{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T21:32:13Z","timestamp":1787002333690,"version":"build-2736575974"},"reference-count":53,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"vor","delay-in-days":1461,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["kidney-international.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2015,5]]},"DOI":"10.1038\/ki.2014.361","type":"journal-article","created":{"date-parts":[[2014,12,10]],"date-time":"2014-12-10T11:36:46Z","timestamp":1418211406000},"page":"1017-1029","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":121,"title":["Genome-wide association study of kidney function decline in individuals of European descent"],"prefix":"10.1016","volume":"87","author":[{"given":"Mathias","family":"Gorski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrienne","family":"Tin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maija","family":"Garnaas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gearoid M.","family":"McMahon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey Y.","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bamidele O.","family":"Tayo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristian","family":"Pattaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Teumer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel I.","family":"Chasman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Chalmers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavel","family":"Hamet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanne","family":"Tremblay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Woodward","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thor","family":"Aspelund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gudny","family":"Eiriksdottir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vilmundur","family":"Gudnason","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamara B.","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lenore J.","family":"Launer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert V.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Braxton D.","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey R.","family":"O'Connell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan R.","family":"Shuldiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josef","family":"Coresh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Man","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Freudenberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edith","family":"Hofer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reinhold","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth G.","family":"Holliday","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie Jin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian H.","family":"de Boer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S.","family":"Siscovick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoltan","family":"Kutalik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanguy","family":"Corre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Vollenweider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00e9rard","family":"Waeber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayanta","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter A.","family":"Kanetsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih-Jen","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Olden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariza","family":"de Andrade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth J.","family":"Atkinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon L.R.","family":"Kardia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen T.","family":"Turner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanette M.","family":"Stafford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingzhong","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongmei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Barlassina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele","family":"Cusi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Salvi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan A.","family":"Staessen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul M.","family":"Ridker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harald","family":"Grallert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christa","family":"Meisinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"M\u00fcller-Nurasyid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard K.","family":"Kr\u00e4mer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holly","family":"Kramer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvia E.","family":"Rosas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilja M.","family":"Nolte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenda W.","family":"Penninx","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harold","family":"Snieder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Fabiola Del Greco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre","family":"Franke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ute","family":"N\u00f6thlings","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Lieb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan J.L.","family":"Bakker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ron T.","family":"Gansevoort","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pim","family":"van der Harst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbas","family":"Dehghan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oscar H.","family":"Franco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Hofman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Rivadeneira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanaz","family":"Sedaghat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9 