{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:25:07Z","timestamp":1787761507626,"version":"build-2784847793"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2014,12,4]],"date-time":"2014-12-04T00:00:00Z","timestamp":1417651200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2014,12,4]],"date-time":"2014-12-04T00:00:00Z","timestamp":1417651200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Perinatol"],"published-print":{"date-parts":[[2015,5]]},"DOI":"10.1038\/jp.2014.217","type":"journal-article","created":{"date-parts":[[2014,12,4]],"date-time":"2014-12-04T13:57:20Z","timestamp":1417701440000},"page":"373-378","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Serial aEEG recordings in a cohort of extremely preterm infants: feasibility and safety"],"prefix":"10.1038","volume":"35","author":[{"given":"A S","family":"Davis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M G","family":"Gantz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6012-1168","authenticated-orcid":false,"given":"B","family":"Do","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Shankaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S E G","family":"Hamrick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K A","family":"Kennedy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J E","family":"Tyson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L F","family":"Chalak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A R","family":"Laptook","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R F","family":"Goldstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S R","family":"Hintz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R D","family":"Higgins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M B","family":"Ball","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E C","family":"Hale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K P","family":"Van Meurs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,12,4]]},"reference":[{"key":"BFjp2014217_CR1","first-page":"672","volume":"27","author":"D Maynard","year":"1969","unstructured":"Maynard D, Prior PF, Scott DF . A continuous monitoring device for cerebral activity. Electroencephalogr Clin Neurophysiol 1969; 27: 672\u2013673.","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"BFjp2014217_CR2","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1007\/s12028-009-9324-7","volume":"12","author":"HC Glass","year":"2010","unstructured":"Glass HC, Bonifacio SL, Peloquin S, Shimotake T, Sehring S, Sun Y et al. Neurocritical care for neonates. Neurocrit Care 2010; 12: 421\u2013429.","journal-title":"Neurocrit Care"},{"issue":"6","key":"BFjp2014217_CR3","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1016\/j.siny.2006.07.011","volume":"11","author":"L Hellstr\u00f6m-Westas","year":"2006","unstructured":"Hellstr\u00f6m-Westas L, Ros\u00e9n I . Continuous brain-function monitoring: state of the art in clinical practice. Semin Fetal Neonatal Med 2006; 11 (6): 503\u2013511.","journal-title":"Semin Fetal Neonatal Med"},{"key":"BFjp2014217_CR4","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.pediatrneurol.2011.11.006","volume":"46","author":"HC Glass","year":"2012","unstructured":"Glass HC, Kan J, Bonifacio SL, Ferriero DM . Neonatal seizures: treatment practices among term and preterm infants. Pediatr Neurol 2012; 46: 111\u2013115.","journal-title":"Pediatr Neurol"},{"key":"BFjp2014217_CR5","doi-asserted-by":"publisher","first-page":"F19","DOI":"10.1136\/fn.81.1.F19","volume":"81","author":"MC Toet","year":"1999","unstructured":"Toet MC, Hellstr\u00f6m-Westas L, Groenendaal F, Eken P, de Vries LS . Amplitude integrated EEG 3 and 6\u2009h after birth in full term neonates with hypoxic-ischemic encephalopathy. Arch Dis Child Fetal Neonatal Ed 1999; 81: F19\u2013F23.","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"BFjp2014217_CR6","doi-asserted-by":"publisher","first-page":"F245","DOI":"10.1136\/adc.2004.064964","volume":"90","author":"LGM van Rooij","year":"2005","unstructured":"van Rooij LGM, Toet MC, Osredkar D, van Huffelen AC, Groenendaal F, de Vries LS . Recovery of amplitude-integrated electroencephalographic background patterns within 24\u2009h of perinatal asphyxia. Arch Dis Child Fetal Neonatal Ed 2005; 90: