{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T14:52:45Z","timestamp":1778943165737,"version":"3.51.4"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T00:00:00Z","timestamp":1238630400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T00:00:00Z","timestamp":1238630400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Perinatol"],"published-print":{"date-parts":[[2009,6]]},"DOI":"10.1038\/jp.2009.36","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T08:19:27Z","timestamp":1238660367000},"page":"433-437","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Early amino acids and the metabolic response of ELBW infants (\u2a7d1000\u2009g) in three time periods"],"prefix":"10.1038","volume":"29","author":[{"given":"P G","family":"Radmacher","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S L","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D H","family":"Adamkin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,4,2]]},"reference":[{"issue":"1","key":"BFjp200936_CR1","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/S0095-5108(05)70014-2","volume":"27","author":"PJ Thureen","year":"2000","unstructured":"Thureen PJ, Hay Jr WW . Intravenous nutrition and postnatal growth of the micropremie. Clin Perinatol 2000; 27 (1): 197\u2013219.","journal-title":"Clin Perinatol"},{"key":"BFjp200936_CR2","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/S0095-5108(18)30299-9","volume":"22","author":"PW Aldoretta","year":"1995","unstructured":"Aldoretta PW, Hay Jr WW . Metabolic substrates for fetal energy metabolism and growth. Clin Perinatol 1995; 22: 15\u201336.","journal-title":"Clin Perinatol"},{"key":"BFjp200936_CR3","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1016\/S0022-3476(71)80396-7","volume":"79","author":"EL Gresham","year":"1971","unstructured":"Gresham EL, Simons PS, Battaglia FC . Maternal-fetal urea concentration difference in man: metabolic significance. J Pediatr 1971; 79: 809\u2013811.","journal-title":"J Pediatr"},{"issue":"6","key":"BFjp200936_CR4","doi-asserted-by":"publisher","first-page":"1428","DOI":"10.1172\/JCI108598","volume":"58","author":"JA Lemons","year":"1976","unstructured":"Lemons JA, Adcock EW, Jones MDJ, Naughton MA, Meschia G, Battaglia FC . Umbilical uptake of amino acids in the unstressed fetal lamb. J Clin Invest 1976; 58 (6): 1428\u20131434.","journal-title":"J Clin Invest"},{"key":"BFjp200936_CR5","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/0026-0495(87)90062-X","volume":"36","author":"LC van Veen","year":"1987","unstructured":"van Veen LC, Teng C, Hay Jr WW, Meschia G, Battaglia FC . Leucine disposal and oxidation rates in the fetal lamb. Metabolism 1987; 36: 48\u201353.","journal-title":"Metabolism"},{"key":"BFjp200936_CR6","first-page":"133","volume-title":"Protein Metabolism During Infancy","author":"S Kashyap","year":"1993","unstructured":"Kashyap S, Heird WC . Protein requirements of low birthweight, very low birthweight, and small for gestational age infants. In: Raiha N (ed). Protein Metabolism During Infancy. Raven Press: New York, 1993 p 133."},{"key":"BFjp200936_CR7","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1016\/S0022-3476(89)80858-3","volume":"115","author":"AJ Rivera","year":"1989","unstructured":"Rivera AJ, Bell EF, Stegink LD, Ziegler E . Plasma amino acid profiles during the first three days of life in infants with respiratory distress syndrome: effect of parenteral amino acid supplementation. J Pediatr 1989; 115: 465\u2013468.","journal-title":"J Pediatr"},{"key":"BFjp200936_CR8","doi-asserted-by":"publisher","first-page":"1362","DOI":"10.1136\/adc.64.10_Spec_No.1362","volume":"64","author":"J Saini","year":"1989","unstructured":"Saini J, MacMahon P, Morgan JB, Kovar IZ . Early parenteral feeding of amino acids. Arch Dis Child 1989; 64: 1362\u20131366.","journal-title":"Arch Dis Child"},{"issue":"9","key":"BFjp200936_CR9","doi-asserted-by":"publisher","first-page":"e45","DOI":"10.1542\/pir.20-9-e45","volume":"20","author":"PJ Thureen","year":"1999","unstructured":"Thureen PJ . Early aggressive nutrition in the neonate. Pediatr Rev 1999; 20 (9): e45\u2013e55.","journal-title":"Pediatr Rev"},{"issue":"5","key":"BFjp200936_CR10","doi-asserted-by":"publisher","first-page":"1128","DOI":"10.1093\/ajcn\/68.5.1128","volume":"68","author":"PJ Thureen","year":"1998","unstructured":"Thureen PJ, Anderson AH, Baron KA, Melara DL, Hay Jr WW, Fennessey PV . Protein balance in the first week of life in ventilated neonates receiving parenteral nutrition.