{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T04:05:56Z","timestamp":1791345956803,"version":"4.3.1"},"reference-count":50,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,7]],"date-time":"2015-12-07T00:00:00Z","timestamp":1449446400000},"content-version":"vor","delay-in-days":1497,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2011,11]]},"DOI":"10.1038\/ki.2011.256","type":"journal-article","created":{"date-parts":[[2011,8,17]],"date-time":"2011-08-17T12:46:56Z","timestamp":1313585216000},"page":"1055-1063","source":"Crossref","is-referenced-by-count":56,"title":["Non-muscle myosin IIA is required for the development of the zebrafish glomerulus"],"prefix":"10.1016","volume":"80","author":[{"given":"Tobias","family":"M\u00fcller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Rumpel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Hradetzky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Bollig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henny","family":"Wegner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antje","family":"Blumenthal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Greinacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karlhans","family":"Endlich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Endlich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/ki.2011.256_bb0010","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1242\/jcs.058297","article-title":"Cytoskeletal coherence requires myosin-IIA contractility","volume":"123","author":"Cai","year":"2010","journal-title":"J Cell Sci"},{"key":"10.1038\/ki.2011.256_bb0015","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/j.cub.2010.04.058","article-title":"Determinants of myosin II cortical localization during cytokinesis","volume":"20","author":"Uehara","year":"2010","journal-title":"Curr Biol"},{"key":"10.1038\/ki.2011.256_bb0020","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1038\/embor.2008.135","article-title":"Involvement of RhoA, ROCK I and myosin II in inverted orientation of epithelial polarity","volume":"9","author":"Yu","year":"2008","journal-title":"EMBO Rep"},{"key":"10.1038\/ki.2011.256_bb0025","doi-asserted-by":"crossref","first-page":"L29","DOI":"10.1016\/j.bpj.2010.02.028","article-title":"Myosin IIA dependent retrograde flow drives 3D cell migration","volume":"98","author":"Shih","year":"2010","journal-title":"Biophys J"},{"key":"10.1038\/ki.2011.256_bb0030","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1083\/jcb.201003057","article-title":"Myosin II directly binds and inhibits Dbl family guanine nucleotide exchange factors: a possible link to Rho family GTPases","volume":"190","author":"Lee","year":"2010","journal-title":"J Cell Biol"},{"key":"10.1038\/ki.2011.256_bb0035","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1242\/jcs.007112","article-title":"Nonmuscle myosin II moves in new directions","volume":"121","author":"Conti","year":"2008","journal-title":"J Cell Sci"},{"key":"10.1038\/ki.2011.256_bb0040","first-page":"239","article-title":"Myosins: tails (and heads) of functional diversity","volume":"20","author":"Krendel","year":"2005","journal-title":"Physiology (Bethesda)"},{"key":"10.1038\/ki.2011.256_bb0045","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1055\/s-0029-1220327","article-title":"MYH9-related platelet disorders","volume":"35","author":"Althaus","year":"2009","journal-title":"Semin Thromb Hemost"},{"key":"10.1038\/ki.2011.256_bb0050","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1097\/01.md.0000076006.64510.5c","article-title":"MYH9-related disease: May-Hegglin anomaly, Sebastian syndrome, Fechtner syndrome, and Epstein syndrome are not distinct entities but represent a variable expression of a single illness","volume":"82","author":"Seri","year":"2003","journal-title":"Medicine (Baltimore)"},{"key":"10.1038\/ki.2011.256_bb0055","doi-asserted-by":"crossref","first-page":"3447","DOI":"10.1182\/blood.V96.10.3447","article-title":"Autosomal-dominant giant platelet syndromes: a hint of the same genetic defect as in Fechtner syndrome owing to a similar genetic linkage to chromosome 22q11-13","volume":"96","author":"Toren","year":"2000","journal-title":"Blood"},{"key":"10.1038\/ki.2011.256_bb0060","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/0002-9343(72)90017-4","article-title":"Hereditary macrothrombocytopathia, nephritis and deafness","volume":"52","author":"Epstein","year":"1972","journal-title":"Am J Med"},{"key":"10.1038\/ki.2011.256_bb0065","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1007\/BF00856828","article-title":"Hereditary nephritis, platelet disorders and deafness-Epstein's syndrome","volume":"6","author":"Turi","year":"1992","journal-title":"Pediatr Nephrol"},{"key":"10.1038\/ki.2011.256_bb0070","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1136\/jcp.50.11.919","article-title":"Normal distribution of collagen IV in renal basement membranes in Epstein's syndrome","volume":"50","author":"Naito","year":"1997","journal-title":"J Clin Pathol"},{"key":"10.1038\/ki.2011.256_bb0075","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1080\/08860220903033708","article-title":"Epstein syndrome presenting as renal failure in young patients","volume":"31","author":"Yap","year":"2009","journal-title":"Ren Fail"},{"key":"10.1038\/ki.2011.256_bb0080","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1182\/blood.V65.2.397.397","article-title":"Fechtner syndrome\u2014a variant of Alport's syndrome with leukocyte inclusions