{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T02:10:09Z","timestamp":1744078209445,"version":"3.40.3"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2017,4,27]],"date-time":"2017-04-27T00:00:00Z","timestamp":1493251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2017,4,27]],"date-time":"2017-04-27T00:00:00Z","timestamp":1493251200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Perinatol"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1038\/jp.2017.56","type":"journal-article","created":{"date-parts":[[2017,4,27]],"date-time":"2017-04-27T13:00:43Z","timestamp":1493298043000},"page":"906-910","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Changes in thyroid hormone concentrations during neonatal extracorporeal membrane oxygenation"],"prefix":"10.1038","volume":"37","author":[{"given":"L","family":"Leeuwen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A F J","family":"van Heijst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"van Rosmalen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y B","family":"de Rijke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L W J E","family":"Beurskens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Tibboel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E L T","family":"van den Akker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"IJsselstijn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,4,27]]},"reference":[{"key":"BFjp201756_CR1","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1056\/NEJM199102213240805","volume":"324","author":"JG Thorpe-Beeston","year":"1991","unstructured":"Thorpe-Beeston JG, Nicolaides KH, Felton CV, Butler J, McGregor AM . Maturation of the secretion of thyroid hormone and thyroid-stimulating hormone in the fetus. N Eng J Med 1991; 324: 532\u2013536.","journal-title":"N Eng J Med"},{"key":"BFjp201756_CR2","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.1016\/0003-4975(94)90459-6","volume":"58","author":"RD Mainwaring","year":"1994","unstructured":"Mainwaring RD, Lamberti JJ, Billman GF, Nelson JC . Suppression of the pituitary thyroid axis after cardiopulmonary bypass in the neonate. Ann thorac Surg 1994; 58: 1078\u20131082.","journal-title":"Ann thorac Surg"},{"key":"BFjp201756_CR3","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1253\/circj.CJ-12-0834","volume":"77","author":"M Cantinotti","year":"2013","unstructured":"Cantinotti M, Lorenzoni V, Storti S, Moschetti R, Murzi B, Marotta M et al. Thyroid and brain natriuretic peptide response in children undergoing cardiac surgery for congenital heart disease- age-related variations and prognostic value. Circ J 2013; 77: 188\u2013197.","journal-title":"Circ J"},{"key":"BFjp201756_CR4","doi-asserted-by":"publisher","first-page":"1688","DOI":"10.1056\/NEJM199512213332507","volume":"333","author":"MI Surks","year":"1995","unstructured":"Surks MI, Sievert R . Drugs and thyroid function. N Eng J Med 1995; 333: 1688\u20131694.","journal-title":"N Eng J Med"},{"key":"BFjp201756_CR5","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1210\/er.2011-0007","volume":"32","author":"A Boelen","year":"2011","unstructured":"Boelen A, Kwakkel J, Fliers E . Beyond low plasma T3: local thyroid hormone metabolism during inflammation and infection. Endocr Rev 2011; 32: 670\u2013693.","journal-title":"Endocr Rev"},{"key":"BFjp201756_CR6","doi-asserted-by":"publisher","first-page":"1456","DOI":"10.1089\/thy.2014.0201","volume":"24","author":"G Van den Berghe","year":"2014","unstructured":"Van den Berghe G . Non-thyroidal illness in the ICU: a syndrome with different faces. Thyroid 2014; 24: 1456\u20131465.","journal-title":"Thyroid"},{"key":"BFjp201756_CR7","doi-asserted-by":"publisher","first-page":"816","DOI":"10.1016\/S2213-8587(15)00225-9","volume":"3","author":"E Fliers","year":"2015","unstructured":"Fliers E, Bianco AC, Langouche L, Boelen A . Thyroid function in critically ill patients. Lancet Diabetes Endocrinol 2015; 3: 816\u2013825.","journal-title":"Lancet Diabetes Endocrinol"},{"key":"BFjp201756_CR8","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1001\/jama.1981.03310260021020","volume":"245","author":"MF Slag","year":"1981","unstructured":"Slag MF, Morley JE, Elson MK, Crowson TW, Nuttall FQ, Shafer RB . Hypothyroxinemia