{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T19:19:35Z","timestamp":1790882375406,"version":"4.1.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":1742,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2011,3]]},"DOI":"10.1038\/ki.2010.484","type":"journal-article","created":{"date-parts":[[2010,12,15]],"date-time":"2010-12-15T08:59:47Z","timestamp":1292403587000},"page":"663-670","source":"Crossref","is-referenced-by-count":154,"title":["Progressive podocyte injury and globotriaosylceramide (GL-3) accumulation in young patients with Fabry disease"],"prefix":"10.1016","volume":"79","author":[{"given":"Behzad","family":"Najafian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Einar","family":"Svarstad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leif","family":"Bostad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Claire","family":"Gubler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilla","family":"T\u00f8ndel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chester","family":"Whitley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Mauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/ki.2010.484_bb0010","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1136\/bmj.1.5082.1266","article-title":"The renal lesion in angiokeratoma corporis diffusum","volume":"1","author":"Colley","year":"1958","journal-title":"Br Med J"},{"key":"10.1038\/ki.2010.484_bb0015","doi-asserted-by":"crossref","first-page":"S134","DOI":"10.1097\/01.ASN.0000016684.07368.75","article-title":"Renal pathology in fabry disease","volume":"13","author":"Alroy","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2010.484_bb0020","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1136\/jmg.38.11.750","article-title":"Anderson-Fabry disease: clinical manifestations and impact of disease in a cohort of 98 hemizygous males","volume":"38","author":"MacDermot","year":"2001","journal-title":"J Med Genet"},{"key":"10.1038\/ki.2010.484_bb0025","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1136\/jmg.38.11.769","article-title":"Anderson-Fabry disease: clinical manifestations and impact of disease in a cohort of 60 obligate carrier females","volume":"38","author":"MacDermot","year":"2001","journal-title":"J Med Genet"},{"key":"10.1038\/ki.2010.484_bb0030","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.ymgme.2007.09.013","article-title":"Females with Fabry disease frequently have major organ involvement: lessons from the Fabry Registry","volume":"93","author":"Wilcox","year":"2008","journal-title":"Mol Genet Metab"},{"key":"10.1038\/ki.2010.484_bb0035","doi-asserted-by":"crossref","first-page":"2102","DOI":"10.1093\/ndt\/gfp031","article-title":"Fabry disease: progression of nephropathy, and prevalence of cardiac and cerebrovascular events before enzyme replacement therapy","volume":"24","author":"Schiffmann","year":"2009","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2010.484_bb0040","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/S0272-6386(83)80047-X","article-title":"Early renal failure in Fabry\u2019s disease","volume":"2","author":"Sheth","year":"1983","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/ki.2010.484_bb0045","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1053\/j.ajkd.2007.12.032","article-title":"Renal biopsy findings in children and adolescents with Fabry disease and minimal albuminuria","volume":"51","author":"T\u00f8ndel","year":"2008","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/ki.2010.484_bb0050","doi-asserted-by":"crossref","first-page":"2168","DOI":"10.1093\/ndt\/gfp528","article-title":"Scoring system for renal pathology in Fabry disease: report of the International Study Group of Fabry Nephropathy (ISGFN)","volume":"25","author":"Fogo","year":"2010","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2010.484_bb0055","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1097\/00005792-200203000-00003","article-title":"Natural history of Fabry renal disease: influence of alpha-galactosidase A activity and genetic mutations on clinical course","volume":"81","author":"Branton","year":"2002","journal-title":"Medicine (Baltimore)"},{"key":"10.1038\/ki.2010.484_bb0060","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1093\/ndt\/gfi152","article-title":"Long-term therapy with agalsidase alfa for Fabry disease: safety and effects on renal function in a home infusion setting","volume":"21","author":"Schiffmann","year":"2006","journal-title":"Nephrol Dial Transplant"},{"issue":"Suppl 92","key":"10.1038\/ki.2010.484_bb0065","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/j.1651-2227.2003.tb00214.x","article-title":"Effects of enzyme replacement therapy with agalsidase alfa on glomerular filtration rate in patients with Fabry disease: preliminary data","volume":"5","author":"Dehout","year":"2003","journal-title":"Acta Paediatr"},{"key":"10.1038\/ki.2010.484_bb0070","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1681\/ASN.2006111263","article-title":"Weekly enzyme replacement therapy may slow decline of renal function in patients with Fabry disease who are on long-term biweekly dosing","volume":"18","author":"Schiffmann","year":"2007","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2010.484_bb0075","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1681\/ASN.2008080870","article-title":"Agalsidase alfa and kidney dysfunction in Fabry disease","volume":"20","author":"West","year":"2009","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2010.484_bb0080","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/ki.1978.32","article-title":"Early renal changes in hemizygous and heterozygous patients with Fabry\u2019s disease","volume":"13","author":"Gubler","year":"1978","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2010.484_bb0085","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/BF01986897","article-title":"Ein beitrag zur kenntnis der purpura haemorrhagica nodularis (Purpura papulosa hemorrhagica Hebrae)","volume":"43","author":"Fabry","year":"1898","journal-title":"Arch Dermatol Syphilis"},{"key":"10.1038\/ki.2010.484_bb0090","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1111\/j.0954-6820.1947.tb06596.x","article-title":"Angiokeratoma corporis diffusum (universale) Fabry, as a sign of an unknown internal disease; two autopsy reports","volume":"128","author":"Pompen","year":"1947","journal-title":"Acta Med