{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T21:09:01Z","timestamp":1790284141785,"version":"4.1.0"},"reference-count":70,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[1974,7,1]],"date-time":"1974-07-01T00:00:00Z","timestamp":141868800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":15134,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[1974,7]]},"DOI":"10.1038\/ki.1974.74","type":"journal-article","created":{"date-parts":[[2007,6,20]],"date-time":"2007-06-20T12:52:53Z","timestamp":1182343973000},"page":"24-37","source":"Crossref","is-referenced-by-count":89,"title":["Medullary plasma flow and intravascular leukocyte accumulation in acute renal failure"],"prefix":"10.1016","volume":"6","author":[{"given":"Kim","family":"Solez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth C.","family":"Kramer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer A.","family":"Fox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert H.","family":"Heptinstall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/ki.1974.74_bb0010","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1097\/00005792-196811000-00001","article-title":"Acute oliguric renal failure in man: Evidence for preferential renal cortical ischemia","volume":"47","author":"Hollenberg","year":"1968","journal-title":"Medicine"},{"key":"10.1038\/ki.1974.74_bb0015","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1056\/NEJM197006112822401","article-title":"Acute renal failure due to nephrotoxins: Renal hemodynamics and angiographic studies in man","volume":"282","author":"Hollenberg","year":"1970","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1974.74_bb0020","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1161\/01.RES.29.2.128","article-title":"Intrarenal hemodynamics in glycerol-induced myohemoglobinuric acute renal failure in the rat","volume":"29","author":"Ayer","year":"1971","journal-title":"Circ Res"},{"key":"10.1038\/ki.1974.74_bb0025","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1161\/01.RES.31.5.682","article-title":"Experimental acute renal failure induced by uranyl nitrate in the dog","volume":"31","author":"Flamenbaum","year":"1972","journal-title":"Circ Res"},{"key":"10.1038\/ki.1974.74_bb0030","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/ki.1973.26","article-title":"Xenon transit through the oliguric human kidney: Analysis by maximum likelihood","volume":"3","author":"Hollenberg","year":"1973","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1974.74_bb0035","first-page":"31a","article-title":"The pathology of acute renal failure (ARF): Leukocyte accumulation in the vasa recta","volume":"74","author":"Solez","year":"1974","journal-title":"Am J Pathol"},{"key":"10.1038\/ki.1974.74_bb0040","first-page":"429","article-title":"Structural renal damage and its relation to clinical features in acute oliguric renal failure","volume":"31","author":"Finckh","year":"1962","journal-title":"Q J Med"},{"key":"10.1038\/ki.1974.74_bb0045","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1002\/path.1700750221","article-title":"Intravascular haemopoiesis in the renal medulla in shock","volume":"75","author":"Baker","year":"1958","journal-title":"J Pathol Bacteriol"},{"key":"10.1038\/ki.1974.74_bb0050","first-page":"1336","article-title":"Das Vorkommen unreifer Blutzellen im Leukozytenkonzentrat nach Kreislaufkollaps","volume":"94","author":"Remmele","year":"1964","journal-title":"Schweiz Med Wochenschr"},{"key":"10.1038\/ki.1974.74_bb0055","first-page":"170","article-title":"Herkunft und Bedeutung der intravaselen Zellansammlungen in der sog. Schockniere","volume":"68","author":"Remmele","year":"1964","journal-title":"Verh Dtsch Ges Pathol"},{"key":"10.1038\/ki.1974.74_bb0060","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1007\/BF02073996","article-title":"Untersuchung \u00fcber die Cytologie des Blutes im Kreislaufshock: I. Die Cytologie des Zellkonzentrates bei Schockpatienten und bei Kaninchen mit Entblutungsschock","volume":"147","author":"Remmele","year":"1968","journal-title":"Z Ges Exp Med"},{"key":"10.1038\/ki.1974.74_bb0065","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1007\/BF01745646","article-title":"Zur pathologischen Anatomie des Kreislaufshocks beim Menschen: III. Ansammlungen von Blut- und Knochenmarkszellen in den Markgefassen der Niere","volume":"46","author":"Remmele","year":"1968","journal-title":"Klin Wochenschr"},{"key":"10.1038\/ki.1974.74_bb0070","series-title":"Kidney Hormones","first-page":"31","article-title":"Distribution of blood flow in the kidney","author":"Ladefoged","year":"1971"},{"key":"10.1038\/ki.1974.74_bb0075","series-title":"The renal circulation, in The Kidney","first-page":"1","volume":"III","author":"THURAU","year":"1971"},{"key":"10.1038\/ki.1974.74_bb0080","series-title":"Intrarenal distribution of blood flow, in Advances in Nephrology","first-page":"125","volume":"I","author":"Grunfeld