{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T06:16:09Z","timestamp":1773382569516,"version":"3.50.1"},"reference-count":60,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T00:00:00Z","timestamp":1673395200000},"content-version":"vor","delay-in-days":4789,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["li.uscap.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Laboratory Investigation"],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1038\/labinvest.2009.105","type":"journal-article","created":{"date-parts":[[2009,10,12]],"date-time":"2009-10-12T10:33:26Z","timestamp":1255343606000},"page":"1374-1386","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Compensatory role of inducible annexin A2 for impaired biliary epithelial anion-exchange activity of inflammatory cholangiopathy"],"prefix":"10.1016","volume":"89","author":[{"given":"Osamu","family":"Kido","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Fukushima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiyuki","family":"Ueno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas M","family":"Jefferson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tooru","family":"Shimosegawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1038\/labinvest.2009.105_bib1","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1136\/jcp.2004.023507","article-title":"Interferon gamma accelerates NF-kappaB activation of biliary epithelial cells induced by Toll-like receptor and ligand interaction","volume":"59","author":"Harada","year":"2006","journal-title":"J Clin Pathol"},{"key":"10.1038\/labinvest.2009.105_bib2","first-page":"89","article-title":"Increased expression of interleukin-6 and tumor necrosis factor-alpha in pathologic biliary epithelial cells: in situ and culture study","volume":"78","author":"Yasoshima","year":"1998","journal-title":"Lab Invest"},{"key":"10.1038\/labinvest.2009.105_bib3","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1055\/s-2007-1007189","article-title":"Cytokines in primary biliary cirrhosis","volume":"17","author":"Berg","year":"1997","journal-title":"Semin Liver Dis"},{"key":"10.1038\/labinvest.2009.105_bib4","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1002\/hep.510250402","article-title":"In situ nucleic acid hybridization of cytokines in primary biliary cirrhosis: predominance of the Th1 subset","volume":"25","author":"Harada","year":"1997","journal-title":"Hepatology"},{"key":"10.1038\/labinvest.2009.105_bib5","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1053\/gast.2001.25516","article-title":"Proinflammatory cytokines inhibit secretion in rat bile duct epithelium","volume":"121","author":"Spirli","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1038\/labinvest.2009.105_bib6","doi-asserted-by":"crossref","first-page":"3242","DOI":"10.1093\/emboj\/cdg321","article-title":"Annexin II regulates multivesicular endosome biogenesis in the degradation pathway of animal cells","volume":"22","author":"Mayran","year":"2003","journal-title":"EMBO J"},{"key":"10.1038\/labinvest.2009.105_bib7","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1038\/nrm1360","article-title":"The biogenesis of multivesicular endosomes","volume":"5","author":"Gruenberg","year":"2004","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1038\/labinvest.2009.105_bib8","doi-asserted-by":"crossref","first-page":"4896","DOI":"10.1091\/mbc.e03-06-0387","article-title":"The annexin 2\/S100A10 complex controls the distribution of transferrin receptor-containing recycling endosomes","volume":"14","author":"Zobiack","year":"2003","journal-title":"Mol Biol Cell"},{"key":"10.1038\/labinvest.2009.105_bib9","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1091\/mbc.8.3.533","article-title":"Specific release of membrane-bound annexin II and cortical cytoskeletal elements by sequestration of membrane cholesterol","volume":"8","author":"Harder","year":"1997","journal-title":"Mol Biol Cell"},{"key":"10.1038\/labinvest.2009.105_bib10","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1078\/0171-9335-00184","article-title":"Association of annexin 2 with recycling endosomes requires either calcium- or cholesterol-stabilized