{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:27:36Z","timestamp":1777501656678,"version":"3.51.4"},"reference-count":41,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T00:00:00Z","timestamp":1673395200000},"content-version":"vor","delay-in-days":3116,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["li.uscap.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Laboratory Investigation"],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.1038\/labinvest.2014.71","type":"journal-article","created":{"date-parts":[[2014,6,2]],"date-time":"2014-06-02T08:39:47Z","timestamp":1401698387000},"page":"740-751","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Tumor necrosis factor-alpha-induced reduction of glomerular filtration rate in rats with fulminant hepatic failure"],"prefix":"10.1016","volume":"94","author":[{"given":"Jing-Bo","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong-Lei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hai-Tao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhao-Han","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Wen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cui-Ming","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Tong","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1038\/labinvest.2014.71_bib1","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1586\/17474124.2013.837264","article-title":"Acute kidney injury in acute liver failure: a review","volume":"7","author":"Moore","year":"2013","journal-title":"Expert Rev Gastroenterol Hepatol"},{"key":"10.1038\/labinvest.2014.71_bib2","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1055\/s-2008-1040323","article-title":"Pathogenesis and treatment of hepatorenal syndrome","volume":"28","author":"Arroyo","year":"2008","journal-title":"Semin Liver Dis"},{"key":"10.1038\/labinvest.2014.71_bib3","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1016\/S0140-6736(03)14903-3","article-title":"Hepatorenal syndrome","volume":"362","author":"Gines","year":"2003","journal-title":"Lancet"},{"key":"10.1038\/labinvest.2014.71_bib4","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1161\/01.HYP.37.2.635","article-title":"Angiotensin II signaling to phospholipase D in renal microvascular smooth muscle cells in SHR","volume":"37","author":"Andresen","year":"2001","journal-title":"Hypertension"},{"key":"10.1038\/labinvest.2014.71_bib5","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1161\/01.HYP.35.1.280","article-title":"Endothelin-mediated calcium signaling in preglomerular smooth muscle cells","volume":"35","author":"Schroeder","year":"2000","journal-title":"Hypertension"},{"key":"10.1038\/labinvest.2014.71_bib6","doi-asserted-by":"crossref","first-page":"F785","DOI":"10.1152\/ajprenal.00372.2004","article-title":"Angiotensin II Ca2+ signaling in rat afferent arterioles: stimulation of cyclic ADP ribose and IP3 pathways","volume":"288","author":"Fellner","year":"2005","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1038\/labinvest.2014.71_bib7","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1046\/j.1365-2168.1999.01045.x","article-title":"Noradrenaline improves the tumour to normal blood flow ratio and drug delivery in a model of liver metastases","volume":"86","author":"Shankar","year":"1999","journal-title":"Br J Surg"},{"key":"10.1038\/labinvest.2014.71_bib8","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1002\/hep.1840140313","article-title":"Systemic, splanchnic and renal hemodynamic effects of a dopaminergic dose of dopamine in patients with cirrhosis","volume":"14","author":"Bacq","year":"1991","journal-title":"Hepatology"},{"key":"10.1038\/labinvest.2014.71_bib9","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1001\/archinte.1975.00330070086014","article-title":"Response to dopamine hydrochloride in the hepatorenal syndrome","volume":"135","author":"Bennett","year":"1975","journal-title":"Arch Intern Med"},{"key":"10.1038\/labinvest.2014.71_bib10","doi-asserted-by":"crossref","first-page":"38","DOI":"10.3748\/wjg.v5.i1.38","article-title":"Detection of serum TNF-alpha,IFN-beta,IL-6 and IL-8 in patients with hepatitis B","volume":"5","author":"Wang","year":"1999","journal-title":"World J Gastroenterol"},{"key":"10.1038\/labinvest.2014.71_bib11","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1111\/j.1440-1746.2007.04846.x","article-title":"Possible involvement of cytokine gene polymorphisms in fulminant hepatitis","volume":"22","author":"Takakura","year":"2007","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1038\/labinvest.2014.71_bib12","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1053\/gast.2000.20189","article-title":"Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial","volume":"119","author":"Akriviadis","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1038\/labinvest.2014.71_bib13","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1093\/ndt\/gfq406","article-title":"TNFalpha-induced IP3R1 expression through TNFR1\/PC-PLC\/PKCalpha and TNFR2 signalling pathways in human mesangial