[erratum appears in Am J Clin Nutr 1999 Aug;70 (2):303]. Am J Clin Nutr 1998; 68 (5): 1128\u20131135.","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"BFjp200936_CR11","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1203\/00006450-200301000-00008","volume":"53","author":"PJ Thureen","year":"2003","unstructured":"Thureen PJ, Melara D, Fennessey PV, Hay Jr WW . Effect of low versus high intravenous amino acid intake on very low birth weight infants in the early neonatal period. Pediatr Res 2003; 53 (1): 24\u201332.","journal-title":"Pediatr Res"},{"issue":"4","key":"BFjp200936_CR12","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1016\/j.jpeds.2005.05.038","volume":"147","author":"FWJ te Braake","year":"2005","unstructured":"te Braake FWJ, van den Akker CHP, Wattimena DJL, Huijmans JGM, van Goudoever JB . Amino acid administration to premature infants directly after birth.[see comment]. J Pediatr 2005; 147 (4): 457\u2013461.","journal-title":"J Pediatr"},{"issue":"2","key":"BFjp200936_CR13","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1038\/sj.jp.7211215","volume":"25","author":"E Ridout","year":"2005","unstructured":"Ridout E, Melara D, Rottinghaus S, Thureen PJ . Blood urea nitrogen concentration as a marker of amino-acid intolerance in neonates with birthweight less than 1250\u2009g. J Perinatol 2005; 25 (2): 130\u2013133.","journal-title":"J Perinatol"},{"key":"BFjp200936_CR14","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1067\/mpd.2001.109608","volume":"138","author":"DK Richardson","year":"2001","unstructured":"Richardson DK, Corcoran JD, Escobar GJ, Lee SK . SNAP-II and SNAPPE-II: simplified newborn illness severity and mortality risk scores. J Pediatr 2001; 138: 92\u2013100.","journal-title":"J Pediatr"},{"issue":"1","key":"BFjp200936_CR15","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1097\/00075197-199801000-00012","volume":"1","author":"WC Heird","year":"1998","unstructured":"Heird WC . Amino acids in pediatric and neonatal nutrition. Current Opinion in Clinical Nutrition and Metabolic Care 1998; 1 (1): 73\u201378.","journal-title":"Current Opinion in Clinical Nutrition and Metabolic Care"},{"issue":"8","key":"BFjp200936_CR16","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1038\/sj.jp.7211114","volume":"24","author":"HM Ibrahim","year":"2004","unstructured":"Ibrahim HM, Jeroudi MA, Baier RJ, Dhanireddy R, Krouskop RW . Aggressive early total parental nutrition in low-birth-weight infants. J Perinatol 2004; 24 (8): 482\u2013486.","journal-title":"J Perinatol"},{"issue":"5","key":"BFjp200936_CR17","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1038\/sj.jp.7210550","volume":"21","author":"S Kalhan","year":"2001","unstructured":"Kalhan S, Bier D, Yaffe S, Catz C, Grave G . Protein\/amino acid metabolism and nutrition in very low birth weight infants. J Perinatol 2001; 21 (5): 320\u2013323.","journal-title":"J Perinatol"},{"issue":"8","key":"BFjp200936_CR18","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1007\/s00431-006-0124-1","volume":"165","author":"R Lenclen","year":"2006","unstructured":"Lenclen R, Crauste-Manciet S, Narcy P, Boukhouna S, Geffray A, Guerrault M-N et al. Assessment of implementation of a standardized parenteral formulation for early nutritional support of very preterm infants. Eur J Pediatr 2006; 165 (8): 512\u2013518.","journal-title":"Eur J Pediatr"},{"issue":"6 Suppl","key":"BFjp200936_CR19","doi-asserted-by":"publisher","first-page":"1566S","DOI":"10.1093\/jn\/134.6.1566S","volume":"134","author":"PB Pencharz","year":"2004","unstructured":"Pencharz PB, Ball RO . Amino acid needs for early growth and development. J Nutr 2004; 134 (6 Suppl): 1566S\u20131568S.","journal-title":"J Nutr"},{"issue":"5","key":"BFjp200936_CR20","doi-asserted-by":"publisher","first-page":"95R","DOI":"10.1203\/01.PDR.0000160434.69916.34","volume":"57","author":"PJ Thureen","year":"2005","unstructured":"Thureen PJ, Heird WC . Protein and energy requirements of the preterm\/low birth weight (LBW) infant. Pediatr Res 2005; 57 (5): 95R\u201398R.","journal-title":"Pediatr