{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T09:52:48Z","timestamp":1777542768916,"version":"3.51.4"},"reference-count":24,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[1972,6,1]],"date-time":"1972-06-01T00:00:00Z","timestamp":76204800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":15894,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[1972,6]]},"DOI":"10.1038\/ki.1972.53","type":"journal-article","created":{"date-parts":[[2007,6,20]],"date-time":"2007-06-20T13:09:19Z","timestamp":1182344959000},"page":"406-412","source":"Crossref","is-referenced-by-count":39,"title":["Effect of renin immunization on mercuric chloride and glycerol-induced renal failure"],"prefix":"10.1016","volume":"1","author":[{"given":"Walter","family":"Flamenbaum","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.A.","family":"Kotchen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donald E.","family":"Oken","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1038\/ki.1972.53_bb0010","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1161\/01.CIR.31.5.686","article-title":"Plasma renin activity in acute tubular necrosis and other renal diseases associated with hypertension","volume":"31","author":"Tu","year":"1965","journal-title":"Circulation"},{"key":"10.1038\/ki.1972.53_bb0015","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1159\/000179720","article-title":"Plasma renin activity in acute renal insufficiency","volume":"6","author":"Kokot","year":"1969","journal-title":"Nephron"},{"key":"10.1038\/ki.1972.53_bb0020","first-page":"253","article-title":"Renin and acute renal failure: Studies in man","volume":"1","author":"Brown","year":"1970","journal-title":"Lancet"},{"key":"10.1038\/ki.1972.53_bb0025","series-title":"Pathogenesis and Clinical Findings with Acute Renal Failure","first-page":"23","article-title":"Alterations in the glomerular filtration rate in acute renal failure","author":"Ruiz-Guinazu","year":"1971"},{"key":"10.1038\/ki.1972.53_bb0030","first-page":"473","article-title":"Angiotensin blood levels in hypertensive and nonhypertensive diseases","volume":"30","author":"Massani","year":"1966","journal-title":"Clin.Sci"},{"key":"10.1038\/ki.1972.53_bb0035","first-page":"629","article-title":"Renal renin and renin release in acute renal failure in the rat","volume":"27","author":"Hayes","year":"1968","journal-title":"Fed.Proc"},{"key":"10.1038\/ki.1972.53_bb0040","doi-asserted-by":"crossref","first-page":"610","DOI":"10.3181\/00379727-131-33937","article-title":"The prevention of acute renal failure in the rat by long-term saline loading: A possible role of the reninangiotensin axis","volume":"131","author":"McDonald","year":"1969","journal-title":"Proc.Soc.Exp.Biol.Med"},{"key":"10.1038\/ki.1972.53_bb0045","first-page":"309","article-title":"Micropuncture studies of the pathophysiology of acute renal failure in the rat","volume":"13","author":"Henry","year":"1968","journal-title":"Lab.Invest"},{"key":"10.1038\/ki.1972.53_bb0050","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1159\/000179922","article-title":"Maintenance of renal function in salt-loaded rats despite severe tubular necrosis induced by HgCl2","volume":"8","author":"DiBona","year":"1971","journal-title":"Nephron"},{"key":"10.1038\/ki.1972.53_bb0055","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1161\/01.RES.20.4.391","article-title":"Improved assay method for renin concentration and activity in human plasma","volume":"20","author":"Skinner","year":"1967","journal-title":"Circ.Res"},{"key":"10.1038\/ki.1972.53_bb0060","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1210\/jcem-29-10-1349","article-title":"Application of a radioimmunoassay for angiotensin I to the physiologic measurements of plasma renin activity in normal human subjects","volume":"25","author":"Haber","year":"1969","journal-title":"J.Clin.Endoc.Metab"},{"key":"10.1038\/ki.1972.53_bb0065","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1161\/01.RES.19.4.739","article-title":"Extraction, purification and assay of human renin free of angiotensinase","volume":"19","author":"Haas","year":"1966","journal-title":"Circ.Res"},{"key":"10.1038\/ki.1972.53_bb0070","unstructured":"Snedecor, O. W., and Cochran, W. G.: Statistical Methods, 6th edition, Ames, Iowa, Iowa State University Press, 1967."