cell","volume":"26","author":"Wang","year":"2011","journal-title":"Nephrol Dial Transplant"},{"key":"10.1038\/labinvest.2014.71_bib14","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/hep.20288","article-title":"Liposome-mediated extracellular superoxide dismutase gene delivery protects against acute liver injury in mice","volume":"40","author":"Wu","year":"2004","journal-title":"Hepatology"},{"key":"10.1038\/labinvest.2014.71_bib15","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1097\/SHK.0b013e31815d0780","article-title":"Insulin-like growth factor 1 prevents liver injury through the inhibition of TNF-alpha and iNOS induction in D-galactosamine and LPS-treated rats","volume":"29","author":"Hijikawa","year":"2008","journal-title":"Shock"},{"key":"10.1038\/labinvest.2014.71_bib16","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1258\/002367798780599866","article-title":"Saphenous vein puncture for blood sampling of the mouse, rat, hamster, gerbil, guinea pig, ferret and mink","volume":"32","author":"Hem","year":"1998","journal-title":"Lab Anim"},{"key":"10.1038\/labinvest.2014.71_bib17","doi-asserted-by":"crossref","first-page":"F590","DOI":"10.1152\/ajprenal.00324.2003","article-title":"Serial determination of glomerular filtration rate in conscious mice using FITC-inulin clearance","volume":"286","author":"Qi","year":"2004","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1038\/labinvest.2014.71_bib18","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S1567-5769(02)00259-X","article-title":"Immunomodulatory activity of TNF-alpha during acute liver injury induced by D-galactosamine and its protection by PGE1 in rats","volume":"3","author":"Lozano","year":"2003","journal-title":"Int Immunopharmacol"},{"key":"10.1038\/labinvest.2014.71_bib19","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1136\/gut.47.4.553","article-title":"TNF-alpha dependent production of inducible nitric oxide is involved in PGE(1) protection against acute liver injury","volume":"47","author":"Muntane","year":"2000","journal-title":"Gut"},{"key":"10.1038\/labinvest.2014.71_bib20","doi-asserted-by":"crossref","first-page":"G623","DOI":"10.1152\/ajpgi.00521.2006","article-title":"2-APB protects against liver ischemia-reperfusion injury by reducing cellular and mitochondrial calcium uptake","volume":"293","author":"Nicoud","year":"2007","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1038\/labinvest.2014.71_bib21","first-page":"F172","article-title":"A simple, nonradioactive method for evaluating single-nephron filtration rate using FITC-inulin","volume":"276","author":"Lorenz","year":"1999","journal-title":"Am J Physiol"},{"key":"10.1038\/labinvest.2014.71_bib22","doi-asserted-by":"crossref","first-page":"2154","DOI":"10.1152\/jappl.1998.84.6.2154","article-title":"Rapid determination of glomerular filtration rate by single-bolus inulin: a comparison of estimation analyses","volume":"84","author":"Sturgeon","year":"1998","journal-title":"J Appl Physiol"},{"key":"10.1038\/labinvest.2014.71_bib23","first-page":"111","article-title":"Effect of cAMP analogues on glomerular inulin space of isolated rats renal glomeruli","volume":"56","author":"van Bemmelen","year":"2005","journal-title":"J Physiol Pharmacol"},{"key":"10.1038\/labinvest.2014.71_bib24","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1038\/sj.bjp.0706149","article-title":"Effects of diadenosine polyphosphates on glomerular volume","volume":"144","author":"Szczepanska-Konkel","year":"2005","journal-title":"Br J Pharmacol"},{"key":"10.1038\/labinvest.2014.71_bib25","doi-asserted-by":"crossref","first-page":"F760","DOI":"10.1152\/ajprenal.00422.2004","article-title":"Calcium and chloride channel activation by angiotensin II-AT1 receptors in preglomerular vascular smooth muscle cells","volume":"289","author":"Fuller","year":"2005","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1038\/labinvest.2014.71_bib26","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/s10157-012-0588-4","article-title":"Characteristics of spontaneous calcium oscillations in renal tubular epithelial cells","volume":"16","author":"Udagawa","year":"2012","journal-title":"Clin Exp Nephrol"},{"key":"10.1038\/labinvest.2014.71_bib27","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1002\/hep.21179","article-title":"Renal damage in experimentally-induced cirrhosis in rats: Role of oxygen free radicals","volume":"43","author":"Natarajan","year":"2006","journal-title":"Hepatology"},{"key":"10.1038\/labinvest.2014.71_bib28","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1136\/gut.52.2.293","article-title":"Effect of neonatal capsaicin treatment on haemodynamics and renal function in cirrhotic rats","volume":"52","author":"Li","year":"2003","journal-title":"Gut"},{"key":"10.1038\/labinvest.2014.71_bib29","doi-asserted-by":"crossref","first-page":"H481","DOI":"10.1152\/ajpheart.00507.2005","article-title":"Effect of phosphodiesterase 5 inhibitor on alteration in vascular smooth muscle sensitivity and renal function in rats with liver