{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T06:51:25Z","timestamp":1792133485876,"version":"4.4.0"},"reference-count":151,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"vor","delay-in-days":1461,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2012,10]]},"DOI":"10.1038\/ki.2012.176","type":"journal-article","created":{"date-parts":[[2012,5,23]],"date-time":"2012-05-23T09:44:28Z","timestamp":1337766268000},"page":"737-747","source":"Crossref","is-referenced-by-count":327,"title":["Update on fibroblast growth factor 23 in chronic kidney disease"],"prefix":"10.1016","volume":"82","author":[{"given":"Myles","family":"Wolf","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/ki.2012.176_bb0010","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1172\/JCI18399","article-title":"FGF-23 in fibrous dysplasia of bone and its relationship to renal phosphate wasting","volume":"112","author":"Riminucci","year":"2003","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.2012.176_bb0015","doi-asserted-by":"crossref","first-page":"E38","DOI":"10.1152\/ajpendo.00008.2006","article-title":"Pathogenic role of Fgf23 in Hyp mice","volume":"291","author":"Liu","year":"2006","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1038\/ki.2012.176_bb0020","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/j.bone.2009.08.008","article-title":"Patterns of FGF-23, DMP1, and MEPE expression in patients with chronic kidney disease","volume":"45","author":"Pereira","year":"2009","journal-title":"Bone"},{"key":"10.1038\/ki.2012.176_bb0025","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1038\/nature05315","article-title":"Klotho converts canonical FGF receptor into a specific receptor for FGF23","volume":"444","author":"Urakawa","year":"2006","journal-title":"Nature"},{"key":"10.1038\/ki.2012.176_bb0030","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.bbrc.2003.12.102","article-title":"FGF-23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa","volume":"314","author":"Shimada","year":"2004","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1038\/ki.2012.176_bb0035","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1359\/JBMR.0301264","article-title":"FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis","volume":"19","author":"Shimada","year":"2004","journal-title":"J Bone Miner Res"},{"key":"10.1038\/ki.2012.176_bb0040","first-page":"4003","article-title":"The parathyroid is a target organ for FGF23 in rats","volume":"117","author":"Ben-Dov","year":"2007","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.2012.176_bb0045","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1681\/ASN.2009121293","article-title":"Forging forward with 10 burning questions on FGF23 in kidney disease","volume":"21","author":"Wolf","year":"2010","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0050","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1038\/ki.2009.466","article-title":"FGF23-parathyroid interaction: implications in chronic kidney disease","volume":"77","author":"Komaba","year":"2010","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0055","doi-asserted-by":"crossref","first-page":"S20","DOI":"10.1038\/ki.2011.26","article-title":"Phosphate and Klotho","volume":"121","author":"Kuro","year":"2011","journal-title":"Kidney Int Suppl"},{"key":"10.1038\/ki.2012.176_bb0060","doi-asserted-by":"crossref","first-page":"3820","DOI":"10.1172\/JCI36479","article-title":"Endocrine functions of bone in mineral metabolism regulation","volume":"118","author":"Quarles","year":"2008","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.2012.176_bb0065","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1007\/s00467-010-1565-3","article-title":"FGF23 and the parathyroid glands","volume":"25","author":"Silver","year":"2010","journal-title":"Pediatr Nephrol"},{"key":"10.1038\/ki.2012.176_bb0070","doi-asserted-by":"crossref","first-page":"S24","DOI":"10.1038\/ki.2011.27","article-title":"Phosphate and FGF-23","volume":"121","author":"Juppner","year":"2011","journal-title":"Kidney Int Suppl"},{"key":"10.1038\/ki.2012.176_bb0075","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1038\/ki.2008.643","article-title":"Latest findings in phosphate homeostasis","volume":"75","author":"Prie","year":"2009","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0080","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1038\/nm0411-428","article-title":"The bone and beyond: \u2018Dem bones\u2019 are made for more than walking","volume":"17","author":"Quarles","year":"2011","journal-title":"Nat Med"},{"key":"10.1038\/ki.2012.176_bb0085","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1210\/jc.2004-1039","article-title":"Fibroblast growth factor-23 relationship to dietary phosphate and renal phosphate handling in healthy young men","volume":"90","author":"Ferrari","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1038\/ki.2012.176_bb0090","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1359\/jbmr.060507","article-title":"Regulation of C-terminal and intact FGF-23 by dietary phosphate in men and women","volume":"21","author":"Burnett","year":"2006","journal-title":"J Bone Miner Res"},{"key":"10.1038\/ki.2012.176_bb0095","doi-asserted-by":"crossref","first-page":"3144","DOI":"10.1210\/jc.2006-0021","article-title":"Dietary phosphorus regulates serum fibroblast growth factor-23 concentrations in healthy men","volume":"91","author":"Antoniucci","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1038\/ki.2012.176_bb0100","doi-asserted-by":"crossref","first-page":"2871","DOI":"10.2215\/CJN.02740311","article-title":"Fibroblast growth factor 23, cardiovascular disease risk factors, and phosphorus intake in the Health Professionals Follow-up