{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T13:01:24Z","timestamp":1791896484650,"version":"4.3.4"},"reference-count":37,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[1996,2,1]],"date-time":"1996-02-01T00:00:00Z","timestamp":823132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":7249,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[1996,2]]},"DOI":"10.1038\/ki.1996.76","type":"journal-article","created":{"date-parts":[[2007,5,21]],"date-time":"2007-05-21T12:39:06Z","timestamp":1179751146000},"page":"534-537","source":"Crossref","is-referenced-by-count":40,"title":["Genetic risk for renal artery stenosis: Association with deletion polymorphism in angiotensin 1-converting enzyme gene"],"prefix":"10.1016","volume":"49","author":[{"given":"Constantinos G.","family":"Missouris","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline","family":"Barley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve","family":"Jeffery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas D.","family":"Carter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald R.J.","family":"Singer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graham A.","family":"MacGregor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/ki.1996.76_bb0010","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/0002-9343(94)90109-0","article-title":"Renal artery stenosis: A common and important problem in patients with peripheral vascular disease","volume":"96","author":"Missouris","year":"1994","journal-title":"Am J Med"},{"key":"10.1038\/ki.1996.76_bb0015","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1016\/0140-6736(93)90911-Y","article-title":"Renal artery stenosis and prediction of risk of vascular surgery","volume":"341","author":"Missouris","year":"1993","journal-title":"Lancet"},{"key":"10.1038\/ki.1996.76_bb0020","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1161\/01.CIR.20.4.520","article-title":"Autopsy studies in atherosclerosis","volume":"XX","author":"Roberts","year":"1959","journal-title":"Circulation"},{"key":"10.1038\/ki.1996.76_bb0025","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1038\/ng1293-324","article-title":"A potent genetic risk factor for restenosis","volume":"5","author":"Ohishi","year":"1993","journal-title":"Nature Genet"},{"key":"10.1038\/ki.1996.76_bb0030","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1136\/hrt.72.2.101","article-title":"Are polymorphisms in the ACE gene a potent genetic risk factor for restenosis","volume":"72","author":"Kaski","year":"1994","journal-title":"Brit Heart J"},{"key":"10.1038\/ki.1996.76_bb0035","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1038\/359641a0","article-title":"Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction","volume":"359","author":"Cambien","year":"1992","journal-title":"Nature"},{"key":"10.1038\/ki.1996.76_bb0040","first-page":"635","article-title":"Angiotensin-1 converting enzyme (ACE) polymorphism in patients presenting with myocardial infarction or unstable angina","volume":"8","author":"Leatham","year":"1994","journal-title":"J Hum Hypertens"},{"key":"10.1038\/ki.1996.76_bb0045","doi-asserted-by":"crossref","first-page":"2120","DOI":"10.1161\/01.CIR.91.8.2120","article-title":"Angiotensin-converting enzyme gene polymorphism is associated with myocardial infarction but not with development of coronary stenosis","volume":"91","author":"Ludwig","year":"1995","journal-title":"Circulation"},{"key":"10.1038\/ki.1996.76_bb0050","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1161\/01.HYP.18.4.558","article-title":"Ramiprilat enhances endothelial autacoid formation by inhibiting breakdown of endothelium-derived bradykinin","volume":"18","author":"Wiemer","year":"1991","journal-title":"Hypertension"},{"key":"10.1038\/ki.1996.76_bb0055","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1097\/00004872-199109010-00003","article-title":"Angiotensin 2 stimulates collagen synthesis in cultured vascular smooth muscle cells","volume":"9","author":"Kato","year":"1991","journal-title":"J Hypertens"},{"key":"10.1038\/ki.1996.76_bb0060","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1161\/01.RES.68.2.450","article-title":"Angiotensin II induces smooth muscle cell proliferation in the normal and injured rat arterial wall","volume":"68","author":"Daeman","year":"1991","journal-title":"Circ Res"},{"key":"10.1038\/ki.1996.76_bb0065","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1126\/science.2526370","article-title":"Inhibitors of angiotensin-converting enzyme myointimal proliferation after vascular injury","volume":"245","author":"Powell","year":"1989","journal-title":"Science"},{"key":"10.1038\/ki.1996.76_bb0070","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/S0006-291X(05)80142-1","article-title":"Kinins mediate the antiproliferative effect of ramipril in rat carotid artery","volume":"182","author":"Farhy","year":"1992","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1038\/ki.1996.76_bb0075","doi-asserted-by":"crossref","first-page":"2048","DOI":"10.1161\/01.CIR.83.6.2048","article-title":"Mechanisms of coronary vasodilation produced by bradykinin","volume":"83","author":"Pelc","year":"1991","journal-title":"Circulation"},{"key":"10.1038\/ki.1996.76_bb0080","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1172\/JCI114844","article-title":"An insertion\/deletion polymorphism in the angiotensin 1 converting enzyme gene accounting for half the variance of serum enzyme levels","volume":"86","author":"Rigat","year":"1990","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1996.76_bb0085","doi-asserted-by":"crossref","first-page":"9386","DOI":"10.1073\/pnas.85.24.9386","article-title":"Two putative active centers in human angiotensin 1 converting enzyme revealed by molecular cloning","volume":"85","author":"Soubrier","year":"1988","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/ki.1996.76_bb0090","doi-asserted-by":"crossref","first-page":"283","DOI":"10.2214\/ajr.104.2.283","article-title":"The location of the renal arteries. An angiographic and post-mortem study","volume":"104","author":"Odman","year":"1968","journal-title":"Am J