in critically ill patients as a predictor of high mortality. JAMA 1981; 245: 43\u201345.","journal-title":"JAMA"},{"key":"BFjp201756_CR9","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1097\/00003246-199501000-00015","volume":"23","author":"PM Rothwell","year":"1995","unstructured":"Rothwell PM, Lawler PG . Prediction of outcome in intensive care patients using endocrine parameters. Crit Care Med 1995; 23: 78\u201383.","journal-title":"Crit Care Med"},{"key":"BFjp201756_CR10","doi-asserted-by":"publisher","first-page":"5613","DOI":"10.1210\/jc.2005-0888","volume":"90","author":"M den Brinker","year":"2005","unstructured":"den Brinker M, Joosten KF, Visser TJ, Hop WC, de Rijke YB, Hazelzet JA et al. Euthyroid sick syndrome in meningococcal sepsis: the impact of peripheral thyroid hormone metabolism and binding proteins. J Clin Endocrinol Metab 2005; 90: 5613\u20135620.","journal-title":"J Clin Endocrinol Metab"},{"key":"BFjp201756_CR11","doi-asserted-by":"publisher","first-page":"1448","DOI":"10.1378\/chest.08-1816","volume":"135","author":"G Bello","year":"2009","unstructured":"Bello G, Pennisi MA, Montini L, Silva S, Maviglia R, Cavallaro F et al. Nonthyroidal illness syndrome and prolonged mechanical ventilation in patients admitted to the ICU. Chest 2009; 135: 1448\u20131454.","journal-title":"Chest"},{"key":"BFjp201756_CR12","doi-asserted-by":"publisher","first-page":"e92","DOI":"10.1007\/BF03347098","volume":"34","author":"A Kurt","year":"2011","unstructured":"Kurt A, Aygun AD, Sengul I, Sen Y, Citak Kurt AN, Ustundag B . Serum thyroid hormones levels are significantly decreased in septic neonates with poor outcome. J Endocrinol Invest 2011; 34: e92\u2013e96.","journal-title":"J Endocrinol Invest"},{"key":"BFjp201756_CR13","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1515\/jpm.2010.120","volume":"39","author":"GS Goldsmit","year":"2011","unstructured":"Goldsmit GS, Valdes M, Herzovich V, Rodriguez S, Chaler E, Golombek SG et al. Evaluation and clinical application of changes in thyroid hormone and TSH levels in critically ill full-term newborns. J Perinat Med 2011; 39: 59\u201364.","journal-title":"J Perinat Med"},{"key":"BFjp201756_CR14","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1542\/peds.2004-0192","volume":"115","author":"DJ Lim","year":"2005","unstructured":"Lim DJ, Herring MK, Leef KH, Getchell J, Bartoshesky LE, Paul DA . Hypothyroxinemia in mechanically ventilated term infants is associated with increased use of rescue therapies. Pediatrics 2005; 115: 406\u2013410.","journal-title":"Pediatrics"},{"key":"BFjp201756_CR15","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1159\/000448238","volume":"111","author":"L Leeuwen","year":"2016","unstructured":"Leeuwen L, van Heijst AF, Vijfhuize S, Beurskens LW, Weijman G, Tibboel D et al. Nationwide evaluation of congenital hypothyroidism screening during neonatal extracorporeal membrane oxygenation. Neonatology 2016; 111: 93\u201399.","journal-title":"Neonatology"},{"key":"BFjp201756_CR16","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1177\/026765910101600606","volume":"16","author":"DL Stewart","year":"2001","unstructured":"Stewart DL, Ssemakula N, MacMillan DR, Goldsmith LJ, Cook LN . Thyroid function in neonates with severe respiratory failure on extracorporeal membrane oxygenation. Perfusion 2001; 16: 469\u2013475.","journal-title":"Perfusion"},{"key":"BFjp201756_CR17","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1053\/j.semperi.2013.11.002","volume":"38","author":"ML Paden","year":"2014","unstructured":"Paden ML, Rycus PT, Thiagarajan RR, Registry E . Update and outcomes in extracorporeal life support. Semin Perinatol 2014; 38: 65\u201370.","journal-title":"Semin Perinatol"},{"key":"BFjp201756_CR18","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1016\/0022-3468(91)90708-2","volume":"26","author":"CJ Stolar","year":"1991","unstructured":"Stolar CJ, Snedecor SM, Bartlett RH . Extracorporeal membrane oxygenation and neonatal respiratory failure: experience from the extracorporeal life support organization. J Pediatr Surg 1991; 26: 563\u2013571.","journal-title":"J Pediatr Surg"},{"key":"BFjp201756_CR19","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1159\/000320622","volume":"98","author":"I