Study","volume":"6","author":"Gutierrez","year":"2011","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0105","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1111\/j.1525-139X.2010.00750.x","article-title":"Dietary phosphorus restriction in advanced chronic kidney disease: merits, challenges, and emerging strategies","volume":"23","author":"Gutierrez","year":"2010","journal-title":"Semin Dial"},{"key":"10.1038\/ki.2012.176_bb0110","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.bone.2006.10.016","article-title":"Effects of gonadal steroid withdrawal on serum phosphate and FGF-23 levels in men","volume":"40","author":"Burnett-Bowie","year":"2007","journal-title":"Bone"},{"key":"10.1038\/ki.2012.176_bb0115","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s00774-007-0779-3","article-title":"Effect of acute changes of serum phosphate on fibroblast growth factor (FGF)23 levels in humans","volume":"25","author":"Ito","year":"2007","journal-title":"J Bone Miner Metab"},{"key":"10.1038\/ki.2012.176_bb0120","doi-asserted-by":"crossref","first-page":"F882","DOI":"10.1152\/ajprenal.00360.2010","article-title":"PTH increases FGF23 gene expression and mediates the high-FGF23 levels of experimental kidney failure: a bone parathyroid feedback loop","volume":"299","author":"Lavi-Moshayoff","year":"2010","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1038\/ki.2012.176_bb0125","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1681\/ASN.2005111185","article-title":"Fibroblast growth factor 23 is a counter-regulatory phosphaturic hormone for vitamin D","volume":"17","author":"Liu","year":"2006","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0130","doi-asserted-by":"crossref","first-page":"2272","DOI":"10.1046\/j.1523-1755.2003.00328.x","article-title":"Circulating concentration of FGF-23 increases as renal function declines in patients with chronic kidney disease, but does not change in response to variation in phosphate intake in healthy volunteers","volume":"64","author":"Larsson","year":"2003","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0135","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1681\/ASN.2007060673","article-title":"Postprandial mineral metabolism and secondary hyperparathyroidism in early CKD","volume":"19","author":"Isakova","year":"2008","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0140","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1038\/sj.ki.5002000","article-title":"Acute effect of oral phosphate loading on serum fibroblast growth factor 23 levels in healthy men","volume":"70","author":"Nishida","year":"2006","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0145","doi-asserted-by":"crossref","first-page":"F1088","DOI":"10.1152\/ajprenal.00474.2004","article-title":"Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism","volume":"289","author":"Shimada","year":"2005","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1038\/ki.2012.176_bb0150","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1038\/ki.2009.24","article-title":"Reversal of mineral ion homeostasis and soft-tissue calcification of klotho knockout mice by deletion of vitamin D 1alpha-hydroxylase","volume":"75","author":"Ohnishi","year":"2009","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0155","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1038\/ki.2011.107","article-title":"Direct and indirect effects of parathyroid hormone on circulating levels of fibroblast growth factor 23 in vivo","volume":"80","author":"Lopez","year":"2011","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0160","doi-asserted-by":"crossref","first-page":"2772","DOI":"10.1210\/jc.2009-1909","article-title":"The calcemic response to continuous parathyroid hormone (PTH)(1-34) infusion in end-stage kidney disease varies according to bone turnover: a potential role for PTH(7-84)","volume":"95","author":"Wesseling-Perry","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1038\/ki.2012.176_bb0165","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.bone.2011.06.025","article-title":"Parathyroid hormone receptor signaling in osteocytes increases the expression of fibroblast growth factor-23 in vitro and in vivo","volume":"49","author":"Rhee","year":"2011","journal-title":"Bone"},{"key":"10.1038\/ki.2012.176_bb0170","doi-asserted-by":"crossref","first-page":"4489","DOI":"10.1210\/jc.2004-0724","article-title":"FGF-23 is elevated by chronic hyperphosphatemia","volume":"89","author":"Gupta","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1038\/ki.2012.176_bb0175","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1359\/JBMR.050718","article-title":"Fibroblast growth factor-23 is regulated by 1alpha,25-dihydroxyvitamin D","volume":"20","author":"Collins","year":"2005","journal-title":"J Bone Miner Res"},{"issue":"Suppl","key":"10.1038\/ki.2012.176_bb0180","doi-asserted-by":"crossref","first-page":"167S","DOI":"10.1111\/j.1365-2265.1976.tb03824.x","article-title":"Treatment of hypoparathyroidism with 1,25-dihydroxycholecalciferol","volume":"5","author":"Hill","year":"1976","journal-title":"Clin Endocrinol"},{"key":"10.1038\/ki.2012.176_bb0185","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1038\/ki.2011.350","article-title":"PTH, FGF23, and calcium: it takes three to tango?","volume":"80","author":"Evenepoel","year":"2011","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0190","doi-asserted-by":"crossref","first-page":"826","DOI":"10.4065\/78.7.826","article-title":"Fibroblast growth factor 23 concentrations in humoral hypercalcemia of malignancy and hyperparathyroidism","volume":"78","author":"Singh","year":"2003","journal-title":"Mayo Clin Proc"},{"key":"10.1038\/ki.2012.176_bb0195","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/S0025-6196(11)61528-0","article-title":"Elevated