},{"key":"10.1038\/ki.1972.53_bb0075","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1159\/000179588","article-title":"Glycerol induced hemoglobinuric acute renal failure in the rat: II.The experimental model, predisposing factors, and pathophysiologic factors","volume":"4","author":"Thiel","year":"1967","journal-title":"Nephron"},{"key":"10.1038\/ki.1972.53_bb0080","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1172\/JCI105387","article-title":"Glycerol-induced hemoglobinuric acute renal failure in the rat.I.Micropuncture study of the development of oliguria","volume":"45","author":"Oken","year":"1966","journal-title":"J.Clin.Invest"},{"key":"10.1038\/ki.1972.53_bb0085","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1159\/000179923","article-title":"Micropuncture study of renal tubular factors in low dose mercury poisoning","volume":"8","author":"Flamenbaum","year":"1971","journal-title":"Nephron"},{"key":"10.1038\/ki.1972.53_bb0090","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1097\/00005792-196811000-00001","article-title":"Acute oliguric renal failure in man: Evidence for preferential renal cortical ischemia","volume":"47","author":"Hollenberg","year":"1968","journal-title":"Medicine"},{"key":"10.1038\/ki.1972.53_bb0095","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1056\/NEJM197006112822401","article-title":"Acute renal failure due to nephrotoxins.Renal hemodynamic studies in man","volume":"282","author":"Hollenberg","year":"1970","journal-title":"New Engl.J.Med"},{"key":"10.1038\/ki.1972.53_bb0100","first-page":"22","article-title":"Renal hemodynamics in uranyl nitrate induced acute renal failure","volume":"5","author":"Flamenbaum","year":"1971","journal-title":"Abstracts of Am.Soc.Neph."},{"key":"10.1038\/ki.1972.53_bb0105","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1161\/01.RES.29.2.128","article-title":"Intrarenal hemodynamics in glycerol-induced myohemoglobinuric acute renal failure","volume":"29","author":"Ayer","year":"1971","journal-title":"Circ.Res"},{"key":"10.1038\/ki.1972.53_bb0110","first-page":"528","article-title":"The renin-angiotensin system in acute renal failure in the rat","volume":"25","author":"DiBona","year":"1971","journal-title":"Lab.Invest"},{"key":"10.1038\/ki.1972.53_bb0115","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1007\/BF00362491","article-title":"Die fr\u00fchdistale Natriumkonzentration in Rattennieren nach renaler Isch\u00e4mie und h\u00e4morrhagischer Hypotension: Ein Beitrag zur Pathogenese der postisch\u00e4mischen und posth\u00e4morrhagischen Filtraterniedrigung","volume":"287","author":"Schnermann","year":"1966","journal-title":"Pfl\u00fcgers Arch.ges.Physiol"},{"issue":"Suppl.II","key":"10.1038\/ki.1972.53_bb0120","first-page":"79","article-title":"Composition of tubular fluid in the macula densa segment as a factor regulating the function of the juxtaglomerular apparatus","volume":"20\/21","author":"Thurau","year":"1967","journal-title":"Circ.Res"},{"issue":"Suppl.II","key":"10.1038\/ki.1972.53_bb0125","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1161\/01.RES.28.5_Suppl_2.II-96","article-title":"Effects of angiotensin infusion on catecholamine uptake and reactivity in blood vessels","volume":"28\/29","author":"Khairallah","year":"1971","journal-title":"Circ.Res"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815310528?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815310528?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T01:11:48Z","timestamp":1634778708000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815310528"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1972,6]]},"references-count":24,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1972,6]]}},"alternative-id":["S0085253815310528"],"URL":"https:\/\/doi.org\/10.1038\/ki.1972.53","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[1972,6]]}}}