{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T01:31:04Z","timestamp":1792459864623,"version":"4.5.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T00:00:00Z","timestamp":1673395200000},"content-version":"vor","delay-in-days":4577,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["mp.uscap.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Modern Pathology"],"published-print":{"date-parts":[[2010,7]]},"DOI":"10.1038\/modpathol.2010.76","type":"journal-article","created":{"date-parts":[[2010,3,26]],"date-time":"2010-03-26T11:05:53Z","timestamp":1269601553000},"page":"909-920","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":53,"title":["Simple karyotype and bcl-6 expression predict a diagnosis of Burkitt lymphoma and better survival in IG-MYC rearranged high-grade B-cell lymphomas"],"prefix":"10.1016","volume":"23","author":[{"given":"Adam C","family":"Seegmiller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolando","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atousa","family":"Maleki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitin J","family":"Karandikar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weina","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/modpathol.2010.76_bib1","series-title":"World Health Organization Classification of Tumors of Haematopoieitc and Lymphoid Tissues","first-page":"262","article-title":"Burkitt lymphoma","author":"Leoncini","year":"2008"},{"key":"10.1038\/modpathol.2010.76_bib2","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1111\/j.1365-2141.2006.06194.x","article-title":"Diagnosis of Burkitt lymphoma in due time: a practical approach","volume":"134","author":"Cogliatti","year":"2006","journal-title":"Br J Haematol"},{"key":"10.1038\/modpathol.2010.76_bib3","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1097\/01.pas.0000168176.71405.e5","article-title":"Clinical, immunophenotypic, and genetic analysis of adult lymphomas with morphologic features of Burkitt lymphoma","volume":"29","author":"Haralambieva","year":"2005","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/modpathol.2010.76_bib4","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1097\/01.pas.0000180442.87022.08","article-title":"Adult B-cell lymphomas with burkitt-like morphology are phenotypically and genotypically heterogeneous with aggressive clinical behavior","volume":"29","author":"McClure","year":"2005","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/modpathol.2010.76_bib5","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1097\/PAS.0b013e3180959e09","article-title":"Characteristic expression patterns of TCL1, CD38, and CD44 identify aggressive lymphomas harboring a MYC translocation","volume":"32","author":"Rodig","year":"2008","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/modpathol.2010.76_bib6","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/modpathol.3800500","article-title":"Lymphoid neoplasms associated with concurrent t(14;18) and 8q24\/c-MYC translocation generally have a poor prognosis","volume":"19","author":"Kanungo","year":"2006","journal-title":"Mod Pathol"},{"key":"10.1038\/modpathol.2010.76_bib7","doi-asserted-by":"crossref","first-page":"3713","DOI":"10.1182\/blood.V97.12.3713","article-title":"The Burkitt-like lymphomas: a southwest oncology group study delineating phenotypic, genotypic, and clinical features","volume":"97","author":"Braziel","year":"2001","journal-title":"Blood"},{"key":"10.1038\/modpathol.2010.76_bib8","series-title":"World Health Organization Classification of Tumors of Haematopoieitc and Lymphoid Tissues","first-page":"265","article-title":"B-cell lymphoma, unclassifiable, with feature intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma","author":"Kluin","year":"2008"},{"key":"10.1038\/modpathol.2010.76_bib9","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1002\/cncr.22089","article-title":"Secondary chromosomal abnormalities predict outcome in pediatric and adult high-stage Burkitt lymphoma","volume":"107","author":"Onciu","year":"2006","journal-title":"Cancer"},{"key":"10.1038\/modpathol.2010.76_bib10","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1097\/00043426-200403000-00006","article-title":"Chromosome abnormalities may correlate with prognosis in Burkitt\/Burkitt-like lymphomas of children and adolescents: a report from Children's Cancer Group Study CCG-E08","volume":"26","author":"Lones","year":"2004","journal-title":"J Pediatr Hematol Oncol"},{"key":"10.1038\/modpathol.2010.76_bib11","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/leu.2008.312","article-title":"Specific cytogenetic abnormalities are associated with a significantly inferior outcome in children and adolescents with mature B-cell non-Hodgkin's lymphoma: results of the FAB\/LMB 96 International Study","volume":"23","author":"Poirel","year":"2009","journal-title":"Leukemia"},{"key":"10.1038\/modpathol.2010.76_bib12","doi-asserted-by":"crossref","first-page":"574","DOI":"10.3109\/07357900009012197","article-title":"Burkitt's lymphoma: molecular pathogenesis and treatment","volume":"18","author":"Bishop","year":"2000","journal-title":"Cancer Invest"},{"key":"10.1038\/modpathol.2010.76_bib13","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1056\/NEJMoa055759","article-title":"Molecular diagnosis of Burkitt's lymphoma","volume":"354","author":"Dave","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1038\/modpathol.2010.76_bib14","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.1056\/NEJMoa055351","article-title":"A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling","volume":"354","author":"Hummel","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1038\/modpathol.2010.76_bib15","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1097\/01.pai.0000129055.93199.2b","article-title":"The t(14;18) in diffuse large B-cell lymphoma: correlation with germinal center-associated markers and clinical features","volume":"13","author":"Xu","year":"2005","journal-title":"Appl Immunohistochem Mol Morphol"},{"key":"10.1038\/modpathol.2010.76_bib16","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1309\/6UGDU03VVD0L98LQ","article-title":"Characterization of incidentally identified minute clonal B-lymphocyte populations in peripheral blood and bone marrow","volume":"122","author":"Chen","year":"2004","journal-title":"Am J Clin Pathol"},{"key":"10.1038\/modpathol.2010.76_bib17","series-title":"ISCN 2005: An International System for Human Cytogenetic Nomenclature","author":"Shaffer","year":"2005"},{"key":"10.1038\/modpathol.2010.76_bib18","unstructured":"Stein H, Harris NL, Campo E . Plasmablastic lymphoma. In: Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW (eds). World Health Organization Classification of Tumors of Haematopoieitc and Lymphoid Tissues 2008, pp 256\u2013257."