{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T09:14:43Z","timestamp":1759482883993,"version":"3.33.0"},"reference-count":72,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[1980,7,1]],"date-time":"1980-07-01T00:00:00Z","timestamp":331257600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":12942,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[1980,7]]},"DOI":"10.1038\/ki.1980.118","type":"journal-article","created":{"date-parts":[[2007,6,16]],"date-time":"2007-06-16T13:01:50Z","timestamp":1181998910000},"page":"125-134","source":"Crossref","is-referenced-by-count":28,"title":["Adult hemolytic-uremic syndrome"],"prefix":"10.1016","volume":"18","author":[{"given":"Liliane","family":"Morel-Maroger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1038\/ki.1980.118_bb0010","first-page":"445","article-title":"La ponction-biopsie r\u00e9nale dans les insuffisances r\u00e9nales aigu\u00ebs","volume":"129","author":"Richet","year":"1978","journal-title":"Ann M\u00e9d Interne"},{"key":"10.1038\/ki.1980.118_bb0015","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1097\/00005792-197909000-00003","article-title":"The morphology of \u201cacute tubular necrosis\u201d in man","volume":"58","author":"Solez","year":"1979","journal-title":"Medicine"},{"key":"10.1038\/ki.1980.118_bb0020","first-page":"317","article-title":"Les insuffisances r\u00e9nales d'origine vasculaire. Etude de 25 cas","volume":"78","author":"Sraer","year":"1972","journal-title":"J Urol N\u00e9phrol"},{"key":"10.1038\/ki.1980.118_bb0025","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1038\/ki.1979.70","article-title":"Prognostic importance of vascular lesions in acute renal failure with microangiopathic hemolytic anemia (hemolytic-uremic syndrome): Clinicopathologic study of 20 adults","volume":"15","author":"Morel-Maroger","year":"1979","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1980.118_bb0030","doi-asserted-by":"crossref","first-page":"248","DOI":"10.7326\/0003-4819-87-2-248_2","article-title":"Dog bite, bacteroides infection, coagulopathy, renal microangiopathy","volume":"87","author":"Fialam","year":"1977","journal-title":"Ann Intern Med"},{"key":"10.1038\/ki.1980.118_bb0035","series-title":"Prevention of Kidney and Urinary Tract Diseases","first-page":"41","article-title":"The hemolytic-uremic syndrome","author":"Habib","year":"1978"},{"key":"10.1038\/ki.1980.118_bb0040","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1056\/NEJM197804272981710","article-title":"The hemolytic-uremic syndrome is a syndrome","volume":"298","author":"Kaplan","year":"1978","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1980.118_bb0045","first-page":"905","article-title":"H\u00e4molytisch-ur\u00e4mische Syndrome: bilaterale Nie-renrindennekrosen bei akuten erworbenen h\u00e4molytischen An\u00e4mien","volume":"85","author":"Gasser","year":"1955","journal-title":"Schweiz Med Wochenschr"},{"key":"10.1038\/ki.1980.118_bb0050","first-page":"891","article-title":"Maladie thrombotique ar-teriolocapillaire du rein chez l'enfant","volume":"3","author":"Habib","year":"1958","journal-title":"Rev Fr Etud Clin Biol"},{"key":"10.1038\/ki.1980.118_bb0055","first-page":"391","article-title":"Etude anatomopathologique de 35 observations de syndrome h\u00e9molytique et ur\u00e9mique de l'enfant","volume":"26","author":"Habib","year":"1969","journal-title":"Arch Fr P\u00e9diatr"},{"key":"10.1038\/ki.1980.118_bb0060","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1159\/000179580","article-title":"Le syndrome h\u00e9molytique et ur\u00e9mique de l'enfant: Aspects cliniques et anatomiques dans 27 observations","volume":"4","author":"Habib","year":"1967","journal-title":"Nephron"},{"key":"10.1038\/ki.1980.118_bb0065","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1056\/NEJM196608042750501","article-title":"Hemolytic-uremic syndrome: clinical and pathological considerations","volume":"275","author":"Lieberman","year":"1966","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1980.118_bb0070","first-page":"627","article-title":"The