Reiss","year":"2010","unstructured":"Reiss I, Schaible T, van den Hout L, Capolupo I, Allegaert K, van Heijst A et al. Standardized postnatal management of infants with congenital diaphragmatic hernia in Europe: the CDH EURO Consortium consensus. Neonatology 2010; 98: 354\u2013364.","journal-title":"Neonatology"},{"key":"BFjp201756_CR20","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1097\/00003246-199605000-00004","volume":"24","author":"MM Pollack","year":"1996","unstructured":"Pollack MM, Patel KM, Ruttimann UE . PRISM III: an updated Pediatric Risk of Mortality score. Crit Care Med 1996; 24: 743\u2013752.","journal-title":"Crit Care Med"},{"key":"BFjp201756_CR21","doi-asserted-by":"publisher","first-page":"1761","DOI":"10.1097\/CCM.0b013e31828a2bbd","volume":"41","author":"S Leteurtre","year":"2013","unstructured":"Leteurtre S, Duhamel A, Salleron J, Grandbastien B, Lacroix J, Leclerc F et al. PELOD-2: an update of the PEdiatric logistic organ dysfunction score. Crit Care Med 2013; 41: 1761\u20131773.","journal-title":"Crit Care Med"},{"key":"BFjp201756_CR22","doi-asserted-by":"publisher","first-page":"1747","DOI":"10.1097\/00003246-199422110-00008","volume":"22","author":"G Van den Berghe","year":"1994","unstructured":"Van den Berghe G, de Zegher F, Lauwers P . Dopamine suppresses pituitary function in infants and children. Crit Care Med 1994; 22: 1747\u20131753.","journal-title":"Crit Care Med"},{"key":"BFjp201756_CR23","volume-title":"Bayley scales of infant development - Second Edition - Nederlandse versie (BSID-II-NL)","author":"BF van der Meulen","year":"2002","unstructured":"van der Meulen BF, van der Ruiter SAJ, Lutje Spelberg HC, Smrkovsky M . Bayley scales of infant development - Second Edition - Nederlandse versie (BSID-II-NL). Harcourt Test Publishers: Amsterdam, 2002."},{"key":"BFjp201756_CR24","doi-asserted-by":"publisher","first-page":"3170","DOI":"10.1210\/jc.2012-1759","volume":"97","author":"AJ Lem","year":"2012","unstructured":"Lem AJ, de Rijke YB, van Toor H, de Ridder MA, Visser TJ, Hokken-Koelega AC . Serum thyroid hormone levels in healthy children from birth to adulthood and in short children born small for gestational age. J Clin Endocrinol Metab 2012; 97: 3170\u20133178.","journal-title":"J Clin Endocrinol Metab"},{"key":"BFjp201756_CR25","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1097\/01.MAT.0000105325.09779.FB","volume":"50","author":"MS Agus","year":"2004","unstructured":"Agus MS, Jaksic T . Critically low hormone and catecholamine concentrations in the primed extracorporeal life support circuit. ASAIO J 2004; 50: 65\u201367.","journal-title":"ASAIO J"},{"key":"BFjp201756_CR26","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1016\/S0022-3476(96)80133-8","volume":"128","author":"JD Fortenberry","year":"1996","unstructured":"Fortenberry JD, Bhardwaj V, Niemer P, Cornish JD, Wright JA, Bland L . Neutrophil and cytokine activation with neonatal extracorporeal membrane oxygenation. J Pediatr 1996; 128: 670\u2013678.","journal-title":"J Pediatr"},{"key":"BFjp201756_CR27","doi-asserted-by":"publisher","first-page":"S2347","DOI":"10.1016\/j.athoracsur.2006.02.073","volume":"81","author":"DJ Kozik","year":"2006","unstructured":"Kozik DJ, Tweddell JS . Characterizing the inflammatory response to cardiopulmonary bypass in children. Ann Thorac Surg 2006; 81: S2347\u2013S2354.","journal-title":"Ann Thorac Surg"},{"key":"BFjp201756_CR28","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1016\/S0022-5223(96)70053-3","volume":"112","author":"MC Seghaye","year":"1996","unstructured":"Seghaye MC, Grabitz RG, Duchateau J, Busse S, Dabritz S, Koch D et al. Inflammatory reaction and capillary leak syndrome related to cardiopulmonary bypass in neonates undergoing cardiac operations. J Thorac Cardiovasc Surg 1996; 112: 687\u2013697.