},{"key":"10.1038\/modpathol.2010.76_bib19","unstructured":"Stein H, Warnke RA, Chan WC, et al. Diffuse large B-cell lymphoma, not otherwise specified. In: Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW (eds). World Health Organization Classification of Tumors of Haematopoieitc and Lymphoid Tissues 2008, p. 233\u2013237."},{"key":"10.1038\/modpathol.2010.76_bib20","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1080\/10428190902930470","article-title":"Bright CD38 expression is an indicator of MYC rearrangement","volume":"50","author":"Maleki","year":"2009","journal-title":"Leuk Lymphoma"},{"key":"10.1038\/modpathol.2010.76_bib21","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1023\/A:1008375931236","article-title":"The World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues","volume":"10","author":"Harris","year":"1999","journal-title":"Ann Oncol"},{"key":"10.1038\/modpathol.2010.76_bib22","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1002\/path.2410","article-title":"MYC translocation-negative classical Burkitt lymphoma cases: an alternative pathogenetic mechanism involving miRNA deregulation","volume":"216","author":"Leucci","year":"2008","journal-title":"J Pathol"},{"key":"10.1038\/modpathol.2010.76_bib23","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/leu.2008.281","article-title":"Translocations involving 8q24 in Burkitt lymphoma and other malignant lymphomas: a historical review of cytogenetics in the light of todays knowledge","volume":"23","author":"Boerma","year":"2009","journal-title":"Leukemia"},{"key":"10.1038\/modpathol.2010.76_bib24","doi-asserted-by":"crossref","first-page":"2273","DOI":"10.1182\/blood-2009-03-212191","article-title":"Lymphomas with concurrent BCL2 and MYC translocations: the critical factors associated with survival","volume":"114","author":"Johnson","year":"2009","journal-title":"Blood"},{"key":"10.1038\/modpathol.2010.76_bib25","doi-asserted-by":"crossref","first-page":"3533","DOI":"10.1182\/blood-2009-05-220095","article-title":"MYC gene re-arrangements are associated with a poor prognosis in diffuse large B-cell lymphoma patients treated with R-CHOP chemotherapy","volume":"114","author":"Savage","year":"2009","journal-title":"Blood"},{"key":"10.1038\/modpathol.2010.76_bib26","doi-asserted-by":"crossref","first-page":"3152","DOI":"10.1182\/blood.V92.9.3152","article-title":"Clinical relevance of BCL2, BCL6, and MYC rearrangements in diffuse large B-cell lymphoma","volume":"92","author":"Kramer","year":"1998","journal-title":"Blood"},{"key":"10.1038\/modpathol.2010.76_bib27","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1182\/blood.V77.5.1057.1057","article-title":"MYC rearrangement and translocations involving band 8q24 in diffuse large cell lymphomas","volume":"77","author":"Ladanyi","year":"1991","journal-title":"Blood"},{"key":"10.1038\/modpathol.2010.76_bib28","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1309\/AJCPFUR1BK0UODTS","article-title":"Plasmablastic lymphomas with MYC\/IgH rearrangement: report of three cases and review of the literature","volume":"132","author":"Bogusz","year":"2009","journal-title":"Am J Clin Path"},{"key":"10.1038\/modpathol.2010.76_bib29","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1200\/JCO.2000.18.3.510","article-title":"Molecular and clinical features of non-Burkitt's, diffuse large-cell lymphoma of B-cell type associated with the c-MYC\/immunoglobulin heavy-chain fusion gene","volume":"18","author":"Akasaka","year":"2000","journal-title":"J Clin Oncol"},{"key":"10.1038\/modpathol.2010.76_bib30","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.3324\/haematol.13071","article-title":"Chromosomal alterations detected by comparative genomic hybridization in subgroups of gene expression-defined Burkitt's lymphoma","volume":"93","author":"Salaverria","year":"2008","journal-title":"Haematologica"},{"key":"10.1038\/modpathol.2010.76_bib31","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1182\/blood-2008-01-136465","article-title":"Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials","volume":"112","author":"Klapper","year":"2008","journal-title":"Blood"}],"container-title":["Modern Pathology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/modpathol201076.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/modpathol201076","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0893395222026795?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0893395222026795?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/modpathol201076.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T01:02:21Z","timestamp":1760230941000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0893395222026795"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7]]},"references-count":31,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["S0893395222026795"],"URL":"https:\/\/doi.org\/10.1038\/modpathol.2010.76","relation":{},"ISSN":["0893-3952"],"issn-type":[{"value":"0893-3952","type":"print"}],"subject":[],"published":{"date-parts":[[2010,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Simple karyotype and bcl-6 expression predict a diagnosis of Burkitt lymphoma and better survival in IG-MYC rearranged high-grade B-cell lymphomas","name":"articletitle","label":"Article Title"},{"value":"Modern Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/modpathol.2010.76","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2010 United States & Canadian Academy of Pathology.","name":"copyright","label":"Copyright"}]}}