{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:13:59Z","timestamp":1761844439710,"version":"build-2065373602"},"reference-count":50,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2015,7,1]],"date-time":"2015-07-01T00:00:00Z","timestamp":1435708800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,7,1]],"date-time":"2015-07-01T00:00:00Z","timestamp":1435708800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,27]],"date-time":"2022-01-27T00:00:00Z","timestamp":1643241600000},"content-version":"vor","delay-in-days":2402,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["mucosalimmunology.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Mucosal Immunology"],"published-print":{"date-parts":[[2015,7]]},"DOI":"10.1038\/mi.2014.119","type":"journal-article","created":{"date-parts":[[2014,12,10]],"date-time":"2014-12-10T08:16:51Z","timestamp":1418199411000},"page":"886-895","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Commensal enteric bacteria lipopolysaccharide impairs host defense against disseminated Candida albicans fungal infection"],"prefix":"10.1016","volume":"8","author":[{"given":"T T","family":"Jiang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Chaturvedi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J M","family":"Ertelt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Xin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D R","family":"Clark","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J M","family":"Kinder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S S","family":"Way","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1038\/mi.2014.119_bib1","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1038\/nature11551","article-title":"Reciprocal interactions of the intestinal microbiota and immune system","volume":"489","author":"Maynard","year":"2012","journal-title":"Nature"},{"key":"10.1038\/mi.2014.119_bib2","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1086\/514958","article-title":"Mechanisms and management of antibiotic-associated diarrhea","volume":"27","author":"H\u00f6genauer","year":"1998","journal-title":"Clin. Infect. Dis."},{"key":"10.1038\/mi.2014.119_bib3","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/nrgastro.2012.152","article-title":"The gut microbiota in IBD","volume":"9","author":"Manichanh","year":"2012","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1038\/mi.2014.119_bib4","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.cell.2007.08.017","article-title":"Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system","volume":"131","author":"Garrett","year":"2007","journal-title":"Cell"},{"key":"10.1038\/mi.2014.119_bib5","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1038\/nm.2087","article-title":"Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity","volume":"16","author":"Clarke","year":"2010","journal-title":"Nat. Med."},{"key":"10.1038\/mi.2014.119_bib6","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1038\/nature05414","article-title":"An obesity-associated gut microbiome with increased capacity for energy harvest","volume":"444","author":"Turnbaugh","year":"2006","journal-title":"Nature"},{"key":"10.1038\/mi.2014.119_bib7","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1038\/nature07336","article-title":"Innate immunity and intestinal microbiota in the development of Type 1 diabetes","volume":"455","author":"Wen","year":"2008","journal-title":"Nature"},{"key":"10.1038\/mi.2014.119_bib8","doi-asserted-by":"crossref","first-page":"11548","DOI":"10.1073\/pnas.1108924108","article-title":"Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice","volume":"108","author":"Kriegel","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1038\/mi.2014.119_bib9","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/j.immuni.2010.06.001","article-title":"Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells","volume":"32","author":"Wu","year":"2010","journal-title":"Immunity"},{"key":"10.1038\/mi.2014.119_bib10","doi-asserted-by":"crossref","first-page":"4615","DOI":"10.1073\/pnas.1000082107","article-title":"Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis","volume":"108","author":"Lee","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1038\/mi.2014.119_bib11","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.immuni.2012.04.011","article-title":"Commensal bacteria calibrate the activation threshold of innate antiviral immunity","volume":"37","author":"Abt","year":"2012","journal-title":"Immunity"},{"key":"10.1038\/mi.2014.119_bib12","doi-asserted-by":"crossref","first-page":"5354","DOI":"10.1073\/pnas.1019378108","article-title":"Microbiota regulates immune defense against respiratory tract influenza A virus infection","volume":"108","author":"Ichinohe","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1038\/mi.2014.119_bib13","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1053\/jhin.2002.1179","article-title":"Coronavirus-related nosocomial viral respiratory infections in a neonatal and paediatric intensive care unit: a prospective study","volume":"51","author":"Gagneur","year":"2002","journal-title":"J. Hosp. Infect."