{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T15:27:16Z","timestamp":1791214036120,"version":"4.1.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":2107,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2010,3]]},"DOI":"10.1038\/ki.2009.435","type":"journal-article","created":{"date-parts":[[2009,12,16]],"date-time":"2009-12-16T08:39:22Z","timestamp":1260952762000},"page":"443-449","source":"Crossref","is-referenced-by-count":140,"title":["Genotype\u2013phenotype correlation in primary hyperoxaluria type 1: the p.Gly170Arg AGXT mutation is associated with a better outcome"],"prefix":"10.1016","volume":"77","author":[{"given":"J\u00e9r\u00f4me","family":"Harambat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Fargue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Acquaviva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-France","family":"Gagnadoux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7oise","family":"Janssen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aur\u00e9lia","family":"Liutkus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chebl","family":"Mourani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Alice","family":"Macher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Abramowicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Legendre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Durrbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Tsimaratos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hubert","family":"Nivet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Girardin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne-Marie","family":"Schott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Odile","family":"Rolland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Cochat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/ki.2009.435_bb0010","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/0014-5793(86)80563-4","article-title":"Peroxisomal alanine: glyoxylate amino transferase deficiency in primary hyperoxaluria type 1","volume":"201","author":"Danpure","year":"1986","journal-title":"FEBS Lett"},{"issue":"Suppl 8","key":"10.1038\/ki.2009.435_bb0015","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1093\/ndt\/10.supp8.3","article-title":"on behalf of the Soci\u00e9t\u00e9 de N\u00e9phrologie and the Soci\u00e9t\u00e9 de N\u00e9phrologie P\u00e9diatrique. Epidemiology of primary hyperoxaluria type 1","volume":"10","author":"Cochat","year":"1995","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2009.435_bb0020","doi-asserted-by":"crossref","first-page":"2224","DOI":"10.1093\/ndt\/10.12.2224","article-title":"Changing pattern of primary hyperoxaluria in Switzerland","volume":"10","author":"Kopp","year":"1995","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2009.435_bb0025","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1093\/ndt\/18.2.273","article-title":"Primary hyperoxaluria type 1 in The Netherlands: prevalence and outcome","volume":"18","author":"van Woerden","year":"2003","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2009.435_bb0030","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1007\/s00467-006-0124-4","article-title":"Primary hyperoxaluria type 1: still challenging!","volume":"21","author":"Cochat","year":"2006","journal-title":"Pediatr Nephrol"},{"key":"10.1038\/ki.2009.435_bb0035","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1038\/ki.2009.32","article-title":"The primary hyperoxalurias","volume":"75","author":"Hoppe","year":"2009","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2009.435_bb0040","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1007\/BF00711363","article-title":"Primary hyperoxaluria type 1: genotypic and phenotypic heterogeneity","volume":"17","author":"Danpure","year":"1994","journal-title":"J Inherit Metab Dis"},{"key":"10.1038\/ki.2009.435_bb0045","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1159\/000085407","article-title":"The primary hyperoxalurias: an algorithm for diagnosis","volume":"25","author":"Milliner","year":"2005","journal-title":"Am J Nephrol"},{"key":"10.1038\/ki.2009.435_bb0050","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1007\/s00240-005-0494-2","article-title":"An overview of the role of genotyping in the diagnosis of the primary hyperoxalurias","volume":"33","author":"Rumsby","year":"2005","journal-title":"Urol Res"},{"key":"10.1038\/ki.2009.435_bb0055","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1159\/000086360","article-title":"International registry for primary hyperoxaluria","volume":"25","author":"Lieske","year":"2005","journal-title":"Am J Nephrol"},{"key":"10.1038\/ki.2009.435_bb0060","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1007\/s00467-003-1234-x","article-title":"A United States survey on diagnosis, treatment, and outcome of primary hyperoxaluria","volume":"18","author":"Hoppe","year":"2003","journal-title":"Pediatr Nephrol"},{"key":"10.1038\/ki.2009.435_bb0065","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1038\/sj.ki.5001758","article-title":"Presentation and role of transplantation in adult patients with type 1 primary hyperoxaluria and the I244T AGXT mutation: single-center experience","volume":"70","author":"Lorenzo","year":"2006","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2009.435_bb0070","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1016\/S0140-6736(89)92423-9","article-title":"Liver transplantation in primary hyperoxaluria type 1","volume":"1","author":"Cochat","year":"1989","journal-title":"Lancet"},{"key":"10.1038\/ki.2009.435_bb0075","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1159\/000080261","article-title":"Clinical value of crystalluria and quantitative morphoconstitutional analysis of urinary calculi","volume":"98","author":"Daudon","year":"2004","journal-title":"Nephron Physiol"},{"key":"10.1038\/ki.2009.435_bb0080","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1056\/NEJMc0800990","article-title":"Peculiar