Roentgenol"},{"key":"10.1038\/ki.1996.76_bb0095","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1136\/hrt.37.8.804","article-title":"Clinical experience with use of ultrasound sphygmomanometer","volume":"37","author":"George","year":"1975","journal-title":"Brit Heart J"},{"key":"10.1038\/ki.1996.76_bb0100","first-page":"197","article-title":"Evidence from combined segregation and linkage analysis, that a variant of the angiotensin-1 converting gene controls plasma ACE levels","volume":"51","author":"Tiret","year":"1992","journal-title":"Am J Hum Genet"},{"key":"10.1038\/ki.1996.76_bb0105","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1101\/gr.3.2.120","article-title":"Mistyping ACE heterozygotes","volume":"3","author":"Shanmugan","year":"1993","journal-title":"PCR Meth Appl"},{"key":"10.1038\/ki.1996.76_bb0110","first-page":"211","article-title":"Polymorphisms of the angiotensin-converting-enzyme gene in subjects who die from coronary heart disease","volume":"87","author":"Evans","year":"1994","journal-title":"Quart J Med"},{"key":"10.1038\/ki.1996.76_bb0115","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1177\/000456328502200218","article-title":"A continuous monitoring spectrophotometric method for the measurement of angiotensin converting enzyme in human serum","volume":"22","author":"MacGuire","year":"1985","journal-title":"Annal Clin Biochem"},{"key":"10.1038\/ki.1996.76_bb0120","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1056\/NEJM199406093302302","article-title":"Association between a deletion polymorphism of the angiotensin-converting-enzyme gene and left ventricular hypertrophy","volume":"330","author":"Schunkert","year":"1994","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1996.76_bb0125","doi-asserted-by":"crossref","first-page":"2622","DOI":"10.1161\/01.CIR.90.6.2622","article-title":"DD genotype of the angiotensin-converting-enzyme gene is a risk factor for left ventricular hypertrophy","volume":"90","author":"Iwai","year":"1994","journal-title":"Circulation"},{"key":"10.1038\/ki.1996.76_bb0130","doi-asserted-by":"crossref","first-page":"136A","DOI":"10.1016\/0735-1097(95)92021-V","article-title":"Deletion polymorphism of the angiotensin converting enzyme gene is associated with concentric remodelling of the left ventricle","volume":"25","author":"Gharavi","year":"1995","journal-title":"J Am Coll Cardiol"},{"key":"10.1038\/ki.1996.76_bb0135","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/0140-6736(93)92061-W","article-title":"Angiotensin-converting enzyme DD genotype in patients with ischaemic or dilated cardiomyopathy","volume":"342","author":"Raynolds","year":"1993","journal-title":"Lancet"},{"key":"10.1038\/ki.1996.76_bb0140","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/0140-6736(93)92064-Z","article-title":"Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death","volume":"342","author":"Marian","year":"1993","journal-title":"Lancet"},{"key":"10.1038\/ki.1996.76_bb0145","doi-asserted-by":"crossref","first-page":"690","DOI":"10.2337\/diab.43.5.690","article-title":"Genetic predisposition to diabetic nephropathy","volume":"43","author":"Doria","year":"1994","journal-title":"Diabetes"},{"key":"10.1038\/ki.1996.76_bb0150","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1056\/NEJM199503163321103","article-title":"A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease","volume":"332","author":"Lindpaintner","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1996.76_bb0155","doi-asserted-by":"crossref","first-page":"136A","DOI":"10.1016\/0735-1097(95)92019-2","article-title":"Left ventricular hypertrophy and the deletion-insertion polymorphism of the angiotensin converting enzyme gene","volume":"25","author":"Levy","year":"1995","journal-title":"J Am Coll Cardiol"},{"key":"10.1038\/ki.1996.76_bb0160","first-page":"459","article-title":"Angiotensin-converting-enzyme genotype and ischemic heart disease","volume":"333","author":"Lindpaintner","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1996.76_bb0165","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1097\/00004872-199408000-00014","article-title":"Angiotensin converting enzyme insertion\/deletion polymorphism: Association with ethnic origin","volume":"12","author":"Barley","year":"1994","journal-title":"J Hypertens"},{"key":"10.1038\/ki.1996.76_bb0170","first-page":"701","article-title":"Angiotensin 1 converting enzyme I\/D polymorphism: Blood pressure and the renin-angiotensin system in Caucasians and Afro-Carribeans","volume":"9","author":"Sagnella","year":"1995","journal-title":"J Hum Hypertens"},{"key":"10.1038\/ki.1996.76_bb0175","first-page":"774","article-title":"Familial resemblance of plasma angiotensin converting enzyme level: The Nancy study","volume":"43","author":"Cambien","year":"1988","journal-title":"Am J Hum Genet"},{"key":"10.1038\/ki.1996.76_bb0180","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1038\/ng0492-72","article-title":"Absence of linkage between the angiotensin converting enzyme locus and human essential hypertension","volume":"1","author":"Jeunemaitre","year":"1992","journal-title":"Nature Genet"},{"key":"10.1038\/ki.1996.76_bb0185","first-page":"492","article-title":"Hypertension in a family practice","volume":"117","author":"Rudnick","year":"1977","journal-title":"Can Med Assoc J"},{"key":"10.1038\/ki.1996.76_bb0190","doi-asserted-by":"crossref","first-page":"170","DOI":"10.2307\/3349261","article-title":"Evaluation of the hypertensive patient with emphasis on detecting curable causes","volume":"37","author":"Gifford","year":"1969","journal-title":"Milbank Med Found Quart"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815593708?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815593708?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T23:34:52Z","timestamp":1635550492000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815593708"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,2]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1996,2]]}},"alternative-id":["S0085253815593708"],"URL":"https:\/\/doi.org\/10.1038\/ki.1996.76","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[1996,2]]}}}