{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:00:00Z","timestamp":1762430400721},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2010,2,23]],"date-time":"2010-02-23T00:00:00Z","timestamp":1266883200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2010,2,23]],"date-time":"2010-02-23T00:00:00Z","timestamp":1266883200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Psychiatry"],"published-print":{"date-parts":[[2011,3]]},"DOI":"10.1038\/mp.2010.2","type":"journal-article","created":{"date-parts":[[2010,2,23]],"date-time":"2010-02-23T09:09:41Z","timestamp":1266916181000},"page":"242-244","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Flight behaviour in humans is intensified by a candidate genetic risk factor for panic disorder: evidence from a translational model of fear and anxiety"],"prefix":"10.1038","volume":"16","author":[{"given":"A M","family":"Perkins","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U","family":"Ettinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S C R","family":"Williams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Reuter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Hennig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P J","family":"Corr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,2,23]]},"reference":[{"key":"BFmp20102_CR1","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1001\/archpsyc.62.6.593","volume":"62","author":"RC Kessler","year":"2005","unstructured":"Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE . Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 2005; 62: 593\u2013603.","journal-title":"Arch Gen Psychiatry"},{"key":"BFmp20102_CR2","unstructured":"American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th edn. (DSM-IV) American Psychiatric Association: Washington, DC, USA, 1994."},{"key":"BFmp20102_CR3","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1176\/appi.ajp.157.4.493","volume":"157","author":"JM Gorman","year":"2000","unstructured":"Gorman JM, Kent JM, Sullivan GM, Coplan JD . Neuroanatomical hypothesis of panic disorder, revised. Am J Psychiatry 2000; 157: 493\u2013505.","journal-title":"Am J Psychiatry"},{"key":"BFmp20102_CR4","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1007\/BF02246145","volume":"120","author":"G Griebel","year":"1995","unstructured":"Griebel G, Blanchard DC, Agnes RS, Blanchard RJ . Differential modulation of antipredator defensive behavior in Swiss-Webster mice following acute or chronic administration of imipramine and fluoxetine. Psychopharmacology 1995; 120: 57\u201366.","journal-title":"Psychopharmacology"},{"key":"BFmp20102_CR5","doi-asserted-by":"publisher","first-page":"12617","DOI":"10.1523\/JNEUROSCI.2696-09.2009","volume":"29","author":"AM Perkins","year":"2009","unstructured":"Perkins AM, Ettinger U, Davis R, Foster R, Williams SCR, Corr PJ . Effects of Lorazepam and citalopram on human defensive reactions: ethopharmacological differentiation of fear and anxiety. J Neurosci 2009; 29: 12617\u201312624.","journal-title":"J Neurosci"},{"key":"BFmp20102_CR6","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1097\/00041444-200503000-00004","volume":"15","author":"E Maron","year":"2005","unstructured":"Maron E, Nikopensius T, K\u00f5ks S, Altm\u00e4e S, Heinaste E, Vabrit K et al. Association study of 90 candidate gene polymorphisms in panic disorder. Psychiatr Genet 2005; 15: 17\u201324.","journal-title":"Psychiatr Genet"},{"key":"BFmp20102_CR7","doi-asserted-by":"publisher","first-page":"1529","DOI":"10.1016\/j.janxdis.2008.03.006","volume":"22","author":"HK Yoon","year":"2008","unstructured":"Yoon HK, Yang JC, Lee HJ, Kim YK . The association between serotonin-related gene polymorphisms and panic disorder. J Anxiety Disord 2008; 22: 1529\u20131534.","journal-title":"J Anxiety Disord"},{"key":"BFmp20102_CR8","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1177\/0013164402062004005","volume":"62","author":"LLB Barnes","year":"2002","unstructured":"Barnes LLB, Harp D, Jung WS . Educ Psychol Meas 2002; 62: 603\u2013618.","journal-title":"Educ Psychol Meas"},{"key":"BFmp20102_CR9","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1016\/j.pnpbp.2007.05.008","volume":"31","author":"A Serretti","year":"2007","unstructured":"Serretti A, Calati R, Giegling I, Hartmann AM, M\u00f6ller HJ, Colombo C et al. 5-HT2A SNPs and the Temperament and Character Inventory. Prog Neuropsychopharmacol Biol Psychiatry 2007; 31: 1275\u20131281.","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"BFmp20102_CR10","doi-asserted-by":"publisher","first-page":"2053","DOI":"10.2174\/092986707781368450","volume":"14","author":"A Serretti","year":"2007","unstructured":"Serretti A, Drago A, De Ronchi D . HTR2A gene variants and psychiatric disorders: a review of current literature and selection of SNPs for future studies. Curr Med Chem 2007; 14: 2053\u20132069.","journal-title":"Curr Med Chem"},{"key":"BFmp20102_CR11","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1176\/appi.ajp.160.4.636","volume":"160","author":"II Gottesman","year":"2003","unstructured":"Gottesman II, Gould TD . The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 2003; 160: 636\u2013645.","journal-title":"Am J Psychiatry"}],"container-title":["Molecular Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/mp20102.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/mp20102","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/mp20102.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T02:47:08Z","timestamp":1648781228000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/mp20102"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2,23]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,3]]}},"alternative-id":["BFmp20102"],"URL":"https:\/\/doi.org\/10.1038\/mp.2010.2","relation":{},"ISSN":["1359-4184","1476-5578"],"issn-type":[{"value":"1359-4184","type":"print"},{"value":"1476-5578","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,2,23]]},"assertion":[{"value":"23 February 2010","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}