fibroblast growth factor 23 in women with malignant ovarian tumors","volume":"80","author":"Tebben","year":"2005","journal-title":"Mayo Clin Proc"},{"key":"10.1038\/ki.2012.176_bb0200","doi-asserted-by":"crossref","first-page":"2332","DOI":"10.1210\/jc.2008-2396","article-title":"FGF23 elevation and hypophosphatemia after intravenous iron polymaltose: a prospective study","volume":"94","author":"Schouten","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1038\/ki.2012.176_bb0205","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/j.bone.2009.06.017","article-title":"Hypophosphatemia induced by intravenous administration of saccharated ferric oxide: another form of FGF23-related hypophosphatemia","volume":"45","author":"Shimizu","year":"2009","journal-title":"Bone"},{"key":"10.1038\/ki.2012.176_bb0210","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1159\/000327019","article-title":"Effect of intravenous saccharated ferric oxide on serum FGF23 and mineral metabolism in hemodialysis patients","volume":"33","author":"Takeda","year":"2011","journal-title":"Am J Nephrol"},{"key":"10.1038\/ki.2012.176_bb0215","doi-asserted-by":"crossref","first-page":"3541","DOI":"10.1210\/jc.2011-1239","article-title":"Iron modifies plasma FGF23 differently in autosomal dominant hypophosphatemic rickets and healthy humans","volume":"96","author":"Imel","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1038\/ki.2012.176_bb0220","doi-asserted-by":"crossref","first-page":"E1146","DOI":"10.1073\/pnas.1110905108","article-title":"Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice","volume":"108","author":"Farrow","year":"2011","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/ki.2012.176_bb0225","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1002\/jbmr.1546","article-title":"Mechanism of FGF23 processing in fibrous dysplasia","volume":"27","author":"Bhattacharyya","year":"2012","journal-title":"J Bone Miner Res"},{"key":"10.1038\/ki.2012.176_bb0230","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1053\/j.ajkd.2004.04.029","article-title":"Possible involvement of circulating fibroblast growth factor 23 in the development of secondary hyperparathyroidism associated with renal insufficiency","volume":"44","author":"Shigematsu","year":"2004","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/ki.2012.176_bb0235","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1681\/ASN.2005010052","article-title":"Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease","volume":"16","author":"Gutierrez","year":"2005","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0240","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1038\/ki.2010.107","article-title":"Fibroblast growth factor 23 and bone metabolism in children with chronic kidney disease","volume":"78","author":"van Husen","year":"2010","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0245","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1210\/jc.2009-1576","article-title":"The influence of glomerular filtration rate and age on fibroblast growth factor 23 serum levels in pediatric chronic kidney disease","volume":"95","author":"Bacchetta","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1038\/ki.2012.176_bb0250","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1038\/ki.2010.313","article-title":"Direct evidence for a causative role of FGF23 in the abnormal renal phosphate handling and vitamin D metabolism in rats with early-stage chronic kidney disease","volume":"78","author":"Hasegawa","year":"2010","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0255","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1038\/ki.2010.281","article-title":"FGF23 or PTH: which comes first in CKD?","volume":"78","author":"Isakova","year":"2010","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0260","doi-asserted-by":"crossref","first-page":"S148","DOI":"10.1097\/01.ASN.0000070149.78399.CE","article-title":"The Chronic Renal Insufficiency Cohort (CRIC) Study: design and methods","volume":"14","author":"Feldman","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0265","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1038\/ki.2011.47","article-title":"Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease","volume":"79","author":"Isakova","year":"2011","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0270","doi-asserted-by":"crossref","first-page":"2688","DOI":"10.2215\/CJN.04290511","article-title":"Fibroblast growth factor 23 in patients undergoing peritoneal dialysis","volume":"6","author":"Isakova","year":"2011","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0275","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1093\/ndt\/gfr596","article-title":"Residual renal function is an independent determinant of serum FGF-23 levels in dialysis patients","volume":"27","author":"Viaene","year":"2012","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2012.176_bb0280","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1359\/jbmr.2003.18.7.1227","article-title":"Serum FGF23 levels in normal and disordered phosphorus homeostasis","volume":"18","author":"Weber","year":"2003","journal-title":"J Bone Miner Res"},{"key":"10.1038\/ki.2012.176_bb0285","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1210\/jc.2009-1603","article-title":"Circulating fibroblast growth factor 23 in patients with end-stage renal disease treated by peritoneal dialysis is intact and biologically active","volume":"95","author":"Shimada","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1038\/ki.2012.176_bb0290","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1111\/j.1523-1755.2005.00184.x","article-title":"Serum fibroblast growth factor-23 levels predict the future refractory hyperparathyroidism in