{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T23:00:21Z","timestamp":1773270021285,"version":"3.50.1"},"reference-count":79,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T00:00:00Z","timestamp":1673395200000},"content-version":"vor","delay-in-days":8045,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["li.uscap.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Laboratory Investigation"],"published-print":{"date-parts":[[2001,1]]},"DOI":"10.1038\/labinvest.3780214","type":"journal-article","created":{"date-parts":[[2012,2,23]],"date-time":"2012-02-23T04:47:25Z","timestamp":1329972445000},"page":"83-93","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"title":["Localization of Tissue Transglutaminase in Human Carotid and Coronary Artery Atherosclerosis: Implications for Plaque Stability and Progression"],"prefix":"10.1016","volume":"81","author":[{"given":"Zishan A","family":"Haroon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Wannenburg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madhu","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles S","family":"Greenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reidar","family":"Wallin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David C","family":"Sane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1038\/labinvest.3780214_bib1","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1136\/hrt.82.3.269","article-title":"Plaque erosion is a major substrate for coronary thrombosis in acute myocardial infarction","volume":"82","author":"Arbustini","year":"1999","journal-title":"Heart"},{"key":"10.1038\/labinvest.3780214_bib2","doi-asserted-by":"crossref","first-page":"5667","DOI":"10.1021\/bi00367a048","article-title":"Thrombospondin is a substrate for blood coagulation factor XIIIa","volume":"25","author":"Bale","year":"1986","journal-title":"Biochemistry"},{"key":"10.1038\/labinvest.3780214_bib3","doi-asserted-by":"crossref","first-page":"41G","DOI":"10.1016\/0002-9149(90)90394-G","article-title":"Rupture of coronary vasa vasorum as a trigger of acute myocardial infarction","volume":"66","author":"Barger","year":"1990","journal-title":"Am J Cardiol"},{"key":"10.1038\/labinvest.3780214_bib4","doi-asserted-by":"crossref","first-page":"20313","DOI":"10.1074\/jbc.272.33.20313","article-title":"Protein oxidation in aging, disease, and oxidative stress","volume":"272","author":"Berlett","year":"1997","journal-title":"J Biol Chem"},{"key":"10.1038\/labinvest.3780214_bib5","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/j.1749-6632.1999.tb07924.x","article-title":"Regulation of transglutaminases by nitric oxide","volume":"887","author":"Bernassola","year":"1999","journal-title":"Ann NY Acad Sci"},{"key":"10.1038\/labinvest.3780214_bib6","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1111\/j.1749-6632.1978.tb16813.x","article-title":"Cellular transglutaminase, growth and transformation","volume":"312","author":"Birckbichler","year":"1978","journal-title":"Annals NY Acad Sci"},{"key":"10.1038\/labinvest.3780214_bib7","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1089\/hyb.1985.4.179","article-title":"A monoclonal antibody to cellular transglutaminase","volume":"4","author":"Birckbichler","year":"1985","journal-title":"Hybridoma"},{"key":"10.1038\/labinvest.3780214_bib8","doi-asserted-by":"crossref","first-page":"18149","DOI":"10.1016\/S0021-9258(18)55248-0","article-title":"Lipoprotein (a) is a substrate for factor XIIIa and tissue transglutaminase","volume":"266","author":"Borth","year":"1991","journal-title":"J Biol Chem"},{"key":"10.1038\/labinvest.3780214_bib9","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/0304-4165(88)90014-1","article-title":"Increased transglutaminase activity during skin wound healing in rats","volume":"967","author":"Bowness","year":"1988","journal-title":"Biochim Biophys Acta"},{"key":"10.1038\/labinvest.3780214_bib10","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1006\/bbrc.1998.9130","article-title":"Inhibition of clotting factor XIII activity by nitric oxide","volume":"249","author":"Catani","year":"1998","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1038\/labinvest.3780214_bib11","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1161\/01.CIR.94.8.2013","article-title":"Stability and instability: The two faces of coronary atherosclerosis. Paul Dudley