{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T12:46:01Z","timestamp":1792500361239,"version":"4.5.0"},"reference-count":43,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[1995,4,1]],"date-time":"1995-04-01T00:00:00Z","timestamp":796694400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":7555,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[1995,4]]},"DOI":"10.1038\/ki.1995.161","type":"journal-article","created":{"date-parts":[[2007,5,21]],"date-time":"2007-05-21T17:08:07Z","timestamp":1179767287000},"page":"1130-1135","source":"Crossref","is-referenced-by-count":162,"title":["A controlled trial of cyclosporine in patients with progressive membranous nephropathy"],"prefix":"10.1016","volume":"47","author":[{"given":"Daniel C.","family":"Cattran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celia","family":"Greenwood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Ritchie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keevin","family":"Bernstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David N.","family":"Churchill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William F.","family":"Clark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter A.","family":"Morrin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Lavoie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/ki.1995.161_bb0010","first-page":"61","article-title":"The natural history of renal function in untreated idiopathic membranous glomerulonephritis in adults","volume":"22","author":"Davison","year":"1984","journal-title":"Clin Nephrol"},{"key":"10.1038\/ki.1995.161_bb0015","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1038\/ki.1988.56","article-title":"Idiopathic membranous nephropathy: The natural history of untreated patients","volume":"33","author":"Donadio","year":"1988","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1995.161_bb0020","first-page":"175","article-title":"Idiopathic membranous glomerulonephritis: Long-term follow-up in 139 cases","volume":"30","author":"Murphy","year":"1988","journal-title":"Clin Nephrol"},{"key":"10.1038\/ki.1995.161_bb0025","first-page":"67","article-title":"Long term prognosis of chronic idiopathic membranous glomerulonephritis","volume":"31","author":"Wehrmann","year":"1989","journal-title":"Clin Nephrol"},{"key":"10.1038\/ki.1995.161_bb0030","first-page":"64","article-title":"Long term prognosis of membranous nephropathy","volume":"25","author":"Kida","year":"1986","journal-title":"Clin Nephrol"},{"key":"10.1038\/ki.1995.161_bb0035","series-title":"Ninth Report of the Australian and New Zealand Combined Dialysis and Transplant Registry","author":"Disney","year":"1986"},{"key":"10.1038\/ki.1995.161_bb0040","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1056\/NEJM197912133012401","article-title":"A controlled study of short term - prednisone treatment in adults with membranous nephropathy","volume":"301","author":"Collaborative study of the adult idiopathic nephrotic syndrome","year":"1979","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1995.161_bb0045","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1056\/NEJM198901263200403","article-title":"A randomized controlled trial of prednisone in patients with idiopathic membranous nephropathy","volume":"320","author":"Cattran","year":"1989","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1995.161_bb0050","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1093\/oxfordjournals.qjmed.a068422","article-title":"Medical research council trial of short-term high dose alternate day prednisolone in idiopathic membranous nephropathy in adults","volume":"274","author":"Cameron","year":"1990","journal-title":"Quart J Med"},{"key":"10.1038\/ki.1995.161_bb0055","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1038\/ki.1974.129","article-title":"Controlled trial of cyclophosphamide in idiopathic membranous nephropathy","volume":"6","author":"Donadio","year":"1974","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1995.161_bb0060","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1056\/NEJM198404123101503","article-title":"Controlled trial of methylprednisolone and chlorambucil in idiopathic membranous nephropathy","volume":"310","author":"Ponticelli","year":"1984","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1995.161_bb0065","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1056\/NEJM198901053200102","article-title":"A randomized trial of methylprednisolone and chlorambucil in idiopathic membranous nephropathy","volume":"320","author":"Ponticelli","year":"1989","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1995.161_bb0070","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1056\/NEJM199208273270904","article-title":"Methylprednisolone