{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T23:05:33Z","timestamp":1790982333988,"version":"4.1.0"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2010,7,29]],"date-time":"2010-07-29T00:00:00Z","timestamp":1280361600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2010,7,29]],"date-time":"2010-07-29T00:00:00Z","timestamp":1280361600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Perinatol"],"published-print":{"date-parts":[[2011,3]]},"DOI":"10.1038\/jp.2010.86","type":"journal-article","created":{"date-parts":[[2010,7,29]],"date-time":"2010-07-29T10:00:32Z","timestamp":1280397632000},"page":"193-198","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Hypernatremia and grade III\/IV intraventricular hemorrhage among extremely low birth weight infants"],"prefix":"10.1038","volume":"31","author":[{"given":"W-H","family":"Lim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Lien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M-C","family":"Chiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R-H","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J-J","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S-M","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J-F","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P-H","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,7,29]]},"reference":[{"key":"BFjp201086_CR1","first-page":"428","volume-title":"Neurology of the Newborn","author":"JJ Volpe","year":"2001","unstructured":"Volpe JJ . Intracranial hemorrhage: Germinal matrix-intraventricular hemorrhage In: Volpe JJ (ed) Neurology of the Newborn. 4th edn. WB Saunders: Philadelphia, 2001 pp 428."},{"key":"BFjp201086_CR2","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.ajog.2006.09.014","volume":"196","author":"AA Fanaroff","year":"2007","unstructured":"Fanaroff AA, Stoll BJ, Wright LL, Carlo WA, Ehrenkranz RA, Stark AR, et al., NICHD Neonatal Research Network. Trends in neonatal morbidity and mortality for very low birthweight infants. Am J Obstet Gynecol 2007; 196: 147.","journal-title":"Am J Obstet Gynecol"},{"key":"BFjp201086_CR3","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1136\/fn.86.2.F86","volume":"86","author":"AM Heuchan","year":"2002","unstructured":"Heuchan AM, Evans N, Henderson Smart DJ, Simpson JM . Perinatal risk factors for major intraventricular haemorrhage in the Australian and New Zealand Neonatal Network 1995\u201397. Arch Dis Child Fetal Neonatal Ed 2002; 86: 86\u201390.","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"BFjp201086_CR4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0378-3782(95)01692-9","volume":"44","author":"B Vohr","year":"1996","unstructured":"Vohr B, Ment LR . Intraventricular hemorrhage in the preterm infant. Early Hum Dev 1996; 44: 1\u201316.","journal-title":"Early Hum Dev"},{"key":"BFjp201086_CR5","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1542\/peds.111.5.e590","volume":"111","author":"N Linder","year":"2003","unstructured":"Linder N, Haskin O, Levit O, Klinger G, Prince T, Naor N et al. Risk factors for intraventricular haemorrhage in very low birth weight premature infants: a retrospective case-control study. Pediatrics 2003; 111: 590\u2013595.","journal-title":"Pediatrics"},{"issue":"12","key":"BFjp201086_CR6","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1111\/j.1440-1754.2006.00975.x","volume":"42","author":"Z Gawlowski","year":"2006","unstructured":"Gawlowski Z, Aladangady N, Coen PG . Hypernatraemia in preterm infants born at less than 27 weeks gestation. J Paediatr Child Health 2006; 42 (12): 771\u2013774.","journal-title":"J Paediatr Child Health"},{"key":"BFjp201086_CR7","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1016\/S0022-3476(78)80282-0","volume":"92","author":"LA Papile","year":"1978","unstructured":"Papile LA, Burstein J, Burstein R, Koffler H . Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1500 gm. J Pediatr 1978; 92: 529\u2013534.","journal-title":"J Pediatr"},{"key":"BFjp201086_CR8","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1136\/fn.87.3.F158","volume":"87","author":"IA Laing","year":"2002","unstructured":"Laing IA, Wong CM . Hypernatraemia in the first few days: is the incidence rising? Arch Dis Child Fetal Neonatal Ed 2002; 87: 158\u2013162.","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"BFjp201086_CR9","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1016\/S0022-3476(82)80078-4","volume":"101","author":"JM Lorenz","year":"1982","unstructured":"Lorenz JM, Kleinman LI, Kotagal UR, Reller MD . Water balance in very low birth weight infants: relationship to water and sodium intake and effect on outcome. J Pediatr 1982; 101: 423\u2013432.","journal-title":"J