{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T19:27:49Z","timestamp":1761766069907},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2016,6,16]],"date-time":"2016-06-16T00:00:00Z","timestamp":1466035200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2016,6,16]],"date-time":"2016-06-16T00:00:00Z","timestamp":1466035200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Perinatol"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1038\/jp.2016.94","type":"journal-article","created":{"date-parts":[[2016,6,16]],"date-time":"2016-06-16T13:02:44Z","timestamp":1466082164000},"page":"870-873","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Continuous infusion versus intermittent flushing: maintaining peripheral intravenous access in newborn infants"],"prefix":"10.1038","volume":"36","author":[{"given":"D","family":"Stok","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J W","family":"Wieringa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,6,16]]},"reference":[{"key":"BFjp201694_CR1","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1097\/NAN.0b013e31818c0d4a","volume":"6","author":"A Flint","year":"2008","unstructured":"Flint A, Davies M . The intravenous cannula for newborn infants requiring only intravenous medication. J Infus Nurs 2008; 6: 346\u2013349.","journal-title":"J Infus Nurs"},{"key":"BFjp201694_CR2","first-page":"146","volume":"23","author":"A Kalyn","year":"2000","unstructured":"Kalyn A, Blatz S, Pinelli JA . Comparison of continuous infusion and intermittent flushing methods in peripheral intravenous catheters in neonates. J Intraven Nurs 2000; 23: 146\u2013153.","journal-title":"J Intraven Nurs"},{"key":"BFjp201694_CR3","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1177\/000992288902800509","volume":"29","author":"J Taylor","year":"1989","unstructured":"Taylor J, Shannon R, Kilbride HW . Heparin lock intravenous line: use in newborn infants. Clin Pediatr 1989; 29: 237\u2013240.","journal-title":"Clin Pediatr"},{"key":"BFjp201694_CR4","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1515\/jpm-2011-1000","volume":"40","author":"A Perez","year":"2012","unstructured":"Perez A, Feuz I, Brotschi B, Bernet V . Intermittent flushing improves cannula patency compared to continuous infusion for peripherally inserted venous catheters in newborns: results from a prospective observational study. J Perinat Med 2012; 40: 311\u2013314.","journal-title":"J Perinat Med"},{"issue":"4","key":"BFjp201694_CR5","first-page":"CD004593","volume":"19","author":"A Flint","year":"2005","unstructured":"Flint A, McIntosh D, Davies MW . Continuous infusion versus intermittent flushing to prevent loss of function of peripheral intravenous catheters used for drug administration in newborn infants. Cochrane Database Syst Rev 2005; 19 (4): CD004593.","journal-title":"Cochrane Database Syst Rev"},{"key":"BFjp201694_CR6","first-page":"230","volume":"3","author":"J Pettit","year":"2003","unstructured":"Pettit J . Assessment of the infant with a peripheral intravenous device. Adv Neonatal Care 2003; 3: 230\u2013240.","journal-title":"Adv Neonatal Care"},{"key":"BFjp201694_CR7","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.1177\/106002809202601002","volume":"10","author":"J Nieto-Rodriguez","year":"1992","unstructured":"Nieto-Rodriguez J, Garcia-Martin MA, Berrada Hernandez MD, Hervas MH, Cano-Real O . Heparin and infusion phlebitis: a prospective study. Ann Pharmacother 1992; 10: 1211\u20131214.","journal-title":"Ann Pharmacother"},{"key":"BFjp201694_CR8","doi-asserted-by":"publisher","first-page":"845","DOI":"10.7326\/0003-4819-114-10-845","volume":"114","author":"D Maki","year":"1991","unstructured":"Maki D, Ringer M . Risk factors for infusion-related phlebitis with small peripheral venous catheters: a randomized controlled trial. Ann Intern Med 1991; 114: 845\u2013854.","journal-title":"Ann Intern Med"},{"key":"BFjp201694_CR9","first-page":"CD002774","volume":"19","author":"PS Shah","year":"2005","unstructured":"Shah PS, Ng E, Sinha AK . Heparine for prolonging peripheral intravenous catheter use in neonates. Cochrane Database Syst Rev 2005; 19: CD002774.","journal-title":"Cochrane Database Syst Rev"},{"key":"BFjp201694_CR10","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1038\/jp.2014.203","volume":"35","author":"A Upadhyay","year":"2015","unstructured":"Upadhyay A, Verma KK, Lal P, Chawla D, Sreenivas V . Heparin for prolonging peripheral intravenous catheter use in neonates: a randomized controlled trial. J Perinatol 2015; 35: 274\u2013277.","journal-title":"J Perinatol"},{"key":"BFjp201694_CR11","doi-asserted-by":"publisher","first-page":"2677","DOI":"10.1111\/j.1365-2648.2011.05718.x","volume":"67","author":"IJ Arnts","year":"2011","unstructured":"Arnts IJ, Heijnen JA, Wilbers HT, van der Wilt GJ, Groenewoud JM, Liem KD . Effectiveness of heparin solution versus normal saline in maintaining patency of intravenous locks in neonates: a double blind randomized controlled study. J Adv Nurs 2011; 67: 2677\u20132685.","journal-title":"J Adv Nurs"},{"key":"BFjp201694_CR12","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1097\/NAN.0b013e3182306491","volume":"34","author":"AK de Lima Jacinto","year":"2011","unstructured":"de Lima Jacinto AK, Avelar AFM, Pedreira MLG . Predisposing factors for infiltration in children submitted to peripheral venous catheterization. J Infus Nur 2011; 34: 391\u2013398.","journal-title":"J Infus Nur"}],"container-title":["Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/jp201694.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/jp201694","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/jp201694.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T22:36:16Z","timestamp":1692398176000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/jp201694"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,16]]},"references-count":12,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["BFjp201694"],"URL":"https:\/\/doi.org\/10.1038\/jp.2016.94","relation":{},"ISSN":["0743-8346","1476-5543"],"issn-type":[{"value":"0743-8346","type":"print"},{"value":"1476-5543","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,16]]},"assertion":[{"value":"7 January 2016","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 April 2016","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 May 2016","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 June 2016","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}