JP","year":"1971"},{"key":"10.1038\/ki.1974.74_bb0085","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1161\/01.RES.9.3.614","article-title":"Blood flow in the renal medulla","volume":"9","author":"Lilienfield","year":"1961","journal-title":"Circ Res"},{"key":"10.1038\/ki.1974.74_bb0090","first-page":"394","article-title":"Renal medullary plasma flow in hypertension","volume":"31","author":"Ganguli","year":"1972","journal-title":"Fed Proc"},{"key":"10.1038\/ki.1974.74_bb0095","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1152\/jappl.1972.32.4.533","article-title":"Geometric error in tissue gamma counting","volume":"32","author":"Katz","year":"1972","journal-title":"J Appl Physiol"},{"key":"10.1038\/ki.1974.74_bb0100","first-page":"243","article-title":"Polyuria, hypertension, and altered renal function in experimental microembolic renal disease: Relation to hypertensive diseases in man","volume":"27","author":"Solez","year":"1972","journal-title":"Lab Invest"},{"key":"10.1038\/ki.1974.74_bb0105","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1177\/10.6.741","article-title":"Histochemical methods for acid phosphatase using hexazonium pararosanilin as a coupler","volume":"10","author":"Barka","year":"1962","journal-title":"J Histochem Cytochem"},{"key":"10.1038\/ki.1974.74_bb0110","first-page":"213","article-title":"Experimental papillary necrosis of the kidney: II. Electron microscopic and histochemical studies","volume":"68","author":"Hill","year":"1972","journal-title":"Am J Pathol"},{"key":"10.1038\/ki.1974.74_bb0115","series-title":"Introduction to Statistical Analysis","author":"Dixon","year":"1969"},{"key":"10.1038\/ki.1974.74_bb0120","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/BF00583423","article-title":"Haemodynamik des Nierenmarks: I. Capillarie Passagezet, Durchblutung, Gewebshaematokrit, und O2-Verbrauch des Nierenmarks in situ","volume":"270","author":"Kramer","year":"1960","journal-title":"Arch Ges Physiol"},{"key":"10.1038\/ki.1974.74_bb0125","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/0002-9343(64)90181-0","article-title":"Renal hemodynamics","volume":"36","author":"Thurau","year":"1964","journal-title":"Am J Med"},{"key":"10.1038\/ki.1974.74_bb0130","first-page":"1011","article-title":"The renal tubule (nephron) as affected by mercury","volume":"18","author":"Edwards","year":"1942","journal-title":"Am J Pathol"},{"key":"10.1038\/ki.1974.74_bb0135","first-page":"297","article-title":"Mercury nephrotoxicity in the rat","volume":"41","author":"Rodin","year":"1962","journal-title":"Am J Pathol"},{"key":"10.1038\/ki.1974.74_bb0140","first-page":"218","article-title":"Renal response of the rat to mercury: The effect of sex and sex hormones","volume":"79","author":"Harber","year":"1965","journal-title":"Arch Pathol"},{"key":"10.1038\/ki.1974.74_bb0145","first-page":"1","article-title":"Histochemical studies of nephrotoxicity with sublethal doses of mercury in rats","volume":"46","author":"Taylor","year":"1965","journal-title":"Am J Pathol"},{"key":"10.1038\/ki.1974.74_bb0150","first-page":"405","article-title":"Repair of the nephron following injury with mercuric chloride","volume":"51","author":"Cuppage","year":"1967","journal-title":"Am J Pathol"},{"key":"10.1038\/ki.1974.74_bb0155","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/S0022-5320(67)80079-0","article-title":"The fine structure of the blood vessels of the renal medulla with particular reference to the control of the medullary circulation","volume":"19","author":"Moffat","year":"1967","journal-title":"J Ultrastruct Res"},{"key":"10.1038\/ki.1974.74_bb0160","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1016\/S0140-6736(66)91007-5","article-title":"Counter-current exchange between the vasa recta and the loop of Henle","volume":"1","author":"Lever","year":"1966","journal-title":"Lancet"},{"key":"10.1038\/ki.1974.74_bb0165","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/BF00332797","article-title":"Electron microscopic observations on the juxtamedullary efferent arterioles and arteriolae rectae in kidneys of rats","volume":"97","author":"Newstead","year":"1968","journal-title":"Z Zellforsch Mikrosk Anat"},{"key":"10.1038\/ki.1974.74_bb0170","first-page":"227","article-title":"Effect of hyperosmotic albumin and hypertonic saline infusion on renal medullary blood flow","volume":"36","author":"Harsing","year":"1969","journal-title":"Acta Physiol Acad Sci Hung"},{"key":"10.1038\/ki.1974.74_bb0175","first-page":"1","article-title":"Alterations in intrarenal blood flow distribution: Methods of measurement and relationship to sodium balance","volume":"21","author":"Stein","year":"1973","journal-title":"Circ Res"},{"key":"10.1038\/ki.1974.74_bb0180","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1172\/JCI107172","article-title":"Mechanism of redistribution of renal cortical blood flow during hemorrhagic hypotension in the