{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T10:37:07Z","timestamp":1792147027772,"version":"4.4.0"},"reference-count":48,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2004,7,1]],"date-time":"2004-07-01T00:00:00Z","timestamp":1088640000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,7,1]],"date-time":"2004-07-01T00:00:00Z","timestamp":1088640000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T00:00:00Z","timestamp":1673395200000},"content-version":"vor","delay-in-days":6768,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["mp.uscap.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Modern Pathology"],"published-print":{"date-parts":[[2004,7]]},"DOI":"10.1038\/modpathol.3800129","type":"journal-article","created":{"date-parts":[[2004,4,9]],"date-time":"2004-04-09T06:13:15Z","timestamp":1081491195000},"page":"840-846","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["TIA-1 expression in hairy cell leukemia"],"prefix":"10.1016","volume":"17","author":[{"given":"Naoyoshi","family":"Mori","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiko Idate","family":"Murakami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoko","family":"Shimada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachiko","family":"Iwamizu-Watanabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoriko","family":"Yamashita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuichi","family":"Hasegawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Kojima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiro","family":"Nagasawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/modpathol.3800129_bib1","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/0167-5699(91)90145-J","article-title":"Expression of perforin and granzymes in vivo: potential diagnostic markers for activated cytotoxic cells","volume":"12","author":"Griffiths","year":"1991","journal-title":"Immunol Today"},{"key":"10.1038\/modpathol.3800129_bib2","first-page":"3699","article-title":"Structure, tissue distribution and genomic organization of the murine RRM-type RNA binding proteins TIA-1 and TIAR","volume":"21","author":"Beck","year":"1993","journal-title":"Nucleic Acids Res"},{"key":"10.1038\/modpathol.3800129_bib3","doi-asserted-by":"crossref","first-page":"8681","DOI":"10.1073\/pnas.89.18.8681","article-title":"Identification and functional characterization of a TIA-1-related protein","volume":"89","author":"Kawakami","year":"1992","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/modpathol.3800129_bib4","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/0092-8674(91)90536-8","article-title":"A polyadenylate binding protein localized to the granules of cytolytic lymphocytes induces DNA fragmentation in target cells","volume":"67","author":"Tian","year":"1991","journal-title":"Cell"},{"key":"10.1038\/modpathol.3800129_bib5","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0165-2478(92)90144-D","article-title":"Perforin is expressed in CTL populations generated in vivo","volume":"31","author":"Takeuchi","year":"1992","journal-title":"Immunol Lett"},{"key":"10.1038\/modpathol.3800129_bib6","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1073\/pnas.93.2.685","article-title":"Characterization of GMP-17, a granule membrane protein that moves to the plasma membrane of natural killer cells following target cell recognition","volume":"93","author":"Medley","year":"1996","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1038\/modpathol.3800129_bib7","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1002\/jlb.65.1.109","article-title":"Significant expression of G-CSF-induced gene-1(GIG-1)protein in myeloid cells and NK cells","volume":"65","author":"Shimane","year":"1999","journal-title":"J Leukoc Biol"},{"key":"10.1038\/modpathol.3800129_bib8","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1002\/(SICI)1096-9896(199712)183:4<432::AID-PATH942>3.0.CO;2-4","article-title":"Cytotoxic protein expression in natural killer cell lymphomas and in \u03b1\u03b2 \u03b3\u03b4 peripheral T-cell lymphomas","volume":"183","author":"Boulland","year":"1997","journal-title":"J Pathol"},{"key":"10.1038\/modpathol.3800129_bib9","first-page":"1893","article-title":"TIA-1 expression in lymphoid neoplasms. Identification of subsets with cytotoxic T lymphocyte or natural killer cell differentiation","volume":"150","author":"Felger","year":"1997","journal-title":"Am