White Lecture 1995","volume":"94","author":"Davies","year":"1996","journal-title":"Circulation"},{"key":"10.1038\/labinvest.3780214_bib12","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1056\/NEJM199705013361809","article-title":"The composition of coronary artery plaques","volume":"336","author":"Davies","year":"1997","journal-title":"N Engl J Med"},{"issue":"Suppl 1","key":"10.1038\/labinvest.3780214_bib13","first-page":"33","article-title":"Lipid and cellular constituents of unstable human aortic plaques","volume":"89","author":"Davies","year":"1994","journal-title":"Basic Res Cardiol"},{"key":"10.1038\/labinvest.3780214_bib14","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1161\/01.RES.77.5.863","article-title":"Matrix metalloproteinases and cardiovascular disease","volume":"77","author":"Dellery","year":"1995","journal-title":"Circ Res"},{"key":"10.1038\/labinvest.3780214_bib15","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1161\/01.ATV.18.2.168","article-title":"Vitronectin expression and interaction with receptors in smooth muscle cells from human atheromatous plaque","volume":"18","author":"Dufourcq","year":"1998","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"Suppl III","key":"10.1038\/labinvest.3780214_bib16","first-page":"30","article-title":"Progressive atherogenesis: Why do plaques rupture","volume":"86","author":"Falk","year":"1992","journal-title":"Circulation"},{"key":"10.1038\/labinvest.3780214_bib17","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0014-5793(91)80773-V","article-title":"Degradation of cells dying by apoptosis leads to accumulation of \u03b5(\u03b3-glutamyl)lysine isodipeptide in culture fluid and blood","volume":"284","author":"Fesus","year":"1991","journal-title":"FEBS Lett"},{"key":"10.1038\/labinvest.3780214_bib18","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/0014-5793(89)80210-8","article-title":"Apoptotic hepatocytes become insoluble in detergents and chaotropic agents as a result of transglutaminase action","volume":"245","author":"Fesus","year":"1989","journal-title":"FEBS Lett"},{"key":"10.1038\/labinvest.3780214_bib19","first-page":"1","article-title":"Mechanism and basis for specificity of transglutaminase-catalyzed \u03b5-(\u03b3-glutamyl)lysine bond formation","volume":"54","author":"Folk","year":"1983","journal-title":"Adv Enzymol Relat Areas Mol Biol"},{"key":"10.1038\/labinvest.3780214_bib20","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1161\/01.CIR.98.7.699","article-title":"Resident cardiac mast cells degranulate and release preformed TNF-alpha, initiating the cytokine cascade in experimental myocardial ischemia\/reperfusion","volume":"98","author":"Frangogiannis","year":"1998","journal-title":"Circulation"},{"key":"10.1038\/labinvest.3780214_bib21","doi-asserted-by":"crossref","first-page":"2493","DOI":"10.1172\/JCI117619","article-title":"Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques","volume":"94","author":"Galis","year":"1994","journal-title":"J Clin Invest"},{"key":"10.1038\/labinvest.3780214_bib22","first-page":"251","article-title":"Evidence for apoptosis in advanced human atheroma. Colocalization with interleukin-1 beta-converting enzyme","volume":"147","author":"Geng","year":"1995","journal-title":"Am J Pathol"},{"key":"10.1038\/labinvest.3780214_bib23","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/S0021-9258(18)52460-1","article-title":"Isolation and characterization of cDNA clones to mouse macrophage and human endothelial cell tissue transglutaminases","volume":"266","author":"Gentile","year":"1991","journal-title":"J Biol Chem"},{"key":"10.1038\/labinvest.3780214_bib24","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1083\/jcb.119.2.463","article-title":"Expression of tissue transglutaminase in BALB-C 3T3 fibroblasts: Effects on cellular morphology and adhesion","volume":"119","author":"Gentile","year":"1992","journal-title":"J Cell Biol"},{"key":"10.1038\/labinvest.3780214_bib25","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1749-6632.1995.tb44624.x","article-title":"Osteopontin expression in cardiovascular diseases","volume":"760","author":"Giachelli","year":"1995","journal-title":"Annal NY Acad Sci"},{"key":"10.1038\/labinvest.3780214_bib26","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1182\/blood.V70.3.702.702","article-title":"The transglutaminase in vascular