{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:26:06Z","timestamp":1792614366646,"version":"4.5.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[1975,12,1]],"date-time":"1975-12-01T00:00:00Z","timestamp":186624000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":14616,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[1975,12]]},"DOI":"10.1038\/ki.1975.130","type":"journal-article","created":{"date-parts":[[2007,6,20]],"date-time":"2007-06-20T12:49:52Z","timestamp":1182343792000},"page":"376-384","source":"Crossref","is-referenced-by-count":62,"title":["Renal response to short-term hypocapnia in man"],"prefix":"10.1016","volume":"8","author":[{"given":"Norman","family":"Gledhill","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory J.","family":"Beirne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerome A.","family":"Dempsey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/ki.1975.130_bb0010","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1172\/JCI106973","article-title":"The nature of renal adaptation to chronic hypocapnia","volume":"51","author":"Gennari","year":"1972","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1975.130_bb0015","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1152\/jappl.1963.18.6.1155","article-title":"Respiratory control at high altitudes suggesting active transport of CSF pH","volume":"18","author":"Severinghaus","year":"1963","journal-title":"J Appl Physiol"},{"key":"10.1038\/ki.1975.130_bb0020","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1161\/01.RES.19.2.274","article-title":"Cerebral blood flow in man at high altitude: Role of cerebrospinal fluid pH in normalization of flow in chronic hypocapnia","volume":"19","author":"Severinghaus","year":"1966","journal-title":"Circ Res"},{"key":"10.1038\/ki.1975.130_bb0025","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/S0021-9258(18)74472-4","article-title":"Blood as a physicochemical system: Man at high altitudes","volume":"118","author":"Dill","year":"1937","journal-title":"J Biol Chem"},{"key":"10.1038\/ki.1975.130_bb0030","first-page":"357","article-title":"The renal response to respiratory alkalosis","volume":"11","author":"Stanbury","year":"1952","journal-title":"Clin Sci"},{"key":"10.1038\/ki.1975.130_bb0035","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1172\/JCI103449","article-title":"The renal response in man to acute experimental respiratory alkalosis and acidosis","volume":"36","author":"Barker","year":"1957","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1975.130_bb0040","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1056\/NEJM196901162800301","article-title":"Characterization and clinical application of the \u201csignificance band\u201d for acute respiratory alkalosis","volume":"280","author":"Arbus","year":"1969","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1975.130_bb0045","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0002-9343(74)90592-0","article-title":"Renal response to mechanical ventilation in patients with chronic hypercapnia","volume":"56","author":"Turino","year":"1974","journal-title":"Am J Med"},{"key":"10.1038\/ki.1975.130_bb0050","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1172\/JCI107646","article-title":"Ventilatory acclimatization to moderate hypoxemia in man: The role of spinal fluid [H+]","volume":"53","author":"Dempsey","year":"1974","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1975.130_bb0055","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1152\/jappl.1975.38.4.665","article-title":"Effects of moderate hypoxemia and hypocapnia on the regulation of CSF [H+] and ventilation in man","volume":"38","author":"Dempsey","year":"1975","journal-title":"J Appl Physiol"},{"key":"10.1038\/ki.1975.130_bb0060","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1152\/jappl.1975.38.6.1067","article-title":"Incomplete compensation of CSF [H+] in man during acclimatization to high altitude (4300 m)","volume":"38","author":"Forster","year":"1975","journal-title":"J Appl Physiol"},{"key":"10.1038\/ki.1975.130_bb0065","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/0034-5687(72)90052-7","article-title":"Control of exercise hyperpnea under varying durations of exposure to moderate hypoxia","volume":"16","author":"Dempsey","year":"1972","journal-title":"Respir Physiol"},{"key":"10.1038\/ki.1975.130_bb0070","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1152\/jappl.1972.32.1.134","article-title":"Estimation of arterial PO2, PCO2, pH and lactate from arterialized venous blood","volume":"32","author":"Forster","year":"1972","journal-title":"J Appl Physiol"},{"key":"10.1038\/ki.1975.130_bb0075","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0021-9258(18)51379-X","article-title":"Thecolorimetric determination of lactic acid in biological material","volume":"35","author":"Barker","year":"1941","journal-title":"J Biol Chem"},{"key":"10.1038\/ki.1975.130_bb0080","series-title":"Microdiffusion Analysis and Volumetric Error","author":"Conway","year":"1947"},{"key":"10.1038\/ki.1975.130_bb0085","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/S0021-9258(18)86796-5","article-title":"Applications of a new reagent for the separation of ammonia: The colorimetric determination of ammonia in urine","volume":"29","author":"Folin","year":"1917","journal-title":"J Biol Chem"},{"key":"10.1038\/ki.1975.130_bb0090","first-page":"1475","article-title":"Blood gas concentrations","volume":"2","author":"Severinghaus","year":"1965","journal-title":"Handbook of Physiology"},{"key":"10.1038\/ki.1975.130_bb0095","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/S0021-9258(18)75424-0","article-title":"Studies of acidosis: XXII. Application of the Henderson-Hasselbalch equation to human urine","volume":"106","author":"Sendroy","year":"1934","journal-title":"J Biol Chem"},{"key":"10.1038\/ki.1975.130_bb0100","doi-asserted-by":"crossref","first-page":"113","DOI":"10.3109\/00365517109086891","article-title":"Quantitation of pH regulation in hypercapnia and hypocapnia","volume":"28","author":"Siesjo","year":"1971","journal-title":"Scand J Clin Lab Invest"},{"key":"10.1038\/ki.1975.130_bb0105","series-title":"Ion Homeostasis of the Brain","first-page":"317","article-title":"Whole body buffering capacity","author":"Brown","year":"1971"},{"key":"10.1038\/ki.1975.130_bb0110","series-title":"Statistical Analysis in Psychology and Education","author":"Ferguson","year":"1959"},{"key":"10.1038\/ki.1975.130_bb0115","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/0034-5687(73)90034-0","article-title":"pH, PCO2 and PO2 of cisternal cerebrospinal fluid in high altitude natives","volume":"19","author":"Blayo","year":"1974","journal-title":"Respir Physiol"},{"key":"10.1038\/ki.1975.130_bb0120","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1152\/ajplegacy.1953.175.1.33","article-title":"Effect of plasma CO2 tension on renal tubular reabsorption of bicarbonate","volume":"175","author":"Brazeau","year":"1953","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1975.130_bb0125","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1172\/JCI102823","article-title":"The regulation of renal bicarbonate reabsorption by plasma carbon dioxide tension","volume":"32","author":"Relman","year":"1953","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1975.130_bb0130","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1172\/JCI102874","article-title":"The renal response to acute respiratory acidosis","volume":"33","author":"Dorman","year":"1954","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1975.130_bb0135","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1172\/JCI104193","article-title":"The role of plasma CO2 tension and carbonic anhydrase activity in the renal absorption of bicarbonate","volume":"39","author":"Rector","year":"1960","journal-title":"J Clin Invest"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815315386?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815315386?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T01:38:22Z","timestamp":1634780302000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815315386"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1975,12]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1975,12]]}},"alternative-id":["S0085253815315386"],"URL":"https:\/\/doi.org\/10.1038\/ki.1975.130","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[1975,12]]}}}