dialysis patients","volume":"67","author":"Nakanishi","year":"2005","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0295","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1056\/NEJMoa0706130","article-title":"Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis","volume":"359","author":"Gutierrez","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.2012.176_bb0300","doi-asserted-by":"crossref","first-page":"p23","DOI":"10.1159\/000093277","article-title":"FGF-23 and sFRP-4 in chronic kidney disease and post-renal transplantation","volume":"104","author":"Pande","year":"2006","journal-title":"Nephron Physiol"},{"key":"10.1038\/ki.2012.176_bb0305","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1038\/sj.ki.5001788","article-title":"Post-transplant hypophosphatemia: Tertiary \u2018Hyper-Phosphatoninism\u2019?","volume":"70","author":"Bhan","year":"2006","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0310","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.2215\/CJN.01310308","article-title":"Recovery of hyperphosphatoninism and renal phosphorus wasting one year after successful renal transplantation","volume":"3","author":"Evenepoel","year":"2008","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0315","doi-asserted-by":"crossref","first-page":"379082","DOI":"10.1155\/2009\/379082","article-title":"FGF-23 levels before and after renal transplantation","volume":"2009","author":"Economidou","year":"2009","journal-title":"J Transplant"},{"key":"10.1038\/ki.2012.176_bb0320","doi-asserted-by":"crossref","first-page":"323","DOI":"10.2215\/CJN.06380611","article-title":"Renal phosphate loss in long-term kidney transplantation","volume":"7","author":"Sirilak","year":"2012","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0325","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1056\/NEJM199108223250804","article-title":"Rapid loss of vertebral mineral density after renal transplantation","volume":"325","author":"Julian","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.2012.176_bb0330","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.jbspin.2010.11.007","article-title":"Normal plasma FGF23 levels kinetic in tenofovir-related hypophosphatemic osteomalacia in an HIV-infected patient with von Recklinghausen disease","volume":"78","author":"Saidenberg-Kermanac\u2019h","year":"2011","journal-title":"Joint Bone Spine"},{"key":"10.1038\/ki.2012.176_bb0335","doi-asserted-by":"crossref","first-page":"4433","DOI":"10.1210\/jc.2009-1535","article-title":"Hypophosphatemic rickets with hypercalciuria due to mutation in SLC34A3\/type IIc sodium-phosphate cotransporter: presentation as hypercalciuria and nephrolithiasis","volume":"94","author":"Tencza","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1038\/ki.2012.176_bb0340","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1097\/00005792-194305000-00002","article-title":"Studies on calcium and phosphorus metabolism with special reference to pathogenesis and effect of dihydrotachysterol (A.T. 10) and iron","volume":"22","author":"Liu","year":"1943","journal-title":"Medicine"},{"key":"10.1038\/ki.2012.176_bb0345","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1172\/JCI105530","article-title":"The effect of treatment of acidosis on calcium balance in patients with chronic azotemic renal disease","volume":"46","author":"Litzow","year":"1967","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.2012.176_bb0350","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1038\/ki.2010.375","article-title":"Patients with autosomal dominant polycystic kidney disease have elevated fibroblast growth factor 23 levels and a renal leak of phosphate","volume":"79","author":"Pavik","year":"2011","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0355","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/36285","article-title":"Mutation of the mouse klotho gene leads to a syndrome resembling ageing","volume":"390","author":"Kuro-o","year":"1997","journal-title":"Nature"},{"key":"10.1038\/ki.2012.176_bb0360","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1002\/jbmr.516","article-title":"Longitudinal evaluation of FGF23 changes and mineral metabolism abnormalities in a mouse model of chronic kidney disease","volume":"1","author":"Stubbs","year":"2012","journal-title":"J Bone Miner Res"},{"key":"10.1038\/ki.2012.176_bb0365","doi-asserted-by":"crossref","first-page":"2393","DOI":"10.1210\/me.2003-0048","article-title":"Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system","volume":"17","author":"Tsujikawa","year":"2003","journal-title":"Mol Endocrinol"},{"key":"10.1038\/ki.2012.176_bb0370","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.bbrc.2011.09.117","article-title":"Vitamin D receptor controls expression of the anti-aging klotho gene in mouse and human renal cells","volume":"414","author":"Forster","year":"2011","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1038\/ki.2012.176_bb0375","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1093\/ndt\/gfm672","article-title":"Gene expression analysis of kidneys from transgenic mice expressing fibroblast growth factor-23","volume":"23","author":"Marsell","year":"2008","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2012.176_bb0380","doi-asserted-by":"crossref","first-page":"4835","DOI":"10.1210\/en.2009-0472","article-title":"Bone formation regulates circulating concentrations of fibroblast growth factor 23","volume":"150","author":"Samadfam","year":"2009","journal-title":"Endocrinology"},{"key":"10.1038\/ki.2012.176_bb0385","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1038\/ng1106-1230","article-title":"Bone talk","volume":"38","author":"Schiavi","year":"2006","journal-title":"Nat