Pediatr"},{"key":"BFjp201086_CR10","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1136\/adc.59.5.423","volume":"59","author":"L Rees","year":"1984","unstructured":"Rees L, Shaw JCL, Brook CGD, Forsling ML . Hyponatraemia in the first week of life in preterm infants: part II Sodium and water balance. Arch Dis Child 1984; 59: 423\u2013429.","journal-title":"Arch Dis Child"},{"key":"BFjp201086_CR11","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1136\/adc.2001.004275","volume":"89","author":"N Modi","year":"2004","unstructured":"Modi N . Management of fluid balance in the very immature neonate. Arch Dis Child Fetal Neonatal Ed 2004; 89: 108\u2013111.","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"BFjp201086_CR12","first-page":"484","volume":"96","author":"JM Lorenz","year":"1995","unstructured":"Lorenz JM, Kleinman LI, Ahmed G, Markarian K . Phases of fluid and electrolyte homeostasis in the extremely low birth weight infant. Pediatrics 1995; 96: 484\u2013489.","journal-title":"Pediatrics"},{"key":"BFjp201086_CR13","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/S0095-5108(18)30485-8","volume":"19","author":"SG Schaffer","year":"1992","unstructured":"Schaffer SG, Weismann DN . Fluid requirements in the preterm infant. Clin Perinatol 1992; 19: 233\u2013250.","journal-title":"Clin Perinatol"},{"key":"BFjp201086_CR14","first-page":"349","volume":"11","author":"A Takaku","year":"1979","unstructured":"Takaku A, Shindo K, Tanaka S, Mori T, Suzuki J . Fluid and electrolyte disturbances in patients with intracranial aneurysms. Surg Neuro 1979; 11: 349\u2013356.","journal-title":"Surg Neuro"},{"key":"BFjp201086_CR15","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1097\/00006123-200204000-00012","volume":"50","author":"AI Qureshi","year":"2002","unstructured":"Qureshi AI, Suri MF, Sung GY, Straw RN, Yahia AM, Saad M et al. Prognostic significance of hypernatremia and hyponatremia among patients with aneurysmal subarachnoid hemorrhage. Neurosurgery 2002; 50: 749\u2013756.","journal-title":"Neurosurgery"},{"key":"BFjp201086_CR16","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1016\/S0749-0704(18)30514-1","volume":"3","author":"MA Geheb","year":"1987","unstructured":"Geheb MA . Clinical approach to the hyperosmolar patient. Crit Care Clin 1987; 3: 797\u2013815.","journal-title":"Crit Care Clin"},{"key":"BFjp201086_CR17","doi-asserted-by":"publisher","first-page":"1260","DOI":"10.1056\/NEJM199511093331906","volume":"333","author":"ML McManus","year":"1995","unstructured":"McManus ML, Churchwell KB, Strange K . Regulation of cell volume in health and disease. N Engl J Med 1995; 333: 1260\u20131266.","journal-title":"N Engl J Med"},{"key":"BFjp201086_CR18","first-page":"522","volume":"253","author":"HF Cserr","year":"1987","unstructured":"Cserr HF, DePasquale M, Patlak CS . Regulation of brain water and electrolytes during acute hyperosmolality in rats. Am J Physiol 1987; 253: 522\u2013529.","journal-title":"Am J Physiol"},{"key":"BFjp201086_CR19","doi-asserted-by":"publisher","first-page":"1427","DOI":"10.1172\/JCI114587","volume":"85","author":"YH Lien","year":"1990","unstructured":"Lien YH, Shapiro JI, Chan L . Effects of hypernatremia on organic brain osmoles. J Clin Invest 1990; 85: 1427\u20131435.","journal-title":"J Clin Invest"},{"key":"BFjp201086_CR20","doi-asserted-by":"publisher","first-page":"1493","DOI":"10.1056\/NEJM200005183422006","volume":"342","author":"HJ Adrogu\u00e9","year":"2000","unstructured":"Adrogu\u00e9 HJ, Madias NE . Hypernatremia. N Engl J Med 2000; 342: 1493\u20131499.","journal-title":"N Engl J Med"},{"key":"BFjp201086_CR21","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1542\/peds.2008-3415","volume":"124","author":"L Baraton","year":"2009","unstructured":"Baraton L, Ancel PY, Flamant C, Orsonneau JL . Impact of changes in serum sodium levels on 2-year neurologic outcomes for very preterm neonates. Pediatrics 2009; 124: 655\u2013661.","journal-title":"Pediatrics"},{"key":"BFjp201086_CR22","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1097\/01.PCC.0000192341.67078.61","volume":"7","author":"JA Tioseco","year":"2006","unstructured":"Tioseco JA, Aly H, Essers J, Patel K, El-Mohandes AA . Male sex and intraventricular hemorrhage. Pediatr Crit Care Med 2006; 7: 40\u201344.","journal-title":"Pediatr Crit Care Med"},{"key":"BFjp201086_CR23","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1016\/j.genm.2009.06.001","volume":"6","author":"E Cuestas","year":"2009","unstructured":"Cuestas E, Bas J, Pautasso J . Sex differences in intraventricular hemorrhage rates among very low birth weight newborns. Gend Med 2009; 6: 376\u2013382.","journal-title":"Gend Med"},{"key":"BFjp201086_CR24","doi-asserted-by":"publisher","first-page":"219","DOI":"10.3171\/jns.1982.57.2.0219","volume":"57","author":"LR