G.","family":"Uitterlinden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Coassin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margot","family":"Haun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Kollerits","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Kronenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Paulweber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Aumann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karlhans","family":"Endlich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike","family":"Pietzner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uwe","family":"V\u00f6lker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rainer","family":"Rettig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Chouraki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Helmer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Charles","family":"Lambert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Metzger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedicte","family":"Stengel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terho","family":"Lehtim\u00e4ki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leo-Pekka","family":"Lyytik\u00e4inen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olli","family":"Raitakari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afshin","family":"Parsa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murielle","family":"Bochud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iris M.","family":"Heid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfram","family":"Goessling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"K\u00f6ttgen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.H.","family":"Linda Kao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline S.","family":"Fox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten A.","family":"B\u00f6ger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/ki.2014.361_bb0010","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1001\/jama.298.17.2038","article-title":"Prevalence of chronic kidney disease in the United States","volume":"298","author":"Coresh","year":"2007","journal-title":"JAMA"},{"key":"10.1038\/ki.2014.361_bb0015","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0140-6736(05)17789-7","article-title":"Chronic kidney disease: the global challenge","volume":"365","author":"Meguid El Nahas","year":"2005","journal-title":"Lancet"},{"key":"10.1038\/ki.2014.361_bb0020","first-page":"1","article-title":"KDIGO Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease","volume":"3","author":"KDIGO","year":"2013","journal-title":"Kidney Int Suppl"},{"key":"10.1038\/ki.2014.361_bb0025","doi-asserted-by":"crossref","first-page":"2617","DOI":"10.1681\/ASN.2009010025","article-title":"Change in estimated GFR associates with coronary heart disease and mortality","volume":"20","author":"Matsushita","year":"2009","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2014.361_bb0030","doi-asserted-by":"crossref","first-page":"2212","DOI":"10.1001\/archinte.168.20.2212","article-title":"Rapid kidney function decline and mortality risk in older adults","volume":"168","author":"Rifkin","year":"2008","journal-title":"Arch Intern Med"},{"key":"10.1038\/ki.2014.361_bb0035","doi-asserted-by":"crossref","first-page":"2625","DOI":"10.1681\/ASN.2009050546","article-title":"Rapid decline of kidney function increases cardiovascular risk in the elderly","volume":"20","author":"Shlipak","year":"2009","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2014.361_bb0040","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1159\/000339289","article-title":"One-year change in kidney function is associated with an increased mortality risk","volume":"36","author":"Turin","year":"2012","journal-title":"Am J Nephrol"},{"key":"10.1038\/ki.2014.361_bb0045","doi-asserted-by":"crossref","first-page":"3835","DOI":"10.1093\/ndt\/gfs263","article-title":"Short-term change in kidney function and risk of end-stage renal disease","volume":"27","author":"Turin","year":"2012","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2014.361_bb0050","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1038\/ki.2012.443","article-title":"Change in the estimated glomerular filtration rate over time and risk of all-cause mortality","volume":"83","author":"Turin","year":"2013","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2014.361_bb0055","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1001\/jama.291.7.844","article-title":"Predictors of new-onset kidney disease in a community-based population","volume":"291","author":"Fox","year":"2004","journal-title":"JAMA"},{"key":"10.1038\/ki.2014.361_bb0060","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/j.1525-139X.2007.00282.x","article-title":"Familial clustering of chronic kidney disease","volume":"20","author":"Satko","year":"2007","journal-title":"Semin Dial"},{"key":"10.1038\/ki.2014.361_bb0065","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1038\/nrneph.2011.189","article-title":"Genome-wide association studies of chronic kidney disease: what have we learned?","volume":"8","author":"O'Seaghdha","year":"2012","journal-title":"Nat Rev Nephrol"},{"key":"10.1038\/ki.2014.361_bb0070","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/ng.566","article-title":"Genetic loci influencing kidney function and chronic kidney disease","volume":"42","author":"Chambers","year":"2010","journal-title":"Nat Genet"},{"key":"10.1038\/ki.2014.361_bb0075","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1038\/ng.377","article-title":"Multiple loci associated with indices of renal function and chronic kidney disease","volume":"41","author":"K\u00f6ttgen","year":"2009","journal-title":"Nat Genet"},{"key":"10.1038\/ki.2014.361_bb0080","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/ng.568","article-title":"New loci associated with kidney function and chronic kidney disease","volume":"42","author":"K\u00f6ttgen","year":"2010","journal-title":"Nat Genet"},{"key":"10.1038\/ki.2014.361_bb0085","doi-asserted-by":"crossref","first-page":"e1002584","DOI":"10.1371\/journal.pgen.1002584","article-title":"Genome-wide association and functional follow-up reveals