Genet"},{"key":"10.1038\/ki.2012.176_bb0390","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/ki.2009.464","article-title":"Parathyroid cell resistance to fibroblast growth factor 23 in secondary hyperparathyroidism of chronic kidney disease","volume":"77","author":"Galitzer","year":"2010","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0395","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1038\/ki.2009.414","article-title":"Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients","volume":"77","author":"Komaba","year":"2010","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0400","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1681\/ASN.2009040427","article-title":"FGF23 fails to inhibit uremic parathyroid glands","volume":"21","author":"Canalejo","year":"2010","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0405","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1681\/ASN.2009121311","article-title":"Klotho deficiency causes vascular calcification in chronic kidney disease","volume":"22","author":"Hu","year":"2011","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0410","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1002\/jbmr.170","article-title":"FGF-23: More than a regulator of renal phosphate handling?","volume":"25","author":"Juppner","year":"2010","journal-title":"J Bone Miner Res"},{"key":"10.1038\/ki.2012.176_bb0415","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1097\/MAJ.0b013e3181815498","article-title":"Fibroblast growth factor 23: a possible cause of left ventricular hypertrophy in hemodialysis patients","volume":"337","author":"Hsu","year":"2009","journal-title":"Am J Med Sci"},{"key":"10.1038\/ki.2012.176_bb0420","doi-asserted-by":"crossref","first-page":"3033","DOI":"10.1093\/ndt\/gfq191","article-title":"Relation between serum fibroblast growth factor-23 level and mortality in incident dialysis patients: are gender and cardiovascular disease confounding the relationship?","volume":"25","author":"Olauson","year":"2010","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2012.176_bb0425","doi-asserted-by":"crossref","first-page":"2792","DOI":"10.1093\/ndt\/gfp191","article-title":"High levels of serum fibroblast growth factor (FGF)-23 are associated with increased mortality in long haemodialysis patients","volume":"24","author":"Jean","year":"2009","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2012.176_bb0430","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1681\/ASN.2010080894","article-title":"Elevated fibroblast growth factor 23 is a risk factor for kidney transplant loss and mortality","volume":"22","author":"Wolf","year":"2011","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0435","doi-asserted-by":"crossref","first-page":"2432","DOI":"10.1001\/jama.2011.826","article-title":"Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease","volume":"305","author":"Isakova","year":"2011","journal-title":"JAMA"},{"key":"10.1038\/ki.2012.176_bb0440","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1681\/ASN.2010121224","article-title":"FGF-23 associates with death, cardiovascular events, and initiation of chronic dialysis","volume":"22","author":"Kendrick","year":"2011","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0445","doi-asserted-by":"crossref","first-page":"2600","DOI":"10.1681\/ASN.2006080936","article-title":"Fibroblast growth factor 23 (FGF23) predicts progression of chronic kidney disease: the Mild to Moderate Kidney Disease (MMKD) Study","volume":"18","author":"Fliser","year":"2007","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0450","doi-asserted-by":"crossref","first-page":"241","DOI":"10.2215\/CJN.04250510","article-title":"FGF-23 as a predictor of renal outcome in diabetic nephropathy","volume":"6","author":"Titan","year":"2011","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0455","doi-asserted-by":"crossref","first-page":"3983","DOI":"10.1093\/ndt\/gfq309","article-title":"FGF-23 and future cardiovascular events in patients with chronic kidney disease before initiation of dialysis treatment","volume":"25","author":"Seiler","year":"2010","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2012.176_bb0460","doi-asserted-by":"crossref","first-page":"640","DOI":"10.7326\/0003-4819-152-10-201005180-00004","article-title":"The associations of fibroblast growth factor 23 and uncarboxylated matrix Gla protein with mortality in coronary artery disease: the Heart and Soul Study","volume":"152","author":"Parker","year":"2010","journal-title":"Ann Intern Med"},{"key":"10.1038\/ki.2012.176_bb0465","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1016\/j.ahj.2011.02.012","article-title":"Plasma fibroblast growth factor 23, parathyroid hormone, phosphorus, and risk of coronary heart disease","volume":"161","author":"Taylor","year":"2011","journal-title":"Am Heart J"},{"key":"10.1038\/ki.2012.176_bb0470","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1007\/s00198-009-1142-4","article-title":"Fibroblast growth factor-23 is associated with C-reactive protein, serum phosphate and bone mineral density in chronic kidney disease","volume":"21","author":"Manghat","year":"2010","journal-title":"Osteoporos Int"},{"key":"10.1038\/ki.2012.176_bb0475","doi-asserted-by":"crossref","first-page":"2688","DOI":"10.1093\/eurheartj\/ehr215","article-title":"The phosphatonin fibroblast growth factor 23 links calcium-phosphate metabolism with left-ventricular dysfunction and atrial fibrillation","volume":"32","author":"Seiler","year":"2011","journal-title":"Eur Heart J"},{"key":"10.1038\/ki.2012.176_bb0480","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/j.bone.2009.07.016","article-title":"The impact of diabetes mellitus on vitamin D metabolism in predialysis