{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:38:54Z","timestamp":1790739534703,"version":"4.1.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[1986,6,1]],"date-time":"1986-06-01T00:00:00Z","timestamp":517968000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":10781,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[1986,6]]},"DOI":"10.1038\/ki.1986.129","type":"journal-article","created":{"date-parts":[[2007,5,31]],"date-time":"2007-05-31T13:01:16Z","timestamp":1180616476000},"page":"1209-1214","source":"Crossref","is-referenced-by-count":130,"title":["Impaired cellular immune responses in chronic renal failure: Evidence for a T cell defect"],"prefix":"10.1016","volume":"29","author":[{"given":"Peter","family":"Kurz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"K\u00f6hler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Meuer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"H\u00fctteroth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl\u2013Hermann Meyer","family":"zum B\u00fcschenfelde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/ki.1986.129_bb0010","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0002-9343(80)90166-7","article-title":"Tuberculosis in patients with end\u2013stage renal disease","volume":"68","author":"Andrew","year":"1980","journal-title":"Am J Med"},{"key":"10.1038\/ki.1986.129_bb0015","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1159\/000182898","article-title":"Impaired humoral and cell\u2013mediated immune responses in dialyzed patients after influenza vaccination","volume":"33","author":"Cappel","year":"1983","journal-title":"Nephron"},{"key":"10.1038\/ki.1986.129_bb0020","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1038\/ki.1981.128","article-title":"Pneumococcal vaccination in patients with chronic renal disease and renal allograft recipients","volume":"20","author":"Cosio","year":"1981","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1986.129_bb0025","doi-asserted-by":"crossref","first-page":"2562","DOI":"10.1001\/jama.239.24.2562","article-title":"Influenza immunization in patients with chronic renal disease","volume":"239","author":"Ortbals","year":"1978","journal-title":"JAMA"},{"key":"10.1038\/ki.1986.129_bb0030","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1001\/archinte.1980.00330130059017","article-title":"Mycobacteriosis in patients with chronic renal failure","volume":"140","author":"Rutsky","year":"1980","journal-title":"Arch Intern Med"},{"key":"10.1038\/ki.1986.129_bb0035","first-page":"365","article-title":"Skin test sensitivity and antigen\u2013induced lymphocyte transformation in uremia","volume":"14","author":"Selroos","year":"1973","journal-title":"Clin Exp Immunol"},{"key":"10.1038\/ki.1986.129_bb0040","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1159\/000180749","article-title":"Immune system in uremia","volume":"17","author":"Dobbelstein","year":"1976","journal-title":"Nephron"},{"key":"10.1038\/ki.1986.129_bb0045","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1172\/JCI109446","article-title":"Serum inhibitor of C5 fragment\u2013mediated polymorphonuclear leukocyte chemotaxis associated with chronic hemodialysis","volume":"64","author":"Goldblum","year":"1979","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1986.129_bb0050","first-page":"636","article-title":"Humoral inhibitors of the immune response in uremia: III. The immunosuppressive factor of uremic rat serum is a very low density lipoprotein","volume":"42","author":"Raska","year":"1980","journal-title":"Lab Invest"},{"key":"10.1038\/ki.1986.129_bb0055","first-page":"288","article-title":"Depressed polymorphonuclear leukocyte functions associated with normal cytotoxic functions of T and natural killer cells during chronic hemodialysis","volume":"19","author":"Charpentier","year":"1983","journal-title":"Clin Nephrol"},{"key":"10.1038\/ki.1986.129_bb0060","first-page":"115","article-title":"Host immune status in uremia. I. Cell\u2013mediated immune mechanisms","volume":"41","author":"Miller","year":"1980","journal-title":"Clin Exp Immunol"},{"key":"10.1038\/ki.1986.129_bb0065","first-page":"123","article-title":"Host immune status in uraemia. II. Serum factors and lymphocyte transformation","volume":"41","author":"Stewart","year":"1980","journal-title":"Clin Exp Immunol"},{"key":"10.1038\/ki.1986.129_bb0070","first-page":"229","article-title":"Lymphocyte transformation in chronic renal