hemolytic-uremic syndrome. A study of renal pathologic alterations","volume":"57","author":"Vitsky","year":"1969","journal-title":"Am J. Pathol"},{"key":"10.1038\/ki.1980.118_bb0075","series-title":"Pathology of the Kidney","first-page":"675","article-title":"Microangiopathic hemolytic anemia, hemolytic uremic syndrome, thrombotic thrombocytopenic purpura and scleroderma","author":"Heptinstall","year":"1974"},{"key":"10.1038\/ki.1980.118_bb0080","first-page":"1079","article-title":"Insuffisance r\u00e9nale aigu\u00eb avec microangiopathie thrombotique chez l'adulte","volume":"15","author":"Mery","year":"1967","journal-title":"Pathol Biol"},{"key":"10.1038\/ki.1980.118_bb0085","first-page":"423","article-title":"Irreversible postpartum renal failure. A new syndrome","volume":"37","author":"Robson","year":"1968","journal-title":"Quart J Med"},{"key":"10.1038\/ki.1980.118_bb0090","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/0002-9378(70)90307-8","article-title":"Hemolytic-uremic syndrome as a cause of postpartum renal failure","volume":"108","author":"Churg","year":"1970","journal-title":"Am J Obstet Gynecol"},{"key":"10.1038\/ki.1980.118_bb0095","first-page":"227","article-title":"The haemolytic-uraemic syndrome in adults","volume":"34","author":"Clarkson","year":"1972","journal-title":"Quart J Med"},{"key":"10.1038\/ki.1980.118_bb0100","first-page":"127","article-title":"Acute oliguric renal failure due to accelerated (malignant) hypertension","volume":"40","author":"Sevitt","year":"1971","journal-title":"Quart J Med"},{"key":"10.1038\/ki.1980.118_bb0105","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/978-3-642-66703-9_3","article-title":"Malignant nephrosclerosis in patients with hemolytic-uremic syndrome (primary malignant nephrosclerosis)","volume":"65","author":"Bohle","year":"1977","journal-title":"Curr Top Pathol"},{"key":"10.1038\/ki.1980.118_bb0110","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1159\/000180131","article-title":"Post-partum renal failure with microangiopathic haemolytic anaemia","volume":"9","author":"Ponticelli","year":"1972","journal-title":"Nephron"},{"key":"10.1038\/ki.1980.118_bb0115","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1016\/S0140-6736(73)91815-1","article-title":"Hemolytic-uremic syndrome in women taking oral contraceptives","volume":"1","author":"Brown","year":"1973","journal-title":"Lancet"},{"key":"10.1038\/ki.1980.118_bb0120","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1159\/000181648","article-title":"Hemolytic-uremic syndrome","volume":"23","author":"Goldstein","year":"1979","journal-title":"Nephron"},{"key":"10.1038\/ki.1980.118_bb0125","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1542\/peds.46.3.378","article-title":"Enteroviruses associated with the hemolytic-uremic syndrome","volume":"46","author":"Ray","year":"1970","journal-title":"Pediatrics"},{"key":"10.1038\/ki.1980.118_bb0130","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1056\/NEJM196509302731407","article-title":"Isolation of coxsackie virus group A, type 4 from a patient with hemolytic-uremic syndrome","volume":"273","author":"Glasgow","year":"1965","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1980.118_bb0135","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1056\/NEJM197804272981702","article-title":"Hemolytic-uremic syndrome after shigellosis. Relation to endotoxemia and circulating immune complexes","volume":"298","author":"Koster","year":"1978","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1980.118_bb0140","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1136\/bmj.2.5910.84","article-title":"Haemolytic-uraemic syndrome in typhoid fever","volume":"2","author":"Baker","year":"1974","journal-title":"Br Med J"},{"key":"10.1038\/ki.1980.118_bb0145","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1056\/NEJM196911062811901","article-title":"Isolation of a microtatobiote from patients with hemolytic-uremic syndrome and thrombotic thrombocytopenic