patients","volume":"45","author":"Tanaka","year":"2009","journal-title":"Bone"},{"key":"10.1038\/ki.2012.176_bb0485","doi-asserted-by":"crossref","first-page":"994","DOI":"10.2337\/dc11-2235","article-title":"Earlier onset and greater severity of disordered mineral metabolism in diabetic patients with chronic kidney disease","volume":"35","author":"Wahl","year":"2012","journal-title":"Diabetes Care"},{"key":"10.1038\/ki.2012.176_bb0490","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1038\/ki.2010.194","article-title":"FGF-23 and vascular dysfunction in patients with stage 3 and 4 chronic kidney disease","volume":"78","author":"Yilmaz","year":"2010","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0495","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.atherosclerosis.2009.01.001","article-title":"Circulating fibroblast growth factor-23 is associated with vascular dysfunction in the community","volume":"205","author":"Mirza","year":"2009","journal-title":"Atherosclerosis"},{"key":"10.1038\/ki.2012.176_bb0500","series-title":"Osteoporos Int","article-title":"FGF23 is independently associated with vascular calcification but not bone mineral density in patients at various CKD stages","author":"Desjardins","year":"2011"},{"key":"10.1038\/ki.2012.176_bb0505","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1007\/s00467-011-1822-0","article-title":"Elevated FGF 23 and phosphorus are associated with coronary calcification in hemodialysis patients","volume":"26","author":"Srivaths","year":"2011","journal-title":"Pediatr Nephrol"},{"key":"10.1038\/ki.2012.176_bb0510","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1111\/j.1365-2265.2007.03074.x","article-title":"Relation between plasma fibroblast growth factor-23, serum fetuin-A levels and coronary artery calcification evaluated by multislice computed tomography in patients with normal kidney function","volume":"68","author":"Roos","year":"2008","journal-title":"Clin Endocrinol"},{"key":"10.1038\/ki.2012.176_bb0515","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1007\/s00198-006-0154-6","article-title":"Role of fibroblast growth factor-23 in peripheral vascular calcification in non-diabetic and diabetic hemodialysis patients","volume":"17","author":"Inaba","year":"2006","journal-title":"Osteoporos Int"},{"key":"10.1038\/ki.2012.176_bb0520","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1056\/NEJM200005183422003","article-title":"Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis","volume":"342","author":"Goodman","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.2012.176_bb0525","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1161\/hy1001.096358","article-title":"Arterial calcifications, arterial stiffness, and cardiovascular risk in end-stage renal disease","volume":"38","author":"Blacher","year":"2001","journal-title":"Hypertension"},{"key":"10.1038\/ki.2012.176_bb0530","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1111\/j.1523-1755.2005.00421.x","article-title":"Pathogenesis of vascular calcification in chronic kidney disease","volume":"68","author":"Cozzolino","year":"2005","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0535","doi-asserted-by":"crossref","first-page":"E10","DOI":"10.1161\/01.RES.87.7.e10","article-title":"Phosphate regulation of vascular smooth muscle cell calcification","volume":"87","author":"Jono","year":"2000","journal-title":"Circ Res"},{"key":"10.1038\/ki.2012.176_bb0540","doi-asserted-by":"crossref","first-page":"2857","DOI":"10.1097\/01.ASN.0000141960.01035.28","article-title":"Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD","volume":"15","author":"Reynolds","year":"2004","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0545","doi-asserted-by":"crossref","first-page":"2996","DOI":"10.1681\/ASN.2006121397","article-title":"Mineral metabolism and vascular damage in children on dialysis","volume":"18","author":"Shroff","year":"2007","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0550","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1038\/ki.1989.192","article-title":"Impact of left ventricular hypertrophy on survival in end-stage renal disease","volume":"36","author":"Silberberg","year":"1989","journal-title":"Kidney Int"},{"issue":"Suppl 1","key":"10.1038\/ki.2012.176_bb0555","doi-asserted-by":"crossref","first-page":"S79","DOI":"10.2215\/CJN.04860709","article-title":"Left ventricular mass in chronic kidney disease and ESRD","volume":"4","author":"Glassock","year":"2009","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0560","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1161\/CIRCULATIONAHA.108.844506","article-title":"Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney disease","volume":"119","author":"Gutierrez","year":"2009","journal-title":"Circulation"},{"key":"10.1038\/ki.2012.176_bb0565","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.atherosclerosis.2009.05.013","article-title":"Serum intact FGF23 associate with left ventricular mass, hypertrophy and geometry in an elderly population","volume":"207","author":"Mirza","year":"2009","journal-title":"Atherosclerosis"},{"key":"10.1038\/ki.2012.176_bb0570","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1093\/ndt\/gfq539","article-title":"Serum fibroblast growth factor-23 (FGF-23) levels are independently associated with left ventricular mass and myocardial performance index in maintenance haemodialysis patients","volume":"26","author":"Kirkpantur","year":"2011","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2012.176_bb0575","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1159\/000321368","article-title":"Fibroblast growth factor 23 in chronic kidney disease: bridging the gap between bone mineral metabolism and left ventricular hypertrophy","volume":"31","author":"Canziani","year":"2011","journal-title":"Blood