dog","volume":"52","author":"Stein","year":"1973","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1974.74_bb0185","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1152\/ajplegacy.1971.221.5.1297","article-title":"Effect of saline diuresis on intrarenal blood flow in the rat","volume":"221","author":"Wallin","year":"1971","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1974.74_bb0190","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1161\/01.RES.19.1.167","article-title":"Intrarenal distribution of blood flow in dogs during hemorrhagic hypotension","volume":"19","author":"Carriere","year":"1966","journal-title":"Circ Res"},{"key":"10.1038\/ki.1974.74_bb0195","series-title":"Schock, Pathogenese und Therapie","article-title":"Das akute Nierenversagen im Schock","author":"Kramer","year":"1962"},{"key":"10.1038\/ki.1974.74_bb0200","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1172\/JCI105745","article-title":"Effect of hemorrhage and retransfusion on intrarenal distribution of blood flow in dogs","volume":"47","author":"Aukland","year":"1968","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1974.74_bb0205","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1152\/ajplegacy.1971.221.6.1621","article-title":"Measurements of intrarenal plasma flow with antiglomerular basementmembrane antibody","volume":"221","author":"Wallin","year":"1971","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1974.74_bb0210","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1152\/jappl.1972.33.5.627","article-title":"Effect of renal arterial infusion rate on distribution of radioisotopes in kidneys","volume":"33","author":"Brand","year":"1972","journal-title":"J Appl Physiol"},{"key":"10.1038\/ki.1974.74_bb0215","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1152\/ajplegacy.1972.222.1.225","article-title":"Comparative renal effects of isoncotic and colloid free volume expansion in the rat","volume":"222","author":"Daugharty","year":"1972","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1974.74_bb0220","series-title":"Physiology of the Kidney and Body Fluids","first-page":"124","author":"Pitts","year":"1968"},{"key":"10.1038\/ki.1974.74_bb0225","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1152\/ajplegacy.1969.217.4.955","article-title":"Primate kidney function in hemorrhagic shock","volume":"217","author":"Selkurt","year":"1969","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1974.74_bb0230","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1172\/JCI107179","article-title":"Renal distribution volumes of indocyanin green, [51Cr] EDTA, and 24Na in man during acute renal failure after shock","volume":"52","author":"Reubi","year":"1973","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1974.74_bb0235","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1172\/JCI105539","article-title":"The renal lesion associated with hemoglobinemia: A study of the pathogenesis of the excretory defect in the rat","volume":"46","author":"Jaenike","year":"1967","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1974.74_bb0240","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1152\/ajplegacy.1973.224.3.643","article-title":"Influence of volume expansion on single-nephron filtration rate and plasma flow in the rat","volume":"224","author":"Barrat","year":"1973","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1974.74_bb0245","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1152\/ajplegacy.1967.212.2.400","article-title":"Extravascular renal albumin","volume":"212","author":"Slotkoff","year":"1967","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1974.74_bb0250","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1152\/ajplegacy.1967.213.5.1233","article-title":"Albumin multiplier in kidney vasa recta analyzed by microspectrophometry of T-1824","volume":"213","author":"Wilde","year":"1967","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1974.74_bb0255","first-page":"435","article-title":"Extravascular protein in the kidney","volume":"27","author":"Venkatchalem","year":"1972","journal-title":"Lab Invest"},{"key":"10.1038\/ki.1974.74_bb0260","first-page":"155","article-title":"Vascular permeability of the renal medullary vessels in the mouse and rat","volume":"71","author":"Shimamura","year":"1973","journal-title":"Am J Pathol"},{"key":"10.1038\/ki.1974.74_bb0265","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1084\/jem.123.3.537","article-title":"The renal lesion associated with hemoglobinemia: II. Its structural characteristics in the rat","volume":"123","author":"Jaenike","year":"1966","journal-title":"J Exp Med"},{"key":"10.1038\/ki.1974.74_bb0270","first-page":"444","article-title":"Acute renal failure in the rat: II. Light and electron microscopic observations","volume":"18","author":"Rosen","year":"1968","journal-title":"Lab Invest"},{"key":"10.1038\/ki.1974.74_bb0275","first-page":"397","article-title":"Polymorphonuclear leukocytes and