plus chlorambucil as compared with methylprednisolone alone for the treatment of idiopathic membranous nephropathy","volume":"327","author":"Ponticelli","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1995.161_bb0075","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/S0140-6736(88)92470-1","article-title":"Prednisolone and chlorambucil treatment in idiopathic membranous nephropathy with deteriorating renal function","volume":"2","author":"Mathieson","year":"1988","journal-title":"Lancet"},{"key":"10.1038\/ki.1995.161_bb0080","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1016\/S0140-6736(88)90889-6","article-title":"Immunosuppression for membranous nephropathy","volume":"2","author":"Warwick","year":"1988","journal-title":"Lancet"},{"key":"10.1038\/ki.1995.161_bb0085","first-page":"929","article-title":"Methylprednisolone in patients with membranous nephropathy and declining renal function","volume":"247","author":"Short","year":"1987","journal-title":"Quart J Med"},{"key":"10.1038\/ki.1995.161_bb0090","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/ki.1987.247","article-title":"A controlled trial of cyclophosphamide in patients with membranous glomerulonephritis","volume":"32","author":"West","year":"1987","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1995.161_bb0095","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0272-6386(12)70204-4","article-title":"Long term benefits of therapy with cyclophosphamide and prednisone in patients with membranous glomerulonephritis and impaired renal function","volume":"19","author":"Jindal","year":"1992","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/ki.1995.161_bb0100","doi-asserted-by":"crossref","first-page":"438","DOI":"10.7326\/0003-4819-116-6-438","article-title":"Treatment of progressive membranous glomerulopathy. A randomized trial comparing cyclophosphamide and corticosteroids with corticosteroids alone","volume":"116","author":"Falk","year":"1992","journal-title":"Ann Intern Med"},{"key":"10.1038\/ki.1995.161_bb0105","first-page":"311","article-title":"Cyclosporin in glomerulonephritis: A pilot study","author":"Cattran","year":"1985"},{"issue":"Suppl 4","key":"10.1038\/ki.1995.161_bb0110","first-page":"280","article-title":"Fractional excretion of protein: A marker of the efficacy of cyclosporine A treatment in nephrotic syndrome","volume":"20","author":"Zietse","year":"1988","journal-title":"Transplant Proc"},{"key":"10.1038\/ki.1995.161_bb0115","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1159\/000167436","article-title":"Treatment of idiopathic membranous nephropathy unresponsive to methylprednisolone and chlorambucil with cyclosporine","volume":"7","author":"DeSanto","year":"1987","journal-title":"Am J Neprol"},{"key":"10.1038\/ki.1995.161_bb0120","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1159\/000187219","article-title":"Long term cyclosporin A therapy for severe idiopathic membranous nephropathy","volume":"63","author":"Rostoker","year":"1993","journal-title":"Nephron"},{"key":"10.1038\/ki.1995.161_bb0125","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/S0272-6386(12)70259-7","article-title":"Short-term responsiveness of membranous glomerulopathy to cyclosporine","volume":"20","author":"Guasch","year":"1992","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/ki.1995.161_bb0130","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1056\/NEJM196501282720401","article-title":"Idiopathic nephrotic syndrome in adults. A study and classification based on renal biopsies","volume":"272","author":"Churg","year":"1965","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1995.161_bb0135","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1038\/ki.1992.374","article-title":"Predicting chronic renal insufficiency in idiopathic membranous glomerulonephritis","volume":"42","author":"Pei","year":"1992","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1995.161_bb0140","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1159\/000183130","article-title":"Membranous nephropathy: Predictors of terminal renal failure","volume":"36","author":"Tu","year":"1984","journal-title":"Nephron"},{"key":"10.1038\/ki.1995.161_bb0145","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/0002-9343(79)90486-8","article-title":"Long term prognosis of idiopathic membranous glomerulonephritis","volume":"66","author":"Noel","year":"1979","journal-title":"Am J Med"},{"key":"10.1038\/ki.1995.161_bb0150","first-page":"122","article-title":"Survival in idiopathic membranous