cells and tissues could provide an alternate pathway for fibrin stabilization","volume":"70","author":"Greenberg","year":"1987","journal-title":"Blood"},{"key":"10.1038\/labinvest.3780214_bib27","doi-asserted-by":"crossref","first-page":"3071","DOI":"10.1096\/fasebj.5.15.1683845","article-title":"Transglutaminases: Multifunctional cross-linking enzymes that stabilize tissues","volume":"5","author":"Greenberg","year":"1991","journal-title":"FASEB J"},{"key":"10.1038\/labinvest.3780214_bib28","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1146\/annurev.med.47.1.423","article-title":"The role of lipoprotein (a) in atherogenesis and thrombosis","volume":"47","author":"Hajjar","year":"1996","journal-title":"Annu Rev Med"},{"issue":"Suppl 2","key":"10.1038\/labinvest.3780214_bib29","first-page":"11","article-title":"Endothelial function and oxidant stress","volume":"20","author":"Harrison","year":"1997","journal-title":"Clin Cardiol"},{"key":"10.1038\/labinvest.3780214_bib30","doi-asserted-by":"crossref","first-page":"2995","DOI":"10.1172\/JCI119853","article-title":"Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy","volume":"100","author":"Horie","year":"1997","journal-title":"J Clin Invest"},{"key":"10.1038\/labinvest.3780214_bib31","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1177\/29.4.6166661","article-title":"Use of avidin-biotin peroxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC unlabeled antibody (PAP) procedures","volume":"29","author":"Hsu","year":"1981","journal-title":"J Histochem Cytochem"},{"key":"10.1038\/labinvest.3780214_bib32","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1348-0421.1989.tb01497.x","article-title":"Influence of transglutaminase on the functions of mouse peritoneal macrophages","volume":"33","author":"Ishitani","year":"1989","journal-title":"Microbiol Immunol"},{"key":"10.1038\/labinvest.3780214_bib33","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/S0735-1097(98)00283-6","article-title":"Mast cell infiltration in acute coronary syndromes: Implications for plaque rupture","volume":"32","author":"Kaartinen","year":"1998","journal-title":"J Am Coll Cardiol"},{"key":"10.1038\/labinvest.3780214_bib34","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1126\/science.6701530","article-title":"Coronary arteries of cardiac patients are hyperreactive and contain stores of amines: A mechanism for coronary spasm","volume":"223","author":"Kalsner","year":"1984","journal-title":"Science"},{"key":"10.1038\/labinvest.3780214_bib35","doi-asserted-by":"crossref","first-page":"17891","DOI":"10.1016\/S0021-9258(18)38247-4","article-title":"Formation of high molecular weight dermatan sulfate proteoglycan in bovine aortic endothelial cell cultures. Evidence for transglutaminase-catalyzed cross-linking to fibronectin","volume":"265","author":"Kinsella","year":"1990","journal-title":"J Biol Chem"},{"key":"10.1038\/labinvest.3780214_bib36","doi-asserted-by":"crossref","first-page":"9410","DOI":"10.1074\/jbc.272.14.9410","article-title":"Dimerization of midkine by tissue transglutaminase and its functional implication","volume":"272","author":"Kojima","year":"1997","journal-title":"J Biol Chem"},{"key":"10.1038\/labinvest.3780214_bib37","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1083\/jcb.121.2.439","article-title":"Requirement for transglutaminase in the activation of latent transforming growth factor-\u03b2 in bovine endothelial cells","volume":"121","author":"Kojima","year":"1993","journal-title":"J Cell Biol"},{"key":"10.1038\/labinvest.3780214_bib38","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1161\/01.CIR.92.5.1084","article-title":"Infiltrates of activated mast cells at the site of coronary atheromatous erosion or rupture in myocardial infarction","volume":"92","author":"Kovanen","year":"1995","journal-title":"Circulation"},{"key":"10.1038\/labinvest.3780214_bib39","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1016\/0735-1097(94)90369-7","article-title":"Vascular mechanics for the cardiologist","volume":"23","author":"Lee","year":"1994","journal-title":"J Am Coll Cardiol"},{"key":"10.1038\/labinvest.3780214_bib40","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1161\/01.ATV.17.10.1859","article-title":"The unstable