},{"key":"10.1038\/mi.2014.119_bib14","doi-asserted-by":"crossref","first-page":"S17","DOI":"10.1097\/00005176-200110002-00004","article-title":"Probiotics in the treatment and prevention of acute infectious diarrhea in infants and children: a systematic review of published randomized, double-blind, placebo-controlled trials","volume":"33","author":"Szajewska","year":"2001","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"key":"10.1038\/mi.2014.119_bib15","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1128\/iai.65.5.1748-1753.1997","article-title":"Gamma interferon is not essential in host defense against disseminated candidiasis in mice","volume":"65","author":"Qian","year":"1997","journal-title":"Infect. Immun."},{"key":"10.1038\/mi.2014.119_bib16","doi-asserted-by":"crossref","first-page":"5092","DOI":"10.1128\/iai.64.12.5092-5097.1996","article-title":"Importance of beta2-microglobulin in murine resistance to mucosal and systemic candidiasis","volume":"64","author":"Balish","year":"1996","journal-title":"Infect. Immun."},{"key":"10.1038\/mi.2014.119_bib17","doi-asserted-by":"crossref","first-page":"4918","DOI":"10.4049\/jimmunol.181.7.4918","article-title":"CD8 T cells utilize TRAIL to control influenza virus infection","volume":"181","author":"Brincks","year":"2008","journal-title":"J. Immunol."},{"key":"10.1038\/mi.2014.119_bib18","doi-asserted-by":"crossref","first-page":"e1002811","DOI":"10.1371\/journal.ppat.1002811","article-title":"Type I interferons promote fatal immunopathology by regulating inflammatory monocytes and neutrophils during Candida infections","volume":"8","author":"Majer","year":"2012","journal-title":"PLoS Pathog."},{"key":"10.1038\/mi.2014.119_bib19","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1016\/j.immuni.2013.05.010","article-title":"Interferon-\u03b2 production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans","volume":"38","author":"del Fresno","year":"2013","journal-title":"Immunity"},{"key":"10.1038\/mi.2014.119_bib20","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1086\/422329","article-title":"Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice","volume":"190","author":"Huang","year":"2004","journal-title":"J. Infect. Dis."},{"key":"10.1038\/mi.2014.119_bib21","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/j.1439-0507.2005.01121.x","article-title":"Temporal events in the intravenous challenge model for experimental Candida albicans infections in female mice","volume":"48","author":"MacCallum","year":"2005","journal-title":"Mycoses"},{"key":"10.1038\/mi.2014.119_bib22","doi-asserted-by":"crossref","first-page":"3487","DOI":"10.1099\/13500872-142-12-3487","article-title":"Neutrophil depletion increases susceptibility to systemic and vaginal candidiasis in mice, and reveals differences between brain and kidney in mechanisms of host resistance","volume":"142","author":"Fulurija","year":"1996","journal-title":"Microbiology"},{"key":"10.1038\/mi.2014.119_bib23","doi-asserted-by":"crossref","first-page":"2356","DOI":"10.4049\/jimmunol.158.5.2356","article-title":"An immunoregulatory role for neutrophils in CD4+ T helper subset selection in mice with candidiasis","volume":"158","author":"Romani","year":"1997","journal-title":"J. Immunol."},{"key":"10.1038\/mi.2014.119_bib24","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/ni.2797","article-title":"Activation of neutrophils by autocrine IL-17A-IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, ROR\u03b3t and dectin-2","volume":"15","author":"Taylor","year":"2014","journal-title":"Nat. Immunol."},{"key":"10.1038\/mi.2014.119_bib25","doi-asserted-by":"crossref","first-page":"3966","DOI":"10.1128\/IAI.05493-11","article-title":"Neutrophils produce interleukin 17A (IL-17A) in a dectin-1-and IL-23-dependent manner during invasive fungal infection","volume":"79","author":"Werner","year":"2011","journal-title":"Infect. Immun."