{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:44:32Z","timestamp":1792111472393,"version":"4.4.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[1990,4,1]],"date-time":"1990-04-01T00:00:00Z","timestamp":638928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":9381,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[1990,4]]},"DOI":"10.1038\/ki.1990.89","type":"journal-article","created":{"date-parts":[[2007,5,28]],"date-time":"2007-05-28T17:54:16Z","timestamp":1180374856000},"page":"1084-1089","source":"Crossref","is-referenced-by-count":20,"title":["Diuretic effect of bumetanide in isolated perfused kidneys of Milan hypertensive rats"],"prefix":"10.1016","volume":"37","author":[{"given":"Patricia","family":"Salvati","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romana G.","family":"Ferrario","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Bianchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/ki.1990.89_bb0010","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1097\/00001573-198609000-00009","article-title":"Ion transport across blood cell membrane in essential hypertension","volume":"1","author":"Bianchi","year":"1986","journal-title":"Curr Opinion Cardiol"},{"key":"10.1038\/ki.1990.89_bb0015","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/BF00586267","article-title":"Altered sodium permeability, calcium binding and Na, K-ATPase activity in the red blood cell membrane in essential hypertension","volume":"371","author":"Postnov","year":"1977","journal-title":"Pfl\u00fcgers Archiv"},{"key":"10.1038\/ki.1990.89_bb0020","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0140-6736(79)92891-5","article-title":"A new test showing abnormal net Na+ and K+ fluxes in erythrocytes of essential hypertensive patients","volume":"i","author":"Garay","year":"1979","journal-title":"Lancet"},{"key":"10.1038\/ki.1990.89_bb0025","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1056\/NEJM198004033021403","article-title":"Increased sodium-lithium countertransport in red cells of patients with essential hypertension","volume":"302","author":"Canessa","year":"1980","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1990.89_bb0030","doi-asserted-by":"crossref","first-page":"C385","DOI":"10.1152\/ajpcell.1984.246.5.C385","article-title":"Activation by N-ethylmale-imide of a latent K+-C1\u2212 flux in human red blood cells","volume":"246","author":"Lauf","year":"1984","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1990.89_bb0035","doi-asserted-by":"crossref","first-page":"5s","DOI":"10.1042\/cs061005s","article-title":"Membranes, ions and hypertension","volume":"61","author":"Tosteson","year":"1981","journal-title":"Clin Sci"},{"key":"10.1038\/ki.1990.89_bb0040","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1038\/284281a0","article-title":"Inherited defect in a (Na-K) cotransport system in erythrocytes from essential hypertensive patients","volume":"284","author":"Garay","year":"1980","journal-title":"Nature (London)"},{"key":"10.1038\/ki.1990.89_bb0045","doi-asserted-by":"crossref","first-page":"57s","DOI":"10.1042\/cs063057s","article-title":"Erythrocyte membrane transport systems as possible markers for essential hypertension","volume":"63","author":"Cusi","year":"1982","journal-title":"Clin Sci"},{"issue":"suppl. II","key":"10.1038\/ki.1990.89_bb0050","first-page":"S69","article-title":"Erythrocytic sodium ion transport systems in primary and secondary hypertension of the rat","volume":"21","author":"De Mendonca","year":"1982","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1990.89_bb0055","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1161\/01.HYP.7.3.319","article-title":"Red blood cell abnormalities and spontaneous hypertension in the rat. A genetically determined link","volume":"7","author":"Bianchi","year":"1985","journal-title":"Hypertension"},{"key":"10.1038\/ki.1990.89_bb0060","unstructured":"Ferrandi M, Salardi S, Parenti P, Ferrari P, Bianchi G, Braw R, Karlish SJD: Na, K, CI co-transporter mediated Rb fluxes in membrane vesicles from kidneys of normotensive and hypertensive rats. Biochem Biophys Acta (in press)"},{"key":"10.1038\/ki.1990.89_bb0065","article-title":"Sodium transport in the pathophysiology of hypertension. Abstract book of International Symposium on \u201cGenetic factors in hypertension\u201d","volume":"15","author":"Canessa","year":"1989"},{"key":"10.1038\/ki.1990.89_bb0070","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1097\/00004872-198704000-00011","article-title":"Relationship between erythrocyte volume and sodium transport in the Milan hypertensive rat and age-dependent changes","volume":"5","author":"Ferrari","year":"1987","journal-title":"J Hyperten"},{"key":"10.1038\/ki.1990.89_bb0075","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/0005-2736(85)90172-5","article-title":"Presence of a potential-sensitive Na+ transport across renal brush-border membrane