{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T20:29:55Z","timestamp":1790195395009,"version":"4.1.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2011,5,19]],"date-time":"2011-05-19T00:00:00Z","timestamp":1305763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2011,5,19]],"date-time":"2011-05-19T00:00:00Z","timestamp":1305763200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Perinatol"],"published-print":{"date-parts":[[2012,2]]},"DOI":"10.1038\/jp.2011.68","type":"journal-article","created":{"date-parts":[[2011,5,19]],"date-time":"2011-05-19T08:56:49Z","timestamp":1305795409000},"page":"132-138","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":146,"title":["Outcomes of preterm infants <29 weeks gestation over 10-year period in Canada: a cause for concern?"],"prefix":"10.1038","volume":"32","author":[{"given":"P S","family":"Shah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Sankaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Aziz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A C","family":"Allen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Seshia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Ohlsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S K","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Canadian Neonatal Network","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoo K","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakesh S","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne","family":"Andrews","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Barrington","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy","family":"Yee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Bullied","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rody","family":"Canning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerarda","family":"Cronin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly","family":"Dow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Dunn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adele","family":"Harrison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"James","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zarin","family":"Kalapesi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lajos","family":"Kovacs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orlando","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas D","family":"McMillan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakesh","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecil","family":"Ojah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abraham","family":"Peliowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalid","family":"Aziz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Piedboeuf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Riley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Faucher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Rouvinez-Bouali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koravangattu","family":"Sankaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Seshia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandesh","family":"Shivananda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zenon","family":"Cieslak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Synnes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herve","family":"Walti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2011,5,19]]},"reference":[{"key":"BFjp201168_CR1","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1067\/mob.2001.115280","volume":"185","author":"K Chan","year":"2001","unstructured":"Chan K, Ohlsson A, Synnes A, Lee DS, Chien LY, Lee SK . Survival, morbidity, and resource use of infants of 25 weeks\u2019 gestational age or less. Am J Obstet Gynecol 2001; 185: 220\u2013226.","journal-title":"Am J Obstet Gynecol"},{"key":"BFjp201168_CR2","doi-asserted-by":"publisher","first-page":"1070","DOI":"10.1542\/peds.106.5.1070","volume":"106","author":"SK Lee","year":"2000","unstructured":"Lee SK, McMillan DD, Ohlsson A, Pendray M, Synnes A, Whyte R et al. Variations in practice and outcomes in the Canadian NICU network: 1996\u20131997. Pediatrics 2000; 106: 1070\u20131079.","journal-title":"Pediatrics"},{"key":"BFjp201168_CR3","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1016\/S0146-0005(03)00055-7","volume":"27","author":"AA Fanaroff","year":"2003","unstructured":"Fanaroff AA, Hack M, Walsh MC . The NICHD neonatal research network: changes in practice and outcomes during the first 15 years. Semin Perinatol 2003; 27: 281\u2013287.","journal-title":"Semin