purpura and from mites in the United States","volume":"281","author":"Mettler","year":"1969","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1980.118_bb0150","first-page":"272","article-title":"Acute radiation nephritis and the hemolytic-uremic syndrome","volume":"11","author":"Steele","year":"1979","journal-title":"Clin Nephrol"},{"key":"10.1038\/ki.1980.118_bb0155","doi-asserted-by":"crossref","first-page":"895","DOI":"10.7326\/0003-4819-78-6-895","article-title":"Scleroderma and microangiopathic hemolytic anemia","volume":"78","author":"Salyer","year":"1973","journal-title":"Ann Intern Med"},{"key":"10.1038\/ki.1980.118_bb0160","first-page":"153","article-title":"Human renal transplants. I. Glomerular changes","volume":"16","author":"Porter","year":"1967","journal-title":"Lab Invest"},{"key":"10.1038\/ki.1980.118_bb0165","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1111\/j.0954-6820.1971.tb04393.x","article-title":"Late renal transplant failure due to the hemolytic-uremic syndrome","volume":"189","author":"Petersen","year":"1971","journal-title":"Acta Med Scand"},{"key":"10.1038\/ki.1980.118_bb0170","first-page":"151","article-title":"Addison's disease with renal microangiopathy and renal failure (a new syndrome)","volume":"45","author":"Sachdev","year":"1977","journal-title":"Quart J Med"},{"key":"10.1038\/ki.1980.118_bb0175","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1056\/NEJM196910092811507","article-title":"Microangiopathic hemolytic anemia","volume":"281","author":"Brain","year":"1969","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1980.118_bb0180","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/0014-4800(67)90044-5","article-title":"Non lethal hemolytic and uremic syndrome in children: an electron-microscopy study of renal biopsies from six cases","volume":"7","author":"Courtecuisse","year":"1967","journal-title":"Exp Mol Pathol"},{"key":"10.1038\/ki.1980.118_bb0185","first-page":"348","article-title":"Histological changes in the renal glomerulus in essential (primary) hypertension","volume":"6","author":"McGregor","year":"1930","journal-title":"Am J Pathol"},{"key":"10.1038\/ki.1980.118_bb0190","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/S0022-3476(74)80387-2","article-title":"The hemolytic uremic syndrome with positive immunofluorescence studies","volume":"85","author":"McCoy","year":"1974","journal-title":"J Pediatr"},{"key":"10.1038\/ki.1980.118_bb0195","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1084\/jem.107.3.353","article-title":"Alterations in the blood coagulation system induced by bacterial endotoxin. I.In vivo (generalized Shwartzman reaction)","volume":"107","author":"McKay","year":"1958","journal-title":"J Exp Med"},{"key":"10.1038\/ki.1980.118_bb0200","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1111\/j.1365-2141.1962.tb06541.x","article-title":"Microangiopathic haemolytic anaemia: the possible role of vascular lesions in pathogenesis","volume":"8","author":"Brain","year":"1962","journal-title":"Br J Haematol"},{"key":"10.1038\/ki.1980.118_bb0205","first-page":"585","article-title":"Glomerular coagulation in acute ischaemic renal failure","volume":"39","author":"Clarkson","year":"1970","journal-title":"Quart J Med"},{"key":"10.1038\/ki.1980.118_bb0210","series-title":"Advances in Nephrology","first-page":"47","article-title":"The pathogenetic role of the coagulation process in glomerular diseases of immunologic origin","author":"Vassalli","year":"1971"},{"key":"10.1038\/ki.1980.118_bb0215","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1038\/ki.1975.36","article-title":"Participation of intravascular coagulation in the pathogenesis of glomerular and vascular lesions","volume":"7","author":"Kincaid-Smith","year":"1975","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1980.118_bb0220","first-page":"1966","article-title":"Thrombotic microangiopathy. Recovery of a case after heparin and magnesium