J Pathol"},{"key":"10.1038\/modpathol.3800129_bib10","first-page":"313","article-title":"Perforin and granzyme expression in cytotoxic T-cell lymphomas","volume":"11","author":"Yamashita","year":"1998","journal-title":"Mod Pathol"},{"key":"10.1038\/modpathol.3800129_bib11","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1097\/00000478-200012000-00006","article-title":"Lennert's lymphoma. A variant of cytotoxic T-cell lymphoma?","volume":"24","author":"Yamashita","year":"2000","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/modpathol.3800129_bib12","first-page":"699","article-title":"Expression of perforin in nasal lymphoma. Additional evidence of its natural killer cell derivation","volume":"149","author":"Mori","year":"1996","journal-title":"Am J Pathol"},{"key":"10.1038\/modpathol.3800129_bib13","doi-asserted-by":"crossref","first-page":"4501","DOI":"10.1182\/blood.V89.12.4501","article-title":"Nonnasal lymphoma expressing the natural killer cell marker CD56: a clinicopathologic study of 49 cases of an uncommon aggressive neoplasm","volume":"86","author":"Chan","year":"1997","journal-title":"Blood"},{"key":"10.1038\/modpathol.3800129_bib14","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1046\/j.1365-2559.2000.00936.x","article-title":"Lymphomatous features of aggressive NK cell leukemia\/lymphoma with massive necrosis, haemophagocytosis and EB virus infection","volume":"37","author":"Mori","year":"2000","journal-title":"Histopathology"},{"key":"10.1038\/modpathol.3800129_bib15","doi-asserted-by":"crossref","first-page":"4265","DOI":"10.1182\/blood.V88.11.4265.bloodjournal88114265","article-title":"Hepatosplenic T-cell lymphoma: a distinct clinicopathologic entity of cytotoxic \u03b3\u03b4 T-cell origin","volume":"88","author":"Cooke","year":"1996","journal-title":"Blood"},{"key":"10.1038\/modpathol.3800129_bib16","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1309\/YTTC-F55W-K9CP-EPX5","article-title":"Hepatosplenic gamma\u2013delta T-cell lymphoma as a late-onset posttransplant lymphoproliferative disorder in renal transplant recipients","volume":"113","author":"Wu","year":"2000","journal-title":"Am J Clin Pathol"},{"key":"10.1038\/modpathol.3800129_bib17","first-page":"617","article-title":"Expression of the alpha\/beta and gamma\/delta T-cell receptors in 57 cases of peripheral T-cell lymphomas. Identification of a subset of \u03b3\/\u03b4 T-cell lymphomas","volume":"137","author":"Gaulard","year":"1990","journal-title":"Am J Pathol"},{"key":"10.1038\/modpathol.3800129_bib18","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1097\/00000478-199101000-00002","article-title":"T-cell lymphoma involving subcutaneous tissue. A clinicopathologic entity commonly associated with hemophagocytic syndrome","volume":"15","author":"Gonzalez","year":"1991","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/modpathol.3800129_bib19","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1097\/00000478-199807000-00010","article-title":"Subcutaneous panniculitis-like T-cell lymphoma: clinicopathologic,immunophenotypic, and genotypic analysis of alpha\/beta and gamma\/delta subtypes","volume":"22","author":"Salhany","year":"1998","journal-title":"Am J Surg Pathol"},{"key":"10.1038\/modpathol.3800129_bib20","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1016\/S0002-9440(10)65736-7","article-title":"Most CD56+ intestinal lymphomas are CD8+CD5\u2212 T-cell lymphomas of monomorphic small to medium size histology","volume":"153","author":"Chott","year":"1998","journal-title":"Am J Pathol"},{"key":"10.1038\/modpathol.3800129_bib21","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1182\/blood.V89.3.980","article-title":"Cytotoxic cell antigen expression in anaplastic large cell lymphomas of T- and null-cell type and Hodgkin's disease: evidence for distinct cellular origin","volume":"89","author":"Krenacs","year":"1997","journal-title":"Blood"},{"key":"10.1038\/modpathol.3800129_bib22","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1177\/22.12.1077","article-title":"Periodate-lysine-paraformaldehyde fixative: a new fixative for immunoelectron microscopy","volume":"22","author":"McLean","year":"1974","journal-title":"J Histochem Cytochem"},{"key":"10.1038\/modpathol.3800129_bib23","first-page":"53","article-title":"An ultrastructural study with enzyme-labeled antibody technique on