new loci for kidney function","volume":"8","author":"Pattaro","year":"2012","journal-title":"PLoS Genet"},{"key":"10.1038\/ki.2014.361_bb0090","doi-asserted-by":"crossref","first-page":"e1002264","DOI":"10.1371\/journal.pgen.1002264","article-title":"Genetic association for renal traits among participants of African ancestry reveals new loci for renal function","volume":"7","author":"Liu","year":"2011","journal-title":"PLoS Genet"},{"key":"10.1038\/ki.2014.361_bb0095","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1038\/ng.2352","article-title":"Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations","volume":"44","author":"Okada","year":"2012","journal-title":"Nat Genet"},{"key":"10.1038\/ki.2014.361_bb0100","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1053\/j.ajkd.2008.05.030","article-title":"Mortality risks for all causes and cardiovascular diseases and reduced GFR in a middle-aged working population in Taiwan","volume":"52","author":"Cheng","year":"2008","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/ki.2014.361_bb0105","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1053\/j.ajkd.2011.12.009","article-title":"Longitudinal progression trajectory of GFR among patients with CKD","volume":"59","author":"Li","year":"2012","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/ki.2014.361_bb0110","doi-asserted-by":"crossref","first-page":"e1002292","DOI":"10.1371\/journal.pgen.1002292","article-title":"Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD","volume":"7","author":"B\u00f6ger","year":"2011","journal-title":"PLoS Genet"},{"key":"10.1038\/ki.2014.361_bb0115","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1152\/physiolgenomics.00015.2012","article-title":"Increased susceptibility to kidney injury by transfer of genomic segment from SHR onto Dahl S genetic background","volume":"44","author":"Regner","year":"2012","journal-title":"Physiol Genomics"},{"key":"10.1038\/ki.2014.361_bb0120","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1038\/ki.2011.474","article-title":"Integrin alpha1\/Akita double-knockout mice on a Balb\/c background develop advanced features of human diabetic nephropathy","volume":"81","author":"Yu","year":"2012","journal-title":"Kidney Int"},{"key":"10.1038\/ki.2014.361_bb0125","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1093\/aje\/kwp151","article-title":"Defining incident chronic kidney disease in the research setting: The ARIC Study","volume":"170","author":"Bash","year":"2009","journal-title":"Am J Epidemiol"},{"key":"10.1038\/ki.2014.361_bb0130","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.cell.2013.03.030","article-title":"Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease","volume":"153","author":"Zhang","year":"2013","journal-title":"Cell"},{"key":"10.1038\/ki.2014.361_bb0135","doi-asserted-by":"crossref","first-page":"e164","DOI":"10.1093\/nar\/gkq603","article-title":"ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data","volume":"38","author":"Wang","year":"2010","journal-title":"Nucleic Acids Res"},{"key":"10.1038\/ki.2014.361_bb0140","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.2215\/CJN.00070109","article-title":"Chronic Renal Insufficiency Cohort (CRIC) Study: baseline characteristics and associations with kidney function","volume":"4","author":"Lash","year":"2009","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1038\/ki.2014.361_bb0145","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/1471-2350-13-78","article-title":"UMOD as a susceptibility gene for end-stage renal disease","volume":"13","author":"Reznichenko","year":"2012","journal-title":"BMC Med Genet"},{"key":"10.1038\/ki.2014.361_bb0150","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1159\/000313927","article-title":"Progression of chronic kidney disease: Adrenergic genetic influence on glomerular filtration rate decline in hypertensive nephrosclerosis","volume":"32","author":"Chen","year":"2010","journal-title":"Am J Nephrol"},{"key":"10.1038\/ki.2014.361_bb0155","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1681\/ASN.2008111148","article-title":"Chromogranin A regulates renal function by triggering Weibel-Palade body exocytosis","volume":"20","author":"Chen","year":"2009","journal-title":"J Am Soc Nephrol"},{"key":"10.1038\/ki.2014.361_bb0160","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1159\/000320131","article-title":"Common charge-shift mutation Glu65Lys in K+ channel beta(1)-Subunit KCNMB1: pleiotropic consequences for glomerular filtration rate and progressive renal disease","volume":"32","author":"Chen","year":"2010","journal-title":"Am J Nephrol"},{"key":"10.1038\/ki.2014.361_bb0165","doi-asserted-by":"crossref","first-page":"3677","DOI":"10.1093\/ndt\/gfp471","article-title":"Adrenergic beta-1 receptor genetic variation predicts longitudinal rate of GFR decline in hypertensive nephrosclerosis","volume":"24","author":"Fung","year":"2009","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2014.361_bb0170","doi-asserted-by":"crossref","first-page":"e4787","DOI":"10.1371\/journal.pone.0004787","article-title":"Genetic polymorphisms and the risk of accelerated renal function decline in women","volume":"4","author":"Cooper Worobey","year":"2009","journal-title":"PLoS One"},{"key":"10.1038\/ki.2014.361_bb0175","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.ymgme.2008.03.014","article-title":"The PPAR gamma 2 Pro12Ala variant predicts ESRD and mortality in patients with type 1 diabetes and diabetic nephropathy","volume":"94","author":"Jorsal","year":"2008","journal-title":"Mol Genet Metab"},{"key":"10.1038\/ki.2014.361_bb0180","doi-asserted-by":"crossref","first-page":"e1002921","DOI":"10.1371\/journal.pgen.1002921","article-title":"New susceptibility loci associated with kidney disease in type 1 diabetes","volume":"8","author":"Sandholm","year":"2012","journal-title":"PLoS Genet"},{"key":"10.1038\/ki.2014.361_bb0185","doi-asserted-by":"crossref","first-page":"2544","DOI":"10.1093\/ndt\/gfq768","article-title":"Polymorphisms in the nonmuscle myosin heavy chain 9 gene (MYH9) are