atheroma","volume":"17","author":"Lee","year":"1997","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1038\/labinvest.3780214_bib41","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0021-9150(91)90235-U","article-title":"Atherosclerotic plaque caps are locally weakened when macrophage density is increased","volume":"87","author":"Lendon","year":"1991","journal-title":"Atherosclerosis"},{"key":"10.1038\/labinvest.3780214_bib42","first-page":"1","article-title":"Vascular biology of the acute coronary syndromes","author":"Libby","year":"1998","journal-title":"Acute coronary syndromes"},{"key":"10.1038\/labinvest.3780214_bib43","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1161\/01.RES.71.4.850","article-title":"Effects of fibrous cap thickness on peak circumferential stress in model atherosclerotic vessels","volume":"71","author":"Loree","year":"1992","journal-title":"Circ Res"},{"key":"10.1038\/labinvest.3780214_bib44","doi-asserted-by":"crossref","first-page":"2538","DOI":"10.1021\/bi00175a024","article-title":"Transglutaminase-mediated processing of fibronectin by endothelial cell monolayers","volume":"33","author":"Martinez","year":"1994","journal-title":"Biochemistry"},{"key":"10.1038\/labinvest.3780214_bib45","doi-asserted-by":"crossref","first-page":"20502","DOI":"10.1016\/S0021-9258(19)47090-7","article-title":"Transglutaminase-mediated cross-linking of fibrinogen by human umbilical vein endothelial cells","volume":"264","author":"Martinez","year":"1989","journal-title":"J Biol Chem"},{"key":"10.1038\/labinvest.3780214_bib46","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1146\/annurev.cb.06.110190.003121","article-title":"The transforming growth factor-\u03b2 family","volume":"6","author":"Massagu\u00e9","year":"1990","journal-title":"Annu Rev Cell Biol"},{"key":"10.1038\/labinvest.3780214_bib47","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S0741-5214(99)70136-9","article-title":"Angiogenesis and the atherosclerotic carotid plaque: An association between symptomatology and plaque morphology","volume":"30","author":"McCarthy","year":"1999","journal-title":"J Vasc Surg"},{"key":"10.1038\/labinvest.3780214_bib48","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1038\/41237","article-title":"S-nitrosylation regulates apoptosis","volume":"388","author":"Melino","year":"1997","journal-title":"Nature"},{"key":"10.1038\/labinvest.3780214_bib49","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/BF00240605","article-title":"Cross-linking of fibronectin to collagenous proteins","volume":"58","author":"Mosher","year":"1984","journal-title":"Mol Cell Biochem"},{"key":"10.1038\/labinvest.3780214_bib50","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1126\/science.7911253","article-title":"Gh: A GTP-binding protein with transglutaminase activity and receptor signaling function","volume":"264","author":"Nakaoka","year":"1994","journal-title":"Science"},{"key":"10.1038\/labinvest.3780214_bib51","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1083\/jcb.136.5.1151","article-title":"Latent transforming growth factor-beta binding protein domains involved in activation and transglutminase-dependent cross-linking of latent transforming growth factor-beta","volume":"136","author":"Nunes","year":"1997","journal-title":"J Cell Biol"},{"key":"10.1038\/labinvest.3780214_bib52","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.4049\/jimmunol.155.3.1450","article-title":"Characterization of latent TGF-beta activation by murine peritoneal macrophages","volume":"155","author":"Nunes","year":"1995","journal-title":"J Immunol"},{"key":"10.1038\/labinvest.3780214_bib53","doi-asserted-by":"crossref","first-page":"2546","DOI":"10.1172\/JCI116491","article-title":"Hypercholesterolemia increases endothelial superoxide anion production","volume":"91","author":"Ohara","year":"1993","journal-title":"J Clin Invest"},{"key":"10.1038\/labinvest.3780214_bib54","first-page":"474","article-title":"Capillary rupture with intimal hemorrhage as a causative factor in coronary thrombosis","volume":"25","author":"Paterson","year":"1938","journal-title":"Arch Pathol"},{"key":"10.1038\/labinvest.3780214_bib55","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/0006-291X(91)90669-X","article-title":"Osteopontin, a substrate for transglutaminase and factor XIII activity","volume":"177","author":"Prince","year":"1991","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1038\/labinvest.3780214_bib56","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/S0006-291X(84)80086-8","article-title":"Inactivation