and macrothrombocytopenia","volume":"65","author":"Peterson","year":"1985","journal-title":"Blood"},{"key":"10.1038\/ki.2011.256_bb0085","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/ki.2010.21","article-title":"Patients with Epstein-Fechtner syndromes owing to MYH9 R702 mutations develop progressive proteinuric renal disease","volume":"78","author":"Sekine","year":"2010","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2011.256_bb0090","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1038\/ki.2010.82","article-title":"Glomerular pathology in autosomal dominant MYH9 spectrum disorders: what are the clues telling us about disease mechanism?","volume":"78","author":"Kopp","year":"2010","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2011.256_bb0095","doi-asserted-by":"crossref","first-page":"41263","DOI":"10.1074\/jbc.C400352200","article-title":"Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain II-A in mice","volume":"279","author":"Conti","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1038\/ki.2011.256_bb0100","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/j.bbrc.2004.10.147","article-title":"Targeted disruption of mouse ortholog of the human MYH9 responsible for macrothrombocytopenia with different organ involvement: hematological, nephrological, and otological studies of heterozygous KO mice","volume":"325","author":"Matsushita","year":"2004","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1038\/ki.2011.256_bb0105","doi-asserted-by":"crossref","first-page":"4655","DOI":"10.1242\/dev.125.23.4655","article-title":"Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function","volume":"125","author":"Drummond","year":"1998","journal-title":"Development"},{"key":"10.1038\/ki.2011.256_bb0110","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.ydbio.2005.06.038","article-title":"Organization of the pronephric filtration apparatus in zebrafish requires nephrin, podocin and the FERM domain protein mosaic eyes","volume":"285","author":"Kramer-Zucker","year":"2005","journal-title":"Dev Biol"},{"key":"10.1038\/ki.2011.256_bb0115","doi-asserted-by":"crossref","first-page":"F1746","DOI":"10.1152\/ajprenal.00009.2007","article-title":"Rapid screening of glomerular slit diaphragm integrity in larval zebrafish","volume":"293","author":"Hentschel","year":"2007","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1038\/ki.2011.256_bb0120","doi-asserted-by":"crossref","first-page":"2883","DOI":"10.1242\/dev.031773","article-title":"A highly conserved retinoic acid responsive element controls wt1a expression in the zebrafish pronephros","volume":"136","author":"Bollig","year":"2009","journal-title":"Development"},{"key":"10.1038\/ki.2011.256_bb0125","doi-asserted-by":"crossref","first-page":"8579","DOI":"10.1073\/pnas.0811691106","article-title":"Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development","volume":"21","author":"Skouloudaki","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1038\/ki.2011.256_bb0130","doi-asserted-by":"crossref","first-page":"e12626","DOI":"10.1371\/journal.pone.0012626","article-title":"Cofilin-1 inactivation leads to proteinuria","volume":"9","author":"Ashworth","year":"2010","journal-title":"PLoS One"},{"key":"10.1038\/ki.2011.256_bb0135","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/B978-0-12-384892-5.00009-8","article-title":"Zebrafish kidney development","volume":"100","author":"Drummond","year":"2010","journal-title":"Methods Cell Biol"},{"key":"10.1038\/ki.2011.256_bb0140","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1097\/MNH.0b013e3283477797","article-title":"Zebrafish: a model system for the study of vertebrate renal development, function, and pathophysiology","volume":"20","author":"Ebarasi","year":"2011","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"10.1038\/ki.2011.256_bb0145","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.ydbio.2007.06.022","article-title":"The Wilms tumor genes wt1a and wt1b control different steps during formation of the zebrafish pronephros","volume":"309","author":"Perner","year":"2007","journal-title":"Dev Biol"},{"key":"10.1038\/ki.2011.256_bb0150","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.devcel.2009.08.011","article-title":"The molecular basis of vascular lumen formation in the developing mouse aorta","volume":"17","author":"Strilic","year":"2009","journal-title":"Dev Cell"},{"key":"10.1038\/ki.2011.256_bb0155","doi-asserted-by":"crossref","first-page":"3564","DOI":"10.1182\/blood-2005-07-2961","article-title":"The angiogenic function of nucleolin is mediated by vascular endothelial growth factor and nonmuscle myosin","volume":"107","author":"Huang","year":"2006","journal-title":"Blood"},{"key":"10.1038\/ki.2011.256_bb0160","doi-asserted-by":"crossref","first-page":"14645","DOI":"10.1073\/pnas.1004023107","article-title":"Nonmuscle myosin II isoform and domain specificity during early mouse development","volume":"107","author":"Wang","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1038\/ki.2011.256_bb0165","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.cub.2008.12.045","article-title":"Local cortical tension by myosin II guides 3D endothelial cell branching","volume":"19","author":"Fischer","year":"2009","journal-title":"Curr Biol"},{"key":"10.1038\/ki.2011.256_bb0170","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1681\/ASN.2007040471","article-title":"How do mesangial and endothelial cells form the glomerular