},{"key":"10.1038\/mi.2014.119_bib26","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1172\/JCI115050","article-title":"Disparate effects of interferon-gamma and tumor necrosis factor-alpha on early neutrophil respiratory burst and fungicidal responses to Candida albicans hyphae in vitro","volume":"87","author":"Diamond","year":"1991","journal-title":"J. Clin. Invest."},{"key":"10.1038\/mi.2014.119_bib27","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1111\/j.1462-5822.2005.00659.x","article-title":"Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms","volume":"8","author":"Urban","year":"2006","journal-title":"Cell. Microbiol."},{"key":"10.1038\/mi.2014.119_bib28","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1083\/jcb.201006052","article-title":"Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps","volume":"191","author":"Papayannopoulos","year":"2010","journal-title":"J. Cell Biol."},{"key":"10.1038\/mi.2014.119_bib29","doi-asserted-by":"crossref","first-page":"e1000639","DOI":"10.1371\/journal.ppat.1000639","article-title":"Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against Candida albicans","volume":"5","author":"Urban","year":"2009","journal-title":"PLoS Pathog."},{"key":"10.1038\/mi.2014.119_bib30","doi-asserted-by":"crossref","first-page":"5293","DOI":"10.4049\/jimmunol.1101721","article-title":"Ly6G+ neutrophils are dispensable for defense against systemic Listeria monocytogenes infection","volume":"187","author":"Shi","year":"2011","journal-title":"J. Immunol."},{"key":"10.1038\/mi.2014.119_bib31","doi-asserted-by":"crossref","first-page":"e35","DOI":"10.1371\/journal.ppat.0040035","article-title":"Mucosal damage and neutropenia are required for Candida albicans dissemination","volume":"4","author":"Koh","year":"2008","journal-title":"PLoS Pathog."},{"key":"10.1038\/mi.2014.119_bib32","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.cell.2009.09.033","article-title":"Induction of intestinal Th17 cells by segmented filamentous bacteria","volume":"139","author":"Ivanov","year":"2009","journal-title":"Cell"},{"key":"10.1038\/mi.2014.119_bib33","doi-asserted-by":"crossref","first-page":"2917","DOI":"10.4049\/jimmunol.177.5.2917","article-title":"Addition of a prominent epitope affects influenza A virus-specific CD8+ T cell immunodominance hierarchies when antigen is limiting","volume":"177","author":"Jenkins","year":"2006","journal-title":"J. Immunol."},{"key":"10.1038\/mi.2014.119_bib34","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.immuni.2011.06.005","article-title":"Skin-resident murine dendritic cell subsets promote distinct and opposing antigen-specific T helper cell responses","volume":"35","author":"Igy\u00e1rt\u00f3","year":"2011","journal-title":"Immunity"},{"key":"10.1038\/mi.2014.119_bib35","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1126\/science.1210718","article-title":"Successful transmission of a retrovirus depends on the commensal microbiota","volume":"334","author":"Kane","year":"2011","journal-title":"Science"},{"key":"10.1038\/mi.2014.119_bib36","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1126\/science.1211057","article-title":"Intestinal microbiota promote enteric virus replication and systemic pathogenesis","volume":"334","author":"Kuss","year":"2011","journal-title":"Science"},{"key":"10.1038\/mi.2014.119_bib37","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1084\/jem.20081463","article-title":"Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis","volume":"206","author":"Conti","year":"2009","journal-title":"J. Exp. Med."},{"key":"10.1038\/mi.2014.119_bib38","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.cell.2005.05.007","article-title":"An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system","volume":"122","author":"Mazmanian","year":"2005","journal-title":"Cell"},{"key":"10.1038\/mi.2014.119_bib39","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1086\/504324","article-title":"Oral supplementation with Lactobacillus casei subspecies rhamnosus prevents enteric colonization by Candida species in preterm neonates: a randomized study","volume":"42","author":"Manzoni","year":"2006","journal-title":"Clin. Infect. Dis."