membrane domains","volume":"80","author":"Zeuschner","year":"2001","journal-title":"Eur J Cell Biol"},{"key":"10.1038\/labinvest.2009.105_bib11","doi-asserted-by":"crossref","first-page":"2631","DOI":"10.1242\/jcs.01245","article-title":"Annexins\u2014unique membrane binding proteins with diverse functions","volume":"117","author":"Rescher","year":"2004","journal-title":"J Cell Sci"},{"key":"10.1038\/labinvest.2009.105_bib12","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1186\/gb-2004-5-4-219","article-title":"The annexins","volume":"5","author":"Moss","year":"2004","journal-title":"Genome Biol"},{"key":"10.1038\/labinvest.2009.105_bib13","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.jhep.2007.12.015","article-title":"Direct effects of alcohol on hepatic fibrinolytic balance: implications for alcoholic liver disease","volume":"48","author":"Seth","year":"2008","journal-title":"J Hepatol"},{"key":"10.1038\/labinvest.2009.105_bib14","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1113\/expphysiol.2005.031765","article-title":"Molecular physiology of SLC4 anion exchangers","volume":"91","author":"Alper","year":"2006","journal-title":"Exp Physiol"},{"key":"10.1038\/labinvest.2009.105_bib15","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1002\/hep.21042","article-title":"Bicarbonate-rich choleresis induced by secretin in normal rat is taurocholate-dependent and involves AE2 anion exchanger","volume":"43","author":"Banales","year":"2006","journal-title":"Hepatology"},{"key":"10.1038\/labinvest.2009.105_bib16","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1002\/hep.510250104","article-title":"Decreased anion exchanger 2 immunoreactivity in the liver of patients with primary biliary cirrhosis","volume":"25","author":"Medina","year":"1997","journal-title":"Hepatology"},{"key":"10.1038\/labinvest.2009.105_bib17","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1053\/j.gastro.2008.02.020","article-title":"Ae2a, b-deficient mice develop antimitochondrial antibodies and other features resembling primary biliary cirrhosis","volume":"134","author":"Salas","year":"2008","journal-title":"Gastroenterology"},{"key":"10.1038\/labinvest.2009.105_bib18","first-page":"G1060","article-title":"Regulation of intracellular pH by immortalized human intrahepatic biliary epithelial cell lines","volume":"266","author":"Grubman","year":"1994","journal-title":"Am J Physiol"},{"key":"10.1038\/labinvest.2009.105_bib19","first-page":"1257","article-title":"Primary biliary cirrhosis","volume":"60","author":"Scheuer","year":"1967","journal-title":"Proc R Soc Med"},{"key":"10.1038\/labinvest.2009.105_bib20","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1002\/jmv.20363","article-title":"High prevalence of hepatitis delta virus infection detectable by enzyme immunoassay among apparently healthy individuals in Mongolia","volume":"76","author":"Inoue","year":"2005","journal-title":"J Med Virol"},{"key":"10.1038\/labinvest.2009.105_bib21","first-page":"G1236","article-title":"Functional polarity of Na+\/H+ and Cl\u2212\/HCO3\u2212 exchangers in a rat cholangiocyte cell line","volume":"275","author":"Spirli","year":"1998","journal-title":"Am J Physiol"},{"key":"10.1038\/labinvest.2009.105_bib22","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1002\/hep.1840190613","article-title":"Immunohistochemical detection of chloride\/bicarbonate anion exchangers in human liver","volume":"19","author":"Martinez-Anso","year":"1994","journal-title":"Hepatology"},{"key":"10.1038\/labinvest.2009.105_bib23","doi-asserted-by":"crossref","first-page":"C1485","DOI":"10.1152\/ajpcell.00447.2006","article-title":"Regulation of anion exchanger Slc26a6 by protein kinase C","volume":"292","author":"Hassan","year":"2007","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1038\/labinvest.2009.105_bib24","doi-asserted-by":"crossref","first-page":"3016","DOI":"10.1101\/gad.1262504","article-title":"The Drosha\u2013DGCR8 complex in primary microRNA processing","volume":"18","author":"Han","year":"2004","journal-title":"Genes Dev"},{"key":"10.1038\/labinvest.2009.105_bib25","doi-asserted-by":"crossref","first-page":"24245","DOI":"10.1016\/S0021-9258(18)54219-8","article-title":"Interferon