{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T02:49:09Z","timestamp":1771642149341,"version":"3.50.1"},"reference-count":43,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[1985,11,1]],"date-time":"1985-11-01T00:00:00Z","timestamp":499651200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":10993,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[1985,11]]},"DOI":"10.1038\/ki.1985.195","type":"journal-article","created":{"date-parts":[[2007,5,31]],"date-time":"2007-05-31T13:08:20Z","timestamp":1180616900000},"page":"760-766","source":"Crossref","is-referenced-by-count":8,"title":["Net tubular secretion of bicarbonate by the alligator kidney. Antimammalian response to acetazolamide"],"prefix":"10.1016","volume":"28","author":[{"given":"Guy","family":"Lemieux","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Berkofsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9e","family":"Quenneville","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christiane","family":"Lemieux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1038\/ki.1985.195_bb0010","series-title":"Biochemistry of the Alligator","first-page":"74","author":"Coulson","year":"1964"},{"key":"10.1038\/ki.1985.195_bb0015","first-page":"F686","article-title":"Metabolic machinery of the alligator kidney","volume":"247","author":"Lemieux","year":"1984","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1985.195_bb0020","first-page":"418","article-title":"The renal excretion acid","volume":"7","author":"Pitts","year":"1948","journal-title":"Fed Proc"},{"key":"10.1038\/ki.1985.195_bb0025","series-title":"Handbook of Physiology. Renal Physiology","first-page":"455","article-title":"Production and excretion of ammonia in relation to acid-base regulation","author":"Pitts","year":"1973"},{"key":"10.1038\/ki.1985.195_bb0030","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1172\/JCI102087","article-title":"The renal regulation of acid base balance in man. IV. The nature of the renal compensation in ammonium chloride acidosis","volume":"28","author":"Sartorius","year":"1949","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1985.195_bb0035","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/ki.1982.142","article-title":"The kidney of chicken adapts to chronic metabolic acidosis. In vivo and in vitro studies","volume":"22","author":"Craan","year":"1982","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1985.195_bb0040","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1152\/ajplegacy.1968.215.3.747","article-title":"Effect of metabolic alkalosis and acidosis on tubular urate secretion in water snakes","volume":"215","author":"Dantzler","year":"1968","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1985.195_bb0045","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1152\/ajplegacy.1961.201.6.980","article-title":"Renal regulation of acid-base balance in the bullfrog","volume":"201","author":"Yoshimura","year":"1961","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1985.195_bb0050","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1172\/JCI108830","article-title":"Bicarbonate transport by rabbit cortical collecting tubules","volume":"60","author":"McKinney","year":"1977","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1985.195_bb0055","first-page":"417","article-title":"Synthesis of renal ammonium bicarbonate from 14C labeled amino acids in crocodilia","volume":"46B","author":"Hernandez","year":"1973","journal-title":"Comp Biochem Physiol"},{"key":"10.1038\/ki.1985.195_bb0060","first-page":"F446","article-title":"Quantitation of renal uric acid synthesis in the chicken","volume":"234","author":"Chin","year":"1978","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1985.195_bb0065","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1152\/ajplegacy.1976.231.4.1010","article-title":"Maleate-induced bicarbonaturia in the dog: a carbonic anhydrase-independent effect","volume":"231","author":"Gougoux","year":"1976","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1985.195_bb0070","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1038\/ki.1978.113","article-title":"Bicarbonaturic effect of lysine in the dog","volume":"14","author":"Gougoux","year":"1978","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1985.195_bb0075","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1038\/ki.1980.72","article-title":"Effect of blood pH on distal nephron hydrogen ion secretion","volume":"17","author":"Gougoux","year":"1980","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1985.195_bb0080","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1139\/y81-036","article-title":"Maintenance of glomerulotubular balance for bicarbonate during carbonic anhydrase inhibition in the dog","volume":"59","author":"Gougoux","year":"1981","journal-title":"Canad J Physiol Pharmacol"},{"key":"10.1038\/ki.1985.195_bb0085","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1038\/ki.1981.188","article-title":"Studies on the mechanism whereby acidemia stimulates collecting duct hydrogen ion secretion in vivo","volume":"20","author":"Gougoux","year":"1981","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1985.195_bb0090","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1172\/JCI107629","article-title":"Renal hemodynamics and ammoniagenesis. Characteristics of the antiluminal site for glutamine extraction","volume":"53","author":"Lemieux","year":"1974","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1985.195_bb0095","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1152\/ajplegacy.1973.224.6.1431","article-title":"Uricosuric effect of benziodarone in man and laboratory animals: a comparative study","volume":"224","author":"Lemieux","year":"1973","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1985.195_bb0100","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1139\/y82-221","article-title":"Net urate reabsorption in the Dalmatian coach hound with a note on automated measurement of urate in species with low plasma urate","volume":"60","author":"Moulin","year":"1982","journal-title":"Canad J Physiol Pharmacol"},{"key":"10.1038\/ki.1985.195_bb0105","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1159\/000179646","article-title":"The effect of renal artery constriction on tubular reabsorption of bicarbonate","volume":"5","author":"Lemieux","year":"1968","journal-title":"Nephron"},{"key":"10.1038\/ki.1985.195_bb0110","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1042\/bj0302191","article-title":"A modified colorimetric estima tion of carbonic anhydrase","volume":"30","author":"Philpot","year":"1936","journal-title":"Biochem