vesicles from rats of the Milan hypertensive strain","volume":"819","author":"Hanozet","year":"1985","journal-title":"Biochem Biophys Acra"},{"key":"10.1038\/ki.1990.89_bb0080","doi-asserted-by":"crossref","first-page":"61s","DOI":"10.1042\/cs063061s","article-title":"Erythrocyte membrane and renal function in relation to hypertension in rats of the Milan hypertensive strain","volume":"63","author":"Ferrari","year":"1982","journal-title":"Clin Sci"},{"key":"10.1038\/ki.1990.89_bb0085","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1097\/00004872-198702000-00005","article-title":"Renal function of isolated perfused kidneys from hypertensive (MHS) and nor-motensive (MNS) rats of the Milan strain: Role of calcium","volume":"5","author":"Salvati","year":"1987","journal-title":"J Hyperten"},{"key":"10.1038\/ki.1990.89_bb0090","first-page":"F284","article-title":"Improved function with amino acids in the isolated perfused kidney","volume":"243","author":"Epstein","year":"1982","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1990.89_bb0095","series-title":"Statistical methods","article-title":"(6th ed)","author":"Snedecor","year":"1967"},{"issue":"suppl 3","key":"10.1038\/ki.1990.89_bb0100","first-page":"351","article-title":"Renal function of isolated perfused kidneys from hypertensive (MHS) and normotensive (MNS) rats of the Milan strain at different ages","volume":"2","author":"Salvati","year":"1984","journal-title":"J Hyperten"},{"key":"10.1038\/ki.1990.89_bb0105","first-page":"513","article-title":"The isolated perfused rat kidney","volume":"55","author":"Ross","year":"1978","journal-title":"Clin Sci Molec Med"},{"key":"10.1038\/ki.1990.89_bb0110","first-page":"54","article-title":"Renal function in essential hypertension","author":"Bianchi","year":"1983"},{"key":"10.1038\/ki.1990.89_bb0115","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1172\/JCI111189","article-title":"Selective vulnerability of the medullary thick ascending limb to anoxia in the isolated perfused rat kidney","volume":"73","author":"Brezis","year":"1984","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1990.89_bb0120","first-page":"327","article-title":"Transport-dependent anoxic cell injury in the isolated perfused rat kidney","volume":"116","author":"Brezis","year":"1984","journal-title":"Am J Pathol"},{"key":"10.1038\/ki.1990.89_bb0125","first-page":"F391","article-title":"Low concentration of ANP cause pressure-dependent natriuresis in the isolated kidneys","volume":"255","author":"Firth","year":"1988","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1990.89_bb0130","first-page":"1426","article-title":"Role of the renin-angiotensin system in tubuloglomerular feedback","volume":"45","author":"Schnermann","year":"1986","journal-title":"Fed Proc"},{"key":"10.1038\/ki.1990.89_bb0135","first-page":"F967","article-title":"Increased tubuloglomerular feedback activity in Milan hypertensive rats","volume":"250","author":"Boberg","year":"1986","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1990.89_bb0140","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1038\/ki.1987.277","article-title":"Molecular properties of amiloride action and of its Na+ transporting targets","volume":"32","author":"Frelin","year":"1987","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1990.89_bb0145","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/ki.1985.154","article-title":"Tubular action of diuretics: Distal effects on electrolyte transport and acidification","volume":"28","author":"Hropot","year":"1985","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1990.89_bb0150","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1152\/ajplegacy.1974.227.2.453","article-title":"Ion transport in cortical collecting tubule: Effect of amiloride","volume":"227","author":"Stoner","year":"1974","journal-title":"Am J Physiol"},{"issue":"2","key":"10.1038\/ki.1990.89_bb0155","doi-asserted-by":"crossref","first-page":"177","DOI":"10.3109\/10641968309048820","article-title":"Diuretic agents: Actions on a molecular level","volume":"A5","author":"Heidenreich","year":"1983","journal-title":"Clin Exp Hyper-Theory and Practice"},{"key":"10.1038\/ki.1990.89_bb0160","first-page":"901","article-title":"Impaired pressure-natriuresis and frusemide sensitivity in spontaneously hypertensive rats","author":"Raine","year":"1983","journal-title":"N Zealand Med J"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815348547?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815348547?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T20:02:25Z","timestamp":1635537745000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815348547"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,4]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1990,4]]}},"alternative-id":["S0085253815348547"],"URL":"https:\/\/doi.org\/10.1038\/ki.1990.89","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[1990,4]]}}}