induces tryptophanyl-tRNA synthetase expression in human fibroblasts","volume":"266","author":"Rubin","year":"1991","journal-title":"J Biol Chem"},{"key":"10.1038\/labinvest.2009.105_bib26","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S0014-5793(98)00916-8","article-title":"Identification, functional expression and chromosomal localisation of a sustained human proton-gated cation channel","volume":"433","author":"de Weille","year":"1998","journal-title":"FEBS Lett"},{"key":"10.1038\/labinvest.2009.105_bib27","doi-asserted-by":"crossref","first-page":"3336","DOI":"10.1128\/MCB.15.6.3336","article-title":"Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis","volume":"15","author":"Quelle","year":"1995","journal-title":"Mol Cell Biol"},{"key":"10.1038\/labinvest.2009.105_bib28","first-page":"155","article-title":"Molecular cloning and characterization of human WINS1 and mouse Wins2, homologous to Drosophila segment polarity gene Lines (Lin)","volume":"10","author":"Katoh","year":"2002","journal-title":"Int J Mol Med"},{"key":"10.1038\/labinvest.2009.105_bib29","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1111\/j.0105-2896.2005.00225.x","article-title":"Bruton\u2019s tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling","volume":"203","author":"Lindvall","year":"2005","journal-title":"Immunol Rev"},{"key":"10.1038\/labinvest.2009.105_bib30","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1006\/dbio.2002.0764","article-title":"Developmental expression and biochemical characterization of Emu family members","volume":"249","author":"Leimeister","year":"2002","journal-title":"Dev Biol"},{"key":"10.1038\/labinvest.2009.105_bib31","doi-asserted-by":"crossref","first-page":"11396","DOI":"10.1074\/jbc.M707549200","article-title":"Identification of chondroitin sulfate glucuronyltransferase as chondroitin synthase-3 involved in chondroitin polymerization: chondroitin polymerization is achieved by multiple enzyme complexes consisting of chondroitin synthase family members","volume":"283","author":"Izumikawa","year":"2008","journal-title":"J Biol Chem"},{"key":"10.1038\/labinvest.2009.105_bib32","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1006\/excr.1995.1406","article-title":"Cyclin I: a new cyclin encoded by a gene isolated from human brain","volume":"221","author":"Nakamura","year":"1995","journal-title":"Exp Cell Res"},{"key":"10.1038\/labinvest.2009.105_bib33","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1006\/geno.1998.5562","article-title":"Genomic cloning, molecular characterization, and functional analysis of human CLCA1, the first human member of the family of Ca2+-activated Cl\u2212 channel proteins","volume":"54","author":"Gruber","year":"1998","journal-title":"Genomics"},{"key":"10.1038\/labinvest.2009.105_bib34","doi-asserted-by":"crossref","first-page":"28780","DOI":"10.1074\/jbc.270.48.28780","article-title":"Heterogeneous nuclear ribonucleoproteins H, H\u2019, and F are members of a ubiquitously expressed subfamily of related but distinct proteins encoded by genes mapping to different chromosomes","volume":"270","author":"Honore","year":"1995","journal-title":"J Biol Chem"},{"key":"10.1038\/labinvest.2009.105_bib35","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.1600-065X.1998.tb01185.x","article-title":"The C-type lectin superfamily in the immune system","volume":"163","author":"Weis","year":"1998","journal-title":"Immunol Rev"},{"key":"10.1038\/labinvest.2009.105_bib36","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1002\/(SICI)1098-1004(1997)10:4<290::AID-HUMU4>3.0.CO;2-L","article-title":"Evidence for founder effect of the Glu104Asp substitution and identification of new mutations in triosephosphate isomerase deficiency","volume":"10","author":"Arya","year":"1997","journal-title":"Hum Mutat"},{"key":"10.1038\/labinvest.2009.105_bib37","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1038\/sj.mp.4000688","article-title":"Genomic structure and novel variants of myo-inositol monophosphatase 2 (IMPA2)","volume":"5","author":"Yoshikawa","year":"2000","journal-title":"Mol