{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:24:14Z","timestamp":1761513854546},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Leukemia"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1038\/leu.2016.216","type":"journal-article","created":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T13:19:36Z","timestamp":1470057576000},"page":"2273-2275","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Vascular events and risk factors for thrombosis in refractory anemia with ring sideroblasts and thrombocytosis"],"prefix":"10.1038","volume":"30","author":[{"given":"M M","family":"Patnaik","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T L","family":"Lasho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C M","family":"Finke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C A","family":"Hanson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R L","family":"King","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R P","family":"Ketterling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Gangat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Tefferi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,8,1]]},"reference":[{"key":"BFleu2016216_CR1","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1002\/ajh.24038","volume":"90","author":"MM Patnaik","year":"2015","unstructured":"Patnaik MM, Tefferi A . Refractory anemia with ring sideroblasts and RARS with thrombocytosis. Am J Hematol 2015; 90: 549\u2013559.","journal-title":"Am J Hematol"},{"key":"BFleu2016216_CR2","volume-title":"WHO Classification of Tumors of Haematopoietic and Lymphoid Tissues","author":"S Swerdlow","year":"2008","unstructured":"Swerdlow S, Camp E, Harris NL, Jaffe ES, Stefano PA et al (ed). WHO Classification of Tumors of Haematopoietic and Lymphoid Tissues. International Agency for Research on Cancer: Lyon, 2008."},{"key":"BFleu2016216_CR3","doi-asserted-by":"publisher","first-page":"e125","DOI":"10.3324\/haematol.2014.119032","volume":"100","author":"S Jeromin","year":"2015","unstructured":"Jeromin S, Haferlach T, Weissmann S, Meggendorfer M, Eder C, Nadarajah N et al. Refractory anemia with ring sideroblasts and marked thrombocytosis cases harbor mutations in SF3B1 or other spliceosome genes accompanied by JAK2V617F and ASXL1 mutations. Haematologica 2015; 100: e125\u2013e127.","journal-title":"Haematologica"},{"key":"BFleu2016216_CR4","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1002\/ajh.24332","volume":"91","author":"MM Patnaik","year":"2016","unstructured":"Patnaik MM, Lasho TL, Finke CM, Hanson CA, King RL, Ketterling RP et al. Predictors of survival in refractory anemia with ring sideroblasts and thrombocytosis (RARS-T) and the role of next-generation sequencing. Am J Hematol 2016; 91: 492\u2013498.","journal-title":"Am J Hematol"},{"key":"BFleu2016216_CR5","doi-asserted-by":"publisher","first-page":"1036","DOI":"10.3324\/haematol.2011.053918","volume":"97","author":"J Broseus","year":"2012","unstructured":"Broseus J, Florensa L, Zipperer E, Schnittger S, Malcovati L, Richebourg S et al. Clinical features and course of refractory anemia with ring sideroblasts associated with marked thrombocytosis. Haematologica 2012; 97: 1036\u20131041.","journal-title":"Haematologica"},{"key":"BFleu2016216_CR6","doi-asserted-by":"publisher","first-page":"5128","DOI":"10.1182\/blood-2012-07-444067","volume":"120","author":"T Barbui","year":"2012","unstructured":"Barbui T, Finazzi G, Carobbio A, Thiele J, Passamonti F, Rumi E et al. Development and validation of an International Prognostic Score of thrombosis in World Health Organization-essential thrombocythemia (IPSET-thrombosis). Blood 2012; 120: 5128\u20135133.","journal-title":"Blood"},{"key":"BFleu2016216_CR7","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1038\/leu.2011.232","volume":"26","author":"V Visconte","year":"2012","unstructured":"Visconte V, Makishima H, Jankowska A, Szpurka H, Traina F, Jerez A et al. SF3B1, a splicing factor is frequently mutated in refractory anemia with ring sideroblasts. Leukemia 2012; 26: 542\u2013545.","journal-title":"Leukemia"},{"key":"BFleu2016216_CR8","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1182\/blood-2011-09-377994","volume":"119","author":"MM Patnaik","year":"2012","unstructured":"Patnaik MM, Lasho TL, Hodnefield JM, Knudson RA, Ketterling RP, Garcia-Manero G et al. SF3B1 mutations are prevalent in myelodysplastic syndromes with ring sideroblasts but do not hold independent prognostic value. Blood 2012; 119: 569\u2013572.","journal-title":"Blood"},{"key":"BFleu2016216_CR9","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1002\/ajh.23373","volume":"88","author":"MM Patnaik","year":"2013","unstructured":"Patnaik MM, Lasho TL, Finke CM, Hanson CA, Hodnefield JM, Knudson RA et al. Spliceosome mutations involving SRSF2, SF3B1, and U2AF35 in chronic myelomonocytic leukemia: prevalence, clinical correlates, and prognostic relevance. Am J Hematol 2013; 88: 201\u2013206.","journal-title":"Am J Hematol"}],"container-title":["Leukemia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/leu2016216.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/leu2016216","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/leu2016216.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T16:14:14Z","timestamp":1648743254000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/leu2016216"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,1]]},"references-count":9,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["BFleu2016216"],"URL":"https:\/\/doi.org\/10.1038\/leu.2016.216","relation":{},"ISSN":["0887-6924","1476-5551"],"issn-type":[{"value":"0887-6924","type":"print"},{"value":"1476-5551","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,1]]},"assertion":[{"value":"1 August 2016","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}