Purif"},{"key":"10.1038\/ki.2012.176_bb0580","doi-asserted-by":"crossref","first-page":"297070","DOI":"10.4061\/2011\/297070","article-title":"Fibroblast growth factor 23 predicts left ventricular mass and induces cell adhesion molecule formation","volume":"2011","author":"Stevens","year":"2011","journal-title":"Int J Nephrol"},{"key":"10.1038\/ki.2012.176_bb0585","doi-asserted-by":"crossref","first-page":"4393","DOI":"10.1172\/JCI46122","article-title":"FGF23 induces left ventricular hypertrophy","volume":"121","author":"Faul","year":"2011","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.2012.176_bb0590","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1111\/j.1525-139X.2008.00454.x","article-title":"Hypertrophy and fibrosis in the cardiomyopathy of uremia--beyond coronary heart disease","volume":"21","author":"Gross","year":"2008","journal-title":"Semin Dial"},{"key":"10.1038\/ki.2012.176_bb0595","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1056\/NEJMoa043545","article-title":"Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis","volume":"353","author":"Wanner","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.2012.176_bb0600","series-title":"US Renal Data System, USRDS 2010 Annual Data Report: Atlas of Chronic Kidney Disease and End-Stage Renal Disease in the United States","author":"National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases","year":"2010"},{"key":"10.1038\/ki.2012.176_bb0605","doi-asserted-by":"crossref","first-page":"123","DOI":"10.2215\/CJN.06320611","article-title":"Predictors of sudden cardiac death: a competing risk approach in the hemodialysis study","volume":"7","author":"Shastri","year":"2012","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0610","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1093\/ndt\/gfq419","article-title":"Pilot study of dietary phosphorus restriction and phosphorus binders to target fibroblast growth factor 23 in patients with chronic kidney disease","volume":"26","author":"Isakova","year":"2011","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2012.176_bb0615","doi-asserted-by":"crossref","first-page":"257","DOI":"10.2215\/CJN.05040610","article-title":"Vegetarian compared with meat dietary protein source and phosphorus homeostasis in chronic kidney disease","volume":"6","author":"Moe","year":"2011","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0620","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1046\/j.1525-139X.2003.16037.x","article-title":"Hidden sources of phosphorus in the typical American diet: does it matter in nephrology?","volume":"16","author":"Uribarri","year":"2003","journal-title":"Semin Dial"},{"key":"10.1038\/ki.2012.176_bb0625","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1038\/ki.2008.456","article-title":"A rat model of chronic kidney disease-mineral bone disorder","volume":"75","author":"Moe","year":"2009","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0630","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1111\/j.1744-9987.2005.00293.x","article-title":"Sevelamer hydrochloride and calcium bicarbonate reduce serum fibroblast growth factor 23 levels in dialysis patients","volume":"9","author":"Koiwa","year":"2005","journal-title":"Ther Apher Dial"},{"key":"10.1038\/ki.2012.176_bb0635","doi-asserted-by":"crossref","first-page":"286","DOI":"10.2215\/CJN.05420709","article-title":"Early control of PTH and FGF23 in normophosphatemic CKD patients: a new target in CKD-MBD therapy?","volume":"5","author":"Oliveira","year":"2010","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0640","doi-asserted-by":"crossref","first-page":"2567","DOI":"10.1093\/ndt\/gfr144","article-title":"Lanthanum carbonate reduces FGF23 in chronic kidney disease stage 3 patients","volume":"26","author":"Gonzalez-Parra","year":"2011","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2012.176_bb0645","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1053\/j.ajkd.2011.11.007","article-title":"Comparison of calcium acetate and sevelamer on vascular function and fibroblast growth factor 23 in CKD patients: a randomized clinical trial","volume":"59","author":"Yilmaz","year":"2012","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/ki.2012.176_bb0650","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1038\/ki.2009.246","article-title":"A blueprint for randomized trials targeting phosphorus metabolism in chronic kidney disease","volume":"76","author":"Isakova","year":"2009","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0655","doi-asserted-by":"crossref","first-page":"110","DOI":"10.2215\/CJN.03630509","article-title":"Effects of cinacalcet and concurrent low-dose vitamin D on FGF23 levels in ESRD","volume":"5","author":"Wetmore","year":"2010","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0660","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1093\/ndt\/gfr384","article-title":"Cinacalcet treatment and serum FGF23 levels in haemodialysis patients with secondary hyperparathyroidism","volume":"27","author":"Koizumi","year":"2012","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2012.176_bb0665","doi-asserted-by":"crossref","first-page":"F1315","DOI":"10.1152\/ajprenal.00552.2009","article-title":"Effect of paricalcitol and cinacalcet on serum phosphate, FGF-23, and bone in rats with chronic kidney disease","volume":"298","author":"Finch","year":"2010","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1038\/ki.2012.176_bb0670","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1038\/sj.ki.5002451","article-title":"Vitamin D levels and early mortality among incident hemodialysis patients","volume":"72","author":"Wolf","year":"2007","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0675","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1056\/NEJMoa031633","article-title":"Cinacalcet