Psychiatry"},{"key":"10.1038\/labinvest.2009.105_bib38","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/0092-8674(86)90693-8","article-title":"Speculations on the functions of the major heat shock and glucose-regulated proteins","volume":"46","author":"Pelham","year":"1986","journal-title":"Cell"},{"key":"10.1038\/labinvest.2009.105_bib39","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0378-1119(97)00417-4","article-title":"Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene","volume":"200","author":"Neesen","year":"1997","journal-title":"Gene"},{"key":"10.1038\/labinvest.2009.105_bib40","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1042\/BC20040089","article-title":"Cytoskeletal and motor proteins facilitate trafficking of AQP1-containing vesicles in cholangiocytes","volume":"98","author":"Tietz","year":"2006","journal-title":"Biol Cell"},{"key":"10.1038\/labinvest.2009.105_bib41","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1038\/24884","article-title":"Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP","volume":"396","author":"de Rooij","year":"1998","journal-title":"Nature"},{"key":"10.1038\/labinvest.2009.105_bib42","doi-asserted-by":"crossref","first-page":"30","DOI":"10.2741\/1503","article-title":"Alpha-enolase plasminogen receptor in myogenesis","volume":"10","author":"Lopez-Alemany","year":"2005","journal-title":"Front Biosci"},{"key":"10.1038\/labinvest.2009.105_bib43","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/S0168-8278(97)80251-6","article-title":"Identification of an autoantibody against alpha-enolase in primary biliary cirrhosis","volume":"26","author":"Akisawa","year":"1997","journal-title":"J Hepatol"},{"key":"10.1038\/labinvest.2009.105_bib44","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.cardiores.2004.11.010","article-title":"Annexins and Ca2+ handling in the heart","volume":"65","author":"Camors","year":"2005","journal-title":"Cardiovasc Res"},{"key":"10.1038\/labinvest.2009.105_bib45","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1038\/nrm1661","article-title":"Annexins: linking Ca2+ signalling to membrane dynamics","volume":"6","author":"Gerke","year":"2005","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1038\/labinvest.2009.105_bib46","doi-asserted-by":"crossref","first-page":"21191","DOI":"10.1016\/S0021-9258(17)31947-6","article-title":"An endothelial cell receptor for plasminogen\/tissue plasminogen activator. I. Identity with annexin II","volume":"269","author":"Hajjar","year":"1994","journal-title":"J Biol Chem"},{"key":"10.1038\/labinvest.2009.105_bib47","doi-asserted-by":"crossref","first-page":"4790","DOI":"10.1074\/jbc.273.8.4790","article-title":"The role of annexin II tetramer in the activation of plasminogen","volume":"273","author":"Kassam","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1038\/labinvest.2009.105_bib48","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0092-8674(86)90736-1","article-title":"Two human 35 kDa inhibitors of phospholipase A2 are related to substrates of pp60v-src and of the epidermal growth factor receptor\/kinase","volume":"46","author":"Huang","year":"1986","journal-title":"Cell"},{"key":"10.1038\/labinvest.2009.105_bib49","doi-asserted-by":"crossref","first-page":"d341","DOI":"10.2741\/kim","article-title":"Annexin II: a plasminogen\u2013plasminogen activator co-receptor","volume":"7","author":"Kim","year":"2002","journal-title":"Front Biosci"},{"key":"10.1038\/labinvest.2009.105_bib50","doi-asserted-by":"crossref","first-page":"30631","DOI":"10.1074\/jbc.271.48.30631","article-title":"Annexin II modulates volume-activated chloride currents in vascular endothelial cells","volume":"271","author":"Nilius","year":"1996","journal-title":"J Biol Chem"},{"key":"10.1038\/labinvest.2009.105_bib51","doi-asserted-by":"crossref","first-page":"3388","DOI":"10.1091\/mbc.e07-02-0126","article-title":"The formation of the cAMP\/protein kinase A-dependent annexin 2\u2013S100A10 complex with cystic fibrosis conductance regulator protein (CFTR) regulates CFTR channel function","volume":"18","author":"Borthwick","year":"2007","journal-title":"Mol Biol Cell"},{"key":"10.1038\/labinvest.2009.105_bib52","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/j.bbamem.2007.03.026","article-title":"Use