associated with the progression of IgA nephropathy in Chinese","volume":"26","author":"Cheng","year":"2011","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/ki.2014.361_bb0190","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s00109-009-0549-x","article-title":"Alpha- and beta-Adducin polymorphisms affect podocyte proteins and proteinuria in rodents and decline of renal function in human IgA nephropathy","volume":"88","author":"Ferrandi","year":"2010","journal-title":"J Mol Med (Berl)"},{"key":"10.1038\/ki.2014.361_bb0195","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1038\/nm.3384","article-title":"Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression","volume":"19","author":"Trudu","year":"2013","journal-title":"Nat Med"},{"key":"10.1038\/ki.2014.361_bb0200","doi-asserted-by":"crossref","first-page":"2915","DOI":"10.1073\/pnas.1019645108","article-title":"Rare copy number variations in congenital heart disease patients identify unique genes in left-right patterning","volume":"108","author":"Fakhro","year":"2011","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/ki.2014.361_bb0205","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1038\/nature12723","article-title":"The heterotaxy gene GALNT11 glycosylates Notch to orchestrate cilia type and laterality","volume":"504","author":"Boskovski","year":"2013","journal-title":"Nature"},{"key":"10.1038\/ki.2014.361_bb0210","doi-asserted-by":"crossref","first-page":"5252","DOI":"10.1073\/pnas.0900691106","article-title":"A mouse model for nonsyndromic deafness (DFNB12) links hearing loss to defects in tip links of mechanosensory hair cells","volume":"106","author":"Schwander","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/ki.2014.361_bb0215","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/83667","article-title":"Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1D","volume":"27","author":"Bolz","year":"2001","journal-title":"Nat Genet"},{"key":"10.1038\/ki.2014.361_bb0220","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1086\/316954","article-title":"Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of the novel cadherin-like gene CDH23","volume":"68","author":"Bork","year":"2001","journal-title":"Am J Hum Genet"},{"key":"10.1038\/ki.2014.361_bb0225","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/83660","article-title":"Mutations in Cdh23, encoding a new type of cadherin, cause stereocilia disorganization in waltzer, the mouse model for Usher syndrome type 1D","volume":"27","author":"Di Palma","year":"2001","journal-title":"Nat Genet"},{"key":"10.1038\/ki.2014.361_bb0230","doi-asserted-by":"crossref","first-page":"14946","DOI":"10.1073\/pnas.232579599","article-title":"The Usher syndrome proteins cadherin 23 and harmonin form a complex by means of PDZ-domain interactions","volume":"99","author":"Siemens","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/ki.2014.361_bb0235","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1038\/nbt1210-1248","article-title":"Towards a knowledge-based Human Protein Atlas","volume":"28","author":"Uhlen","year":"2010","journal-title":"Nat Biotechnol"},{"key":"10.1038\/ki.2014.361_bb0240","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1053\/ajkd.2002.32765","article-title":"Calibration and random variation of the serum creatinine assay as critical elements of using equations to estimate glomerular filtration rate","volume":"39","author":"Coresh","year":"2002","journal-title":"Am J Kidney Dis"},{"key":"10.1038\/ki.2014.361_bb0245","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1086\/301844","article-title":"Multipoint quantitative-trait linkage analysis in general pedigrees","volume":"62","author":"Almasy","year":"1998","journal-title":"Am J Hum Genet"},{"key":"10.1038\/ki.2014.361_bb0250","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1101\/gr.4413105","article-title":"The International HapMap Project Web site","volume":"15","author":"Thorisson","year":"2005","journal-title":"Genome Res"},{"key":"10.1038\/ki.2014.361_bb0255","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1093\/bioinformatics\/btr679","article-title":"GWAtoolbox: an R package for fast quality control and handling of genome-wide association studies meta-analysis data","volume":"28","author":"Fuchsberger","year":"2012","journal-title":"Bioinformatics"},{"key":"10.1038\/ki.2014.361_bb0260","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1111\/j.0006-341X.1999.00997.x","article-title":"Genomic control for association studies","volume":"55","author":"Devlin","year":"1999","journal-title":"Biometrics"},{"key":"10.1038\/ki.2014.361_bb0265","doi-asserted-by":"crossref","first-page":"4655","DOI":"10.1242\/dev.125.23.4655","article-title":"Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function","volume":"125","author":"Drummond","year":"1998","journal-title":"Development"},{"key":"10.1038\/ki.2014.361_bb0270","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.ydbio.2005.06.038","article-title":"Organization of the pronephric filtration apparatus in zebrafish requires Nephrin, Podocin and the FERM domain protein Mosaic eyes","volume":"285","author":"Kramer-Zucker","year":"2005","journal-title":"Dev Biol"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815300909?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253815300909?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T04:57:48Z","timestamp":1668574668000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253815300909"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5]]},"references-count":53,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["S0085253815300909"],"URL":"https:\/\/doi.org\/10.1038\/ki.2014.361","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2015,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Genome-wide association study of kidney function decline in individuals of European descent","name":"articletitle","label":"Article Title"},{"value":"Kidney International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/ki.2014.361","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}