{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T14:00:51Z","timestamp":1770818451181,"version":"3.50.1"},"reference-count":6,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"vor","delay-in-days":1461,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2014]]},"DOI":"10.1038\/ki.2013.371","type":"journal-article","created":{"date-parts":[[2014,1,31]],"date-time":"2014-01-31T16:51:59Z","timestamp":1391187119000},"page":"236-237","source":"Crossref","is-referenced-by-count":2,"title":["The importance of quantifying genetic heterogeneity in ADPKD"],"prefix":"10.1016","volume":"85","author":[{"given":"Arlene B.","family":"Chapman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1038\/ki.2013.371_bb0010","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1038\/ki.2013.227","article-title":"Evidence of a third ADPKD locus is not supported by re-analysis of designated PKD3 families","volume":"85","author":"Paul","year":"2014","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2013.371_bb0015","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0140-6736(98)03495-3","article-title":"Comparison of phenotypes of polycystic kidney disease types 1 and 2. European PKD1-PKD2 Study Group","volume":"353","author":"Hateboer","year":"1999","journal-title":"Lancet"},{"key":"10.1038\/ki.2013.371_bb0020","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1038\/ki.2008.485","article-title":"Characterization of large rearrangements in autosomal dominant polycystic kidney disease and the PKD1\/TSC2 contiguous gene syndrome","volume":"74","author":"Consugar","year":"2008","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2013.371_bb0025","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/S0272-6386(83)80044-4","article-title":"Epidemiology of adult polycystic kidney disease, Olmsted County, Minnesota: 1935\u20131980","volume":"2","author":"Iglesias","year":"1983","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/ki.2013.371_bb0030","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1038\/ki.2011.370","article-title":"A missense mutation in PKD1 attenuates the severity of renal disease","volume":"81","author":"Pei","year":"2012","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2013.371_bb0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S1462399406010362","article-title":"Molecular pathogenesis of autosomal dominant polycystic kidney disease","volume":"8","author":"Yoder","year":"2006","journal-title":"Expert Rev Mol Med"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S008525381556198X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S008525381556198X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,7,21]],"date-time":"2021-07-21T11:52:38Z","timestamp":1626868358000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S008525381556198X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":6,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014]]}},"alternative-id":["S008525381556198X"],"URL":"https:\/\/doi.org\/10.1038\/ki.2013.371","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2014]]}}}