Res"},{"key":"BFjp200936_CR21","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/S0022-3476(81)80975-4","volume":"99","author":"SH Zlotkin","year":"1981","unstructured":"Zlotkin SH, Bryan MH, Anderson GH . Intravenous nitrogen and energy intakes required to duplicate in utero nitrogren accretion in prematurely born human infants. J Pediatr 1981; 99: 115\u2013120.","journal-title":"J Pediatr"},{"key":"BFjp200936_CR22","doi-asserted-by":"publisher","first-page":"C106","DOI":"10.1152\/ajpcell.1981.241.3.C106","volume":"241","author":"BM Eaton","year":"1982","unstructured":"Eaton BM, Yudilevich DL . Uptake and asymmetric efflux of amino acids at maternal and fetal sides of placenta. Am J Physiol 1982; 241: C106\u2013C112.","journal-title":"Am J Physiol"},{"key":"BFjp200936_CR23","first-page":"E320","volume":"240","author":"PR Meier","year":"1981","unstructured":"Meier PR, Peterson RG, Bonds DR, Meschia G, Battaglia FC . Rates of protein synthesis and turnover in fetal life. Am J Physiol 1981; 240: E320\u2013E324.","journal-title":"Am J Physiol"},{"key":"BFjp200936_CR24","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.jpeds.2007.06.002","volume":"152","author":"DT Robinson","year":"2008","unstructured":"Robinson DT, Ehrenkranz RA . Parenteral nutrition-associated cholestasis in small for gestational age infants. J Pediatr 2008; 152: 59\u201362.","journal-title":"J Pediatr"},{"key":"BFjp200936_CR25","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1038\/sj.jp.7211137","volume":"24","author":"MC Baserga","year":"2004","unstructured":"Baserga MC, Sola A . Intrauterine growth restriciton impacts tolerance to total parenteral nutrition in extremely low birth weight infants. J Perinatol 2004; 24: 476\u2013481.","journal-title":"J Perinatol"},{"key":"BFjp200936_CR26","first-page":"41","volume":"81","author":"WC Heird","year":"1988","unstructured":"Heird WC, Hay Jr WW, Helms RA, Storm MC, Kashyap S, Dell RB . Pediatrics parenteral amino acid mixture in low birth weight infants. Pediatrics 1988; 81: 41\u201350.","journal-title":"Pediatrics"},{"key":"BFjp200936_CR27","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1016\/S0022-3476(87)80519-X","volume":"110","author":"RA Helms","year":"1987","unstructured":"Helms RA, Christensen ML, Mauer EC, Storm MC . Comparison of pediatric versus standard amino acid formulation in preterm neonates requiring parenteral nutrition. J Pediatr 1987; 110: 466\u2013470.","journal-title":"J Pediatr"},{"key":"BFjp200936_CR28","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1203\/00006450-199302000-00003","volume":"33","author":"AJ Rivera","year":"1993","unstructured":"Rivera AJ, Bell EF, Bier D . Effect of intravenous amino acids on protein metabolism of preterm infants during the first three days of life. Pediatr Res 1993; 33: 106\u2013111.","journal-title":"Pediatr Res"},{"key":"BFjp200936_CR29","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1016\/S0022-3476(95)70083-8","volume":"127","author":"JB Van Goudoever","year":"1995","unstructured":"Van Goudoever JB, Colen T, Wattimena JLD, Huijmans JGM, Carnielli VP, Sauer PJJ . Immedidate commencement of amino acid supplementation in preterm infants: effect on serum amino acid concentrations and protein kinetics on the first day of life. J Pediatr 1995; 127: 458\u2013465.","journal-title":"J Pediatr"}],"container-title":["Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/jp200936.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/jp200936","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/jp200936.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T11:41:39Z","timestamp":1647603699000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/jp200936"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4,2]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,6]]}},"alternative-id":["BFjp200936"],"URL":"https:\/\/doi.org\/10.1038\/jp.2009.36","relation":{},"ISSN":["0743-8346","1476-5543"],"issn-type":[{"value":"0743-8346","type":"print"},{"value":"1476-5543","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4,2]]},"assertion":[{"value":"4 November 2008","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 January 2009","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 February 2009","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 April 2009","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}