for secondary hyperparathyroidism in patients receiving hemodialysis","volume":"350","author":"Block","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.2012.176_bb0680","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1053\/j.ajkd.2005.04.013","article-title":"Cinacalcet hydrochloride is an effective treatment for secondary hyperparathyroidism in patients with CKD not receiving dialysis","volume":"46","author":"Charytan","year":"2005","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/ki.2012.176_bb0685","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/ki.2010.352","article-title":"Calcitriol and doxercalciferol are equivalent in controlling bone turnover, suppressing parathyroid hormone, and increasing fibroblast growth factor-23 in secondary hyperparathyroidism","volume":"79","author":"Wesseling-Perry","year":"2011","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0690","series-title":"Nephrol Dial Transplant","article-title":"Changes in fibroblast growth factor 23 during treatment of secondary hyperparathyroidism with alfacalcidol or paricalcitol","author":"Hansen","year":"2011"},{"key":"10.1038\/ki.2012.176_bb0695","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1056\/NEJMoa022536","article-title":"Survival of patients undergoing hemodialysis with paricalcitol or calcitriol therapy","volume":"349","author":"Teng","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.2012.176_bb0700","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1681\/ASN.2004070573","article-title":"Activated injectable vitamin D and hemodialysis survival: a historical cohort study","volume":"16","author":"Teng","year":"2005","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0705","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1681\/ASN.2007111164","article-title":"Association of oral calcitriol with improved survival in nondialyzed CKD","volume":"19","author":"Shoben","year":"2008","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0710","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1001\/archinternmed.2007.110","article-title":"Association of activated vitamin D treatment and mortality in chronic kidney disease","volume":"168","author":"Kovesdy","year":"2008","journal-title":"Arch Intern Med"},{"key":"10.1038\/ki.2012.176_bb0715","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1038\/ki.2008.343","article-title":"Oral active vitamin D is associated with improved survival in hemodialysis patients","volume":"74","author":"Naves-Diaz","year":"2008","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0720","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1038\/sj.ki.5001514","article-title":"Survival predictability of time-varying indicators of bone disease in maintenance hemodialysis patients","volume":"70","author":"Kalantar-Zadeh","year":"2006","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.176_bb0725","doi-asserted-by":"crossref","first-page":"820","DOI":"10.2215\/CJN.11721111","article-title":"Daily variability in mineral metabolites in CKD and effects of dietary calcium and calcitriol","volume":"7","author":"Isakova","year":"2012","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.176_bb0730","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1359\/jbmr.090509","article-title":"Therapeutic effects of anti-FGF23 antibodies in hypophosphatemic rickets\/osteomalacia","volume":"24","author":"Aono","year":"2009","journal-title":"J Bone Miner Res"},{"key":"10.1038\/ki.2012.176_bb0735","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1172\/JCI200419081","article-title":"Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism","volume":"113","author":"Shimada","year":"2004","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.2012.176_bb0740","first-page":"295","article-title":"The environment and disease: association or causation?","volume":"58","author":"Hill","year":"1965","journal-title":"Proc R Soc Med"},{"key":"10.1038\/ki.2012.176_bb0745","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1097\/MNH.0b013e328338f536","article-title":"Recent advances in the rapidly evolving field of fibroblast growth factor 23 in chronic kidney disease","volume":"19","author":"Zisman","year":"2010","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"10.1038\/ki.2012.176_bb0750","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1056\/NEJMoa020881","article-title":"Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia","volume":"348","author":"Jonsson","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.2012.176_bb0755","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1086\/499410","article-title":"Hereditary hypophosphatemic rickets with hypercalciuria is caused by mutations in the sodium-phosphate cotransporter gene SLC34A3","volume":"78","author":"Lorenz-Depiereux","year":"2006","journal-title":"Am J Hum Genet"},{"key":"10.1038\/ki.2012.176_bb0760","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/j.bone.2012.02.015","article-title":"Novel NaPi-IIc mutations causing HHRH and idiopathic hypercalciuria in several unrelated families: long-term follow-up in one kindred","volume":"50","author":"Yu","year":"2012","journal-title":"Bone"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815556299?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815556299?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,28]],"date-time":"2019-06-28T21:35:24Z","timestamp":1561757724000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815556299"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":151,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["S0085253815556299"],"URL":"https:\/\/doi.org\/10.1038\/ki.2012.176","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10]]}}}