{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T21:05:00Z","timestamp":1790888700821,"version":"4.1.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[1997,5,1]],"date-time":"1997-05-01T00:00:00Z","timestamp":862444800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":6794,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[1997,5]]},"DOI":"10.1038\/ki.1997.211","type":"journal-article","created":{"date-parts":[[2007,5,8]],"date-time":"2007-05-08T16:02:56Z","timestamp":1178640176000},"page":"1535-1539","source":"Crossref","is-referenced-by-count":18,"title":["Effects of sex hormones on fluid and solute transport in Madin-Darby canine kidney cells"],"prefix":"10.1016","volume":"51","author":[{"given":"Saeed","family":"Sandhu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon R.","family":"Silbiger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel","family":"Neugarten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/ki.1997.211_bb0010","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/S0272-6386(89)80068-X","article-title":"Is gender a determinant for evolution of renal failure? A study in autosomal dominant polycystic kidney disease","volume":"14","author":"Gretz","year":"1989","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/ki.1997.211_bb0015","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1038\/ki.1992.195","article-title":"Factors affecting the progression of renal disease in autosomal-dominant polycystic kidney disease","volume":"41","author":"Gabow","year":"1992","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1997.211_bb0020","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1681\/ASN.V5122037","article-title":"Dietary protein restriction, blood pressure control, and the progression of polycystic kidney disease","volume":"5","author":"Klahr","year":"1995","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.1997.211_bb0025","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1038\/ki.1993.79","article-title":"Autosomal-dominant polycystic kidney disease in the rat","volume":"43","author":"Cowley","year":"1993","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1997.211_bb0030","first-page":"621","article-title":"Effect of gonadal hormones on progression of inherited polycystic kidney disease in HAN-SPRD rats","volume":"5","author":"Cowley","year":"1994","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.1997.211_bb0035","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1038\/ki.1996.425","article-title":"The effects of sex hormones on mesangial cell proliferation and collagen synthe sis","volume":"50","author":"Kwan","year":"1996","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1997.211_bb0040","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0272-6386(95)90168-X","article-title":"Effects of sex hormones on mesangial cells","volume":"26","author":"Neugarten","year":"1995","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/ki.1997.211_bb0045","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/0272-6386(95)90119-1","article-title":"The impact of gender on the progression of chronic renal disease","volume":"25","author":"Silbiger","year":"1995","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/ki.1997.211_bb0050","doi-asserted-by":"crossref","first-page":"2629","DOI":"10.1096\/fasebj.3.14.2480260","article-title":"Renal epithelial fluid secretion and cyst growth: The role of cyclic AMP","volume":"3","author":"Mangoo-Karim","year":"1989","journal-title":"FASEB J"},{"key":"10.1038\/ki.1997.211_bb0055","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1038\/ki.1990.330","article-title":"Renal structure and hypertension in autosomal dominant polycystic kidney disease","volume":"38","author":"Gabow","year":"1990","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1997.211_bb0060","doi-asserted-by":"crossref","first-page":"6007","DOI":"10.1073\/pnas.86.15.6007","article-title":"Renal epithelial cyst formation and enlargement in vitro: Dependence on cAMP","volume":"86","author":"Mangoo-Karim","year":"1989","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/ki.1997.211_bb0065","first-page":"F381","article-title":"Anion secretion drives fluid secretion by monolayers of cultured human polycystic cells","volume":"269","author":"Mangoo-Karim","year":"1995","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1997.211_bb0070","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/0272-6386(95)90111-6","article-title":"Cyst fluid from a murine model of polycystic kidney disease stimulates fluid secretion, cyclic adenosine monophosphate accumulation, and cell proliferation by Madin-Darby canine kidney cells in vitro","volume":"25","author":"Yamaguchi","year":"1995","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/ki.1997.211_bb0075","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1038\/ki.1994.179","article-title":"Coupling of cell volume and membrane potential changes to fluid secretion in a model of renal cysts","volume":"45","author":"Sullivan","year":"1994","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1997.211_bb0080","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1038\/ki.1995.99","article-title":"Solute and fluid secretion mechanisms in ADPKD cells","volume":"47","author":"Sullivan","year":"1995","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1997.211_bb0085","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0167-4889(93)90186-S","article-title":"Regulation of white adipocyte guanine nucleotide binding proteins Gs\u03b1 and Gi\u03b11\u20132 hy testosterone in vivo: Influence of regional fat distribution","volume":"1176","author":"Dieudonne","year":"1993","journal-title":"Biochim Biophys Acta"},{"key":"10.1038\/ki.1997.211_bb0090","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1111\/j.1471-4159.1990.tb03131.x","article-title":"Pre-treatment of mouse striated neurons in primary culture with 17\u03b2-estradiol enhances the pertussis