{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T17:13:04Z","timestamp":1771866784182,"version":"3.50.1"},"reference-count":39,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[1995,10,1]],"date-time":"1995-10-01T00:00:00Z","timestamp":812505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":7372,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[1995,10]]},"DOI":"10.1038\/ki.1995.399","type":"journal-article","created":{"date-parts":[[2007,5,21]],"date-time":"2007-05-21T14:46:22Z","timestamp":1179758782000},"page":"1158-1166","source":"Crossref","is-referenced-by-count":16,"title":["Role of growth factors in mesangial cell ion channel regulation"],"prefix":"10.1016","volume":"48","author":[{"given":"Brian N.","family":"Ling","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Matsunaga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heping","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas C.","family":"Eaton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1038\/ki.1995.399_bb0010","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1038\/ki.1994.41","article-title":"The mesangial cell: A tissue culture view","volume":"45","author":"Davies","year":"1994","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1995.399_bb0015","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1152\/physrev.1989.69.4.1347","article-title":"Physiology of mesangial cell","volume":"69","author":"Mene","year":"1989","journal-title":"Physiol Rev"},{"key":"10.1038\/ki.1995.399_bb0020","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1038\/ki.1993.39","article-title":"Growth factors in glomerulonephritis","volume":"43","author":"Abboud","year":"1993","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1995.399_bb0025","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1681\/ASN.V391531","article-title":"Angiotensin II as a renal growth factor","volume":"3","author":"Wolf","year":"1993","journal-title":"JASN"},{"key":"10.1038\/ki.1995.399_bb0030","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1681\/ASN.V42119","article-title":"Role of plateletderived growth factor in glomerular disease","volume":"4","author":"Johnson","year":"1993","journal-title":"JASN"},{"issue":"Suppl 32","key":"10.1038\/ki.1995.399_bb0035","first-page":"S65","article-title":"Mesangial cell function and chloride ions","volume":"32","author":"Okuda","year":"1991","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1995.399_bb0040","first-page":"A390","article-title":"G protein activates PDGF-induced Ca2+-permeable channel in mesangial cells","volume":"9","author":"Ma","year":"1995","journal-title":"FASEB J"},{"key":"10.1038\/ki.1995.399_bb0045","doi-asserted-by":"crossref","first-page":"C456","DOI":"10.1152\/ajpcell.1994.267.2.C456","article-title":"Ca2+-permeable channel associated with platelet-derived growth factor receptor in mesangial cells","volume":"267","author":"Matsunaga","year":"1994","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1995.399_bb0050","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1172\/JCI116815","article-title":"Regulation of mesangial cell ion channels by insulin and angiotensin II: Possible role in diabetic glomerular hyperfiltration","volume":"92","author":"Ling","year":"1993","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1995.399_bb0055","first-page":"873","article-title":"On the mechanism of activation of Ca2+-permeable channels by PDGF in mesangial cells: involvement of GTP-binding protein and tyrosine kinase","volume":"4","author":"Matsunaga","year":"1993","journal-title":"JASN"},{"key":"10.1038\/ki.1995.399_bb0060","first-page":"114A","article-title":"High glucose reduces the responsiveness of mesangial cell (MC) ion channels to angiotensin II (AII), despite the presence of insulin","volume":"42","author":"Ling","year":"1994","journal-title":"Clin Res"},{"key":"10.1038\/ki.1995.399_bb0065","first-page":"872","article-title":"Cyclosporine A augments endothelin 1-induced activation of Cl- and nonselective cation channels (NSCC) in rat mesangial cells","volume":"4","author":"Ling","year":"1993","journal-title":"JASN"},{"key":"10.1038\/ki.1995.399_bb0070","first-page":"872","article-title":"Cl- influx via a furosemide-sensitive pathway modulates Cl- efflux via Ca2+-dependent Cl- channels in glomerular mesangial cells","volume":"4","author":"Ling","year":"1993","journal-title":"JASN"},{"key":"10.1038\/ki.1995.399_bb0075","first-page":"73","article-title":"Ion channels in epithelial tissue: Single-channel properties","author":"Eaton","year":"1992"},{"key":"10.1038\/ki.1995.399_bb0080","first-page":"H1827","article-title":"Ca2+-dependent and Ca2+-permeable ion channels in aortic endothelial cells","volume":"263","author":"Ling","year":"1992","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1995.399_bb0085","doi-asserted-by":"crossref","first-page":"3300","DOI":"10.1096\/fasebj.4.15.2147667","article-title":"Control of the renal vasculature by vasoactive peptides","volume":"4","author":"Carmines","year":"1990","journal-title":"FASEB J"},{"key":"10.1038\/ki.1995.399_bb0090","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1172\/JCI114373","article-title":"Ambient Cl- ions modify rat mesangial cell contraction by modulating cell inositol trisphosphate and Ca2+ via enhanced prostaglandin E2","volume":"84","author":"Okuda","year":"1989","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1995.399_bb0095","first-page":"F668","article-title":"Multiple signaling pathways for Cl--dependent depolarization of mesangial cells: Role of Ca2+, PKC, and G proteins","volume":"262","author":"Kremer","year":"1992","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1995.399_bb0100","first-page":"96","article-title":"Calcium channel current in cultured rat mesangial cells","volume":"43","author":"Nishio","year":"1993","journal-title":"Mol Pharmacol"},{"key":"10.1038\/ki.1995.399_bb0105","first-page":"F808","article-title":"Ion channel activities of cultured rat mesangial cells","volume":"261","author":"Matsunaga","year":"1991","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1995.399_bb0110","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1681\/ASN.V351064","article-title":"Insulin resistance, hyperinsulinemia, and