failure","volume":"24","author":"Nakhla","year":"1973","journal-title":"Immunology"},{"key":"10.1038\/ki.1986.129_bb0075","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/ki.1976.93","article-title":"The effect of uremia and transplantation on lymphocyte subpopulations","volume":"10","author":"Quadracci","year":"1976","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1986.129_bb0080","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.4049\/jimmunol.129.3.1076","article-title":"Cellular origin of Interleukin 2 (IL 2) in man: Evidence for stimulus\u2013restricted IL 2 production by T4+ and T8+ lymphocytes","volume":"129","author":"Meuer","year":"1982","journal-title":"J Immunol"},{"key":"10.1038\/ki.1986.129_bb0085","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1002\/eji.1830100715","article-title":"Regulation of B cell immunoglobulin secretion by functional subsets of T lymphocytes in man","volume":"10","author":"Reinherz","year":"1980","journal-title":"Eur J Immunol"},{"key":"10.1038\/ki.1986.129_bb0090","doi-asserted-by":"crossref","first-page":"4061","DOI":"10.1073\/pnas.76.8.4061","article-title":"Separation of functional subsets of human T cells by a monoclonal antibody","volume":"76","author":"Reinherz","year":"1979","journal-title":"Proc Natl Acad Sci"},{"key":"10.1038\/ki.1986.129_bb0095","doi-asserted-by":"crossref","first-page":"2894","DOI":"10.4049\/jimmunol.123.6.2894","article-title":"Further characterization of the human inducer T cell subset defined by monoclonal antibody","volume":"123","author":"Reinherz","year":"1979","journal-title":"J Immunol"},{"key":"10.1038\/ki.1986.129_bb0100","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.4049\/jimmunol.120.6.2027","article-title":"T cell growth factor: Parameters of production and a quantitative microassay for activity","volume":"120","author":"Gillis","year":"1978","journal-title":"J Immunol"},{"key":"10.1038\/ki.1986.129_bb0105","doi-asserted-by":"crossref","first-page":"166","DOI":"10.7326\/0003-4819-62-1-166","article-title":"Uremia\u2014Nature's immunosuppressive device","volume":"62","author":"Lawrence","year":"1965","journal-title":"Ann Intern Med"},{"key":"10.1038\/ki.1986.129_bb0110","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1038\/ki.1984.18","article-title":"Active hepatitis B vaccination of dialysis patients and medical staff","volume":"25","author":"K\u00f6hler","year":"1984","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1986.129_bb0115","first-page":"111","article-title":"Antibody production and antigenic specific suppression to bovine serum albumin in uremic rats","volume":"48","author":"Mezzano","year":"1982","journal-title":"Clin Exp Immunol"},{"key":"10.1038\/ki.1986.129_bb0120","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1128\/iai.14.5.1138-1143.1976","article-title":"T-lymphocyte number and function and the course of hepatitis B in hemodialysis patients","volume":"14","author":"De Gast","year":"1976","journal-title":"Infect Immunity"},{"key":"10.1038\/ki.1986.129_bb0125","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1038\/ki.1982.152","article-title":"Suppressor cells assayed by numerical and functional tests in chronic renal failure","volume":"22","author":"Lortan","year":"1982","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1986.129_bb0130","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1172\/JCI106604","article-title":"Defective cellular immunity in renal failure: Depression of reactivity of lymphocytes to phytohemag-glutinin by renal failure serum","volume":"50","author":"Newberry","year":"1971","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1986.129_bb0135","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/0002-9343(84)90996-3","article-title":"Suppressor cells in end\u2013stage renal disease. Functional assays and monoclonal antibody analysis","volume":"76","author":"Raskova","year":"1984","journal-title":"Am J Med"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815337121?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815337121?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,2,14]],"date-time":"2024-02-14T17:49:28Z","timestamp":1707932968000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815337121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,6]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1986,6]]}},"alternative-id":["S0085253815337121"],"URL":"https:\/\/doi.org\/10.1038\/ki.1986.129","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[1986,6]]}}}