{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T05:06:14Z","timestamp":1790658374984,"version":"4.1.0"},"reference-count":62,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T00:00:00Z","timestamp":1673395200000},"content-version":"vor","delay-in-days":3116,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["li.uscap.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Laboratory Investigation"],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.1038\/labinvest.2014.66","type":"journal-article","created":{"date-parts":[[2014,5,5]],"date-time":"2014-05-05T08:42:10Z","timestamp":1399279330000},"page":"752-765","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Neuropilin 1 expression correlates with differentiation status of epidermal cells and cutaneous squamous cell carcinomas"],"prefix":"10.1016","volume":"94","author":[{"given":"Shokoufeh","family":"Shahrabi-Farahani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lili","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernadette MM","family":"Zwaans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeans M","family":"Santana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akio","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seiji","family":"Takashima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Kreuter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leigh","family":"Coultas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia A","family":"D'Amore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey M","family":"Arbeit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars A","family":"Akslen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane R","family":"Bielenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/labinvest.2014.66_bib1","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/S0092-8674(00)81402-6","article-title":"Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor","volume":"92","author":"Soker","year":"1998","journal-title":"Cell"},{"key":"10.1038\/labinvest.2014.66_bib2","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/s10555-007-9097-4","article-title":"Targeting endothelial and tumor cells with semaphorins","volume":"26","author":"Bielenberg","year":"2007","journal-title":"Cancer Metastasis Rev"},{"key":"10.1038\/labinvest.2014.66_bib3","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1006\/geno.1999.5790","article-title":"Human neuropilin-1 and neuropilin-2 map to 10p12 and 2q34, respectively","volume":"57","author":"Rossignol","year":"1999","journal-title":"Genomics"},{"key":"10.1038\/labinvest.2014.66_bib4","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1006\/geno.2000.6381","article-title":"Genomic organization of human neuropilin-1 and neuropilin-2 genes: identification and distribution of splice variants and soluble isoforms","volume":"70","author":"Rossignol","year":"2000","journal-title":"Genomics"},{"key":"10.1038\/labinvest.2014.66_bib5","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0896-6273(00)80371-2","article-title":"Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III","volume":"19","author":"Chen","year":"1997","journal-title":"Neuron"},{"key":"10.1038\/labinvest.2014.66_bib6","series-title":"Endothelial Biomedicine","first-page":"327","article-title":"Neuropilins, receptors central to angiogenesis and neuronal guidance","author":"Bielenberg","year":"2007"},{"key":"10.1038\/labinvest.2014.66_bib7","doi-asserted-by":"crossref","first-page":"6763","DOI":"10.1158\/1078-0432.CCR-09-1810","article-title":"Role of class 3 semaphorins and their receptors in tumor growth and angiogenesis","volume":"15","author":"Gaur","year":"2009","journal-title":"Clin Cancer Res"},{"key":"10.1038\/labinvest.2014.66_bib8","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s10456-008-9097-1","article-title":"Neuropilin structure governs VEGF and semaphorin binding and regulates angiogenesis","volume":"11","author":"Geretti","year":"2008","journal-title":"Angiogenesis"},{"key":"10.1038\/labinvest.2014.66_bib9","doi-asserted-by":"crossref","first-page":"24818","DOI":"10.1074\/jbc.M200730200","article-title":"Neuropilin-1 binds vascular endothelial growth factor 165, placenta growth factor-2, and heparin via its b1b2 domain","volume":"277","author":"Mamluk","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1038\/labinvest.2014.66_bib10","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1096\/fj.05-5646com","article-title":"Functional