{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T12:10:44Z","timestamp":1777637444874,"version":"3.51.4"},"reference-count":16,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T00:00:00Z","timestamp":1673395200000},"content-version":"vor","delay-in-days":5458,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["mp.uscap.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Modern Pathology"],"published-print":{"date-parts":[[2008,2]]},"DOI":"10.1038\/modpathol.3800986","type":"journal-article","created":{"date-parts":[[2007,12,14]],"date-time":"2007-12-14T12:38:42Z","timestamp":1197635922000},"page":"125-130","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":78,"title":["Podoplanin is a useful diagnostic marker for epithelioid hemangioendothelioma of the liver"],"prefix":"10.1016","volume":"21","author":[{"given":"Takahiko","family":"Fujii","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoh","family":"Zen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasunori","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motoko","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mio","family":"Enomae","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Minato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinji","family":"Masuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Uehara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsutomu","family":"Katsuyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuni","family":"Nakanuma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1038\/modpathol.3800986_bib1","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/sj.bjc.6690393","article-title":"Characterization and distribution of an oncofetal antigen (M2A antigen) expressed on testicular germ cell tumours","volume":"80","author":"Marks","year":"1999","journal-title":"Br J Cancer"},{"key":"10.1038\/modpathol.3800986_bib2","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/S0002-9440(10)62311-5","article-title":"Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors","volume":"166","author":"Schacht","year":"2005","journal-title":"Am J Pathol"},{"key":"10.1038\/modpathol.3800986_bib3","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1038\/sj.bjc.6603152","article-title":"Distinguishing blood and lymph vessel invasion in breast cancer: a prospective immunohistochemical study","volume":"94","author":"Van den Eynden","year":"2006","journal-title":"Br J Cancer"},{"key":"10.1038\/modpathol.3800986_bib4","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/01.pap.0000213007.48479.94","article-title":"Podoplanin: a novel diagnostic immunohistochemical marker","volume":"13","author":"Ord\u00f3\u00f1ez","year":"2006","journal-title":"Adv Anat Pathol"},{"key":"10.1038\/modpathol.3800986_bib5","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1111\/j.1600-0560.2006.00461.x","article-title":"Usefulness of D2-40 immunohistochemistry for differentiation between kaposiform hemangioendothelioma and tufted angioma","volume":"33","author":"Arai","year":"2006","journal-title":"J Cutan Pathol"},{"key":"10.1038\/modpathol.3800986_bib6","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S0002-9440(10)65285-6","article-title":"Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: podoplanin as a specific marker for lymphatic endothelium","volume":"154","author":"Breiteneder-Geleff","year":"1999","journal-title":"Am J Pathol"},{"key":"10.1038\/modpathol.3800986_bib7","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1038\/modpathol.3800444","article-title":"D2-40 immunohistochemical analysis of pediatric vascular tumors reveals positivity in kaposiform hemangioendothelioma","volume":"18","author":"Debelenko","year":"2005","journal-title":"Mod Pathol"},{"key":"10.1038\/modpathol.3800986_bib8","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1111\/j.0303-6987.2004.00192.x","article-title":"Hobnail hemangiomas (targetoid hemosiderotic hemangiomas) are true lymphangiomas","volume":"31","author":"Franke","year":"2004","journal-title":"J Cutan Pathol"},{"key":"10.1038\/modpathol.3800986_bib9","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1111\/j.1365-2559.2005.02098.x","article-title":"Expression of D2-40 in lymphatic endothelium of normal tissues and in vascular tumours","volume":"46","author":"Fukunaga","year":"2005","journal-title":"Histopathology"},{"key":"10.1038\/modpathol.3800986_bib10","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1038\/modpathol.3880543","article-title":"Monoclonal antibody D2-40, a new marker of lymphatic endothelium, reacts with Kaposi's sarcoma and a subset of angiosarcomas","volume":"15","author":"Kahn","year":"2002","journal-title":"Mod Pathol"},{"key":"10.1038\/modpathol.3800986_bib11","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1002\/1097-0142(19820901)50:5<970::AID-CNCR2820500527>3.0.CO;2-Z","article-title":"Epithelioid hemangioendothelioma: a vascular tumor often mistaken for a carcinoma","volume":"50","author":"Weiss","year":"1982","journal-title":"Cancer"},{"key":"10.1038\/modpathol.3800986_bib12","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/S0046-8177(84)80145-8","article-title":"Epithelioid hemangioendothelioma of the liver: a clinicopathologic and follow-up study of 32 cases","volume":"15","author":"Ishak","year":"1984","journal-title":"Hum Pathol"},{"key":"10.1038\/modpathol.3800986_bib13","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/0016-5085(89)90675-6","article-title":"Hepatic epithelioid hemangioendothelioma in primary biliary cirrhosis","volume":"97","author":"Terada","year":"1989","journal-title":"Gastroenterology"},{"key":"10.1038\/modpathol.3800986_bib14","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.1365-2559.2006.02478.x","article-title":"The human renal lymphatics under normal and pathological conditions","volume":"49","author":"Ishikawa","year":"2006","journal-title":"Histopathology"},{"key":"10.1038\/modpathol.3800986_bib15","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1002\/dvdy.10163","article-title":"Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate","volume":"225","author":"Hong","year":"2002","journal-title":"Dev Dyn"},{"key":"10.1038\/modpathol.3800986_bib16","doi-asserted-by":"crossref","first-page":"2020","DOI":"10.1002\/dvdy.21200","article-title":"Lymphatic development in mouse small intestine","volume":"236","author":"Kim","year":"2007","journal-title":"Dev Dyn"}],"container-title":["Modern Pathology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/3800986.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/3800986","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0893395222034688?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0893395222034688?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/3800986.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T01:11:00Z","timestamp":1760231460000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0893395222034688"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,2]]}},"alternative-id":["S0893395222034688"],"URL":"https:\/\/doi.org\/10.1038\/modpathol.3800986","relation":{},"ISSN":["0893-3952"],"issn-type":[{"value":"0893-3952","type":"print"}],"subject":[],"published":{"date-parts":[[2008,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Podoplanin is a useful diagnostic marker for epithelioid hemangioendothelioma of the liver","name":"articletitle","label":"Article Title"},{"value":"Modern Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/modpathol.3800986","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2008 United States & Canadian Academy of Pathology.","name":"copyright","label":"Copyright"}]}}