{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T06:39:35Z","timestamp":1791959975680,"version":"4.3.4"},"reference-count":30,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[1995,9,1]],"date-time":"1995-09-01T00:00:00Z","timestamp":809913600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":7402,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[1995,9]]},"DOI":"10.1038\/ki.1995.353","type":"journal-article","created":{"date-parts":[[2007,5,21]],"date-time":"2007-05-21T14:26:22Z","timestamp":1179757582000},"page":"801-805","source":"Crossref","is-referenced-by-count":38,"title":["Decreased frequency of HLA-DR13DR6 in Wegener's granulomatosis"],"prefix":"10.1016","volume":"48","author":[{"given":"E. Christiaan","family":"Hagen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coen A.","family":"Stegeman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe","family":"D'Amaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geziena M.T.","family":"Schreuder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon P.M.","family":"Lems","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan Willem","family":"Cohen Tervaert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gijs MTh","family":"de Jong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald J.","family":"Hen\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cees G.M.","family":"Kallenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed R.","family":"Daha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fokko J.","family":"van der Woude","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/ki.1995.353_bb0010","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/art.1780370206","article-title":"Nomenclature of systemic vasculitides: The proposal of an international consensus conference","volume":"37","author":"Jennette","year":"1994","journal-title":"Arthritis Rheum"},{"key":"10.1038\/ki.1995.353_bb0015","first-page":"533","article-title":"Wegener's granulomatosis: Pathology and review of the literature","volume":"58","author":"Godman","year":"1954","journal-title":"Arch Pathol"},{"key":"10.1038\/ki.1995.353_bb0020","first-page":"1","article-title":"Critical re-evaluation of 41 cases of idiopathic crescentic glomerulonephritis","volume":"41","author":"Ferrario","year":"1994","journal-title":"Clin Nephrol"},{"key":"10.1038\/ki.1995.353_bb0025","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/S0140-6736(85)91147-X","article-title":"Autoantibodies against neutrophils and monocytes: Tool for diagnosis and marker of disease activity in Wegener's granulomatosis","volume":"1","author":"Van Der Woude","year":"1985","journal-title":"Lancet"},{"key":"10.1038\/ki.1995.353_bb0030","first-page":"731","article-title":"Renal disease associated with circulating antineutrophil cytoplasm activity","volume":"85","author":"Garrett","year":"1992","journal-title":"Quart J Med"},{"key":"10.1038\/ki.1995.353_bb0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/ki.1994.239","article-title":"Anti-neutrophil cytoplasmic antibodies: Current diagnostic and pathophysiological potential","volume":"46","author":"Kallenberg","year":"1994","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1995.353_bb0040","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S0272-6386(12)80878-X","article-title":"Diagnostic classification of antineutrophil cytoplasmic autoantibody-associated vasculitides","volume":"18","author":"Jennette","year":"1991","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/ki.1995.353_bb0045","doi-asserted-by":"crossref","first-page":"4115","DOI":"10.1073\/pnas.87.11.4115","article-title":"Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro","volume":"87","author":"Falk","year":"1990","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/ki.1995.353_bb0050","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1111\/j.1365-2249.1993.tb08192.x","article-title":"Relevance of classic anti-neutrophil cytoplasmic autoantibody (c-ANCA)-mediated inhibition of proteinase 3-alpha1-antitrypsin complexation to disease activity in Wegener's granulomatosis","volume":"93","author":"Dolman","year":"1993","journal-title":"Clin Exp Immunol"},{"key":"10.1038\/ki.1995.353_bb0055","first-page":"169","article-title":"The role of the c-ANCA antigen in the pathogenesis of Wegener's granulomatosis a hypothesis based on both humoral and cellular mechanisms","volume":"36","author":"Van Der Woude","year":"1990","journal-title":"Neth J Med"},{"key":"10.1038\/ki.1995.353_bb0060","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1006\/jaut.1993.1020","article-title":"Cellular immune responses and pathogenesis in c-ANCA positive vasculitides","volume":"6","author":"Rasmussen","year":"1993","journal-title":"J Autoimmun"},{"key":"10.1038\/ki.1995.353_bb0065","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1111\/j.1365-2249.1994.tb05511.x","article-title":"T-cell reactivity to proteinase 3 and myeloperoxidase in patients with Wegener's granulomatosis","volume":"98","author":"Brouwer","year":"1994","journal-title":"Clin Exp Immunol"},{"key":"10.1038\/ki.1995.353_bb0070","unstructured":"BALLIEUX BEPB, VAN DEN BURGG SH, HAGEN EC, VAN DER WOUDE FJ, MELIEF CJM, VAN ES LA, DAHA MR: Cell-mediated autoimmunity in patients with Wegener's