J"},{"key":"10.1038\/ki.1985.195_bb0115","first-page":"389","article-title":"A kinetic analysis of carbonic anhydrase inhibition","volume":"130","author":"Maren","year":"1960","journal-title":"J Pharmacol Exp Therap"},{"key":"10.1038\/ki.1985.195_bb0120","unstructured":"Lemieux G, Berkofsky J, Lemieux C, Quenneville A, Lewis V: Renal ammoniagenesis by the bullfrog kidney. Effect of acidloading.Contrib Nephrol, in press"},{"key":"10.1038\/ki.1985.195_bb0125","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1152\/ajplegacy.1957.189.3.551","article-title":"Effects of prolonged administration of Diamox on excretion of acid and carbonic anhydrase and glutaminase activities in the kidney","volume":"189","author":"Seldin","year":"1957","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1985.195_bb0130","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/ki.1980.68","article-title":"Renal bicarbonate reabsorption during bicarbonate loading","volume":"17","author":"Monclair","year":"1980","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1985.195_bb0135","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1172\/JCI106269","article-title":"Regulation of renal bicarbonate reabsorption by extracellular volume","volume":"49","author":"Kurtzman","year":"1970","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1985.195_bb0140","first-page":"F484","article-title":"Effect of acetazolamide on renal bicarbonate reabsorption in volume-expanded dogs","volume":"232","author":"Jobin","year":"1977","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1985.195_bb0145","first-page":"F461","article-title":"Sodium, bicarbonate, and chloride absorption by the proximal tubule","volume":"244","author":"Rector","year":"1983","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1985.195_bb0150","first-page":"F447","article-title":"Effect of acetazolamide on bicarbonate reabsorption in the proximal tubule of the rat","volume":"237","author":"Cogan","year":"1979","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1985.195_bb0155","series-title":"Proc Am Soc of Nephrol, 17th Ann Mtg","first-page":"190A","article-title":"Two functionally distinct types of mitochondria-rich cells in cortical collecting tubule as determined by changes in cell pH in individually identified cells","author":"Schwartz","year":"1984"},{"key":"10.1038\/ki.1985.195_bb0160","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1172\/JCI109061","article-title":"Bicarbonate secretion by rabbit cortical collecting tubules in vitro","volume":"61","author":"McKinney","year":"1978","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1985.195_bb0165","doi-asserted-by":"crossref","first-page":"C259","DOI":"10.1152\/ajpcell.1983.244.3.C259","article-title":"Active electrogenic mechanisms for alkali and acid transport in turtle bladders","volume":"244","author":"Satake","year":"1983","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1985.195_bb0170","unstructured":"HOWELL BJ, RAHN H: Regulation of acid-base balance in reptiles, in Biology of the Reptilia, edited by GANS C, DAWSON WR, New York, vol. 5, 1976, Academic Press, pp 335-363"},{"key":"10.1038\/ki.1985.195_bb0175","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1152\/ajplegacy.1967.212.5.973","article-title":"Function of the excretory system of the crocodile (Crocodylus acutus)","volume":"212","author":"Schmidt-Nielsen","year":"1967","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1985.195_bb0180","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1152\/ajplegacy.1959.197.4.873","article-title":"Role of carbonic anhydrase in anion excretion in the alligator","volume":"197","author":"Coulson","year":"1957","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1985.195_bb0185","doi-asserted-by":"crossref","first-page":"606","DOI":"10.3181\/00379727-96-23552","article-title":"Effects of acetazoleamide, chlorothiazide, ad dichlorphenamide on electrolyte excretion in the alligator","volume":"96","author":"Coulson","year":"1957","journal-title":"Proc Soc Exp Biol Med"},{"key":"10.1038\/ki.1985.195_bb0190","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0010-406X(63)90098-7","article-title":"The alkaline (Marshall's) gland of the skate","volume":"10","author":"Maren","year":"1983","journal-title":"Comp Biochem Physiol"},{"key":"10.1038\/ki.1985.195_bb0195","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1152\/ajplegacy.1953.174.2.191","article-title":"Inhibition of pancreatic secretion by the carbonic anhydrase inhibitor 2-acetylamino-l,3,4-thiadiazole-5-sulfonamide, Diamox (#6063)","volume":"174","author":"Birnbaum","year":"1953","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1985.195_bb0200","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1152\/ajplegacy.1963.205.4.651","article-title":"Effects of acid-base changes and carbonic anhydrase inhibition on pancreatic secretion","volume":"205","author":"Rawls","year":"1963","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1985.195_bb0205","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1152\/ajplegacy.1968.214.5.1155","article-title":"Acid-base behavior of separated canine renal tubule cells","volume":"214","author":"Struyvenberg","year":"1968","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1985.195_bb0210","first-page":"28","article-title":"Influence of alterations in acid-base conditions on intracellular pH of intact renal cortex","volume":"6","author":"Jones","year":"1983","journal-title":"Renal Physiol"},{"key":"10.1038\/ki.1985.195_bb0215","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1242\/jeb.35.3.552","article-title":"Nitrogenous excretion in crocodiles","volume":"35","author":"Khalil","year":"1958","journal-title":"J Exp Biol"},{"key":"10.1038\/ki.1985.195_bb0220","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1152\/ajplegacy.1973.224.2.445","article-title":"Characteristics of urate transport by isolated perfused snake proximal renal tubules","volume":"224","author":"Dantzler","year":"1973","journal-title":"Am J Physiol"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815335432?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815335432?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T18:59:58Z","timestamp":1635533998000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815335432"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,11]]},"references-count":43,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1985,11]]}},"alternative-id":["S0085253815335432"],"URL":"https:\/\/doi.org\/10.1038\/ki.1985.195","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[1985,11]]}}}