immunoglobulin containing cells in human tonsils, especially in germinal centers","volume":"28","author":"Tsunoda","year":"1978","journal-title":"Acta Pathol Jpn"},{"key":"10.1038\/modpathol.3800129_bib24","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1177\/29.4.6166661","article-title":"Use of avidin\u2013biotin\u2013peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody(PAP) procedures","volume":"29","author":"Hsu","year":"1981","journal-title":"J Histochem Cytochem"},{"key":"10.1038\/modpathol.3800129_bib25","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1182\/blood.V13.7.609.609","article-title":"Leukemic reticuloendotheliosis","volume":"13","author":"Bouroncle","year":"1958","journal-title":"Blood"},{"key":"10.1038\/modpathol.3800129_bib26","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1056\/NEJM197102182840704","article-title":"Tartrate-resistant acid phosphatase isoenzyme in the reticulum cells of leukemic reticuloendotheliosis","volume":"284","author":"Yam","year":"1971","journal-title":"N Engl J Med"},{"key":"10.1038\/modpathol.3800129_bib27","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/0002-9343(74)90775-X","article-title":"Leukemic reticuloendotheliosis: Presence of a receptor for cytophilic antibody","volume":"57","author":"Jaffe","year":"1974","journal-title":"Am J Med"},{"key":"10.1038\/modpathol.3800129_bib28","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/0002-9343(74)90776-1","article-title":"Leukemic reticuloendotheliosis. A clinicopathologic study with review of the literature","volume":"157","author":"Katayama","year":"1974","journal-title":"Am J Med"},{"key":"10.1038\/modpathol.3800129_bib29","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1002\/1097-0142(197411)34:5<1813::AID-CNCR2820340532>3.0.CO;2-6","article-title":"Leukemic reticuloendotheliosis","volume":"34","author":"Naeim","year":"1974","journal-title":"Cancer"},{"key":"10.1038\/modpathol.3800129_bib30","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/0002-9343(75)90400-3","article-title":"Leukemic reticuloendotheliosis. A study of the origin of the malignant cell","volume":"59","author":"King","year":"1975","journal-title":"Am J Med"},{"key":"10.1038\/modpathol.3800129_bib31","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1093\/ajcp\/68.2.268","article-title":"Reassesment of a cytochemical test for differential diagnosis of leukemic reticuloendotheliosis","volume":"68","author":"Katayama","year":"1977","journal-title":"Am J Clin Pathol"},{"key":"10.1038\/modpathol.3800129_bib32","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1182\/blood.V61.2.349.349","article-title":"Response to splenectomy in 65 patients with hairy cell leukemia: an evaluation of spleen weight and bone marrow involvement","volume":"61","author":"Golomb","year":"1983","journal-title":"Blood"},{"key":"10.1038\/modpathol.3800129_bib33","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1182\/blood.V27.2.199.199","article-title":"Hairy cells in blood in lymphoreticular neoplastic disease and flagellated cells of normal lymph nodes","volume":"27","author":"Schrek","year":"1966","journal-title":"Blood"},{"key":"10.1038\/modpathol.3800129_bib34","series-title":"Neoplastic Hematopathology","first-page":"1531","article-title":"Hairy cell leukemia and related disorders","author":"Bitter","year":"2001"},{"key":"10.1038\/modpathol.3800129_bib35","first-page":"138","article-title":"Hairy cell leukemia","author":"Foucar","year":"2001","journal-title":"World Health Organization Classification of Tumors. Tumors of Haematopoietic and Lymphoid Tissues"},{"key":"10.1038\/modpathol.3800129_bib36","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1093\/ajcp\/67.5.415","article-title":"Splenic pseudosinuses and hepatic angiomatous lesions. Distinctive features of hairy cell leukemia","volume":"67","author":"Nanba","year":"1977","journal-title":"Am J Clin Pathol"},{"key":"10.1038\/modpathol.3800129_bib37","first-page":"181","article-title":"Predominance of a distinct subtype of hairy cell leukemia in Japan","volume":"7","author":"Machii","year":"1993","journal-title":"Leukemia"},{"key":"10.1038\/modpathol.3800129_bib38","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/0925-5710(96)00497-5","article-title":"Early age onset of hairy cell leukemia presenting with leukocytosis","volume":"64","author":"Shibayama","year":"1996","journal-title":"Int