Ment","year":"1982","unstructured":"Ment LR, Stewart WB, Duncan CC, Lambrecht R . Beagle puppy model of intraventricular hemorrhage. J Neurosurg 1982; 57: 219\u2013223.","journal-title":"J Neurosurg"},{"key":"BFjp201086_CR25","doi-asserted-by":"publisher","first-page":"1353","DOI":"10.1056\/NEJM198505233122104","volume":"312","author":"JM Perlman","year":"1985","unstructured":"Perlman JM, Goodman S, Kreusser KL, Volpe JJ . Reduction in intraventricular hemorrhage by elimination of fluctuating cerebral blood-flow velocity in preterm infants with respiratory distress syndrome. N Engl J Med 1985; 312: 1353\u20131357.","journal-title":"N Engl J Med"},{"key":"BFjp201086_CR26","first-page":"831","volume":"80","author":"DC Shaver","year":"1992","unstructured":"Shaver DC, Bada HS, Korones SB, Anderson GD, Wong SP, Arheart KL . Early and late intraventricular hemorrhage: the role of obstetric factors. Obstet Gynecol 1992; 80: 831\u2013837.","journal-title":"Obstet Gynecol"},{"key":"BFjp201086_CR27","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1097\/01.AOG.0000154156.51578.50","volume":"105","author":"R Deulofeut","year":"2005","unstructured":"Deulofeut R, Sola A, Lee B, Buchter S, Rahman M, Rogido M et al. The impact of vaginal delivery in premature infants weighing less than 1251 grams. Obstet Gynecol 2005; 105: 525.","journal-title":"Obstet Gynecol"},{"key":"BFjp201086_CR28","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1016\/0002-9378(95)90001-2","volume":"172","author":"LR Ment","year":"1995","unstructured":"Ment LR, Oh W, Ehrenkranz RA, Philip AG, Duncan CC, Makuch RW et al. Antenatal steroids, delivery mode, and intraventricular hemorrhage in preterm infants. Am J Obstet Gynecol 1995; 172: 795\u2013800.","journal-title":"Am J Obstet Gynecol"},{"key":"BFjp201086_CR29","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1097\/AOG.0b013e31817cfdf1","volume":"112","author":"A Riskin","year":"2008","unstructured":"Riskin A, Riskin-Mashiah S, Bader D, Kugelman A, Lerner-Geva L, Boyko V et al. Delivery mode and severe intraventricular hemorrhage in single, very low birth weight, vertex infants. Obstet Gynecol 2008; 112: 21.","journal-title":"Obstet Gynecol"},{"key":"BFjp201086_CR30","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1542\/peds.112.1.33","volume":"112","author":"DA Osborn","year":"2003","unstructured":"Osborn DA, Evans N, Kluckow M . Hemodynamic and antecedent risk factors of early and late periventricular\/intraventricular hemorrhage in premature infants. Pediatrics 2003; 112: 33\u201339.","journal-title":"Pediatrics"},{"key":"BFjp201086_CR31","doi-asserted-by":"publisher","first-page":"F188","DOI":"10.1136\/fn.82.3.F188","volume":"82","author":"M Kluckow","year":"2000","unstructured":"Kluckow M, Evans N . Low superior vena cava flow and intraventricular haemorrhage in preterm infants. Arch Dis Child 2000; 82: F188\u2013F194.","journal-title":"Arch Dis Child"},{"key":"BFjp201086_CR32","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1038\/sj.jp.7211399","volume":"25","author":"S Sarkar","year":"2005","unstructured":"Sarkar S, Kaplan C, Wiswell TE, Spitzer AR . Histological chorioamnionitis and the risk of early intraventricular hemorrhage in infants born <28 weeks gestation. J Perinatol 2005; 25: 749\u2013752.","journal-title":"J Perinatol"},{"key":"BFjp201086_CR33","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1080\/14767050701580515","volume":"20","author":"R Rocha","year":"2007","unstructured":"Rocha R, Proen\u00e7a E, Quintas C, Rodrigues T, Guimar\u00e3es H . Chorioamnionitis and brain damage in the preterm newborn. J Matern Fetal Neonatal Med 2007; 20: 745\u2013749.","journal-title":"J Matern Fetal Neonatal Med"}],"container-title":["Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/jp201086.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/jp201086","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/jp201086.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T12:14:36Z","timestamp":1647605676000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/jp201086"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7,29]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,3]]}},"alternative-id":["BFjp201086"],"URL":"https:\/\/doi.org\/10.1038\/jp.2010.86","relation":{},"ISSN":["0743-8346","1476-5543"],"issn-type":[{"value":"0743-8346","type":"print"},{"value":"1476-5543","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7,29]]},"assertion":[{"value":"22 February 2010","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 June 2010","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 June 2010","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 July 2010","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}