interaction of VEGF-C and VEGF-D with neuropilin receptors","volume":"20","author":"Karpanen","year":"2006","journal-title":"FASEB J"},{"key":"10.1038\/labinvest.2014.66_bib11","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1002\/1097-4695(200008)44:2<219::AID-NEU11>3.0.CO;2-W","article-title":"Molecular basis of semaphorin-mediated axon guidance","volume":"44","author":"Nakamura","year":"2000","journal-title":"J Neurobiol"},{"key":"10.1038\/labinvest.2014.66_bib12","doi-asserted-by":"crossref","first-page":"RE1","DOI":"10.1126\/stke.2002.119.re1","article-title":"Knowing how to navigate: mechanisms of semaphorin signaling in the nervous system","volume":"2002","author":"He","year":"2002","journal-title":"Sci STKE"},{"key":"10.1038\/labinvest.2014.66_bib13","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0925-4773(01)00518-4","article-title":"Differential expression of neuropilin-1 and neuropilin-2 in arteries and veins","volume":"109","author":"Herzog","year":"2001","journal-title":"Mech Dev"},{"key":"10.1038\/labinvest.2014.66_bib14","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1242\/dev.00929","article-title":"Flow regulates arterial-venous differentiation in the chick embryo yolk sac","volume":"131","author":"le Noble","year":"2004","journal-title":"Development"},{"key":"10.1038\/labinvest.2014.66_bib15","doi-asserted-by":"crossref","first-page":"4797","DOI":"10.1242\/dev.129.20.4797","article-title":"Abnormal lymphatic vessel development in neuropilin 2 mutant mice","volume":"129","author":"Yuan","year":"2002","journal-title":"Development"},{"key":"10.1038\/labinvest.2014.66_bib16","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/j.1365-2613.2012.00810.x","article-title":"Neuropilins: expression and roles in the epithelium","volume":"93","author":"Wild","year":"2012","journal-title":"Int J Exp Pathol"},{"key":"10.1038\/labinvest.2014.66_bib17","doi-asserted-by":"crossref","first-page":"2573","DOI":"10.1073\/pnas.040337597","article-title":"Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: In vivo expression and antitumor activity","volume":"97","author":"Gagnon","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/labinvest.2014.66_bib18","doi-asserted-by":"crossref","first-page":"2721","DOI":"10.1074\/jbc.M507860200","article-title":"Neuron restrictive silencer factor NRSF\/REST is a transcriptional repressor of neuropilin-1 and diminishes the ability of semaphorin 3A to inhibit keratinocyte migration","volume":"281","author":"Kurschat","year":"2006","journal-title":"J Biol Chem"},{"key":"10.1038\/labinvest.2014.66_bib19","doi-asserted-by":"crossref","first-page":"4895","DOI":"10.1242\/dev.126.21.4895","article-title":"A requirement for neuropilin-1 in embryonic vessel formation","volume":"126","author":"Kawasaki","year":"1999","journal-title":"Development"},{"key":"10.1038\/labinvest.2014.66_bib20","doi-asserted-by":"crossref","first-page":"e50944","DOI":"10.1371\/journal.pone.0050944","article-title":"Epidermal expression of neuropilin 1 protects murine keratinocytes from UVB-induced apoptosis","volume":"7","author":"Riese","year":"2012","journal-title":"PloS One"},{"key":"10.1038\/labinvest.2014.66_bib21","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s10456-005-9009-6","article-title":"Soluble neuropilin targeted to the skin inhibits vascular permeability","volume":"8","author":"Mamluk","year":"2005","journal-title":"Angiogenesis"},{"key":"10.1038\/labinvest.2014.66_bib22","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1084\/jem.180.3.1141","article-title":"Overexpression of vascular permeability factor\/vascular endothelial growth factor and its receptors in psoriasis","volume":"180","author":"Detmar","year":"1994","journal-title":"J Exp Med"},{"key":"10.1038\/labinvest.2014.66_bib23","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1365-2133.2005.06368.x","article-title":"Ultraviolet B irradiation of human skin induces an angiogenic switch that is mediated by upregulation of vascular endothelial growth factor and by downregulation of thrombospondin-1","volume":"152","author":"Yano","year":"2005","journal-title":"Br J Dermatol"},{"key":"10.1038\/labinvest.2014.66_bib24","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0002-9440(10)64522-1","article-title":"In vivo detection of human vascular