lymphopenia in acute renal failure and metabolic acidosis in the rat","volume":"45","author":"Simon","year":"1973","journal-title":"Clin Sci Mol Med"},{"key":"10.1038\/ki.1974.74_bb0280","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/BF01852215","article-title":"Prevention of mercuric chloride intoxication by temporary unilateral ureteral ligation","volume":"148","author":"Szabo","year":"1972","journal-title":"Res Exp Med (Berl)"},{"key":"10.1038\/ki.1974.74_bb0285","series-title":"General Pathology","first-page":"22","author":"Florey","year":"1970"},{"key":"10.1038\/ki.1974.74_bb0290","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1113\/jphysiol.1973.sp010303","article-title":"Relationship between the velocity of rolling granulocytes and that of the blood flow in venules","volume":"233","author":"Atherton","year":"1973","journal-title":"J Physiol"},{"key":"10.1038\/ki.1974.74_bb0295","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1038\/newbio234114a0","article-title":"Effect of prostaglandin E1 on leukocyte migration","volume":"234","author":"Kaley","year":"1971","journal-title":"Nature [New Biol]"},{"key":"10.1038\/ki.1974.74_bb0300","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1161\/01.RES.33.4.428","article-title":"Contribution of intrarenal generation of prostaglandin to autoregulation of renal blood flow in the dog","volume":"33","author":"Herbaczynska-Cedro","year":"1973","journal-title":"Circ Res"},{"key":"10.1038\/ki.1974.74_bb0305","series-title":"Studies of the Renal Circulation","author":"Trueta","year":"1947"},{"key":"10.1038\/ki.1974.74_bb0310","first-page":"543","article-title":"The vascular pattern of the rat kidney","volume":"97","author":"Moffat","year":"1963","journal-title":"J Anat"},{"key":"10.1038\/ki.1974.74_bb0315","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1126\/science.146.3652.1683","article-title":"Blood vessels of the mammalian renal medulla","volume":"146","author":"Plakke","year":"1964","journal-title":"Science"},{"key":"10.1038\/ki.1974.74_bb0320","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/BF00337120","article-title":"Der architektonische und funktionelle Aufbau der Rattenniere","volume":"82","author":"Kriz","year":"1967","journal-title":"Z Zellforsch Mikrosk Anat"},{"key":"10.1038\/ki.1974.74_bb0325","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1159\/000179347","article-title":"Structure of the arterio-glomerular units in different zones of the kidney","volume":"1","author":"Ljungqvist","year":"1964","journal-title":"Nephron"},{"key":"10.1038\/ki.1974.74_bb0330","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1159\/000179824","article-title":"The adrenergic innervation of intrarenal glomerular and extra-glomerular circulatory routes","volume":"7","author":"Ljungqvist","year":"1970","journal-title":"Nephron"},{"key":"10.1038\/ki.1974.74_bb0335","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1159\/000180142","article-title":"Nonexistence of shunts between afferent and efferent arterioles of juxtamedullary glomeruli in dog and rat kidneys","volume":"9","author":"Spinelli","year":"1972","journal-title":"Nephron"},{"key":"10.1038\/ki.1974.74_bb0340","first-page":"771","article-title":"Circulation intrar\u00e9nale dans l'intoxication mercurielle du rat \u00e9tudie par microsph\u00e8res margu\u00e9es","volume":"78","author":"Lameire","year":"1972","journal-title":"J Urol Nephrol"},{"key":"10.1038\/ki.1974.74_bb0345","unstructured":"Stein JH, Baehler RW, Cox JW, Ferris TF: Renal hemodynamic alterations during drug-induced renal vasoconstriction and acute hemorrhagic hypotension, in Conference on Acute Renal Failure, edited by Friedman EA, Eliohou HE, Washington, DC, Government Printing Office, DHEW (NIH) Pub. No. 74\u2014608, in press"},{"key":"10.1038\/ki.1974.74_bb0350","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1152\/ajplegacy.1972.223.3.682","article-title":"Limitations of 133Xe washout technique in estimation of renal blood flow","volume":"223","author":"Mowat","year":"1972","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1974.74_bb0355","unstructured":"Hollenberg NK: Vascular factors in the pathogenesis of acute renal failure in man, in Conference on Acute Renal Failure, edited by Friedman EA, Euohou HE, Washington, DC, Government Printing Office, DREW (NIH) Pub. No. 74\u2014608, in press"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815313442?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815313442?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T06:56:40Z","timestamp":1634799400000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815313442"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1974,7]]},"references-count":70,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1974,7]]}},"alternative-id":["S0085253815313442"],"URL":"https:\/\/doi.org\/10.1038\/ki.1974.74","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[1974,7]]}}}