glomerulonephritis","volume":"25","author":"Honkanen","year":"1986","journal-title":"Clin Nephrol"},{"key":"10.1038\/ki.1995.161_bb0155","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1038\/ki.1985.205","article-title":"Limitations of creatinine as a filtration marker in glomerulopathic patients","volume":"28","author":"Shemesh","year":"1985","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1995.161_bb0160","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1159\/000186510","article-title":"In defense of creatinine clearance","volume":"59","author":"Giovannetti","year":"1991","journal-title":"Nephron"},{"key":"10.1038\/ki.1995.161_bb0165","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1681\/ASN.V191087","article-title":"Assessing the progression of renal disease in clinical studies: Effects of duration of follow-up and regression in the mean","volume":"1","author":"MDRD Study Group (A.S. Levy, J.J. Gassman, P.M. Hall, W.G. Walker)","year":"1991","journal-title":"J Am Soc Nephrol"},{"issue":"Suppl 1","key":"10.1038\/ki.1995.161_bb0170","first-page":"43","article-title":"Current status of cyclosporin A in the treatment of membranous, IGA and membranoproliferative glomerulonephritis","volume":"35","author":"Cattran","year":"1991","journal-title":"Clin Nephrol"},{"key":"10.1038\/ki.1995.161_bb0175","first-page":"22","article-title":"Contrasting response to cyclosporine in refractory nephrotic syndrome","volume":"31","author":"Zietse","year":"1989","journal-title":"Clin Nephrol"},{"key":"10.1038\/ki.1995.161_bb0180","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1042\/cs0820641","article-title":"Effects of cyclosporine A on glomerular barrier function in the nephrotic syndrome","volume":"82","author":"Zietse","year":"1992","journal-title":"Clin Sci"},{"key":"10.1038\/ki.1995.161_bb0185","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/S0272-6386(12)80288-5","article-title":"Enalapril can treat the proteinuria of membranous glomerulonephritis without detriment to systemic or renal hemodynamics","volume":"18","author":"Thomas","year":"1991","journal-title":"Am J Kid Dis"},{"key":"10.1038\/ki.1995.161_bb0190","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1056\/NEJM199206183262502","article-title":"Risk factors for cyclosporine-induced nephropathy in patients with autoimmune diseases","volume":"326","author":"Feutren","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1995.161_bb0195","doi-asserted-by":"crossref","first-page":"723","DOI":"10.7326\/0003-4819-114-9-725","article-title":"Sustained remission of membranous glomerulonephritis after cyclophosphamide and prednisone","volume":"114","author":"Bruns","year":"1991","journal-title":"Ann Intern Med"},{"key":"10.1038\/ki.1995.161_bb0200","first-page":"320","article-title":"The effect of treatment with prednisolone or cyclophosphamide-warfarin-dipyridamole combinations on the outcome of patients with membranous nephropathy","volume":"30","author":"Shearman","year":"1988","journal-title":"Clin Nephrol"},{"key":"10.1038\/ki.1995.161_bb0205","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0272-6386(12)80395-7","article-title":"Cyclophosphamide provides no additional benefit to steroid therapy in the treatment of idiopathic membranous nephropathy","volume":"21","author":"Alexopoulos","year":"1993","journal-title":"Am J Kid Dis"},{"key":"10.1038\/ki.1995.161_bb0210","first-page":"84","article-title":"Intravenous immunoglobulin therapy of membranous nephropathy: Efficacy and safety","volume":"35","author":"Palla","year":"1991","journal-title":"Clin Nephrol"},{"key":"10.1038\/ki.1995.161_bb0215","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1056\/NEJM199208273270911","article-title":"Membranous nephropathy\u2014still a treatment dilemma","volume":"327","author":"Cameron","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1995.161_bb0220","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1056\/NEJM199307083290211","article-title":"Idiopathic membranous nephropathy\u2014To treat or not to treat","volume":"329","author":"Lewis","year":"1993","journal-title":"N Engl J Med"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815589254?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815589254?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T22:56:57Z","timestamp":1635548217000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815589254"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,4]]},"references-count":43,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1995,4]]}},"alternative-id":["S0085253815589254"],"URL":"https:\/\/doi.org\/10.1038\/ki.1995.161","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[1995,4]]}}}