Scand"},{"key":"10.1038\/ki.2010.484_bb0095","first-page":"575","article-title":"Fabry\u2019s disease in children. Clinical and biological study of one family. Structure and ultrastructure of the kidney in a hemizygote and a heterozygote","volume":"24","author":"Desbois","year":"1977","journal-title":"Ann Pediatr (Paris)"},{"key":"10.1038\/ki.2010.484_bb0100","first-page":"7","article-title":"Fetal pathology in Fabry\u2019s disease and mucopolysaccharidosis type I","volume":"34","author":"Elleder","year":"1998","journal-title":"Cesk Patol"},{"key":"10.1038\/ki.2010.484_bb0105","first-page":"157","article-title":"Fabry\u2019s disease: enzymatic diagnosis of hemizygotes and heterozygotes. Alpha-galactosidase activities in plasma, serum, urine, and leukocytes","volume":"81","author":"Desnick","year":"1973","journal-title":"J Lab Clin Med"},{"key":"10.1038\/ki.2010.484_bb0110","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1447-0756.1985.tb00045.x","article-title":"Early prenatal diagnosis of inborn error of metabolism: a case report of a fetus affected with Fabry\u2019s disease","volume":"11","author":"Tsutsumi","year":"1985","journal-title":"Asia Oceania J Obstet Gynaecol"},{"key":"10.1038\/ki.2010.484_bb0115","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/j.1365-2818.1987.tb02837.x","article-title":"The efficiency of systematic sampling in stereology and its prediction","volume":"147","author":"Gundersen","year":"1987","journal-title":"J Microsc"},{"key":"10.1038\/ki.2010.484_bb0120","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1038\/sj.ki.5000410","article-title":"The podocyte\u2019s response to injury: role in proteinuria and glomerulosclerosis","volume":"69","author":"Shankland","year":"2006","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2010.484_bb0125","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1046\/j.1523-1755.1998.00044.x","article-title":"Progression of glomerular diseases: is the podocyte the culprit?","volume":"54","author":"Kriz","year":"1998","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2010.484_bb0130","doi-asserted-by":"crossref","first-page":"998","DOI":"10.2215\/CJN.04631007","article-title":"Albumin excretion rate in normal adolescents: relation to insulin resistance and cardiovascular risk factors and comparisons to type 1 diabetes mellitus patients","volume":"3","author":"Rademacher","year":"2008","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1038\/ki.2010.484_bb0135","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1007\/s00467-005-1829-5","article-title":"Widening of foot processes in normoalbuminuric adolescents with type 1 diabetes","volume":"20","author":"Torbj\u00f6rnsdotter","year":"2005","journal-title":"Pediatr Nephrol"},{"key":"10.1038\/ki.2010.484_bb0140","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1681\/ASN.2006080816","article-title":"Sustained, long-term renal stabilization after 54 months of agalsidase beta therapy in patients with Fabry disease","volume":"18","author":"Germain","year":"2007","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2010.484_bb0145","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1046\/j.1523-1755.2002.00675.x","article-title":"Globotriaosylceramide accumulation in the Fabry kidney is cleared from multiple cell types after enzyme replacement therapy","volume":"62","author":"Thurberg","year":"2002","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2010.484_bb0150","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1097\/GIM.0b013e3181981d82","article-title":"Evaluation of a low dose, after a standard therapeutic dose, of agalsidase beta during enzyme replacement therapy in patients with Fabry disease","volume":"11","author":"Lubanda","year":"2009","journal-title":"Genet Med"},{"key":"10.1038\/ki.2010.484_bb0155","doi-asserted-by":"crossref","DOI":"10.2215\/CJN.04340510","article-title":"Prognostic indicators of renal disease progression in adults with Fabry disease: natural history data from the Fabry registry","author":"Wanner","year":"2010","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1038\/ki.2010.484_bb0160","doi-asserted-by":"crossref","first-page":"77","DOI":"10.7326\/0003-4819-146-2-200701160-00148","article-title":"Agalsidase-beta therapy for advanced Fabry disease: a randomized trial","volume":"146","author":"Banikazemi","year":"2007","journal-title":"Ann Intern Med"},{"key":"10.1038\/ki.2010.484_bb0165","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.2337\/db07-0019","article-title":"Podocyte detachment and reduced glomerular capillary endothelial fenestration in human type 1 diabetic nephropathy","volume":"56","author":"Toyoda","year":"2007","journal-title":"Diabetes"},{"key":"10.1038\/ki.2010.484_bb0170","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1681\/ASN.2008111190","article-title":"Decreased nitric oxide bioavailability in a mouse model of Fabry disease","volume":"20","author":"Shu","year":"2009","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2010.484_bb0175","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1097\/01.ASN.0000075554.31464.DA","article-title":"Glomerular structure in the normal human kidney: differences between living and cadaver donors","volume":"14","author":"Caramori","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2010.484_bb0180","doi-asserted-by":"crossref","first-page":"506","DOI":"10.2337\/diabetes.51.2.506","article-title":"Cellular basis of diabetic nephropathy: 1. Study design and renal structural-functional relationships in patients with long-standing type 1 diabetes","volume":"51","author":"Caramori","year":"2002","journal-title":"Diabetes"},{"key":"10.1038\/ki.2010.484_bb0185","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/S0022-3476(84)80478-3","article-title":"Assessment of proteinuria using random urine samples","volume":"104","author":"Houser","year":"1984","journal-title":"J Pediatr"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815548540?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815548540?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T21:28:28Z","timestamp":1712006908000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815548540"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3]]},"references-count":36,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,3]]}},"alternative-id":["S0085253815548540"],"URL":"https:\/\/doi.org\/10.1038\/ki.2010.484","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2011,3]]}}}