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"BFjp201756_CR29","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1186\/s13054-015-1054-y","volume":"19","author":"S Leteurtre","year":"2015","unstructured":"Leteurtre S, Duhamel A, Deken V, Lacroix J, Leclerc F, Groupe Francophone de Reanimation et Urgences P. Daily estimation of the severity of organ dysfunctions in critically ill children by using the PELOD-2 score. Crit Care 2015; 19: 324.","journal-title":"Crit Care"},{"key":"BFjp201756_CR30","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1016\/0003-4975(94)00879-C","volume":"59","author":"B Murzi","year":"1995","unstructured":"Murzi B, Iervasi G, Masini S, Moschetti R, Vanini V, Zucchelli G et al. Thyroid hormones homeostasis in pediatric patients during and after cardiopulmonarybypass. Ann Thorac Surg 1995; 59: 481\u2013485.","journal-title":"Ann Thorac Surg"},{"key":"BFjp201756_CR31","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1210\/jcem-62-4-717","volume":"62","author":"PS Hamblin","year":"1986","unstructured":"Hamblin PS, Dyer SA, Mohr VS, Le Grand BA, Lim CF, Tuxen DV et al. Relationship between thyrotropin and thyroxine changes during recovery from severe hypothyroxinemia of critical illness. J Clin Endocrinol Metab 1986; 62: 717\u2013722.","journal-title":"J Clin Endocrinol Metab"},{"key":"BFjp201756_CR32","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1210\/jc.2013-1891","volume":"99","author":"J Leger","year":"2014","unstructured":"Leger J, Olivieri A, Donaldson M, Torresani T, Krude H, van Vliet G et al. European Society for Paediatric Endocrinology consensus guidelines on screening, diagnosis, and management of congenital hypothyroidism. J Clin Endocrinol Metab 2014; 99: 363\u2013384.","journal-title":"J Clin Endocrinol Metab"},{"key":"BFjp201756_CR33","first-page":"CD005945","volume":"1","author":"DA Osborn","year":"2007","unstructured":"Osborn DA, Hunt RW . Postnatal thyroid hormones for preterm infants with transient hypothyroxinaemia. Cochrane Database Syst Rev 2007 1 CD005945.","journal-title":"Cochrane Database Syst Rev"},{"key":"BFjp201756_CR34","doi-asserted-by":"publisher","first-page":"4648","DOI":"10.1210\/jc.2015-3078","volume":"100","author":"JJ Hollanders","year":"2015","unstructured":"Hollanders JJ, Israels J, van der Pal SM, Verkerk PH, Rotteveel J, Finken MJ et al. No association between transient hypothyroxinaemia of prematurity and neurodevelopmental outcome in young adulthood. J Clin Endocrinol Metab 2015; 100: 4648\u20134653.","journal-title":"J Clin Endocrinol Metab"},{"key":"BFjp201756_CR35","doi-asserted-by":"publisher","first-page":"S224","DOI":"10.1161\/CIRCULATIONAHA.109.926394","volume":"122","author":"MA Portman","year":"2010","unstructured":"Portman MA, Slee A, Olson AK, Cohen G, Karl T, Tong E et al. Triiodothyronine Supplementation in Infants and Children Undergoing Cardiopulmonary Bypass (TRICC): a multicenter placebo-controlled randomized trial: age analysis. Circulation 2010; 122: S224\u2013S233.","journal-title":"Circulation"},{"key":"BFjp201756_CR36","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1159\/000381711","volume":"84","author":"J Mittnacht","year":"2015","unstructured":"Mittnacht J, Choukair D, Kneppo C, Brunner R, Parzer P, Gorenflo M et al. Long-term neurodevelopmental outcome of children treated with tri-iodothyronine after cardiac surgery: follow-up of a Double-Blind, Randomized, Placebo-Controlled Study. Horm Res Paediatr 2015; 84: 130\u2013136.","journal-title":"Horm Res Paediatr"}],"container-title":["Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/jp201756.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/jp201756","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/doifinder\/10.1038\/jp.2017.56","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/www.nature.com\/articles\/jp201756.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T01:49:21Z","timestamp":1744076961000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/jp201756"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,27]]},"references-count":36,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["BFjp201756"],"URL":"https:\/\/doi.org\/10.1038\/jp.2017.56","relation":{},"ISSN":["0743-8346","1476-5543"],"issn-type":[{"type":"print","value":"0743-8346"},{"type":"electronic","value":"1476-5543"}],"subject":[],"published":{"date-parts":[[2017,4,27]]},"assertion":[{"value":"6 December 2016","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 March 2017","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 March 2017","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 April 2017","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}