J Hematol"},{"key":"10.1038\/modpathol.3800129_bib39","first-page":"1390","article-title":"Immunophenotypic features and configuration of immunoglobulin genes in hairy cell leukemia-Japanese variant","volume":"10","author":"Yamaguchi","year":"1996","journal-title":"Leukemia"},{"key":"10.1038\/modpathol.3800129_bib40","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1182\/blood.V76.1.157.157","article-title":"A variant of hairy cell leukemia resistant to \u03b1-interferon. Clinical and phenotypic characteristics of 17 patients","volume":"76","author":"Sainati","year":"1990","journal-title":"Blood"},{"key":"10.1038\/modpathol.3800129_bib41","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1093\/ajcp\/90.3.250","article-title":"Evaluation of LeuM5(CD11c) in hairy cell leukemia by the alkaline phosphatase anti-alkaline phosphatase technique","volume":"90","author":"Vardiman","year":"1988","journal-title":"Am J Clin Pathol"},{"key":"10.1038\/modpathol.3800129_bib42","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1182\/blood.V65.4.974.974","article-title":"The monoclonal antibodies \u03b1S-HCL1(\u03b1Leu14) and \u03b1S-HCL3(\u03b1LeuM5) allow the diagnosis of hairy cell leukemia","volume":"65","author":"Schwarting","year":"1985","journal-title":"Blood"},{"key":"10.1038\/modpathol.3800129_bib43","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1093\/ajcp\/80.4.421","article-title":"Hairy cell leukemia: a B cell neoplasm with a unique antigenic phenotype","volume":"80","author":"Hsu","year":"1983","journal-title":"Am J Clin Pathol"},{"key":"10.1038\/modpathol.3800129_bib44","first-page":"141","article-title":"Chronic lymphoid leukemias and lymphoproliferative disorders","volume":"12","author":"Foucar","year":"1999","journal-title":"Mod Pathol"},{"key":"10.1038\/modpathol.3800129_bib45","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1182\/blood.V94.3.1077.415k06_1077_1085","article-title":"Basic fibroblast growth factor is expressed by CD19\/CD11c-positive cells in hairy cell leukemia","volume":"94","author":"Gruber","year":"1999","journal-title":"Blood"},{"key":"10.1038\/modpathol.3800129_bib46","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1182\/blood-2002-12-3737","article-title":"The role of autocrine FGF-2 in the distinctive bone marrow fibrosis of hairy cell leukemia (HCL)","volume":"102","author":"Aziz","year":"2003","journal-title":"Blood"},{"key":"10.1038\/modpathol.3800129_bib47","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1002\/ajh.2830380106","article-title":"Hemopoietic inhibition in hairy cell leukemia","volume":"38","author":"Janckila","year":"1991","journal-title":"Am J Hematol"},{"key":"10.1038\/modpathol.3800129_bib48","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0145-2126(01)00100-X","article-title":"Interferon-alpha 2b and vesnarinone influence levels of tumor necrosis factor-alpha, apoptosis, or interleukin 6 in ESKOL, a hairy cell leukemic cell line. A potential cytokine and oncogene relationship regulating apoptosis is suggested","volume":"26","author":"Khalaf","year":"2002","journal-title":"Leuk Res"}],"container-title":["Modern Pathology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/3800129.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/3800129","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0893395222043393?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0893395222043393?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/3800129.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T01:18:39Z","timestamp":1760231919000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0893395222043393"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,7]]},"references-count":48,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2004,7]]}},"alternative-id":["S0893395222043393"],"URL":"https:\/\/doi.org\/10.1038\/modpathol.3800129","relation":{},"ISSN":["0893-3952"],"issn-type":[{"value":"0893-3952","type":"print"}],"subject":[],"published":{"date-parts":[[2004,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"TIA-1 expression in hairy cell leukemia","name":"articletitle","label":"Article Title"},{"value":"Modern Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/modpathol.3800129","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2004 United States & Canadian Academy of Pathology.","name":"copyright","label":"Copyright"}]}}