{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:41:51Z","timestamp":1790743311710,"version":"4.1.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[1997,1,1]],"date-time":"1997-01-01T00:00:00Z","timestamp":852076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":6914,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[1997,1]]},"DOI":"10.1038\/ki.1997.41","type":"journal-article","created":{"date-parts":[[2007,5,8]],"date-time":"2007-05-08T15:15:29Z","timestamp":1178637329000},"page":"328-336","source":"Crossref","is-referenced-by-count":373,"title":["Depressed expression of calcium receptor in parathyroid gland tissue of patients with hyperparathyroidism"],"prefix":"10.1016","volume":"51","author":[{"given":"Jean","family":"Gogusev","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Duchambon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Hory","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Giovannini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yann","family":"Goureau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emile","family":"Sarfati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tilman B.","family":"Dr\u00fceke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/ki.1997.41_bb0010","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1097\/00041552-199407000-00003","article-title":"New aspects in the control of parathyroid hormone secretion","volume":"3","author":"Silver","year":"1994","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"10.1038\/ki.1997.41_bb0015","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/ki.1995.292","article-title":"The pathogenesis of parathyroid gland hyperplasia in chronic renal failure","volume":"48","author":"Dr\u00fceke","year":"1995","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1997.41_bb0020","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1172\/JCI116720","article-title":"Decreased 1,25-dihydroxyvitamin D3 receptor density is associated with a more severe form of parathyroid hyperplasia in chronic uremic patients","volume":"92","author":"Fukuda","year":"1993","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1997.41_bb0025","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1056\/NEJM198706183162504","article-title":"Reduced binding of 3H-1,25 dihydroxyvitamin D3 in the parathyroid glands of patients with renal failure","volume":"316","author":"Korkor","year":"1987","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1997.41_bb0030","first-page":"1703","article-title":"Cloning and characterization of an extracellular Ca2+-sensing receptor from parathyroid and kidney: New insights into the physiology and pathophysiology of calcium metabolism","volume":"9","author":"Brown","year":"1994","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.1997.41_bb0035","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1006\/excr.1994.1153","article-title":"A protein involved in calcium sensing of the human parathyroid and placental cytotrophoblast cell belongs to the LDL-receptor protein superfamily","volume":"212","author":"Lundgren","year":"1994","journal-title":"Exp Cell Res"},{"key":"10.1038\/ki.1997.41_bb0040","doi-asserted-by":"crossref","first-page":"2999","DOI":"10.1210\/endo-122-6-2999","article-title":"Hyperparathyroidism is associated with reduced expression of a parathyroid calcium receptor mechanism defined by monoclonal antiparathyroid antibodies","volume":"122","author":"Juhlin","year":"1988","journal-title":"Endocrinology"},{"key":"10.1038\/ki.1997.41_bb0045","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0143-4179(89)90081-4","article-title":"Simultaneous use of digoxigenin and radiolabeled oligodeoxyribonucleotide probes for hybridization histochemistry","volume":"13","author":"Young","year":"1989","journal-title":"Neuropeptides"},{"key":"10.1038\/ki.1997.41_bb0050","doi-asserted-by":"crossref","first-page":"5202","DOI":"10.1210\/endo.136.11.7588259","article-title":"Calcitonin-secreting cells of the thyroid express extracellular calcium receptor gene","volume":"136","author":"Garrett","year":"1995","journal-title":"Endocrinology"},{"key":"10.1038\/ki.1997.41_bb0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0165-0270(88)90125-2","article-title":"Quantitative immunochemis-try using an image analyzer. I. Hardware evaluation, image processing, and data analysis","volume":"26","author":"Mize","year":"1988","journal-title":"J Neurosci Meth"},{"key":"10.1038\/ki.1997.41_bb0060","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1016\/0092-8674(93)90617-Y","article-title":"Mutations in the human Ca2+ sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism","volume":"75","author":"Pollak","year":"1993","journal-title":"Cell"},{"key":"10.1038\/ki.1997.41_bb0065","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1038\/ng1194-303","article-title":"Autosomal dominant hypocalcemia caused by a Ca2+-sensing receptor gene mutation","volume":"8","author":"Pollak","year":"1994","journal-title":"Nature Genet"},{"key":"10.1038\/ki.1997.41_bb0070","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/ng1295-389","article-title":"A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism","volume":"11","author":"Ho","year":"1995","journal-title":"Nature Genet"},{"key":"10.1038\/ki.1997.41_bb0075","first-page":"3377","article-title":"Genetic abnormalities in sporadic parathyroid adenomas: Loss of heterozygosity for chromosome 3q markers flanking the calcium receptor locus","volume":"80","author":"Thompson","year":"1995","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1038\/ki.1997.41_bb0080","first-page":"3107","article-title":"The extracellular calcium sensing receptor gene in human parathyroid tumors","volume":"80","author":"Hosokawa","year":"1995","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1038\/ki.1997.41_bb0085","doi-asserted-by":"crossref","first-page":"12919","DOI":"10.1074\/jbc.270.21.12919","article-title":"Molecular cloning and functional expression of human parathyroid calcium receptor cDNAs","volume":"270","author":"Garrett","year":"1995","journal-title":"J Biol Chem"},{"key":"10.1038\/ki.1997.41_bb0090","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1210\/jcem-54-1-172","article-title":"Abnormal