obesity-associated hypertension","volume":"3","author":"Brands","year":"1992","journal-title":"JASN"},{"key":"10.1038\/ki.1995.399_bb0115","doi-asserted-by":"crossref","first-page":"4190","DOI":"10.1073\/pnas.79.13.4190","article-title":"Insulin requirement for contraction of cultured rat glomerular mesangial cells in response to angiotensin II: Possible role for insulin in modulating glomerular hemodynamics","volume":"79","author":"Kreisberg","year":"1982","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/ki.1995.399_bb0120","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1042\/bj2720561","article-title":"Insulin-dependent contractility of glomerular mesangial cells in response to angiotensin II, platelet-activating factor and endothelin is attenuated by prostaglandin E2","volume":"272","author":"Dunlop","year":"1990","journal-title":"Biochem J"},{"key":"10.1038\/ki.1995.399_bb0125","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1681\/ASN.V22179","article-title":"Effects of glucose on receptor-mediated phosphoinositide hydrolysis and second messenger generation in rat glomerular mesangial cells","volume":"2","author":"Guzman","year":"1991","journal-title":"JASN"},{"key":"10.1038\/ki.1995.399_bb0130","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.2337\/diab.41.9.1165","article-title":"Identification and characterization of aldose reductase in cultured rat mesangial cells","volume":"41","author":"Kikkawa","year":"1992","journal-title":"Diabetes"},{"key":"10.1038\/ki.1995.399_bb0135","first-page":"67","article-title":"Amelioration of glomerular hyperfiltration in acute experimental diabetes mellitus by dietary myo-inositol supplementation and aldose reductase inhibition","volume":"99","author":"Goldfarb","year":"1986","journal-title":"Trans Assoc Am Phys"},{"key":"10.1038\/ki.1995.399_bb0140","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1056\/NEJM199307293290502","article-title":"The effect of long-term intensified insulin treatment on the development of microvascular complications of diabetes mellitus","volume":"329","author":"Reichard","year":"1993","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1995.399_bb0145","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1038\/ki.1992.126","article-title":"Increased glomerular filtration rate as a predictor of diabetic nephropathy-An 8-year prospective study","volume":"41","author":"Rudberg","year":"1992","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1995.399_bb0150","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1038\/ki.1991.277","article-title":"Mechanisms of diabetic hyperfiltration","volume":"40","author":"Bank","year":"1991","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1995.399_bb0155","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1146\/annurev.ph.55.030193.001513","article-title":"Role of growth factors in regulation of renal growth","volume":"55","author":"Hammerman","year":"1993","journal-title":"Ann Rev Physiol"},{"key":"10.1038\/ki.1995.399_bb0160","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1038\/ki.1991.159","article-title":"Additive and synergistic effects of cyclosporine metabolites on glomerular mesangial cells","volume":"39","author":"Radeke","year":"1991","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1995.399_bb0165","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1038\/ki.1992.245","article-title":"Endothelin-1 receptor antagonist: Effects on endothelin- and cyclosporine-treated mesangial cells","volume":"42","author":"Takeda","year":"1992","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1995.399_bb0170","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/0002-8703(93)90208-Q","article-title":"Manidipine inhibits endothelin-1-induced [Ca2+]i signaling but potentiates endothelin's effect on c-fos and c-jun induction in vascular smooth muscle and glomerular mesangial cells","volume":"125","author":"Huang","year":"1993","journal-title":"Am Heart J"},{"key":"10.1038\/ki.1995.399_bb0175","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1038\/ki.1993.339","article-title":"Cyclosporine A inhibits apical secretory K+ channels in rabbit cortical collecting tubule prinicpal cells","volume":"44","author":"Ling","year":"1993","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1995.399_bb0180","doi-asserted-by":"crossref","first-page":"351","DOI":"10.2337\/diab.42.2.351","article-title":"Insulin stimulates production and secretion of endothelin from bovine endothelial cells","volume":"42","author":"Hu","year":"1993","journal-title":"Diabetes"},{"key":"10.1038\/ki.1995.399_bb0185","doi-asserted-by":"crossref","first-page":"17613","DOI":"10.1016\/S0021-9258(18)38208-5","article-title":"Agonist stimulation of Na+\/K+\/Cl- cotransport in rat glomerular mesangial cells","volume":"265","author":"Homma","year":"1990","journal-title":"J Biol Chem"},{"key":"10.1038\/ki.1995.399_bb0190","first-page":"321","article-title":"Influence of furosemide on rubidium-86 uptake and alpha-adrenergic responsiveness of arterial smooth muscle","volume":"24","author":"Deth","year":"1987","journal-title":"Blood Vessels"},{"key":"10.1038\/ki.1995.399_bb0195","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1038\/ki.1983.72","article-title":"Hemodynamically mediated glomerular injury and the progressive nature of kidney disease","volume":"23","author":"Brenner","year":"1983","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1995.399_bb0200","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1038\/ki.1988.87","article-title":"Focal and segmental glomerulosclerosis: Analogies to atherosclerosis","volume":"33","author":"Diamond","year":"1988","journal-title":"Kidney Int"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815591710?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815591710?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T23:08:57Z","timestamp":1635548937000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815591710"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,10]]},"references-count":39,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1995,10]]}},"alternative-id":["S0085253815591710"],"URL":"https:\/\/doi.org\/10.1038\/ki.1995.399","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[1995,10]]}}}