{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T09:52:54Z","timestamp":1790761974961,"version":"4.1.0"},"reference-count":20,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"vor","delay-in-days":1461,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1038\/ki.2014.235","type":"journal-article","created":{"date-parts":[[2014,7,9]],"date-time":"2014-07-09T12:39:40Z","timestamp":1404909580000},"page":"233-238","source":"Crossref","is-referenced-by-count":89,"title":["The contribution of epithelial-mesenchymal transition to renal fibrosis differs among kidney disease models"],"prefix":"10.1016","volume":"87","author":[{"given":"Tsutomu","family":"Inoue","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiro","family":"Umezawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsuneo","family":"Takenaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromichi","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirokazu","family":"Okada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/ki.2014.235_bb0010","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1172\/JCI0215518","article-title":"Evidence that fibroblasts derive from epithelium during tissue fibrosis","volume":"110","author":"Iwano","year":"2002","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.2014.235_bb0015","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1172\/JCI36183","article-title":"Biomarkers for epithelial-mesenchymal transitions","volume":"119","author":"Zeisberg","year":"2009","journal-title":"J Clin Invest"},{"key":"10.1038\/ki.2014.235_bb0020","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/ki.2011.77","article-title":"Scar wars: mapping the fate of epithelial-mesenchymal-myofibroblast transition","volume":"80","author":"Quaggin","year":"2011","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2014.235_bb0025","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/s10157-009-0168-4","article-title":"A case report suggesting the occurrence of epithelial-mesenchymal transition in obstructive nephropathy","volume":"13","author":"Inoue","year":"2009","journal-title":"Clin Exp Nephrol"},{"key":"10.1038\/ki.2014.235_bb0030","doi-asserted-by":"crossref","first-page":"85","DOI":"10.2353\/ajpath.2010.090517","article-title":"Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis","volume":"176","author":"Humphreys","year":"2010","journal-title":"Am J Pathol"},{"key":"10.1038\/ki.2014.235_bb0035","doi-asserted-by":"crossref","first-page":"632","DOI":"10.2353\/ajpath.2010.091012","article-title":"Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells","volume":"177","author":"Koesters","year":"2010","journal-title":"Am J Pathol"},{"key":"10.1038\/ki.2014.235_bb0040","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.2353\/ajpath.2008.080433","article-title":"Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney","volume":"173","author":"Lin","year":"2008","journal-title":"Am J Pathol"},{"key":"10.1038\/ki.2014.235_bb0045","doi-asserted-by":"crossref","first-page":"R215","DOI":"10.1186\/bcr778","article-title":"Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro","volume":"6","author":"Brown","year":"2004","journal-title":"Breast Cancer Res"},{"key":"10.1038\/ki.2014.235_bb0050","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1096\/fj.02-0442fje","article-title":"Hepatocyte growth factor counteracts transforming growth factor-beta1, through attenuation of connective tissue growth factor induction, and prevents renal fibrogenesis in 5\/6 nephrectomized mice","volume":"17","author":"Inoue","year":"2003","journal-title":"FASEB J"},{"key":"10.1038\/ki.2014.235_bb0055","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1038\/ki.2008.7","article-title":"Mapping quantitative trait loci for proteinuria-induced renal collagen deposition","volume":"73","author":"Kato","year":"2008","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2014.235_bb0060","doi-asserted-by":"crossref","first-page":"F1624","DOI":"10.1152\/ajprenal.00032.2008","article-title":"Serum- and glucocorticoid-inducible kinase 1 in doxorubicin-induced nephrotic syndrome","volume":"295","author":"Artunc","year":"2008","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1038\/ki.2014.235_bb0065","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1046\/j.1523-1755.2003.00058.x","article-title":"Model of robust induction of glomerulosclerosis in mice: importance of genetic background","volume":"64","author":"Ma","year":"2003","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2014.235_bb0070","doi-asserted-by":"crossref","first-page":"23337","DOI":"10.1074\/jbc.M700194200","article-title":"Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition","volume":"282","author":"Zeisberg","year":"2007","journal-title":"J Biol Chem"},{"key":"10.1038\/ki.2014.235_bb0075","doi-asserted-by":"crossref","first-page":"F461","DOI":"10.1152\/ajprenal.90735.2008","article-title":"Reactive oxygen species\/oxidative stress contributes to progression of kidney fibrosis following transient ischemic injury in mice","volume":"297","author":"Kim","year":"2009","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1038\/ki.2014.235_bb0080","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1038\/nm1613","article-title":"Endothelial-to-mesenchymal transition contributes to cardiac fibrosis","volume":"13","author":"Zeisberg","year":"2007","journal-title":"Nat Med"},{"key":"10.1038\/ki.2014.235_bb0085","doi-asserted-by":"crossref","first-page":"2488","DOI":"10.1111\/j.1523-1755.2005.00358.x","article-title":"Antibodies against macrophages that overlap in specificity with fibroblasts","volume":"67","author":"Inoue","year":"2005","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2014.235_bb0090","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/BF03403533","article-title":"Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair","volume":"1","author":"Bucala","year":"1994","journal-title":"Mol Med"},{"key":"10.1038\/ki.2014.235_bb0095","doi-asserted-by":"crossref","first-page":"14098","DOI":"10.1073\/pnas.0511200103","article-title":"Secondary lymphoid tissue chemokine (SLC\/CCL21)\/CCR7 signaling regulates fibrocytes in renal fibrosis","volume":"103","author":"Sakai","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/ki.2014.235_bb0100","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1681\/ASN.2007060648","article-title":"Poly(ADP-ribose) polymerase-1 enhances transcription of the profibrotic CCN2 gene","volume":"19","author":"Okada","year":"2008","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2014.235_bb0105","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.2353\/ajpath.2006.060178","article-title":"A possible anti-inflammatory role of angiotensin II type 2 receptor in immune-mediated glomerulonephritis during type 1 receptor blockade","volume":"169","author":"Okada","year":"2006","journal-title":"Am J Pathol"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S008525381530017X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S008525381530017X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,6,25]],"date-time":"2022-06-25T07:38:36Z","timestamp":1656142716000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S008525381530017X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["S008525381530017X"],"URL":"https:\/\/doi.org\/10.1038\/ki.2014.235","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]}}}