F245\u2013F251.","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"BFjp2014217_CR7","doi-asserted-by":"publisher","first-page":"e131","DOI":"10.1542\/peds.2009-2938","volume":"126","author":"M Thoresen","year":"2010","unstructured":"Thoresen M, Hellstrom-Westas L, Liu X, de Vries LS . Effect of hypothermia on amplitude-integrated electrocephalography in infants with asphyxia. Pediatrics 2010; 126: e131\u2013e139.","journal-title":"Pediatrics"},{"key":"BFjp2014217_CR8","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1542\/peds.2004-0863","volume":"115","author":"D Osredkar","year":"2005","unstructured":"Osredkar D, Toet MC, van Rooij LGM, van Huffelen AC, Groenendaal F, de Vries LS . Sleep-wake cycling on amplitude-integrated electroencephalography in term newborns with hypoxic-ischemic encephalopathy. Pediatrics 2005; 115: 327\u2013332.","journal-title":"Pediatrics"},{"key":"BFjp2014217_CR9","doi-asserted-by":"crossref","unstructured":"Azzopardi D on behalf of the TOBY study group. Predictive value of amplitude integrated EEG in infants with hypoxic ischaemic encephalopathy: data from a randomised trial of therapeutic hypothermia. Arch Dis Child Fetal Neonat Ed 2013.","DOI":"10.1136\/archdischild-2013-303710"},{"issue":"1","key":"BFjp2014217_CR10","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1203\/PDR.0b013e31821ba200","volume":"70","author":"K Klebermass","year":"2011","unstructured":"Klebermass K, Olischar M, Waldhoer T, Fuiko R, Pollak A, Weninger M et al. Pattern predicts further outcome in preterm infants. Pediatr Res 2011; 70 (1): 102\u2013108.","journal-title":"Pediatr Res"},{"key":"BFjp2014217_CR11","doi-asserted-by":"publisher","first-page":"F108","DOI":"10.1136\/adc.2009.180539","volume":"96","author":"CR West","year":"2011","unstructured":"West CR, Harding JE, Williams CE, Nolan M, Battin MR . Cot-side electroencephalography for outcome prediction in preterm infants: observational study. Arch Dis Child Fetal Neonat Ed 2011; 96: F108\u2013F113.","journal-title":"Arch Dis Child Fetal Neonat Ed"},{"issue":"3","key":"BFjp2014217_CR12","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1111\/j.1442-200X.2010.03270.x","volume":"53","author":"M El-Dib","year":"2011","unstructured":"El-Dib M, Massaro AN, Glass P, Bulas D, Badrawi N, Orabi A et al. Early amplitude integrated EEG and outcome of very low birth weight infants. Pediatr Int 2011; 53 (3): 315\u2013312.","journal-title":"Pediatr Int"},{"key":"BFjp2014217_CR13","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1542\/peds.2009-2959","volume":"126","author":"BJ Stoll","year":"2010","unstructured":"Stoll BJ, Hansen NI, Bell EF, Shankaran S, Laptook AR, Walsh MC et al. Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network. Pediatrics 2010; 126: 443\u2013456.","journal-title":"Pediatrics"},{"issue":"147","key":"BFjp2014217_CR14","first-page":"e141","volume":"196","author":"AA Fanaroff","year":"2007","unstructured":"Fanaroff AA, Stoll BJ, Wright LL, Carlo WA, Ehrenkranz RA, Stark AR et al. Trends in morbidity and mortality for very low birthweight infants. Am J Obstet Gynecol 2007; 196 (147): e141\u2013e148.","journal-title":"Am J Obstet Gynecol"},{"key":"BFjp2014217_CR15","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1542\/peds.113.1.e61","volume":"113","author":"M Olischar","year":"2004","unstructured":"Olischar M, Klebermass K, Kuhle S, Hulek M, Kohlhauser C, Rucklinger E et al. Reference values for amplitude-integrated electroencephalographic activity in preterm infants younger than 30 weeks' gestational age. Pediatrics 2004; 113: 61\u201366.","journal-title":"Pediatrics"},{"key":"BFjp2014217_CR16","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1038\/sj.jp.7211291","volume":"25","author":"J Sisman","year":"2005","unstructured":"Sisman J, Campbell DE, Brion LP, Amplitude-integrated EEG . In preterm infants: maturation of background pattern and amplitude voltage with postmenstrual age and gestational age. J Perinatol 2005; 25: 391\u2013396.","journal-title":"J Perinatol"},{"key":"BFjp2014217_CR17","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1542\/peds.112.4.855","volume":"112","author":"VF Burdjalov","year":"2003","unstructured":"Burdjalov VF, Baumgart S, Spitzer AR . Cerebral function monitoring: a new scoring system for the evaluation of brain maturation in neonates. Pediatrics 