{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T10:26:20Z","timestamp":1774952780149,"version":"3.50.1"},"reference-count":21,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T00:00:00Z","timestamp":1673395200000},"content-version":"vor","delay-in-days":4089,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["li.uscap.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Laboratory Investigation"],"published-print":{"date-parts":[[2011,11]]},"DOI":"10.1038\/labinvest.2011.121","type":"journal-article","created":{"date-parts":[[2011,8,24]],"date-time":"2011-08-24T06:53:15Z","timestamp":1314168795000},"page":"1643-1651","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Regressed lymphatic vessels develop during corneal repair"],"prefix":"10.1016","volume":"91","author":[{"given":"Philip M","family":"Kelley","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria M","family":"Steele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard M","family":"Tempero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1038\/labinvest.2011.121_bib1","doi-asserted-by":"crossref","first-page":"535","DOI":"10.4049\/jimmunol.0903180","article-title":"Cutting edge: lymphatic vessels, not blood vessels, primarily mediate immune rejections after transplantation","volume":"184","author":"Dietrich","year":"2010","journal-title":"J Immunol"},{"key":"10.1038\/labinvest.2011.121_bib2","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1084\/jem.20091385","article-title":"VEGF-A expression by HSV-1-infected cells drives corneal lymphangiogenesis","volume":"207","author":"Wuest","year":"2010","journal-title":"J Exp Med"},{"key":"10.1038\/labinvest.2011.121_bib3","doi-asserted-by":"crossref","first-page":"3958","DOI":"10.1073\/pnas.0813368106","article-title":"Abnormal lymphangiogenesis in idiopathic pulmonary fibrosis with insights into cellular and molecular mechanisms","volume":"106","author":"El-Chemaly","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/labinvest.2011.121_bib4","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1038\/ki.2008.661","article-title":"Lymphatic vessels develop during tubulointerstitial fibrosis","volume":"75","author":"Sakamoto","year":"2009","journal-title":"Kidney Int"},{"key":"10.1038\/labinvest.2011.121_bib5","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1172\/JCI200522037","article-title":"Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation","volume":"115","author":"Baluk","year":"2005","journal-title":"J Clin Invest"},{"key":"10.1038\/labinvest.2011.121_bib6","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.2353\/ajpath.2010.090909","article-title":"Steroid-resistant lymphatic remodeling in chronically inflamed mouse airways","volume":"176","author":"Yao","year":"2010","journal-title":"Am J Pathol"},{"key":"10.1038\/labinvest.2011.121_bib7","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1136\/bjo.2008.145128","article-title":"Transient postoperative vascular endothelial growth factor (VEGF)-neutralisation improves graft survival in corneas with partly regressed inflammatory neovascularisation 27","volume":"93","author":"Bachmann","year":"2009","journal-title":"Br J Ophthalmol"},{"key":"10.1038\/labinvest.2011.121_bib8","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1097\/01.ico.0000183485.85636.ff","article-title":"Time course of angiogenesis and lymphangiogenesis after brief corneal inflammation","volume":"25","author":"Cursiefen","year":"2006","journal-title":"Cornea"},{"key":"10.1038\/labinvest.2011.121_bib9","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1084\/jem.20062596","article-title":"Functionally specialized junctions between endothelial cells of lymphatic vessels","volume":"204","author":"Baluk","year":"2007","journal-title":"J Exp Med"},{"key":"10.1038\/labinvest.2011.121_bib10","doi-asserted-by":"crossref","first-page":"2763","DOI":"10.1084\/jem.20051759","article-title":"An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium","volume":"203","author":"Johnson","year":"2006","journal-title":"J Exp Med"},{"key":"10.1038\/labinvest.2011.121_bib11","doi-asserted-by":"crossref","first-page":"2925","DOI":"10.1084\/jem.20091739","article-title":"Preformed portals facilitate dendritic cell entry into afferent lymphatic vessels","volume":"206","author":"Pflicke","year":"2009","journal-title":"J Exp Med"},{"key":"10.1038\/labinvest.2011.121_bib12","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1167\/iovs.10-5404","article-title":"Spontaneous lymphatic vessel formation and regression in the murine cornea","volume":"52","author":"Zhang","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1038\/labinvest.2011.121_bib13","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.4161\/cc.5.18.3210","article-title":"New insights regarding vessel regression","volume":"5","author":"Im","year":"2006","journal-title":"Cell Cycle"},{"key":"10.1038\/labinvest.2011.121_bib14","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.cell.2010.01.045","article-title":"Lymphangiogenesis: molecular mechanisms and future promise","volume":"140","author":"Tammela","year":"2010","journal-title":"Cell"},{"key":"10.1038\/labinvest.2011.121_bib15","doi-asserted-by":"crossref","first-page":"4571","DOI":"10.1182\/blood-2007-10-120337","article-title":"Inhibition of endogenous TGF-beta signaling enhances lymphangiogenesis","volume":"111","author":"Oka","year":"2008","journal-title":"Blood"},{"key":"10.1038\/labinvest.2011.121_bib16","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.matbio.2011.03.001","article-title":"beta1 integrin regulates MMP-10 dependant tubulogenesis in human lymphatic endothelial cells","volume":"30","author":"Steele","year":"2011","journal-title":"Matrix Biol"},{"key":"10.1038\/labinvest.2011.121_bib17","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.immuni.2008.08.006","article-title":"Mechanisms and consequences of dendritic cell migration","volume":"29","author":"Alvarez","year":"2008","journal-title":"Immunity"},{"key":"10.1038\/labinvest.2011.121_bib18","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.imbio.2008.07.025","article-title":"The lymph vessel network in mouse skin visualised with antibodies against the hyaluronan receptor LYVE-1","volume":"213","author":"Tripp","year":"2008","journal-title":"Immunobiology"},{"key":"10.1038\/labinvest.2011.121_bib19","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1038\/nri1670","article-title":"Dendritic-cell trafficking to lymph nodes through lymphatic vessels","volume":"5","author":"Randolph","year":"2005","journal-title":"Nat Rev Immunol"},{"key":"10.1038\/labinvest.2011.121_bib20","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1172\/JCI23874","article-title":"Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages","volume":"115","author":"Maruyama","year":"2005","journal-title":"J Clin Invest"},{"key":"10.1038\/labinvest.2011.121_bib21","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.ceb.2009.05.003","article-title":"Mechanical modes of \u2018amoeboid' cell migration","volume":"21","author":"Lammermann","year":"2009","journal-title":"Curr Opin Cell Biol"}],"container-title":["Laboratory Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/labinvest2011121.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/labinvest2011121","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0023683722032536?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0023683722032536?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/labinvest2011121.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T19:56:40Z","timestamp":1758398200000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0023683722032536"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11]]},"references-count":21,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["S0023683722032536"],"URL":"https:\/\/doi.org\/10.1038\/labinvest.2011.121","relation":{},"ISSN":["0023-6837"],"issn-type":[{"value":"0023-6837","type":"print"}],"subject":[],"published":{"date-parts":[[2011,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Regressed lymphatic vessels develop during corneal repair","name":"articletitle","label":"Article Title"},{"value":"Laboratory Investigation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/labinvest.2011.121","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2011 United States & Canadian Academy of Pathology.","name":"copyright","label":"Copyright"}]}}