therapy","volume":"2","author":"Allanby","year":"1966","journal-title":"Lancet"},{"key":"10.1038\/ki.1980.118_bb0225","first-page":"853","article-title":"Indications et limites de l'h\u00e9parinoth\u00e9rapie dans le syndrome h\u00e9molytique et ur\u00e9-mique","volume":"76","author":"Cordonnier","year":"1970","journal-title":"J Urol N\u00e9phrol"},{"key":"10.1038\/ki.1980.118_bb0230","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/S0140-6736(70)90223-0","article-title":"Heparin treatment for postpartum renal failure with microangiopathic haemolytic anaemia","volume":"2","author":"Luke","year":"1970","journal-title":"Lancet"},{"key":"10.1038\/ki.1980.118_bb0235","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0022-3476(73)80490-1","article-title":"Heparin therapy in the hemolytic uremic syndrome","volume":"83","author":"Vitacco","year":"1973","journal-title":"J Pediatr"},{"key":"10.1038\/ki.1980.118_bb0240","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/S0002-9378(16)33692-4","article-title":"Postpartum acute renal failure: recovery after heparin therapy","volume":"118","author":"Donadio","year":"1974","journal-title":"Am J Obstet Gynecol"},{"key":"10.1038\/ki.1980.118_bb0245","first-page":"169","article-title":"Has heparin changed the prognosis of the hemolytic-uremic syndrome","volume":"2","author":"Proesmans","year":"1974","journal-title":"Clin Nephrol"},{"key":"10.1038\/ki.1980.118_bb0250","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1056\/NEJM197806152982407","article-title":"Congenital deficiency of a factor in normal plasma that reverses microangiopathic hemolysis and thrombocytopenia","volume":"298","author":"Upshaw","year":"1978","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1980.118_bb0255","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/S0140-6736(78)91573-8","article-title":"Haemolytic-uremic syndrome: deficiency of plasma factor(s) regulating prostacyclin activity","volume":"2","author":"Remuzzi","year":"1978","journal-title":"Lancet"},{"key":"10.1038\/ki.1980.118_bb0260","first-page":"890","article-title":"Platelet, endothelium and renal disease","volume":"2","year":"1979","journal-title":"Lancet"},{"key":"10.1038\/ki.1980.118_bb0265","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1056\/NEJM197505222922102","article-title":"Hemolytic-uremic syndrome in families","volume":"292","author":"Kaplan","year":"1975","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1980.118_bb0270","first-page":"1773","article-title":"Famili\u00e4res h\u00e4molytisch-ur\u00e4mische Syndrom","volume":"105","author":"Blatter","year":"1975","journal-title":"Schweiz Med Wochenschr"},{"key":"10.1038\/ki.1980.118_bb0275","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/S0140-6736(74)90991-X","article-title":"Haemolytic-uraemic syndrome: evidence for intravascular C3 activation","volume":"2","author":"St\u00fchlinger","year":"1974","journal-title":"Lancet"},{"key":"10.1038\/ki.1980.118_bb0280","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1016\/S0140-6736(73)92782-7","article-title":"Serum complement levels in haemolytic-uraemic syndrome","volume":"2","author":"Kaplan","year":"1973","journal-title":"Lancet"},{"key":"10.1038\/ki.1980.118_bb0285","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/S0140-6736(73)92645-7","article-title":"Plasma C3 in haemolytic-uraemic syndrome and thrombocytic thrombocytopenic purpura","volume":"2","author":"Cameron","year":"1973","journal-title":"Lancet"},{"key":"10.1038\/ki.1980.118_bb0290","first-page":"845","article-title":"Breakdown products of C3 and factor B in hemolytic-uremic syndrome","volume":"89","author":"Kim","year":"1977","journal-title":"J Lab Clin Med"},{"key":"10.1038\/ki.1980.118_bb0295","first-page":"437","article-title":"Persistent intravascular C3 activation after bilateral nephrectomy in patients with thrombotic microangiopathy","volume":"6","author":"Kourilsky","year":"1976","journal-title":"Clin Nephrol"},{"key":"10.1038\/ki.1980.118_bb0300","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/S0022-3476(68)80427-5","article-title":"The