endothelial growth factor promoter activity in transgenic mouse skin","volume":"157","author":"Kishimoto","year":"2000","journal-title":"Am J Pathol"},{"key":"10.1038\/labinvest.2014.66_bib25","first-page":"775","article-title":"Vascular endothelial growth factor is a marker of tumor invasion and metastasis in squamous cell carcinomas of the head and neck","volume":"5","author":"Sauter","year":"1999","journal-title":"Clin Cancer Res"},{"key":"10.1038\/labinvest.2014.66_bib26","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1034\/j.1600-0560.2002.291003.x","article-title":"Expression of vascular endothelial growth factor in basal cell carcinoma and cutaneous squamous cell carcinoma of the head and neck","volume":"29","author":"Bowden","year":"2002","journal-title":"J Cutan Pathol"},{"key":"10.1038\/labinvest.2014.66_bib27","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0002-9440(10)64715-3","article-title":"Expression of vascular endothelial growth factor induces an invasive phenotype in human squamous cell carcinomas","volume":"156","author":"Detmar","year":"2000","journal-title":"Am J Pathol"},{"key":"10.1038\/labinvest.2014.66_bib28","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1093\/jnci\/51.5.1417","article-title":"In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors","volume":"51","author":"Giard","year":"1973","journal-title":"J Natl Cancer Inst"},{"key":"10.1038\/labinvest.2014.66_bib29","first-page":"964","article-title":"Biphasic effects of 12-O-tetradecanoylphorbol-13-acetate on the cell morphology of low calcium-grown human epidermal carcinoma cells: involvement of translocation and down regulation of protein kinase C","volume":"48","author":"Kitajima","year":"1988","journal-title":"Cancer Res"},{"issue":"2 Pt 2","key":"10.1038\/labinvest.2014.66_bib30","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/0092-8674(80)90373-6","article-title":"Defective terminal differentiation in culture as a consistent and selectable character of malignant human keratinocytes","volume":"22","author":"Rheinwald","year":"1980","journal-title":"Cell"},{"key":"10.1038\/labinvest.2014.66_bib31","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1083\/jcb.106.3.761","article-title":"Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line","volume":"106","author":"Boukamp","year":"1988","journal-title":"J Cell Biol"},{"key":"10.1038\/labinvest.2014.66_bib32","first-page":"259","article-title":"A hemangioendothelioma-derived cell line: its use as a model for the study of endothelial cell biology","volume":"63","author":"Obeso","year":"1990","journal-title":"Lab Invest"},{"key":"10.1038\/labinvest.2014.66_bib33","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1093\/jnci\/81.12.938","article-title":"Enhanced tumorigenicity, melanogenesis, and metastases of a human malignant melanoma after implantation in nude mice","volume":"81","author":"Cornil","year":"1989","journal-title":"J Natl Cancer Inst"},{"key":"10.1038\/labinvest.2014.66_bib34","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1046\/j.1523-1747.1998.00378.x","article-title":"Molecular regulation of UVB-induced cutaneous angiogenesis","volume":"111","author":"Bielenberg","year":"1998","journal-title":"J Invest Dermatol"},{"key":"10.1038\/labinvest.2014.66_bib35","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1182\/blood-2005-05-1970","article-title":"Deletion of the selection cassette, but not cis-acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors","volume":"107","author":"Ema","year":"2006","journal-title":"Blood"},{"key":"10.1038\/labinvest.2014.66_bib36","doi-asserted-by":"crossref","first-page":"3657","DOI":"10.1073\/pnas.022017899","article-title":"Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis","volume":"99","author":"Takashima","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/labinvest.2014.66_bib37","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/j.ajpath.2012.04.013","article-title":"Increased smooth muscle contractility in mice deficient for neuropilin 2","volume":"181","author":"Bielenberg","year":"2012","journal-title":"Am J Pathol"},{"key":"10.1038\/labinvest.2014.66_bib38","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1046\/j.1523-1747.1999.00566.x","article-title":"Expression of interferon-beta is associated with growth arrest of murine and human epidermal