tuft?","volume":"19","author":"Vaughan","year":"2008","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2011.256_bb0175","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/nature08994","article-title":"Myosin II contributes to cell-scale actin network treadmilling through network disassembly","volume":"465","author":"Wilson","year":"2010","journal-title":"Nature"},{"key":"10.1038\/ki.2011.256_bb0180","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1083\/jcb.140.4.947","article-title":"Vascular endothelial growth factor induces endothelial fenestrations in vitro","volume":"140","author":"Esser","year":"1998","journal-title":"J Cell Biol"},{"key":"10.1038\/ki.2011.256_bb0185","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1038\/sj.ki.5000277","article-title":"Conditionally immortalized human glomerular endothelial cells expressing fenestrations in response to VEGF","volume":"69","author":"Satchell","year":"2006","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2011.256_bb0190","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1172\/JCI17423","article-title":"Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases","volume":"111","author":"Eremina","year":"2003","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.2011.256_bb0195","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1053\/ajkd.2003.50028","article-title":"Genetics, clinical and pathological features of glomerulonephritis associated with mutations of nonmuscle myosin IIA (Fechtner syndrome)","volume":"41","author":"Ghiggeri","year":"2003","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/ki.2011.256_bb0200","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1172\/JCI107858","article-title":"The immunohistopathology of glomerular antigens. The glomerular basement membrane, collagen, and actomyosin antigens in normal and diseased kidneys","volume":"54","author":"Scheinman","year":"1974","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.2011.256_bb0205","doi-asserted-by":"crossref","first-page":"64","DOI":"10.4103\/0971-4065.42336","article-title":"Thickness of glomerular and tubular basement membranes in preclinical and clinical stages of diabetic nephropathy","volume":"18","author":"Tyagi","year":"2008","journal-title":"Indian J Nephrol"},{"key":"10.1038\/ki.2011.256_bb0210","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1080\/00313020902884485","article-title":"Glomerular basement membrane thickness in an Asian population using a novel image analysis software","volume":"41","author":"Teng","year":"2009","journal-title":"Pathology"},{"key":"10.1038\/ki.2011.256_bb0215","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1007\/s004670050700","article-title":"End-stage renal disease in two pediatric patients with Fechtner syndrome","volume":"13","author":"Moxey-Mims","year":"1999","journal-title":"Pediatr Nephrol"},{"key":"10.1038\/ki.2011.256_bb0220","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1681\/ASN.V13165","article-title":"Expression of the nonmuscle myosin heavy chain IIA in the human kidney and screening for MYH9 mutations in Epstein and Fechtner syndromes","volume":"13","author":"Arrondel","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2011.256_bb0225","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/j.1523-1755.2004.00712.x","article-title":"DDR1-deficient mice show localized subepithelial GBM thickening with focal loss of slit diaphragms and proteinuria","volume":"66","author":"Gross","year":"2004","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2011.256_bb0230","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1242\/jcs.046219","article-title":"The collagen receptor DDR1 regulates cell spreading and motility by associating with myosin IIA","volume":"122","author":"Huang","year":"2009","journal-title":"J Cell Sci"},{"key":"10.1038\/ki.2011.256_bb0235","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/labinvest.3700692","article-title":"Inner ear defects and hearing loss in mice lacking the collagen receptor DDR1","volume":"88","author":"Meyer zum Gottesberge","year":"2008","journal-title":"Lab Invest"},{"key":"10.1038\/ki.2011.256_bb0240","doi-asserted-by":"crossref","first-page":"3183","DOI":"10.1182\/blood-2007-03-080184","article-title":"Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion","volume":"110","author":"Leon","year":"2007","journal-title":"Blood"},{"key":"10.1038\/ki.2011.256_bb0245","series-title":"The Zebrafish Book","author":"Westerfield","year":"2000"},{"key":"10.1038\/ki.2011.256_bb0250","doi-asserted-by":"crossref","first-page":"313","DOI":"10.3109\/10520296009114754","article-title":"Embedding in epoxy resins for ultrathin sectioning in electron microscopy","volume":"35","author":"Richardson","year":"1960","journal-title":"Stain Technol"},{"key":"10.1038\/ki.2011.256_bb0255","first-page":"158","article-title":"A modified method for lead staining of thin sections","volume":"17","author":"Sato","year":"1968","journal-title":"J Electron Microsc (Tokyo)"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815549533?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815549533?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,6,25]],"date-time":"2022-06-25T15:38:53Z","timestamp":1656171533000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815549533"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11]]},"references-count":50,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["S0085253815549533"],"URL":"https:\/\/doi.org\/10.1038\/ki.2011.256","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2011,11]]}}}