},{"key":"10.1038\/mi.2014.119_bib40","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1007\/s10096-002-0822-1","article-title":"Candidemia at a tertiary-care hospital: epidemiology, treatment, clinical outcome and risk factors for death","volume":"21","author":"Viudes","year":"2002","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"10.1038\/mi.2014.119_bib41","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1086\/513663","article-title":"The epidemiology of hematogenous candidiasis caused by different Candida species","volume":"24","author":"Abi-Said","year":"1997","journal-title":"Clin. Infect. Dis."},{"key":"10.1038\/mi.2014.119_bib42","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1086\/376906","article-title":"A prospective observational study of candidemia: epidemiology, therapy, and influences on mortality in hospitalized adult and pediatric patients","volume":"37","author":"Pappas","year":"2003","journal-title":"Clin. Infect. Dis."},{"key":"10.1038\/mi.2014.119_bib43","doi-asserted-by":"crossref","first-page":"e1002865","DOI":"10.1371\/journal.ppat.1002865","article-title":"Chemokine receptor Ccr1 drives neutrophil-mediated kidney immunopathology and mortality in invasive candidiasis","volume":"8","author":"Lionakis","year":"2012","journal-title":"PLoS Pathog."},{"key":"10.1038\/mi.2014.119_bib44","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.cell.2013.06.013","article-title":"A systems analysis identifies a feedforward inflammatory circuit leading to lethal influenza infection","volume":"154","author":"Brandes","year":"2013","journal-title":"Cell"},{"key":"10.1038\/mi.2014.119_bib45","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1086\/599039","article-title":"Epidemiology and outcomes of candidemia in 2019 patients: data from the prospective antifungal therapy alliance registry","volume":"48","author":"Horn","year":"2009","journal-title":"Clin. Infect. Dis."},{"key":"10.1038\/mi.2014.119_bib46","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/j.1365-2567.2008.03017.x","article-title":"Interleukin-17 in host defence against bacterial, mycobacterial and fungal pathogens","volume":"126","author":"Curtis","year":"2009","journal-title":"Immunology"},{"key":"10.1038\/mi.2014.119_bib47","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1128\/jcm.26.3.429-432.1988","article-title":"Risk factors for candidemia in cancer patients: a case-control study","volume":"26","author":"Karabinis","year":"1988","journal-title":"J. Clin. Microbiol."},{"key":"10.1038\/mi.2014.119_bib48","first-page":"391","article-title":"Influence of antimicrobial drugs on segmented filamentous bacteria in the ileum of mice","volume":"4","author":"Klaasen","year":"1991","journal-title":"Microb. Ecol. Health Dis."},{"key":"10.1038\/mi.2014.119_bib49","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.4049\/jimmunol.163.3.1498","article-title":"Increased susceptibility of TNF-\u03b1 lymphotoxin-\u03b1 double knockout mice to systemic candidiasis through impaired recruitment of neutrophils and phagocytosis of Candida albicans","volume":"163","author":"Netea","year":"1999","journal-title":"J. Immunol."},{"key":"10.1038\/mi.2014.119_bib50","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1007\/BF00368326","article-title":"Dihydrorhodamine 123: a new flow cytometric indicator for respiratory burst activity in neutrophil granulocytes","volume":"75","author":"Rothe","year":"1988","journal-title":"Naturwissenschaften"}],"container-title":["Mucosal Immunology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/mi2014119.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/mi2014119","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1933021922009722?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1933021922009722?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/mi2014119.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T13:22:58Z","timestamp":1761830578000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1933021922009722"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7]]},"references-count":50,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["S1933021922009722"],"URL":"https:\/\/doi.org\/10.1038\/mi.2014.119","relation":{},"ISSN":["1933-0219"],"issn-type":[{"type":"print","value":"1933-0219"}],"subject":[],"published":{"date-parts":[[2015,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Commensal enteric bacteria lipopolysaccharide impairs host defense against disseminated Candida albicans fungal infection","name":"articletitle","label":"Article Title"},{"value":"Mucosal Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/mi.2014.119","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 \u00a9 Society for Mucosal Immunology. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}