cirrhosis","volume":"290","author":"Tahseldar-Roumieh","year":"2006","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1038\/labinvest.2014.71_bib30","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1111\/j.1523-1755.2005.67118.x","article-title":"Sodium retention in cirrhotic rats is associated with increased renal abundance of sodium transporter proteins","volume":"67","author":"Fernandez-Llama","year":"2005","journal-title":"Kidney Int"},{"key":"10.1038\/labinvest.2014.71_bib31","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S1665-2681(19)31833-2","article-title":"Acute renal failure induced by carbon tetrachloride in rats with hepatic cirrhosis","volume":"7","author":"Jaramillo-Juarez","year":"2008","journal-title":"Ann Hepatol"},{"key":"10.1038\/labinvest.2014.71_bib32","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1038\/labinvest.2008.124","article-title":"Acute kidney injury after hepatic ischemia and reperfusion injury in mice","volume":"89","author":"Lee","year":"2009","journal-title":"Lab Invest"},{"key":"10.1038\/labinvest.2014.71_bib33","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1097\/SMJ.0b013e3181e07751","article-title":"Hepatorenal syndrome","volume":"103","author":"Venkat","year":"2010","journal-title":"South Med J"},{"key":"10.1038\/labinvest.2014.71_bib34","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1124\/jpet.102.043539","article-title":"Neurokinin-1 receptor antagonists CP-96 345 and L-733 060 protect mice from cytokine-mediated liver injury","volume":"305","author":"Bang","year":"2003","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1038\/labinvest.2014.71_bib35","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1016\/j.jhep.2005.09.019","article-title":"Matrix metalloproteinase-9 contributes to brain extravasation and edema in fulminant hepatic failure mice","volume":"44","author":"Nguyen","year":"2006","journal-title":"J Hepatol"},{"key":"10.1038\/labinvest.2014.71_bib36","doi-asserted-by":"crossref","first-page":"806","DOI":"10.3109\/0886022X.2013.794680","article-title":"Exogenous normal lymph alleviates lipopolysaccharide-induced acute kidney injury in rats","volume":"35","author":"Zhao","year":"2013","journal-title":"Ren Fail"},{"key":"10.1038\/labinvest.2014.71_bib37","doi-asserted-by":"crossref","first-page":"C195","DOI":"10.1152\/ajpcell.00374.2002","article-title":"Inositol 1,4,5-trisphosphate receptors modulate Ca2+ sparks and Ca2+ store content in vas deferens myocytes","volume":"285","author":"White","year":"2003","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1038\/labinvest.2014.71_bib38","doi-asserted-by":"crossref","first-page":"33069","DOI":"10.1074\/jbc.M802209200","article-title":"Tumor necrosis factor-alpha potentiates intraneuronal Ca2+ signaling via regulation of the inositol 1,4,5-trisphosphate receptor","volume":"283","author":"Park","year":"2008","journal-title":"J Biol Chem"},{"key":"10.1038\/labinvest.2014.71_bib39","doi-asserted-by":"crossref","first-page":"2656","DOI":"10.1172\/JCI26373","article-title":"Endoplasmic reticulum stress: cell life and death decisions","volume":"115","author":"Xu","year":"2005","journal-title":"J Clin Invest"},{"key":"10.1038\/labinvest.2014.71_bib40","first-page":"F1239","article-title":"Angiotensin II-receptor stimulation of cytosolic calcium concentration in cultured renal resistance arterioles","volume":"271","author":"Zhu","year":"1996","journal-title":"Am J Physiol"},{"key":"10.1038\/labinvest.2014.71_bib41","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1038\/ki.2012.393","article-title":"The synthetic triterpenoid, RTA 405, increases the glomerular filtration rate and reduces angiotensin II-induced contraction of glomerular mesangial cells","volume":"83","author":"Ding","year":"2013","journal-title":"Kidney Int"}],"container-title":["Laboratory Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/labinvest201471.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/labinvest201471","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0023683722008169?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0023683722008169?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/labinvest201471.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T19:32:22Z","timestamp":1758396742000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0023683722008169"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":41,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["S0023683722008169"],"URL":"https:\/\/doi.org\/10.1038\/labinvest.2014.71","relation":{},"ISSN":["0023-6837"],"issn-type":[{"value":"0023-6837","type":"print"}],"subject":[],"published":{"date-parts":[[2014,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Tumor necrosis factor-alpha-induced reduction of glomerular filtration rate in rats with fulminant hepatic failure","name":"articletitle","label":"Article Title"},{"value":"Laboratory Investigation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/labinvest.2014.71","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2014 United States & Canadian Academy of Pathology.","name":"copyright","label":"Copyright"}]}}