hemolytic-uremic syndrome. Renal status of 76 patients at long-term follow-up","volume":"72","author":"Gianantonio","year":"1968","journal-title":"Pediatr"},{"key":"10.1038\/ki.1980.118_bb0305","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1177\/003693306801300505","article-title":"The haemolytic-uraemic syndrome\u2014an epidemic disease","volume":"13","author":"Ruthven","year":"1968","journal-title":"Scott Med J"},{"key":"10.1038\/ki.1980.118_bb0310","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1056\/NEJM197810192991606","article-title":"Control of hypertension and reversal of renal failure in scleroderma","volume":"299","author":"Mitrick","year":"1978","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1980.118_bb0315","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1056\/NEJM197810192991607","article-title":"Successful medical treatment of scleroderma renal crisis","volume":"299","author":"Wasner","year":"1978","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1980.118_bb0320","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1136\/bmj.1.6120.1112","article-title":"Haemolytic-uraemic syndrome and idiopathic membranous glomerulonephritis","volume":"1","author":"Dische","year":"1978","journal-title":"Br Med J"},{"key":"10.1038\/ki.1980.118_bb0325","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1038\/ki.1973.128","article-title":"Quantitative assessment of the fibrinolysis on isolated glomeruli","volume":"4","author":"Sraer","year":"1973","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1980.118_bb0330","first-page":"515","article-title":"Glomerular fibrinolytic activity after thrombin perfusion in the rat","volume":"32","author":"Sraer","year":"1975","journal-title":"Lab Invest"},{"key":"10.1038\/ki.1980.118_bb0335","first-page":"436","article-title":"Diagnosis of hemolysis and uremia in late pregnancy and puerperium: Acute tubular nephritis or thrombotic microangiopathy","volume":"13","author":"Kanfer","year":"1978","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1980.118_bb0340","first-page":"68","article-title":"Reccurrent hemolytic-uremic syndrome: A case report","volume":"4","author":"Drukker","year":"1975","journal-title":"Clin Nephrol"},{"key":"10.1038\/ki.1980.118_bb0345","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/S0031-3955(16)33359-4","article-title":"The hemolytic uremic syndrome","volume":"23","author":"Kaplan","year":"1976","journal-title":"Pediatr Clin N Am"},{"key":"10.1038\/ki.1980.118_bb0350","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0022-3476(72)80445-1","article-title":"Hemolytic-uremic syndrome","volume":"80","author":"Lieberman","year":"1972","journal-title":"J Pediatr"},{"key":"10.1038\/ki.1980.118_bb0355","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/S0022-3476(73)80178-7","article-title":"The hemolytic-uremic syndrome in California. A review of 28 non-heparinized cases with long term followup","volume":"82","author":"Tune","year":"1973","journal-title":"J Pediatr"},{"journal-title":"Short and longterm prognosis in HUS in children","year":"1975","author":"Gagnadoux","key":"10.1038\/ki.1980.118_bb0360"},{"key":"10.1038\/ki.1980.118_bb0365","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1084\/jem.149.6.1326","article-title":"Endothelial injury in scleroderma","volume":"149","author":"Kahaleh","year":"1979","journal-title":"J Exp Med"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815323310?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815323310?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T07:52:46Z","timestamp":1737100366000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815323310"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,7]]},"references-count":72,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1980,7]]}},"alternative-id":["S0085253815323310"],"URL":"https:\/\/doi.org\/10.1038\/ki.1980.118","relation":{},"ISSN":["0085-2538"],"issn-type":[{"type":"print","value":"0085-2538"}],"subject":[],"published":{"date-parts":[[1980,7]]}}}