cells","volume":"112","author":"Bielenberg","year":"1999","journal-title":"J Invest Dermatol"},{"key":"10.1038\/labinvest.2014.66_bib39","doi-asserted-by":"crossref","first-page":"4358","DOI":"10.1128\/jvi.68.7.4358-4368.1994","article-title":"Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice","volume":"68","author":"Arbeit","year":"1994","journal-title":"J Virol"},{"key":"10.1038\/labinvest.2014.66_bib40","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/1523-1747.ep12580383","article-title":"Effect of retinoic acid on cornified envelope formation: difference between spontaneous envelope formation in vivo or in vitro and expression of envelope competence","volume":"89","author":"Nagae","year":"1987","journal-title":"J Invest Dermatol"},{"key":"10.1038\/labinvest.2014.66_bib41","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.yexcr.2005.11.024","article-title":"Neuropilins in neoplasms: expression, regulation, and function","volume":"312","author":"Bielenberg","year":"2006","journal-title":"Exp Cell Res"},{"key":"10.1038\/labinvest.2014.66_bib42","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.1096\/fj.04-2320fje","article-title":"VEGF is required for the maintenance of dorsal root ganglia blood vessels but not neurons during development","volume":"18","author":"Kutcher","year":"2004","journal-title":"FASEB J"},{"key":"10.1038\/labinvest.2014.66_bib43","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1002\/1097-4644(20010401)81:1<82::AID-JCB1025>3.0.CO;2-P","article-title":"Neuropilin-1 expression in osteogenic cells: down-regulation during differentiation of osteoblasts into osteocytes","volume":"81","author":"Harper","year":"2001","journal-title":"J Cell Biochem"},{"key":"10.1038\/labinvest.2014.66_bib44","doi-asserted-by":"crossref","first-page":"639","DOI":"10.2353\/ajpath.2006.050834","article-title":"Vascular endothelial growth factor localization in the adult","volume":"168","author":"Maharaj","year":"2006","journal-title":"Am J Pathol"},{"key":"10.1038\/labinvest.2014.66_bib45","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1016\/S0002-9440(10)63772-8","article-title":"Neuropilin-1 in human colon cancer: expression, regulation, and role in induction of angiogenesis","volume":"164","author":"Parikh","year":"2004","journal-title":"Am J Pathol"},{"key":"10.1038\/labinvest.2014.66_bib46","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1038\/sj.bjc.6600811","article-title":"Induction of neuropilin-1 and vascular endothelial growth factor by epidermal growth factor in human gastric cancer cells","volume":"88","author":"Akagi","year":"2003","journal-title":"Br J Cancer"},{"key":"10.1038\/labinvest.2014.66_bib47","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1002\/cncr.11560","article-title":"Expression and regulation of the novel vascular endothelial growth factor receptor neuropilin-1 by epidermal growth factor in human pancreatic carcinoma","volume":"98","author":"Parikh","year":"2003","journal-title":"Cancer"},{"key":"10.1038\/labinvest.2014.66_bib48","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1001\/archdermatol.2010.19","article-title":"Incidence estimate of nonmelanoma skin cancer in the United States, 2006","volume":"146","author":"Rogers","year":"2010","journal-title":"Arch Dermatol"},{"key":"10.1038\/labinvest.2014.66_bib49","series-title":"Cancer Facts & Figures","author":"Society","year":"2013"},{"key":"10.1038\/labinvest.2014.66_bib50","first-page":"969618","article-title":"Surgical approaches to create murine models of human wound healing","volume":"2011","author":"Wong","year":"2011","journal-title":"J Biomed Biotechnol"},{"key":"10.1038\/labinvest.2014.66_bib51","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.yexcr.2005.11.012","article-title":"Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis","volume":"312","author":"Shibuya","year":"2006","journal-title":"Exp Cell Res"},{"key":"10.1038\/labinvest.2014.66_bib52","doi-asserted-by":"crossref","first-page":"127","DOI":"10.2119\/2006-00024.Man","article-title":"Immunolocalization and expression of vascular endothelial growth factor receptors (VEGFRs) and neuropilins (NRPs) on keratinocytes in human epidermis","volume":"12","author":"Man","year":"2006","journal-title":"Mol Med"},{"key":"10.1038\/labinvest.2014.66_bib53","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1111\/j.1582-4934.2007.00112.x","article-title":"Overexpression