of alpha-1-proteinase inhibitor by gas phase cigarettes smoke","volume":"122","author":"Pryor","year":"1984","journal-title":"Biochem Biohys Res Commun"},{"key":"10.1038\/labinvest.3780214_bib57","first-page":"1634","article-title":"Type I collagen gene expression in human atherosclerosis. Localization to specific plaque regions","volume":"143","author":"Rekhter","year":"1993","journal-title":"Am J Pathol"},{"key":"10.1038\/labinvest.3780214_bib58","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/S0140-6736(89)90953-7","article-title":"Influence of plaque configuration and stress distribution on fissuring of coronary atherosclerotic plaque","volume":"2","author":"Richardson","year":"1989","journal-title":"Lancet"},{"key":"10.1038\/labinvest.3780214_bib59","first-page":"962","article-title":"Regional differences in the distribution of biglycan and decorin in the extracellular matrix of atherosclerotic and restenotic human coronary arteries","volume":"144","author":"Riessen","year":"1994","journal-title":"Am J Pathol"},{"key":"10.1038\/labinvest.3780214_bib60","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1002\/ijc.2910480211","article-title":"Differential expression of isopeptide bonds N\u03b5(\u03b3-glutamyl)lysine in benign and malignant human breast lesions: An immunohistochemical study","volume":"48","author":"Roem","year":"1991","journal-title":"Int J Cancer"},{"key":"10.1038\/labinvest.3780214_bib61","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1161\/01.RES.83.3.264","article-title":"Factor XIIIa cross-links lipoprotein (a) with fibrinogen and is present in human atherosclerotic lesions","volume":"83","author":"Romanic","year":"1998","journal-title":"Circ Res"},{"key":"10.1038\/labinvest.3780214_bib62","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1002\/jlb.39.6.629","article-title":"Inactivation of alveolar macrophage transglutaminase by oxidants in cigarette smoke","volume":"39","author":"Roth","year":"1986","journal-title":"J Leukoc Biol"},{"key":"10.1038\/labinvest.3780214_bib63","doi-asserted-by":"crossref","first-page":"3543","DOI":"10.1016\/S0021-9258(19)39803-5","article-title":"Highly sulfated glycosaminoglycans augment the cross-linking of vitronectin by guinea pig liver transglutaminase","volume":"265","author":"Sane","year":"1990","journal-title":"J Biol Chem"},{"key":"10.1038\/labinvest.3780214_bib64","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1042\/bj3400569","article-title":"The trappin gene family: Proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide core","volume":"340","author":"Schalkwijk","year":"1999","journal-title":"Biochem J"},{"key":"10.1038\/labinvest.3780214_bib65","doi-asserted-by":"crossref","first-page":"21609","DOI":"10.1074\/jbc.272.34.21609","article-title":"Angiotensin II increases macrophage-mediated modification of low density lipoprotein via a lipoxygenase-dependent pathway","volume":"272","author":"Scheidegger","year":"1997","journal-title":"J Biol Chem"},{"key":"10.1038\/labinvest.3780214_bib66","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1172\/JCI118175","article-title":"Advanced glycation end products interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice: A potential mechanism for the accelerated vasculopathy of diabetes","volume":"96","author":"Schmidt","year":"1995","journal-title":"J Clin Invest"},{"key":"10.1038\/labinvest.3780214_bib67","doi-asserted-by":"crossref","first-page":"II38","DOI":"10.1002\/j.1932-8737.1997.tb00011.x","article-title":"Plaque disruption and coronary thrombosis: New insights into pathogenesis and prevention","volume":"20","author":"Shah","year":"1997","journal-title":"Clin Cardiol"},{"key":"10.1038\/labinvest.3780214_bib68","first-page":"1565","article-title":"Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques: Potential role of matrix degrading metalloproteinases and implications for plaque rupture","volume":"92","author":"Shah","year":"1995","journal-title":"Circulation"},{"key":"10.1038\/labinvest.3780214_bib69","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/0021-9150(72)90079-2","article-title":"Deposition of modified fibrinogen within the aortic intima","volume":"16","author":"Shainoff","year":"1972","journal-title":"Atherosclerosis"},{"key":"10.1038\/labinvest.3780214_bib70","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0021-9150(87)90259-0","article-title":"Relative