2003; 112: 855\u2013861.","journal-title":"Pediatrics"},{"key":"BFjp2014217_CR18","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1016\/j.earlhumdev.2009.10.004","volume":"85","author":"V Soubasi","year":"2009","unstructured":"Soubasi V, Mitsakis K, Nakas CT, Petridou S, Sarafidis K, Griva M et al. The influence of extrauterine life on the aEEG maturation in normal preterm infants. Early Hum Dev 2009; 85: 761\u2013765.","journal-title":"Early Hum Dev"},{"issue":"2","key":"BFjp2014217_CR19","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1038\/pr.2012.171","volume":"73","author":"E Griesmaier","year":"2013","unstructured":"Griesmaier E, Enot DP, Bachmann M, Neubauer V, Hellstr\u00f6m-Westas L, Kiechl-Kohlendorfer U et al. Systematic characterization of amplitude-integrated EEG signals for monitoring the preterm brain. Pediatr Res 2013; 73 (2): 226\u2013235.","journal-title":"Pediatr Res"},{"key":"BFjp2014217_CR20","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1111\/j.1651-2227.1990.tb11324.x","volume":"79","author":"E Thornberg","year":"1990","unstructured":"Thornberg E, Thiringer K . Normal pattern of the cerebral function monitor trace in term and preterm neonates. Acta Paediatr Scand 1990; 79: 20\u201325.","journal-title":"Acta Paediatr Scand"},{"key":"BFjp2014217_CR21","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1159\/000252969","volume":"97","author":"HJ Niemarkt","year":"2010","unstructured":"Niemarkt HJ, Andriessen P, Peters CHL, Pasman JW, Blanco CE, Zimmermann LJ et al. Quantitative analysis of amplitude-integrated electroencephalogram patterns in stable preterm infants, with normal neurologic development at one year. Neonatology 2010; 97: 175\u2013182.","journal-title":"Neonatology"},{"key":"BFjp2014217_CR22","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.earlhumdev.2011.08.008","volume":"88","author":"HJ Niemarkt","year":"2012","unstructured":"Niemarkt HJ, Jennekens W, Maartens IA, Wassenberg T, van Aken M, Katgert T et al. Multi-channel amplitude-integrated EEG characteristics in preterm infants with a normal neurodevelopment at two years corrected age. Early Hum Dev 2012; 88: 209\u2013216.","journal-title":"Early Hum Dev"},{"issue":"5","key":"BFjp2014217_CR23","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1016\/j.pediatrneurol.2010.11.018","volume":"44","author":"LF Chalak","year":"2011","unstructured":"Chalak LF, Sikes NC, Mason MJ, Kaiser JR . Low-voltage aEEG as predictor of intracranial hemorrhage in preterm infants. Pediatr Neurol 2011; 44 (5): 364\u2013369.","journal-title":"Pediatr Neurol"},{"key":"BFjp2014217_CR24","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1203\/PDR.0b013e3181d4ecda","volume":"67","author":"JR Bowen","year":"2010","unstructured":"Bowen JR, Paradisis M, Shah D . Decreased aEEG continuity and baseline variability in the first 48\u2009h of life associated with poor short-term outcome in neonates born before 29 weeks gestation. Pediatr Res 2010; 67: 538\u2013544.","journal-title":"Pediatr Res"},{"issue":"5","key":"BFjp2014217_CR25","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/j.earlhumdev.2011.02.006","volume":"87","author":"HJ ter Horst","year":"2011","unstructured":"ter Horst HJ, Jongbloed-Pereboom M, van Eykern LA, Bos AF . Amplitude-integrated electroencephalographic activity is suppressed in preterm infants with high scores on illness severity. Early Hum Dev 2011; 87 (5): 385\u2013390.","journal-title":"Early Hum Dev"},{"key":"BFjp2014217_CR26","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1111\/j.1651-2227.2012.02677.x","volume":"101","author":"S Wikstr\u00f6m","year":"2012","unstructured":"Wikstr\u00f6m S, Pupp IH, Ros\u00e9n I, Norman E, Fellman V, Ley D et al. Early single-channel aEEG\/EEG predicts outcome in very preterm infants. Acta Paediatr 2012; 101: 719\u2013726.","journal-title":"Acta Paediatr"},{"key":"BFjp2014217_CR27","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1542\/peds.111.1.27","volume":"111","author":"TE Inder","year":"2003","unstructured":"Inder TE, Buckland L, Williams CD, Spencer C, Gunning MI, Darlow BA et al. Lowered electroencephalographic spectral edge frequency predicts the presence of cerebral white matter injury in premature infants. Pediatrics 2003; 111: 