{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T09:06:51Z","timestamp":1791104811361,"version":"4.1.0"},"reference-count":14,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2001,11,1]],"date-time":"2001-11-01T00:00:00Z","timestamp":1004572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2001,11,1]],"date-time":"2001-11-01T00:00:00Z","timestamp":1004572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T00:00:00Z","timestamp":1673395200000},"content-version":"vor","delay-in-days":7741,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["mp.uscap.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Modern Pathology"],"published-print":{"date-parts":[[2001,11]]},"DOI":"10.1038\/modpathol.3880447","type":"journal-article","created":{"date-parts":[[2004,4,14]],"date-time":"2004-04-14T13:02:08Z","timestamp":1081947728000},"page":"1126-1132","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":88,"title":["Integrin \u03b1v\u03b23 Expression in Colon Carcinoma Correlates with Survival"],"prefix":"10.1016","volume":"14","author":[{"given":"Alain","family":"Vonlaufen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guido","family":"Wiedle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bettina","family":"Borisch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Birrer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Luder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beat A","family":"Imhof","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1038\/modpathol.3880447_bib1","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/74651","article-title":"Mechanisms of angiogenesis and arteriogenesis","volume":"6","author":"Carmeliet","year":"2000","journal-title":"Nat Med"},{"key":"10.1038\/modpathol.3880447_bib2","first-page":"65","article-title":"The role of angiogenesis in tumor growth","volume":"3","author":"Folkman","year":"1992","journal-title":"Semin Cancer Biol"},{"key":"10.1038\/modpathol.3880447_bib3","first-page":"89","article-title":"Tumor interactions with the vasculature: angiogenesis and tumor metastasis","volume":"1032","author":"Blood","year":"1990","journal-title":"Biochim Biophys Acta"},{"key":"10.1038\/modpathol.3880447_bib4","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/BF00046839","article-title":"Structure, function and biological properties of integrin \u03b1v\u03b23 on human melanoma cells","volume":"10","author":"Cheresh","year":"1991","journal-title":"Cancer Metastasis Rev"},{"key":"10.1038\/modpathol.3880447_bib5","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1083\/jcb.142.2.595","article-title":"A role for the \u03b1v\u03b23 integrin in the transmigration of monocytes","volume":"142","author":"Weerasinghe","year":"1998","journal-title":"J Cell Biol"},{"key":"10.1038\/modpathol.3880447_bib6","doi-asserted-by":"crossref","first-page":"2482","DOI":"10.1073\/pnas.93.6.2482","article-title":"Ligand occupancy of the \u03b1v\u03b23 integrin is necessary for smooth muscle cells to migrate in response to insulin-like growth factor I","volume":"93","author":"Jones","year":"1996","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1038\/modpathol.3880447_bib7","doi-asserted-by":"crossref","first-page":"2655","DOI":"10.1242\/jcs.108.7.2655","article-title":"An antagonist of integrin \u03b1v\u03b23 prevents maturation of blood vessels during embryonic neovascularization","volume":"108","author":"Drake","year":"1995","journal-title":"J Cell Sci"},{"key":"10.1038\/modpathol.3880447_bib8","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1172\/JCI118227","article-title":"Antiintegrin \u03b1v\u03b23 blocks human breast cancer growth and angiogenesis in human skin","volume":"96","author":"Brooks","year":"1995","journal-title":"J Clin Invest"},{"key":"10.1038\/modpathol.3880447_bib9","unstructured":"StataCortp. Stata statistical software. Release 5.0. College Station, TX: Stata Corporation; 1997."},{"key":"10.1038\/modpathol.3880447_bib10","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","article-title":"Nonparametric estimation from incomplete observations","volume":"53","author":"Kaplan","year":"1958","journal-title":"J Am Stat Assoc"},{"key":"10.1038\/modpathol.3880447_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/bjc.1977.1","article-title":"Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analyses and examples","volume":"35","author":"Peto","year":"1977","journal-title":"Br J Cancer"},{"key":"10.1038\/modpathol.3880447_bib12","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.2517-6161.1972.tb00899.x","article-title":"Regression models and life tables","volume":"34","author":"Cox","year":"1972","journal-title":"J R Stat Soc B"},{"key":"10.1038\/modpathol.3880447_bib13","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1172\/JCI6869","article-title":"The role of \u03b1v integrins during angiogenesis: insights into potential mechanisms of action and clinical development","volume":"103","author":"Eliceiri","year":"1999","journal-title":"J Clin Invest"},{"key":"10.1038\/modpathol.3880447_bib14","first-page":"2625","article-title":"Vascular integrin \u03b1v\u03b23: A new prognostic indicator in breast cancer","volume":"4","author":"Gasparini","year":"1998","journal-title":"Clin Cancer Res"}],"container-title":["Modern Pathology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/3880447.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/3880447","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0893395222036614?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0893395222036614?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/3880447.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T01:13:38Z","timestamp":1760231618000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0893395222036614"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,11]]},"references-count":14,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2001,11]]}},"alternative-id":["S0893395222036614"],"URL":"https:\/\/doi.org\/10.1038\/modpathol.3880447","relation":{},"ISSN":["0893-3952"],"issn-type":[{"value":"0893-3952","type":"print"}],"subject":[],"published":{"date-parts":[[2001,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Integrin \u03b1v\u03b23 Expression in Colon Carcinoma Correlates with Survival","name":"articletitle","label":"Article Title"},{"value":"Modern Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1038\/modpathol.3880447","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2001 United States & Canadian Academy of Pathology.","name":"copyright","label":"Copyright"}]}}