of cyclodextrins to manipulate plasma membrane cholesterol content: evidence, misconceptions and control strategies","volume":"1768","author":"Zidovetzki","year":"2007","journal-title":"Biochim Biophys Acta"},{"key":"10.1038\/labinvest.2009.105_bib53","doi-asserted-by":"crossref","first-page":"3496","DOI":"10.3748\/wjg.v12.i22.3496","article-title":"Cholangiocyte anion exchange and biliary bicarbonate excretion","volume":"12","author":"Banales","year":"2006","journal-title":"World J Gastroenterol"},{"key":"10.1038\/labinvest.2009.105_bib54","doi-asserted-by":"crossref","first-page":"2779","DOI":"10.1113\/jphysiol.2008.153015","article-title":"Fluid flow induces mechanosensitive ATP release, calcium signalling and Cl\u2212 transport in biliary epithelial cells through a PKCzeta-dependent pathway","volume":"586","author":"Woo","year":"2008","journal-title":"J Physiol"},{"key":"10.1038\/labinvest.2009.105_bib55","doi-asserted-by":"crossref","first-page":"C1611","DOI":"10.1152\/ajpcell.1996.270.6.C1611","article-title":"Apical and basolateral ATP stimulates tracheal epithelial chloride secretion via multiple purinergic receptors","volume":"270","author":"Hwang","year":"1996","journal-title":"Am J Physiol"},{"key":"10.1038\/labinvest.2009.105_bib56","first-page":"403","article-title":"Characterization of a swelling-activated anion conductance in homozygous typing cell hepatoma cells","volume":"25","author":"Bodily","year":"1997","journal-title":"Hepatology"},{"key":"10.1038\/labinvest.2009.105_bib57","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.1107\/S0907444999009981","article-title":"Crystallization and preliminary X-ray diffraction studies of hyperthermostable glutamate dehydrogenase from Thermococcus profundus","volume":"55","author":"Higuchi","year":"1999","journal-title":"Acta Crystallogr D Biol Crystallogr"},{"key":"10.1038\/labinvest.2009.105_bib58","doi-asserted-by":"crossref","first-page":"25976","DOI":"10.1016\/S0021-9258(18)35704-1","article-title":"Phosphorylation of annexin II tetramer by protein kinase C inhibits aggregation of lipid vesicles by the protein","volume":"267","author":"Johnstone","year":"1992","journal-title":"J Biol Chem"},{"key":"10.1038\/labinvest.2009.105_bib59","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1159\/000095180","article-title":"P2Y receptors activate MAPK\/ERK through a pathway involving PI3K\/PDK1\/PKC-zeta in human vein endothelial cells","volume":"18","author":"Montiel","year":"2006","journal-title":"Cell Physiol Biochem"},{"key":"10.1038\/labinvest.2009.105_bib60","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1152\/physrev.00030.2001","article-title":"Annexins: from structure to function","volume":"82","author":"Gerke","year":"2002","journal-title":"Physiol Rev"}],"container-title":["Laboratory Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/labinvest2009105.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/labinvest2009105","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002368372202565X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002368372202565X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/labinvest2009105.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T19:49:25Z","timestamp":1758397765000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002368372202565X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":60,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["S002368372202565X"],"URL":"https:\/\/doi.org\/10.1038\/labinvest.2009.105","relation":{},"ISSN":["0023-6837"],"issn-type":[{"value":"0023-6837","type":"print"}],"subject":[],"published":{"date-parts":[[2009,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Compensatory role of inducible annexin A2 for impaired biliary epithelial anion-exchange activity of inflammatory cholangiopathy","name":"articletitle","label":"Article Title"},{"value":"Laboratory Investigation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/labinvest.2009.105","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2009 United States & Canadian Academy of Pathology.","name":"copyright","label":"Copyright"}]}}