Perinatol"},{"key":"BFjp201168_CR4","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1542\/peds.110.1.143","volume":"110","author":"JD Horbar","year":"2002","unstructured":"Horbar JD, Badger GJ, Carpenter JH, Fanaroff AA, Kilpatrick S, LaCorte M et al. Trends in mortality and morbidity for very low birth weight infants, 1991\u20131999. Pediatrics 2002; 110: 143\u2013151.","journal-title":"Pediatrics"},{"key":"BFjp201168_CR5","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1542\/peds.2009-2959","volume":"126","author":"BJ Stoll","year":"2010","unstructured":"Stoll BJ, Hansen NI, Bell EF, Shankaran S, Laptook AR, Walsh MC et al. neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network. Pediatrics 2010; 126: 443\u2013456.","journal-title":"Pediatrics"},{"key":"BFjp201168_CR6","doi-asserted-by":"publisher","first-page":"E35","DOI":"10.1542\/peds.108.2.e35","volume":"108","author":"MS Kramer","year":"2001","unstructured":"Kramer MS, Platt RW, Wen SW, Joseph KS, Allen A, Abrahamowicz M et al. A new and improved population-based Canadian reference for birth weight for gestational age. Pediatrics 2001; 108: E35.","journal-title":"Pediatrics"},{"key":"BFjp201168_CR7","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1542\/peds.91.3.617","volume":"91","author":"DK Richardson","year":"1993","unstructured":"Richardson DK, Gray JE, McCormick MC, Workman K, Goldmann DA . Score for Neonatal Acute Physiology: a physiologic severity index for neonatal intensive care. Pediatrics 1993; 91: 617\u2013623.","journal-title":"Pediatrics"},{"key":"BFjp201168_CR8","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1542\/peds.82.4.527","volume":"82","author":"AT Shennan","year":"1988","unstructured":"Shennan AT, Dunn MS, Ohlsson A, Lennox K, Hoskins EM . Abnormal pulmonary outcomes in premature infants: prediction from oxygen requirement in the neonatal period. Pediatrics 1988; 82: 527\u2013532.","journal-title":"Pediatrics"},{"key":"BFjp201168_CR9","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1016\/S0022-3476(78)80282-0","volume":"92","author":"LA Papile","year":"1978","unstructured":"Papile LA, Burstein J, Burstein R, Koffler H . Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm. J Pediatr 1978; 92: 529\u2013534.","journal-title":"J Pediatr"},{"key":"BFjp201168_CR10","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1001\/archopht.123.7.991","volume":"123","author":"International Committee for the Classification of Retinopathy of Prematurity","year":"2005","unstructured":"International Committee for the Classification of Retinopathy of Prematurity. The International Classification of Retinopathy of Prematurity revisited. Arch Ophthalmol 2005; 123: 991\u2013999.","journal-title":"Arch Ophthalmol"},{"key":"BFjp201168_CR11","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/S0031-3955(16)34975-6","volume":"33","author":"MC Walsh","year":"1986","unstructured":"Walsh MC, Kliegman RM . Necrotizing enterocolitis: treatment based on staging criteria. Pediatr Clin North Am 1986; 33: 179\u2013201.","journal-title":"Pediatr Clin North Am"},{"key":"BFjp201168_CR12","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1542\/peds.2004-1497","volume":"115","author":"GM Stoelhorst","year":"2005","unstructured":"Stoelhorst GM, Rijken M, Martens SE, Brand R, den Ouden AL, Wit JM et al. Changes in neonatology: comparison of two cohorts of very preterm infants (gestational age <32 weeks): the Project On Preterm and Small for Gestational Age Infants 1983 and the Leiden Follow-Up Project on Prematurity 1996\u20131997. Pediatrics 2005; 115: 396\u2013405.","journal-title":"Pediatrics"},{"key":"BFjp201168_CR13","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/1471-2431-6-2","volume":"6","author":"DA Paul","year":"2006","unstructured":"Paul DA, Leef KH, Locke RG, Bartoshesky L, Walrath J, Stefano JL . Increasing illness severity in very low birth weight infants over a 9-year period. BMC Pediatr 2006; 6: 2.","journal-title":"BMC Pediatr"},{"key":"BFjp201168_CR14","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1542\/peds.2009-1272","volume":"125","author":"NR Payne","year":"2010","unstructured":"Payne NR, Finkelstein MJ, Liu M, Kaempf JW, Sharek PJ, Olsen S . NICU practices and outcomes associated with 9 years of quality improvement collaboratives. Pediatrics 2010; 125: 437\u2013446.","journal-title":"Pediatrics"},{"key":"BFjp201168_CR15","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.jpeds.2009.07.013","volume":"156","author":"LW Doyle","year":"2010","unstructured":"Doyle LW, Roberts G, Anderson PJ . Outcomes at age 2 years of infants <28 weeks\u2019 gestational