of vascular endothelial growth factor (VEGF) receptors on keratinocytes in psoriasis: regulated by calcium independent of VEGF","volume":"12","author":"Man","year":"2008","journal-title":"J Cell Mol Med"},{"key":"10.1038\/labinvest.2014.66_bib54","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1002\/bjs.6778","article-title":"Angiogenesis, vascular endothelial growth factor and its receptors in human surgical wounds","volume":"96","author":"Kumar","year":"2009","journal-title":"Br J Surg"},{"key":"10.1038\/labinvest.2014.66_bib55","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/S0002-9440(10)61213-8","article-title":"Novel function for vascular endothelial growth factor receptor-1 on epidermal keratinocytes","volume":"167","author":"Wilgus","year":"2005","journal-title":"Am J Pathol"},{"key":"10.1038\/labinvest.2014.66_bib56","doi-asserted-by":"crossref","first-page":"6519","DOI":"10.1523\/JNEUROSCI.19-15-06519.1999","article-title":"Cloning and characterization of neuropilin-1-interacting protein: a PSD-95\/Dlg\/ZO-1 domain-containing protein that interacts with the cytoplasmic domain of neuropilin-1","volume":"19","author":"Cai","year":"1999","journal-title":"J Neurosci"},{"key":"10.1038\/labinvest.2014.66_bib57","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1096\/fj.05-5504fje","article-title":"C terminus of RGS-GAIP-interacting protein conveys neuropilin-1-mediated signaling during angiogenesis","volume":"20","author":"Wang","year":"2006","journal-title":"FASEB J"},{"key":"10.1038\/labinvest.2014.66_bib58","doi-asserted-by":"crossref","first-page":"e1161","DOI":"10.1371\/journal.pone.0001161","article-title":"Neuropilin-1 modulates p53\/caspases axis to promote endothelial cell survival","volume":"2","author":"Wang","year":"2007","journal-title":"PloS One"},{"key":"10.1038\/labinvest.2014.66_bib59","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/j.cell.2013.01.036","article-title":"Targeting placental growth factor\/neuropilin 1 pathway inhibits growth and spread of medulloblastoma","volume":"152","author":"Snuderl","year":"2013","journal-title":"Cell"},{"key":"10.1038\/labinvest.2014.66_bib60","doi-asserted-by":"crossref","first-page":"2532","DOI":"10.1096\/fj.00-0250com","article-title":"Neuropilin-1 expression by tumor cells promotes tumor angiogenesis and progression","volume":"14","author":"Miao","year":"2000","journal-title":"FASEB J"},{"key":"10.1038\/labinvest.2014.66_bib61","doi-asserted-by":"crossref","first-page":"2036","DOI":"10.1182\/blood-2007-04-084269","article-title":"Neuropilin-1 and neuropilin-2 act as coreceptors, potentiating proangiogenic activity","volume":"111","author":"Sulpice","year":"2008","journal-title":"Blood"},{"issue":"5","key":"10.1038\/labinvest.2014.66_bib62","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1097\/PAT.0000000000000121","article-title":"Regulation of soluble neuropilin 1, an endogenous angiogenesis inhibitor, in liver development and regeneration","volume":"46","author":"Panigrahy","year":"2014","journal-title":"Pathology"}],"container-title":["Laboratory Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/labinvest201466.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/labinvest201466","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0023683722008170?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0023683722008170?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/labinvest201466.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T19:32:03Z","timestamp":1758396723000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0023683722008170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":62,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["S0023683722008170"],"URL":"https:\/\/doi.org\/10.1038\/labinvest.2014.66","relation":{},"ISSN":["0023-6837"],"issn-type":[{"value":"0023-6837","type":"print"}],"subject":[],"published":{"date-parts":[[2014,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neuropilin 1 expression correlates with differentiation status of epidermal cells and cutaneous squamous cell carcinomas","name":"articletitle","label":"Article Title"},{"value":"Laboratory Investigation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/labinvest.2014.66","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2014 United States & Canadian Academy of Pathology.","name":"copyright","label":"Copyright"}]}}