regulation of parathyroid hormone release by calcium in secondary hyperparathyroidism due to renal chronic renal failure","volume":"54","author":"Brown","year":"1982","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1038\/ki.1997.41_bb0095","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1038\/ki.1993.111","article-title":"Parathyroid gland function in renal failure","volume":"43","author":"Felsenfeld","year":"1993","journal-title":"Kidney Int"},{"key":"10.1038\/ki.1997.41_bb0100","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1111\/j.1365-2362.1994.tb01106.x","article-title":"Inter-relations between the calcium set points of Parfitt and Brown in primary hyperparathyroidism: A sequential citrate and calcium clamp","volume":"24","author":"Schwarz","year":"1994","journal-title":"Eur J Clin Invest"},{"key":"10.1038\/ki.1997.41_bb0105","first-page":"1489","article-title":"Direct in vivo comparison of calcium-regulated parathyroid hormone secretion in normal volunteers and patients with secondary hyperparathyrodism","volume":"76","author":"Ramirez","year":"1993","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1038\/ki.1997.41_bb0110","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1681\/ASN.V651371","article-title":"Differences in the dynamics of parathyroid hormone secretion in hemodialysis patients with marked secondary hyperparathyroidism","volume":"6","author":"Felsenfeld","year":"1995","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.1997.41_bb0115","first-page":"964","article-title":"Non-suppressible parathyroid hormone (PTH) secretion is related to parathyroid gland size in uremic secondary hyperparathyroidism","volume":"6","author":"Indridason","year":"1995","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.1997.41_bb0120","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1007\/BF02935679","article-title":"Parathyroid gland calcium receptor mRNA levels are unaffected by chronic renal insufficiency or low dietary calcium in rats","volume":"3","author":"Rogers","year":"1995","journal-title":"Endocrine"},{"key":"10.1038\/ki.1997.41_bb0125","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1210\/endo.136.4.7895652","article-title":"The roles of calcium and 1,25-dihydroxyvitamin D3 in the regulation of vitamin D receptor expression by rat parathyroid glands","volume":"136","author":"Brown","year":"1995","journal-title":"Endocrinology"},{"key":"10.1038\/ki.1997.41_bb0130","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1111\/j.1365-2362.1991.tb01404.x","article-title":"No decrease of l,25(OH)2D3 receptors and duodenal calbindin-D9k in uraemic rats","volume":"321","author":"Szabo","year":"1991","journal-title":"Eur J Clin Invest"},{"key":"10.1038\/ki.1997.41_bb0135","first-page":"931","article-title":"Expression of vitamin D (VDR) and Ca-sensing receptor in normal and pathologic human parathyroid tissue","volume":"10","author":"Gogusev","year":"1995","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.1997.41_bb0140","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1172\/JCI117890","article-title":"Monoclonality of parathyroid tumors in chronic renal failure and in primary parathyroid hyperplasia","volume":"95","author":"Arnold","year":"1995","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1997.41_bb0145","first-page":"92","article-title":"Hypercalcemic hyperparathyroidism following renal transplantation: Differential diagnosis, management and implications for cell population control in the parathyroid gland","volume":"8","author":"Parfitt","year":"1982","journal-title":"Miner Electrol Metab"},{"key":"10.1038\/ki.1997.41_bb0150","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1172\/JCI118224","article-title":"Parathyroid cell proliferation in normal and chronic renal failure rats. The effects of calcium, phosphate, and vitamin D","volume":"96","author":"Naveh-Many","year":"1995","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1997.41_bb0155","unstructured":"J. Gogusev, P. Duchambon, C. Stoermann-Chopard, M. Giovannini, E. Sarfati, T.B. Dr\u00fceke: De novo expression of transforming growth factor-\u03b1 in parathyroid gland tissue of patients with primary or secondary uraemic hyperparathyroidism. Nephrol Dial Transplant (in press)"},{"key":"10.1038\/ki.1997.41_bb0160","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1056\/NEJM198803173181102","article-title":"Monoclonality and abnormal parathyroid hormone genes in parathyroid adenomas","volume":"318","author":"Arnold","year":"1988","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.1997.41_bb0165","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.1172\/JCI114114","article-title":"Molecular cloning and chromosome mapping of DNA rearranged with the parathyroid hormone gene in parathyroid adenoma","volume":"83","author":"Arnold","year":"1989","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.1997.41_bb0170","first-page":"3105","article-title":"Molecular overtones of primary hyperparathyroidism","volume":"80","author":"El-Deiry","year":"1995","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1038\/ki.1997.41_bb0175","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1038\/nm1295-1309","article-title":"Vitamin D receptor genotypes in primary hyperparathyroidism","volume":"1","author":"Carling","year":"1995","journal-title":"Nature Med"},{"key":"10.1038\/ki.1997.41_bb0180","first-page":"1598","article-title":"Reduced immunostaining for the extracellular Ca2+-sensing receptor in primary and uremic secondary hyperparathyroidism","volume":"81","author":"Kifor","year":"1996","journal-title":"J Clin Endocrinol Metab"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S008525381559875X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S008525381559875X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T23:57:41Z","timestamp":1635551861000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S008525381559875X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,1]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1997,1]]}},"alternative-id":["S008525381559875X"],"URL":"https:\/\/doi.org\/10.1038\/ki.1997.41","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[1997,1]]}}}