age born in Victoria in 2005. J Pediatr 2010; 156: 49\u201353.","journal-title":"J Pediatr"},{"key":"BFjp201168_CR16","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1542\/peds.2006-1472","volume":"119","author":"V Tommiska","year":"2007","unstructured":"Tommiska V, Heinonen K, Lehtonen L, Renlund M, Saarela T, Tammela O et al. No improvement in outcome of nationwide extremely low birth weight infant populations between 1996\u20131997 and 1999\u20132000. Pediatrics 2007; 119: 29\u201336.","journal-title":"Pediatrics"},{"key":"BFjp201168_CR17","doi-asserted-by":"publisher","first-page":"F188","DOI":"10.1136\/adc.2008.156745","volume":"95","author":"J Zeitlin","year":"2010","unstructured":"Zeitlin J, Ancel PY, Delmas D, Breart G, Papiernik E . Changes in care and outcome of very preterm babies in the Parisian region between 1998 and 2003. Arch Dis Child Fetal Neonatal Ed 2010; 95: F188\u2013F193.","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"BFjp201168_CR18","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1542\/peds.2008-0763","volume":"123","author":"K Itabashi","year":"2009","unstructured":"Itabashi K, Horiuchi T, Kusuda S, Kabe K, Itani Y, Nakamura T et al. Mortality rates for extremely low birth weight infants born in Japan in 2005. Pediatrics 2009; 123: 445\u2013450.","journal-title":"Pediatrics"},{"key":"BFjp201168_CR19","doi-asserted-by":"publisher","first-page":"e1328","DOI":"10.1542\/peds.2006-0359","volume":"118","author":"MC Walsh","year":"2006","unstructured":"Walsh MC, Yao Q, Horbar JD, Carpenter JH, Lee SK, Ohlsson A . Changes in the use of postnatal steroids for bronchopulmonary dysplasia in 3 large neonatal networks. Pediatrics 2006; 118: e1328\u2013e1335.","journal-title":"Pediatrics"},{"key":"BFjp201168_CR20","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1186\/1471-2288-3-28","volume":"3","author":"M Godwin","year":"2003","unstructured":"Godwin M, Ruhland L, Casson I, MacDonald S, Delva D, Birtwhistle R et al. Pragmatic controlled clinical trials in primary care: the struggle between external and internal validity. BMC Med Res Methodol 2003; 3: 28.","journal-title":"BMC Med Res Methodol"},{"key":"BFjp201168_CR21","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1002\/ppul.10032","volume":"33","author":"M Varughese","year":"2002","unstructured":"Varughese M, Patole S, Shama A, Whitehall J . Permissive hypercapnia in neonates: the case of the good, the bad, and the ugly. Pediatr Pulmonol 2002; 33: 56\u201364.","journal-title":"Pediatr Pulmonol"},{"key":"BFjp201168_CR22","doi-asserted-by":"publisher","first-page":"F241","DOI":"10.1136\/adc.2007.124263","volume":"94","author":"EM Dempsey","year":"2009","unstructured":"Dempsey EM, Al Hazzani F, Barrington KJ . Permissive hypotension in the extremely low birthweight infant with signs of good perfusion. Arch Dis Child Fetal Neonatal Ed 2009; 94: F241\u2013F244.","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"BFjp201168_CR23","doi-asserted-by":"publisher","first-page":"1959","DOI":"10.1056\/NEJMsa0806033","volume":"362","author":"WA Carlo","year":"2010","unstructured":"Carlo WA, Finer NN, Walsh MC, Rich W, Gantz MG, Laptook AR et al. Target ranges of oxygen saturation in extremely preterm infants. N Engl J Med 2010; 362: 1959\u20131969.","journal-title":"N Engl J Med"},{"key":"BFjp201168_CR24","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1056\/NEJMra0904308","volume":"362","author":"LJ Muglia","year":"2010","unstructured":"Muglia LJ, Katz M . The enigma of spontaneous preterm birth. N Engl J Med 2010; 362: 529\u2013535.","journal-title":"N Engl J Med"}],"container-title":["Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/jp201168.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/jp201168","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/jp201168.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T11:45:16Z","timestamp":1647603916000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/jp201168"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5,19]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["BFjp201168"],"URL":"https:\/\/doi.org\/10.1038\/jp.2011.68","relation":{},"ISSN":["0743-8346","1476-5543"],"issn-type":[{"value":"0743-8346","type":"print"},{"value":"1476-5543","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,5,19]]},"assertion":[{"value":"16 March 2011","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 April 2011","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 April 2011","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 May 2011","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}