granulomatosis. Clin Exp Immunol (in press)"},{"key":"10.1038\/ki.1995.353_bb0075","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1002\/art.1780260118","article-title":"HLA antigen frequencies in systemic vasculitis: Increase in HLA-DR2 in Wegener's granulomatosis","volume":"26","author":"Elkon","year":"1983","journal-title":"Arthritis Rheum"},{"key":"10.1038\/ki.1995.353_bb0080","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/0090-1229(79)90150-8","article-title":"Association of Wegener's granulomatosis with HLA-B8","volume":"14","author":"Katz","year":"1979","journal-title":"Clin Immunol Immunopathol"},{"key":"10.1038\/ki.1995.353_bb0085","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1038\/ki.1992.161","article-title":"HLA class II specificities in vasculitis with antibodies to neutrophil cytoplasmic antigens","volume":"41","author":"Spencer","year":"1992","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1995.353_bb0090","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1136\/ard.51.2.246","article-title":"Association of Wegener's granulomatosis with HLA antigens and other genetic markers","volume":"51","author":"Papiha","year":"1992","journal-title":"Ann Rheum Dis"},{"key":"10.1038\/ki.1995.353_bb0095","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1111\/j.1399-0039.1978.tb01236.x","article-title":"Hla-a antigens of patients with Wegener's granulomatosis","volume":"11","author":"Strimlan","year":"1978","journal-title":"Tissue Antigens"},{"key":"10.1038\/ki.1995.353_bb0100","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/BF00453639","article-title":"The spectrum of histocompatibility antigens (Hla) in Wegener's granulomatosis","volume":"233","author":"Beigel","year":"1981","journal-title":"Arch Otorhinolaryngol"},{"key":"10.1038\/ki.1995.353_bb0105","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1111\/j.1365-2273.1991.tb01037.x","article-title":"Hla antigen frequencies and Wegener's granulomatosis","volume":"16","author":"Murty","year":"1991","journal-title":"Clin Otolaryngol"},{"key":"10.1038\/ki.1995.353_bb0110","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1038\/ki.1995.37","article-title":"Distribution of MHC class II alleles in primary systemic vasculitis","volume":"47","author":"Zhang","year":"1995","journal-title":"Kidney Int"},{"issue":"Suppl","key":"10.1038\/ki.1995.353_bb0115","first-page":"12","article-title":"Delineation of a standard procedure for indirect immunofluorescence detection of ANCA","volume":"6","author":"Wiik","year":"1989","journal-title":"Apmis"},{"key":"10.1038\/ki.1995.353_bb0120","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/j.1469-1809.1955.tb01348.x","article-title":"On estimating the relation between blood groups and disease","volume":"19","author":"Woolf","year":"1955","journal-title":"Ann Hum Genet"},{"key":"10.1038\/ki.1995.353_bb0125","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1111\/j.1469-1809.1955.tb01285.x","article-title":"The estimation and significance of the logarithm of the ratio of frequencies","volume":"20","author":"Haldane","year":"1955","journal-title":"Ann Hum Genet"},{"key":"10.1038\/ki.1995.353_bb0130","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/j.1744-313X.1974.tb00312.x","article-title":"HLA and disease. The detection of associations","volume":"1","author":"Edwards","year":"1974","journal-title":"J Immunogenetics"},{"key":"10.1038\/ki.1995.353_bb0135","doi-asserted-by":"crossref","first-page":"1996","DOI":"10.1182\/blood.V81.8.1996.1996","article-title":"Anti-neutrophil cytoplasmic autoantibodies (ANCA). A review of the antigens involved, the assays, the clinical and possible pathogenetic consequenses","volume":"81","author":"Hagen","year":"1993","journal-title":"Blood"},{"key":"10.1038\/ki.1995.353_bb0140","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1159\/000166898","article-title":"Clinical and immunological follow-up of patients with severe renal disease in wegener's granulomatosis","volume":"5","author":"Ten Berge","year":"1985","journal-title":"Am J Nephrol"},{"key":"10.1038\/ki.1995.353_bb0145","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/0090-1229(92)90005-9","article-title":"T and B cell responses to neutrophil cytoplasmic antigens in systemic vasculitis","volume":"63","author":"Mathieson","year":"1992","journal-title":"Clin Immunol Immunopathol"},{"key":"10.1038\/ki.1995.353_bb0150","first-page":"638","article-title":"Insulin-dependent diabetes mellitus","author":"Svejgaard","year":"1980"},{"key":"10.1038\/ki.1995.353_bb0155","first-page":"713","article-title":"HLA class II associations in insulin-dependent diabetes mellitus among Blacks, Cauca-soids, and Japanese","author":"Ronningen","year":"1992"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815591254?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815591254?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T23:06:34Z","timestamp":1635548794000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815591254"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,9]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1995,9]]}},"alternative-id":["S0085253815591254"],"URL":"https:\/\/doi.org\/10.1038\/ki.1995.353","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[1995,9]]}}}