distribution of fibronectin and type I, III, IV, V collagens in normal and atherosclerotic intima of human arteries","volume":"676","author":"Shekhonin","year":"1987","journal-title":"Atherosclerosis"},{"key":"10.1038\/labinvest.3780214_bib71","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/0003-2697(92)90594-W","article-title":"A microtiter plate transglutaminase assay utilizing 5-(biotinamido)pentylamine as substrate","volume":"205","author":"Slaughter","year":"1992","journal-title":"Anal Biochem"},{"key":"10.1038\/labinvest.3780214_bib72","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1042\/bj1470153","article-title":"Transamidase kinetics. Amide formation in the enzymic reactions of thiol esters with amines","volume":"147","author":"Stenberg","year":"1975","journal-title":"Biochem J"},{"key":"10.1038\/labinvest.3780214_bib73","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1177\/18.5.315","article-title":"The unlabeled antibody enzyme method of immunohistochemistry: Preparation and properties of soluble antigen-antibody (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes","volume":"18","author":"Sternberger","year":"1970","journal-title":"J Histochem Cytochem"},{"key":"10.1038\/labinvest.3780214_bib74","first-page":"201","article-title":"EPR adsorption by the vapor phase of cigarette smoke, condensed and examined at low temperatures","volume":"7","author":"Tully","year":"1969","journal-title":"Chem Ind"},{"key":"10.1038\/labinvest.3780214_bib75","first-page":"861","article-title":"Immunoelectrophorectic and immunohistochemical characterizations of fibrinogen derivatives in atherosclerotic aortic intimas and vascular prosthesis pseudo-intimas","volume":"141","author":"Valenzuela","year":"1992","journal-title":"Am J Pathol"},{"key":"10.1038\/labinvest.3780214_bib76","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1161\/01.CIR.89.1.36","article-title":"Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology","volume":"89","author":"van der Wal","year":"1994","journal-title":"Circulation"},{"key":"10.1038\/labinvest.3780214_bib77","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1177\/33.4.3884704","article-title":"Light microscopic immunolocation of thrombospondin in human tissues","volume":"33","author":"Wight","year":"1985","journal-title":"J Histochem Cytochem"},{"key":"10.1038\/labinvest.3780214_bib78","doi-asserted-by":"crossref","first-page":"18802","DOI":"10.1016\/S0021-9258(18)55134-6","article-title":"Potential role of entactin in hemostasis. Specific interaction of entactin with fibrinogen A alpha and B beta chains","volume":"266","author":"Wu","year":"1991","journal-title":"J Biol Chem"},{"key":"10.1038\/labinvest.3780214_bib79","first-page":"164","article-title":"Immunohistochemical study of intimal microvessels in coronary atherosclerosis","volume":"143","author":"Zhang","year":"1993","journal-title":"Am J Pathol"}],"container-title":["Laboratory Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/3780214.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/3780214","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0023683722020359?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0023683722020359?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/3780214.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T19:45:02Z","timestamp":1758397502000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0023683722020359"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,1]]},"references-count":79,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,1]]}},"alternative-id":["S0023683722020359"],"URL":"https:\/\/doi.org\/10.1038\/labinvest.3780214","relation":{},"ISSN":["0023-6837"],"issn-type":[{"value":"0023-6837","type":"print"}],"subject":[],"published":{"date-parts":[[2001,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Localization of Tissue Transglutaminase in Human Carotid and Coronary Artery Atherosclerosis: Implications for Plaque Stability and Progression","name":"articletitle","label":"Article Title"},{"value":"Laboratory Investigation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/labinvest.3780214","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2001 United States & Canadian Academy of Pathology.","name":"copyright","label":"Copyright"}]}}