toxin-catalyzed ADP-ribosylation of G\u03b1o,i protein subunits","volume":"55","author":"Maus","year":"1990","journal-title":"J Neuochem"},{"key":"10.1038\/ki.1997.211_bb0095","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1210\/endo-126-1-241","article-title":"Evidence that testosterone modulates in vivo the adenylate cyclase activity in fat cells","volume":"126","author":"Pecquery","year":"1990","journal-title":"Endocrinology"},{"key":"10.1038\/ki.1997.211_bb0100","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1111\/j.1600-0773.1992.tb00502.x","article-title":"Effects of androgen treatment on adenylate cyclase system in rat hepatic membranes","volume":"70","author":"Shima","year":"1992","journal-title":"Pharmacol Toxicol"},{"key":"10.1038\/ki.1997.211_bb0105","doi-asserted-by":"crossref","first-page":"C909","DOI":"10.1152\/ajpcell.1994.267.4.C909","article-title":"Female sex hormones inhibit volume regulation in rat brain astrocyte culture","volume":"267","author":"Frase","year":"1994","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1997.211_bb0110","first-page":"347","article-title":"Effects of oestradiol, testosterone and medroxyprogesterone on subcellular fraction marker enzyme activities from rat liver and brain","volume":"80B","author":"Garcia","year":"1985","journal-title":"Comp Biochem Physiol"},{"key":"10.1038\/ki.1997.211_bb0115","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0304-3940(87)90568-4","article-title":"Androgens stimulate preoptic area Na+,K+-ATPase activity in male rats","volume":"78","author":"Guerra","year":"1987","journal-title":"Neurosci Lett"},{"key":"10.1038\/ki.1997.211_bb0120","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1681\/ASN.V22219","article-title":"Arginine vasopressin stimulates net fluid secretion in a polarized subcul ture of cyst-forming MDCK cells","volume":"2","author":"Grant","year":"1991","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.1997.211_bb0125","first-page":"8517","article-title":"Estrogen action via the cAMP signaling pathway: Stimulation of adenylate cyclase and cAMP-regulated gene transcription","volume":"91","author":"Aronica","year":"1994","journal-title":"Cell Biol"},{"key":"10.1038\/ki.1997.211_bb0130","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1038\/ki.1989.288","article-title":"In vitro modulation of tubular cyst regression in murine polycystic kidney disease","volume":"36","author":"Avner","year":"1989","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1997.211_bb0135","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1002\/jcp.1041230114","article-title":"The effect of ionophores and related agents on the induction of doming in a rat mammary epithelial cell line","volume":"123","author":"Paterson","year":"1985","journal-title":"J Cell Physiol"},{"key":"10.1038\/ki.1997.211_bb0140","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/S0272-6386(12)80591-9","article-title":"Time-related increase in hematocrit on chronic hemodialysis: Uncertain role of renal cysts","volume":"15","author":"Glicklich","year":"1990","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/ki.1997.211_bb0145","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/0090-4295(85)90038-X","article-title":"Uremic acquired cystic disease of the kidney","volume":"26","author":"Ishikawa","year":"1985","journal-title":"Urology"},{"key":"10.1038\/ki.1997.211_bb0150","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1681\/ASN.V17980","article-title":"A hereditary model of slowly progressive polycystic kidney disease in the mouse","volume":"1","author":"Takahashi","year":"1991","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.1997.211_bb0155","first-page":"231","article-title":"Autosomal recessive polycystic kidney disease in a murine model. A gross and microscopic description","volume":"59","author":"Gattone","year":"1988","journal-title":"Lab Invest"},{"key":"10.1038\/ki.1997.211_bb0160","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1681\/ASN.V34984","article-title":"Cyst fluid from human autosomal dominant polycystic kidneys promotes cyst formation and expansion by renal epithelial cells in vitro","volume":"3","author":"Ye","year":"1992","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.1997.211_bb0165","first-page":"F420","article-title":"Reversed polarity of Na+-K+-ATPase: Mislocation to apical plasma membranes in polycystic disease epithelia","volume":"260","author":"Wilson","year":"1991","journal-title":"Am J Physiol"},{"key":"10.1038\/ki.1997.211_bb0170","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1172\/JCI117638","article-title":"In vitro fluid secretion by epithelium from polycystic kidneys","volume":"95","author":"Grantham","year":"1995","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1997.211_bb0175","doi-asserted-by":"crossref","first-page":"11901","DOI":"10.1016\/S0021-9258(18)33651-2","article-title":"Stimulation by forskolin of intact S49 lymphoma cells involves the nucleotide regulatory protein of adenylate cyclase","volume":"257","author":"Darfler","year":"1982","journal-title":"Biol Chem"},{"key":"10.1038\/ki.1997.211_bb0180","doi-asserted-by":"crossref","first-page":"3363","DOI":"10.1073\/pnas.78.6.3363","article-title":"Forskolin: Unique diterpene activator of adenylate cyclase in membranes and in intact cells","volume":"78","author":"Seamon","year":"1981","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815600515?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815600515?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,30]],"date-time":"2021-10-30T00:06:45Z","timestamp":1635552405000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815600515"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,5]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1997,5]]}},"alternative-id":["S0085253815600515"],"URL":"https:\/\/doi.org\/10.1038\/ki.1997.211","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[1997,5]]}}}