{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T20:43:01Z","timestamp":1791924181930,"version":"4.3.4"},"reference-count":21,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"vor","delay-in-days":1461,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1038\/ki.2012.263","type":"journal-article","created":{"date-parts":[[2012,7,25]],"date-time":"2012-07-25T08:42:48Z","timestamp":1343205768000},"page":"114-120","source":"Crossref","is-referenced-by-count":226,"title":["Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans"],"prefix":"10.1016","volume":"83","author":[{"given":"Michael S.","family":"Lipkowitz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barry I.","family":"Freedman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl D.","family":"Langefeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary E.","family":"Comeau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald W.","family":"Bowden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.H.","family":"Linda Kao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brad C.","family":"Astor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erwin P.","family":"Bottinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudha K.","family":"Iyengar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul E.","family":"Klotman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard G.","family":"Freedman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weijia","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rulan S.","family":"Parekh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George W.","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheryl A.","family":"Winkler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey B.","family":"Kopp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/ki.2012.263_bb0010","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1097\/01.ASN.0000014251.87778.01","article-title":"Cumulative risk for developing end-stage renal disease in the US population","volume":"13","author":"Kiberd","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2012.263_bb0015","series-title":"Annual Data Report: Atlas of Chronic Kidney Disease and End-Stage Renal Disease in the United States","author":"US Renal Data System, USRDS","year":"2011"},{"key":"10.1038\/ki.2012.263_bb0020","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1038\/ng.232","article-title":"MYH9 is associated with nondiabetic end-stage renal disease in African Americans","volume":"40","author":"Kao","year":"2008","journal-title":"Nat Genet"},{"key":"10.1038\/ki.2012.263_bb0025","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1038\/ng.226","article-title":"MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis","volume":"40","author":"Kopp","year":"2008","journal-title":"Nat Genet"},{"key":"10.1038\/ki.2012.263_bb0030","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1038\/ki.2008.701","article-title":"Polymorphisms in the non-muscle myosin heavy chain 9 gene (MYH9) are strongly associated with end-stage renal disease historically attributed to hypertension in African Americans","volume":"75","author":"Freedman","year":"2009","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.263_bb0035","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1126\/science.1193032","article-title":"Association of trypanolytic ApoL1 variants with kidney disease in African Americans","volume":"329","author":"Genovese","year":"2010","journal-title":"Science"},{"key":"10.1038\/ki.2012.263_bb0040","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1007\/s00439-010-0861-0","article-title":"Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene","volume":"128","author":"Tzur","year":"2010","journal-title":"Hum Genet"},{"key":"10.1038\/ki.2012.263_bb0045","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1093\/ndt\/gfr522","article-title":"Polymorphisms in MYH9 are associated with diabetic nephropathy in European Americans","volume":"27","author":"Cooke","year":"2012","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2012.263_bb0050","doi-asserted-by":"crossref","first-page":"2450","DOI":"10.1093\/hmg\/ddr118","article-title":"The MYH9\/APOL1 region and chronic kidney disease in European-Americans","volume":"20","author":"O'Seaghdha","year":"2011","journal-title":"Hum Mol Genet"},{"key":"10.1038\/ki.2012.263_bb0055","doi-asserted-by":"crossref","first-page":"3S","DOI":"10.1016\/S0197-2456(96)00081-5","article-title":"Design and baseline characteristics of participants in the African American Study of Kidney Disease and Hypertension (AASK) Pilot Study","volume":"17","author":"Wright","year":"1996","journal-title":"Control Clin Trials"},{"key":"10.1038\/ki.2012.263_bb0060","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1056\/NEJMoa0910975","article-title":"Intensive blood-pressure control in hypertensive chronic kidney disease","volume":"363","author":"Appel","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1038\/ki.2012.263_bb0065","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1038\/ki.1997.29","article-title":"Accuracy of the diagnosis of hypertensive nephrosclerosis in African Americans: a report from the African American Study of Kidney Disease (AASK) Trial. AASK Pilot Study Investigators","volume":"51","author":"Fogo","year":"1997","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.263_bb0070","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1001\/archinte.168.8.832","article-title":"Long-term effects of renin-angiotensin system-blocking therapy and a low blood pressure goal on progression of hypertensive chronic kidney disease in African Americans","volume":"168","author":"Appel","year":"2008","journal-title":"Arch Intern Med"},{"key":"10.1038\/ki.2012.263_bb0075","doi-asserted-by":"crossref","first-page":"I80","DOI":"10.1161\/01.HYP.13.5_Suppl.I80","article-title":"Prognostic value of serum creatinine and effect of treatment of hypertension on renal function. Results from the hypertension detection and follow-up program. The Hypertension Detection and Follow-up Program Cooperative Group","volume":"13","author":"Shulman","year":"1989","journal-title":"Hypertension"},{"key":"10.1038\/ki.2012.263_bb0080","doi-asserted-by":"crossref","first-page":"3085","DOI":"10.1001\/jama.1992.03490210067037","article-title":"Renal function change in hypertensive members of the Multiple Risk Factor Intervention Trial. Racial and treatment effects. The MRFIT Research Group","volume":"268","author":"Walker","year":"1992","journal-title":"JAMA"},{"key":"10.1038\/ki.2012.263_bb0085","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1046\/j.1523-1755.2002.00420.x","article-title":"Hypertensive nephrosclerosis in African Americans vs. Caucasians","volume":"62","author":"Marcantoni","year":"2002","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2012.263_bb0090","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1111\/j.1600-6143.2011.03513.x","article-title":"The APOL1 gene and allograft survival after kidney transplantation","volume":"11","author":"Reeves-Daniel","year":"2011","journal-title":"Am J Transplant"},{"key":"10.1038\/ki.2012.263_bb0095","doi-asserted-by":"crossref","first-page":"2421","DOI":"10.1001\/jama.288.19.2421","article-title":"Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: results from the AASK trial","volume":"288","author":"Wright","year":"2002","journal-title":"JAMA"},{"key":"10.1038\/ki.2012.263_bb0100","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1159\/000313927","article-title":"Progression of chronic kidney disease: adrenergic genetic influence on glomerular filtration rate decline in hypertensive nephrosclerosis","volume":"32","author":"Chen","year":"2010","journal-title":"Am J Nephrol"},{"key":"10.1038\/ki.2012.263_bb0105","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1093\/ndt\/gfr257","article-title":"Methylenetetrahydrofolate reductase (MTHFR) polymorphism A1298C (Glu429Ala) predicts decline in renal function over time in the African-American Study of Kidney Disease and Hypertension (AASK) Trial and Veterans Affairs Hypertension Cohort (VAHC)","volume":"27","author":"Fung","year":"2012","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2012.263_bb0110","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1111\/j.1365-2141.2011.08832.x","article-title":"MYH9 and APOL1 are both associated with sickle cell disease nephropathy","volume":"155","author":"Ashley-Koch","year":"2011","journal-title":"Br J Haematol"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815556871?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815556871?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T13:18:49Z","timestamp":1561987129000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815556871"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S0085253815556871"],"URL":"https:\/\/doi.org\/10.1038\/ki.2012.263","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}