27\u201333.","journal-title":"Pediatrics"},{"issue":"1","key":"BFjp2014217_CR28","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1203\/PDR.0b013e3181bf5914","volume":"67","author":"DK Shah","year":"2010","unstructured":"Shah DK, Zempel J, Barton T, Lukas K, Inder TE . Electrographic seizures in preterm infants during the first week of life are associated with cerebral injury. Pediatr Res 2010; 67 (1): 102\u2013106.","journal-title":"Pediatr Res"},{"key":"BFjp2014217_CR29","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/j.earlhumdev.2010.06.006","volume":"86","author":"JB Helderman","year":"2010","unstructured":"Helderman JB, Welch CD, Leng X, O'Shea TM . Sepsis-associated electroencephalographic changes in extremely low gestational age neonates. Early Hum Dev 2010; 86: 509\u2013513.","journal-title":"Early Hum Dev"},{"key":"BFjp2014217_CR30","doi-asserted-by":"publisher","first-page":"1743","DOI":"10.1111\/j.1651-2227.2007.00462.x","volume":"96","author":"M Olischar","year":"2007","unstructured":"Olischar M, Klebermass K, Waldhoer T, Pollak A, Weninger M . Background patterns and sleep-wake cycles on amplitude-integrated electroencephalography in preterms younger than 30 weeks gestational age with peri-\/intraventricular hemorrhage. Acta Paediatr 2007; 96: 1743\u20131750.","journal-title":"Acta Paediatr"},{"key":"BFjp2014217_CR31","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1055\/s-2008-1071411","volume":"22","author":"L Hellstr\u00f6m-Westas","year":"1991","unstructured":"Hellstr\u00f6m-Westas L, Ros\u00e9n I, Svenningsen N . Cerebral function monitoring during the first week of life in extremely small low birthweight (ESLBW) infants. Neuropediatrics 1991; 22: 27\u201332.","journal-title":"Neuropediatrics"},{"key":"BFjp2014217_CR32","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1055\/s-2001-20408","volume":"32","author":"L Hellstr\u00f6m-Westas","year":"2001","unstructured":"Hellstr\u00f6m-Westas L, Klette H, Thorngren-Jerneck K, Ros\u00e9n I . Early prediction of outcome with aEEG in preterm infants with large intraventricular hemorrhages. Neuropediatrics 2001; 32: 319\u2013324.","journal-title":"Neuropediatrics"},{"key":"BFjp2014217_CR33","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1177\/1099800411403468","volume":"13","author":"SW Foreman","year":"2011","unstructured":"Foreman SW, Thorngate L, Burr RL, Thomas KA . Electrode challenges in amplitude-integrated electroencephalography (aEEG): research application of a novel noninvasive measure of brain function in preterm infants. Biol Res Nurs 2011; 13: 251\u2013259.","journal-title":"Biol Res Nurs"},{"key":"BFjp2014217_CR34","doi-asserted-by":"publisher","first-page":"1150","DOI":"10.1111\/j.1651-2227.2010.01809.x","volume":"99","author":"GB Boylan","year":"2010","unstructured":"Boylan GB, Burgoyne L, Moore C, O'Flaherty B, Rennie JM . An international survey of EEG use in the neonatal intensive care unit. Acta Paediatrica 2010; 99: 1150\u20131155.","journal-title":"Acta Paediatrica"},{"key":"BFjp2014217_CR35","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1007\/s11940-011-0144-7","volume":"13","author":"HC Glass","year":"2011","unstructured":"Glass HC, Bonifacio SL, Shimotake T, Ferriero DM . Neurocritical care for neonates. Curr Treat Options Neurol 2011; 13: 574\u2013589.","journal-title":"Curr Treat Options Neurol"}],"container-title":["Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/jp2014217.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/jp2014217","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/jp2014217.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T14:24:49Z","timestamp":1647613489000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/jp2014217"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,4]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["BFjp2014217"],"URL":"https:\/\/doi.org\/10.1038\/jp.2014.217","relation":{},"ISSN":["0743-8346","1476-5543"],"issn-type":[{"value":"0743-8346","type":"print"},{"value":"1476-5543","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12,4]]},"assertion":[{"value":"21 May 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 September 2014","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 September 2014","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 December 2014","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}