morphology of stones in primary hyperoxaluria","volume":"359","author":"Daudon","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.2009.435_bb0085","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1016\/S0022-3476(99)70095-8","article-title":"Primary hyperoxaluria in infants: medical, ethical, and economic issues","volume":"135","author":"Cochat","year":"1999","journal-title":"J Pediatr"},{"key":"10.1038\/ki.2009.435_bb0090","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1097\/01.TP.0000084203.76110.AC","article-title":"One hundred percent patient and kidney allograft survival with simultaneous liver and kidney transplantation in infants with primary hyperoxaluria: a single-center experience","volume":"76","author":"Millan","year":"2003","journal-title":"Transplantation"},{"key":"10.1038\/ki.2009.435_bb0095","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/S0272-6386(12)80833-X","article-title":"Oxalate balance studies in patients on hemodialysis for type I primary hyperoxaluria","volume":"19","author":"Marangella","year":"1992","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/ki.2009.435_bb0100","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1007\/s004670050145","article-title":"Oxalate elimination via hemodialysis or peritoneal dialysis in children with chronic renal failure","volume":"10","author":"Hoppe","year":"1996","journal-title":"Pediatr Nephrol"},{"key":"10.1038\/ki.2009.435_bb0105","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1007\/BF01957682","article-title":"Primary hyperoxaluria type I","volume":"149","author":"Latta","year":"1990","journal-title":"Eur J Pediatr"},{"key":"10.1038\/ki.2009.435_bb0110","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1056\/NEJM199412083312304","article-title":"Results of long-term treatment with orthophosphate and pyridoxine in patients with primary hyperoxaluria","volume":"331","author":"Milliner","year":"1994","journal-title":"N Engl J Med"},{"issue":"Suppl 8","key":"10.1038\/ki.2009.435_bb0115","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1093\/ndt\/10.supp8.14","article-title":"Efficacy of oral citrate administration in primary hyperoxaluria","volume":"10","author":"Leumann","year":"1995","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2009.435_bb0120","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1038\/ki.2009.237","article-title":"Renal outcome of children with primary hyperoxaluria type 1 on conservative treatment","volume":"76","author":"Fargue","year":"2009","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2009.435_bb0125","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1111\/j.1523-1755.2005.00267.x","article-title":"Pyridoxine effect in type I primary hyperoxaluria is associated with the most common mutant allele","volume":"67","author":"Monico","year":"2005","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2009.435_bb0130","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1111\/j.1523-1755.2004.00796.x","article-title":"Clinical implications of mutation analysis in primary hyperoxaluria type 1","volume":"66","author":"van Woerden","year":"2004","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2009.435_bb0135","doi-asserted-by":"crossref","first-page":"8349","DOI":"10.1074\/jbc.M808965200","article-title":"Molecular insight into the synergism between the minor allele of human liver peroxisomal alanine: glyoxylate aminotransferase and the F152I mutation","volume":"284","author":"Cellini","year":"2009","journal-title":"J Biol Chem"},{"key":"10.1038\/ki.2009.435_bb0140","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s00467-005-1813-0","article-title":"Primary hyperoxaluria type 1: is genotyping clinically helpful?","volume":"20","author":"Leumann","year":"2005","journal-title":"Pediatr Nephrol"},{"key":"10.1038\/ki.2009.435_bb0145","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1038\/sj.ki.5001797","article-title":"Is there a genotype-phenotype correlation in primary hyperoxaluria type 1?","volume":"70","author":"Beck","year":"2006","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2009.435_bb0150","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1093\/ndt\/5.5.332","article-title":"Kidney transplantation in primary oxalosis: data from the EDTA Registry","volume":"5","author":"Broyer","year":"1990","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2009.435_bb0155","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1097\/00007890-200209150-00020","article-title":"Renal allograft survival in patients with oxalosis","volume":"74","author":"Cibrik","year":"2002","journal-title":"Transplantation"},{"key":"10.1038\/ki.2009.435_bb0160","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/S0031-3955(16)36251-4","article-title":"The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children, and adolescents","volume":"34","author":"Schwartz","year":"1987","journal-title":"Pediatr Clin North Am"},{"key":"10.1038\/ki.2009.435_bb0165","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1159\/000180580","article-title":"Prediction of creatinine clearance from serum creatinine","volume":"16","author":"Cockcroft","year":"1976","journal-title":"Nephron"},{"key":"10.1038\/ki.2009.435_bb0170","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1542\/peds.111.6.1416","volume":"111","author":"Hogg","year":"2003","journal-title":"Pediatrics"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815542658?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815542658?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T11:25:04Z","timestamp":1558697104000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815542658"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3]]},"references-count":33,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,3]]}},"alternative-id":["S0085253815542658"],"URL":"https:\/\/doi.org\/10.1038\/ki.2009.435","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2010,3]]}}}