2009140_CR11","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1159\/000092870","volume":"89","author":"RI Clyman","year":"2006","unstructured":"Clyman RI . Mechanisms regulating the ductus arteriosus. Biol Neonate 2006; 89: 330\u2013335.","journal-title":"Biol Neonate"},{"key":"BFjp2009140_CR12","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1203\/00006450-197204000-00004","volume":"6","author":"DM Mcmurphy","year":"1972","unstructured":"Mcmurphy DM, Heymann MA, Rudolph AM, Melmon KL . Developmental changes in constriction of the ductus arteriosus: responses to oxygen and vasoactive agents in the isolated ductus arteriosus of the fetal lamb. Pediatr Res 1972; 6: 231\u2013238.","journal-title":"Pediatr Res"},{"key":"BFjp2009140_CR13","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/0090-6980(78)90028-X","volume":"16","author":"RI Clyman","year":"1978","unstructured":"Clyman RI, Mauray F, Roman C, Rudolph AM . PGE2 is a more potent vasodilator of the lamb ductus arteriosus than is either PGI2 or 6 keto PGF1alpha. Prostaglandins 1978; 16: 259\u2013264.","journal-title":"Prostaglandins"},{"key":"BFjp2009140_CR14","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1055\/s-2007-994128","volume":"14","author":"SD Leal","year":"1997","unstructured":"Leal SD, Cavalle-Garrido T, Ryan G, Farine D, Helibut M, Smallhorn JF . Isolated ductal closure in utero diagnosed by fetal echocardiography. Am J Perinatol 1997; 14: 205\u2013210.","journal-title":"Am J Perinatol"},{"key":"BFjp2009140_CR15","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1161\/01.HYP.0000135868.38343.c6","volume":"44","author":"JW Xu","year":"2004","unstructured":"Xu JW, Ikeda K, Yamori Y . Upregulation of endothelial nitric oxide synthase by cyanidin-3-glucoside, a typical anthocyanin pigment. Hypertension 2004; 44: 217\u2013222.","journal-title":"Hypertension"}],"container-title":["Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/jp2009140.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/jp2009140","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/jp2009140.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T13:10:40Z","timestamp":1647609040000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/jp2009140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3,30]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,4]]}},"alternative-id":["BFjp2009140"],"URL":"https:\/\/doi.org\/10.1038\/jp.2009.140","relation":{},"ISSN":["0743-8346","1476-5543"],"issn-type":[{"value":"0743-8346","type":"print"},{"value":"1476-5543","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,3,30]]},"assertion":[{"value":"27 April 2009","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 July 2009","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 August 2009","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 March 2010","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}